Abstract: Disclosed herein are improved methods for the preparation of oseltamivir, and intermediates useful thereto.

Abstract: A shade selection program is disclosed that predicts the shade choice with the smallest CIEDE2000 color difference for dental composite resin restorations when given a backing and target shade. By utilizing generated regression models, a database of spectral reflectance information, and principles of Kubelka-Munk layering, a highly accurate shade selection program was designed. Additionally, a blending model for quantification of color adjustment potential was developed. Systems and methods for correlating RGB data from the VITA Linearguide 3D Master and VITA Bleached Guide 3D Master shade guides with their spectroradiometric correlates through a regression model while indicating a methodology for validation of accuracy of digital imaging systems are disclosed.

Abstract: A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying and treating JAM-C positive B-cell lymphoma patients with anti-JAM-C antibodies is provided. Recombinant antibody molecules that specifically bind to JAM-C are also disclosed.

Abstract: A method comprising, in a cloud computing system: receiving a new job at the cloud computing system; sampling VMs (Virtual Machines) of the cloud computing system for the load currently handled by each of the VMs; if the load currently handled by the VMs is within operational bounds, sending the new job to one of the VMs which currently handles the highest load compared to other ones of the VMs; and if the load currently handled by the VMs is beyond operational bounds, sending the new job to one of the VMs which currently handles the lowest load compared to other ones of the VMs.

Abstract: The present invention relates to an apparatus for estimating an arrival-angle of a reception signal and a beam-forming apparatus in a radio wave receiver, such as radar. More specifically, the present invention relates to an apparatus for accurately estimating an arrival-angle of a reception signal, or an apparatus for performing the beam-forming of a reception signal by using a multi-reception array antenna, by using a reference value that is obtained by calculating the degree of distortion of the magnitude and phase of a signal for each reception angle.

Abstract: A sensor that can be used for real time monitoring of load and structural health in engineering structures is provided. The sensor may include a patch with a portion of an optical fiber embedded therein. There may also be triboluminescent materials dispersed within the patch, on and/or near the portions of the optical fiber embedded in the patch. There may be micro-excitors located in proximity to the triboluminescent materials and on the surface of the optical fiber. Loading events and/or damage to the monitored structure may result in a triboluminescent emission from the triboluminescent material that can be guided via the optical fiber. Analysis of the triboluminescent emission may provide information on the magnitude of the applied load as well as the occurrence, severity and location of damage in the structure.

Abstract: The present disclosure generally relates to a process for hydroboration of an alkene or alkyne using ammonia borane (AB). In particular, the present invention relates to hydroboration of an alkene or alkyne in the presence of air or moisture, and a clean process for facile preparation of an alcohol by oxidizing the organoborane so formed with hydrogen peroxide. The products, including aminodialkylboranes, ammonia trialkylborane complexes, as well as various alcohols so prepared, are within the scope of this disclosure.

Abstract: A method of preparing a biological composite matrix system includes combining tissue microparticles with a curable medium. The tissue microparticles are formed by pulverizing tissue, sorting the pulverized tissue particles, and decellularizing the pulverized tissue particles. The tissue microparticles are then mixed with the curable medium and the resulting composite is cured to form a microparticle-medium composite matrix. The microparticle-medium composite matrix is compressed to increase the strength of the matrix and to increase the density of the microparticles to a predetermined density.

Abstract: Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing elements. The arrangements further include a frame configured to encase the plurality of the kinetic energy absorbing elements and the battery cells. In some arrangements the frame and/or the kinetic energy absorbing elements can be made of topologically interlocked materials.

Abstract: Provided herein are indole-2-carboxamide compounds useful for the treatment of non-tuberculosis bacterial infections. Exemplary compounds provided herein are useful for the treatment of non-tuberculosis mycobacterial infections. Methods for preparing the indole-2-carboxamide compounds are also provided.

Abstract: Systems and methods are described for performing navigation-assisted medical procedures such as biopsies, surgeries and pathology procedures by obtaining location information of an item of interest located within at least a portion of a subject; sensing position information of a moveable device; determining a relative position of the moveable device to the item of interest using the location information of the item of interest and the position information of the moveable device; and providing feedback based on the relative position of the moveable device to the item of interest that can be used to change the relative position of the moveable device to the item of interest.

