Abstract: The present invention relates to a body insertable device having an outer body being bent; and an inner body positioned inside the outer body, having an accommodation space in which the resource soured is accommodated, and being capable of rotating inside the outer body, wherein a radiation emission direction is continuously adjusted by rotation of the inner body.

Abstract: This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (e.g., one or more replicating oncolytic viruses) to treat cancer in a mammal (e.g., a human) identified as having a cancer likely to respond to oncolytic virotherapy are provided.

Abstract: The present invention provides aryl isonitrile compounds that have antibacterial properties. More specifically, the aryl isonitrile compounds of the present invention are potent inhibitors of drug resistant strains of Staphylococcus aureus.

Abstract: The present disclosure generally relates to a combination dry powder inhaler (DPI) formulation of Ciprofloxacin and Colistin through co-spray drying, particularly to a co-sprayed colistin and Ciprofloxacin dry powder inhaler for the treatment of various bacterial infections. Methods of use and composition matters are within the scope of this disclosure.

Abstract: Systems, methods, and other techniques for monitoring, including non-invasive monitoring, of biological markers based on the interaction, temporal association, or coincidence of brain activity and periphery activity in a mammal are provided. Systems and methods for generating a behavioral state-independent representation of cardiac activity and for identifying cardiac events and/or brain-periphery, e.g., brain-cardiac, temporal associations useful as biomarkers of disease such as, e.g., neurologic disease, in a mammal are also provided.

Abstract: The present invention provides an image encoding method and an image decoding method. The image decoding method, according to the present invention, comprises the steps of: determining a transformation performing region; segmenting the determined transformation performing region into at least one sub-transform block by using at least one of quadtree segmentation and binary tree segmentation; and performing inverse transformation on the at least one sub-transform block.

Abstract: A magneto-plasmonic nanostructure is disclosed. The structure includes a substrate, and a magneto-plasmonic stack, comprising a nano-sized plasmonic resonator, a nanomagnet, and a capping layer, wherein the nano-sized plasmonic resonator is configured to receive circularly polarized light at an intensity to thereby increase normal component of plasmon-generated opto-magnetic field, HOM,z, at least at the interface of one of i) the nano-sized plasmonic resonator and the nanomagnet, or ii) the nanomagnet and the capping layer, whereby the HOM,z direction is perpendicular to the rotational direction of the circularly polarized light and the nanomagnets in the magneto-plasmonic stack switches its magnetic moment in response to a change of the HOM,z direction in response to a change of the rotational direction of the circularly polarized light.

Abstract: The present invention relates to a composition for promoting mitochondrial biogenesis, which includes azelaic acid as an active ingredient. It was confirmed that azelaic acid is a compound mainly contained in cereals and natural products and has the advantage of no or little side effects, and mitochondrial autophagy and mitochondrial DNA synthesis in cells are induced, thereby ultimately having activity of increasing mitochondrial density. Therefore, azelaic acid can be used for the treatment of mitochondrial dysfunction-associated disease by the failure of homeostasis control of the mitochondria, for example, mitochondrial activity or the decrease in the number of mitochondria.

Abstract: This present application disclosed a series of selective adenylyl cyclase 1 (AC1) inhibitors, compounds having a formula or a pharmaceutically acceptable salt thereof, as a pain therapeutic. Those compounds may provide an effective method of treatment for chronic/inflammatory pain. Those compounds may also prevent opioid dependence and/or reduce opioid dependence. Both method and composition matters are within the scope of this invention.

Abstract: Provided herein are luminescent probes of formula I: and complexes thereof for the detection of cancer cells.

Abstract: The present disclosure relates to a series of biodegradable amino-ester lipid-like nanoparticles. In some embodiments, the biodegradable amino-ester lipid-like nanoparticles are used in methods for the delivery of nucleic acids.