Abstract: Flexible electrical devices are provided that include a coated inner carbon nanotube electrode that has an exterior surface, an outer carbon nanotube electrode disposed on the exterior surface of the coated inner carbon nanotube electrode, and an overlap region in which the coated inner carbon nanotube electrode and the outer carbon nanotube electrode overlap one another, in which the device has a fiber-like geometry and first and second electrode ends. Methods are provided for fabricating an electrical component that includes a flexible electrical component having a fiber-like geometry and includes carbon nanotube electrodes.

Abstract: A vehicle and method for controlling the same may include a speed detector configured to detect driving speed of the vehicle, a detection sensor configured to detect a target vehicle around the vehicle and obtain information about at least one of position and speed of the target vehicle, and a controller configured to determine a steering-based avoidance path for the vehicle to avoid the target vehicle by being steered, determine a maximum lateral acceleration of the vehicle for the vehicle to avoid the target vehicle in the steering-based avoidance path, and send a control signal for steering-based avoidance of the vehicle to avoid a collision with the target vehicle based on the determined maximum lateral acceleration.

Abstract: The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment. The scaffold has an effect of promoting proliferation or differentiation of stem cells, and therefore, can be used as a stem cell culture scaffold. The scaffold enables cell attachment/detachment without temporal or spatial restrictions, thus enabling cell patternization.

Abstract: Tensioned metastable fluid detectors are disclosed that minimize false positive detection events. The methods involve the use of new fluids that provide improved neutron-alpha fission detection at reduced tension states. The rate of spin is also increased using a new protocol that avoids the creation of liquid imbalances in the arms of a CTMFD (centrifugally tensioned metastable fluid detector). The disclosed CTMFD radiation detection system includes a detector assembly containing a detection fluid, a base, a safety enclosure, a motor and motor mounting bracket, speed sensors, a cooling system that includes an air inlet and outlet and a safety enclosure. The CTMFD radiation detection system can include a plurality of independent detector arms having fluids with distinct Pneg requirements such that the range of detectable radiation is increased. Also disclosed are methods for detecting radiation using the disclosed CTMFD radiation detection system. Motor speed calibration procedures are also disclosed.

Abstract: A heart valve therapeutic device has an elongate anchor wherein the anchor has a stiffness to hold its shape and location to support the valve element. The anchor may have a stylet or a shaped or stiff collar arranged to provide a desired shape to the anchor and it may be lockable. A prosthetic valve element has leaflets and is supported on the anchor by coupler at a desired location. There is an actuator for changing relative axial position of the proximal and distal couplers on the anchor. The anchor stiffness may be sufficient to provide sufficient support to resist axial forces from the ventricle in use without necessarily having a fixing element engaging heart tissue. The prosthetic leaflets may extend proximally and radially outwardly, so that there is excellent co-apting of the native leaflets (NL) against the prosthetic leaflets.

Abstract: A composition for prevention or treatment of pulmonary fibrosis comprising chromenone derivatives represented by Formula I of the present invention or pharmaceutically acceptable salts thereof as an active ingredient, produces altered heat shock protein 27 (HSP27) dimers, thereby preventing normal HSP27 non-phosphorylated polymers from performing a chaperone function and reducing a cell protection function that chaperone originally performs. Thus the inventive composition has a remarkable inhibitory effect on pulmonary fibrosis, in particular, an irradiation-induced pulmonary fibrosis phenomenon.

Abstract: A system and method for generating a spatial map of parameters that describe the mechanically-induced harmonic motion information present within a magnetic resonance elastography (MRE) data set is provided. A first temporal harmonic signal is estimated using a graph-cut based optimization strategy, and can subsequently be used to generate a spatial map of mechanical parameters. The MRE data set is used to estimate the harmonic. The spatial map is of a mechanical parameter derived from the estimated harmonic.

Abstract: A metal nanolaminate includes a plurality of units stacked in a longitudinal direction of the metal nanolaminate. Each of the units includes a first layer and a second layer stacked in the longitudinal direction. The first layer includes a first metal material formed of a first metallic element and the second layer includes the first metal material and a second metal material formed of a second metallic element. Each of the first layer and the second layer has a thickness of at least 5 nm but less than 100 nm in the longitudinal direction.

Abstract: A new Hibiscus plant named ‘RutHib1’ is characterized by a combination of good form, medium vigor, predominately purple foliage, white flowers with a red eye, and good tolerance to Alternaria, Cercospora, and Phytophthora pathogens.