Abstract: In an example, a method is described that includes dividing an input image into a plurality of strips, where each strip is smaller than a whole of the input image. A plurality of binary images is then generated, where each of the binary images corresponds to one of the strips. Connected component labeling is performed on the binary images, one binary image at a time. An object map for the input image is then generated based on the results of the connected component labeling.

Abstract: An ultrasound system and a clutter filtering method thereof are provided. The clutter filtering method includes: transmitting an ultrasound signal to an object; receiving a reflection signal reflected from the object; performing a singular value decomposition (SVD) on a plurality of doppler signals constituting the reflection signal; dividing a representation of the object into a plurality of regions according to a result of performing the SVD; determining cutoff frequencies of the plurality of regions according to different methods; and performing clutter filtering on the plurality of regions by using the determined cutoff frequencies.

Abstract: Cell penetrating peptides (CPPs) are established as a strategy to move cargoes into the interior of eukaryotic cells by engaging import machinery on the cell surface. In most cases the CPP is covalently linked to the cargo; it is common to express cargo proteins with a CPP extension. In some experiments a non-specific interactions (e.g., hydrophobic interactions) have been used to form CPP-cargo complexes, but this has numerous drawbacks. Transport is less efficient and the lack of specificity means that other macromolecules in the medium will also be internalized. This application describes the use of specific CPP labeled adaptor proteins that can be used to move a wide variety of cargoes into the cell interior. The prototype adaptor protein is calmodulin; it is small, stable and easily produced, and binds short (17 amino acid) targets with high affinity in the presence of calcium. A cargo produced with a calmodulin binding tag can be internalized efficiently by CPP tagged calmodulin.

Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.

Abstract: The present invention relates to a graphene conjugate fiber and a method for manufacturing same, and more particularly, to a conjugate fiber including graphene and a polymer, wherein a wrinkled structure of the graphene is maintained in a fiber state. The graphene conjugate fiber manufactured thereby has superior mechanical properties, is flexible, and has high utility by being manufactured as a fiber.

Abstract: Disclosed is a loop linked smart morphing actuator. The actuator includes a first area morphed in a first pattern and a second area morphed in a second pattern according to an external signal. The first area includes a first unit cell morphed in a first direction. The second area includes a second unit cell morphed in a second direction. The first unit cell and the second unit cell may be configured in a loop type knit structure. The second direction is opposite to the first direction, the second pattern is a pattern which has a symmetrical relationship with the first pattern and is provided opposite to the first pattern. In regard to a structure or a shape, provided is an actuator including a knit structure for realizing various driving forms which cannot be predicted through predetermined first and second patterns or a simple combination thereof.

Abstract: Disclosed herein are a method and device for cloaking an acoustic wave. A method for cloaking an acoustic wave according to an embodiment of the present invention includes: transforming an acoustic propagation mathematical model, predetermined for the propagation of an acoustic wave, into an acoustic wave cloaking mathematical model corresponding to an electromagnetic wave mathematical model predetermined for an electromagnetic wave and including a time variable for time dependency, based on a correlation between the acoustic propagation mathematical model and the electromagnetic wave mathematical model; obtaining a target characteristic of a meta-material by using the acoustic wave cloaking mathematical model; and blocking a region including a target object, from an acoustic wave by disposing the meta-material having the obtained target characteristic to surround the region.

Abstract: The present invention relates to a use of a human small leucine zipper protein in the osteogenesis procedure. More specifically, sLZIP increases the transcriptional activity of Runx2 and inhibits the transcriptional activity of PPAR?2, thereby increasing the osteoblast differentiation, so that sLZIP performs an important role in the osteogenesis procedure, and thus can be used as a marker for treating bone disease and developing new medicines.

Abstract: ‘R13-5-3’ is a new Ruellia simplex plant distinguished by having excellent performance under partial sun and in containers, medium-sized purple-violet flowers with a violet corolla tube, average plant height at 54 cm, profuse branching, and no fruit production, as disclosed.