Patents Assigned to Foundation
  • Patent number: 9488623
    Abstract: A method of inspecting a structure is disclosed. The method generally comprises selecting a search region of a dispersion curve of the structure corresponding to one or more inspection parameters. The search region comprises at least one guided wave mode activation point not located on the dispersion curve. The method further comprises activating, using an inspection system comprising at least one transducer, a plurality of activation points located within the search region of the dispersion curve and identifying an optimal activation point for the one or more inspection parameters. The optimal activation point comprises at least one of the plurality of activation points producing an optimal response for the one or more inspection parameters.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: November 8, 2016
    Assignee: The Penn State Research Foundation
    Inventors: Joseph L. Rose, Jason Philtron
  • Patent number: 9488620
    Abstract: Apparatuses and methods are disclosed for determining whether a structure of bonded layers includes locations where the layers are weakly bonded. Embodiments include evaluating the frequency response of the structure in response to vibrational inputs. Alternate embodiments include evaluating the non-linear response of the structure using a modal analysis. Further embodiments include obtaining the vibrational information with an accelerometer contacting the structure, while additional embodiments include exciting the structure with an impact force, which may be applied at multiple locations on the structure's surface. Still further embodiments include performing a MAC, COMAC, and/or FRF analysis. Still other embodiments include varying the amplitude of the input vibration. Additional embodiments locate the areas of weakened bonding. Still other embodiments include methods and apparatuses for simulating a laminated structure with defective bonding, such as kiss bonding.
    Type: Grant
    Filed: March 15, 2012
    Date of Patent: November 8, 2016
    Assignee: Purdue Research Foundation
    Inventors: Douglas E. Adams, Nathan D. Sharp, Ronald Sterkenburg
  • Patent number: 9489742
    Abstract: An apparatus, a method and a non-transitory computer-readable recording medium for detecting a moving object using a depth map is provided. The apparatus includes a segment image generator unit that generates a segment image to distinguish each object using a depth image of a current input frame; a background image generator unit that generates a current background image by applying a moving average method to the depth image and a background image of a previous input frame; and a moving mask generator unit that generates a moving mask by comparing the depth image with the current background image to thereby find moving parts in the depth image.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: November 8, 2016
    Assignees: Samsung Electronics Co., Ltd, Dong-A University Foundation for Industry-Academic Cooperation
    Inventors: Jeong-Ho Han, Jung-Seop Kim, Bong-Soon Kang, Hyun-Joong Kang, Kyoung-Hoon Jang, Ho-Sang Cho
  • Patent number: 9488600
    Abstract: An electrically conductive nanoscale sensor includes a nanoscale pore that may be employed as a first antenna to provide precise localized measurements of the impedance-altering characteristics of a molecule such as DNA or RNA or the like passing through the pore. The use of radiofrequency measurements via a second antenna communicating with the first antenna promises high-speed analysis of long molecules (polymers).
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: November 8, 2016
    Assignees: Wisconsin Alumni Research Foundation, University of Hamburg
    Inventors: Robert H. Blick, Abhishek Bhat, Paul Gwozdz
  • Patent number: 9486333
    Abstract: A prosthetic sock for a patient to wear over a residual limb is provided. The prosthetic sock includes an inner layer configured to fit over at least a portion of the residual limb of the patient. A foam layer is disposed on an outer surface of the inner layer. The foam layer compensates for changes in shape or volume of the residual limb within the prosthetic sock by changing shape in a manner effective to maintain a secure fit between the residual limb and a prosthetic socket of a prosthetic limb.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: November 8, 2016
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Ben Wang, Chun Zhang, Changchun Zeng, Leslie David Kramer, Arlene Gillis
  • Patent number: 9486343
    Abstract: A pre-loaded stent graft delivery device and stent graft, the stent graft delivery device. The stent graft has at least one fenestration or side arm and the fenestration is preloaded with an indwelling guide wire. Indwelling access sheaths are provided within auxiliary lumens of a pusher catheter and dilators are preloaded into the access sheaths along with the indwelling guide wire. A handle assembly at a distal end of the guide wire catheter. The handle includes a multiport manifold with access ports to the auxiliary lumens in the pusher catheter. Upon deployment of the stent graft into the vasculature of a patient, the indwelling guide wire can be used to facilitate cathertization of a side branch or target vessel through the fenestration or be used to stabilize the access sheath during catheterization, advancement of the access sheath into the target vessel and deployment of a covered or uncovered stent therein through the access sheath.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: November 8, 2016
    Assignees: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Krasnodar Ivancev, David Ernest Hartley, Werner D. Ducke, Erik Rasmussen
  • Patent number: 9489474
    Abstract: The invention provides a model for generating predicted action potentials of an electrically active cell. The disclosed model includes three operatively coupled submodels. A first submodel contains Hodgkin-Huxley elements generating action potentials based on electrical equivalent circuits. A second submodel is based on reaction kinetics of cell metabolism and is operatively coupled with the first submodel. A third submodel is based on Boolean dynamics representing signaling and associated cellular processes and is operatively coupled with the first and second submodels. The invention includes storing a library of calculated action potentials and associated cellular parameters generated by the model, applying a stimulus to the electrically active cell in vitro so that the cell generates an action potential; and comparing the cell-generated action potential with those stored in the library, wherein a match is predictive of the cellular point of action of the applied stimulus according to the parameters stored.
    Type: Grant
    Filed: February 7, 2011
    Date of Patent: November 8, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: James Hickman, Peter Molnar, Frank Sommerhage, Jonathan Ernest Hood, Jerry Jenkins
  • Patent number: 9486541
    Abstract: This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: November 8, 2016
    Assignees: Mayo Foundation for Medical Education and Research, VIB VZW, Universteit Antwerpen, The University of British Columbia, The University of Manchester
    Inventors: Michael L. Hutton, Matthew Charles Baker, Jennifer Mae Gass, Rosa Rademakers, Jason Eriksen, Stuart M. Pickering-Brown, Ian Reid Alexander Mackenzie, Howard Feldman, Samir Kumar-Singh, Christine Van Broeckhoven, Marc Cruts, Ashley Diane Cannon
  • Patent number: 9487856
    Abstract: A composite structure, comprising a cemented carbide substrate (e.g., tungsten carbide substrate cemented with cobalt, such as WC—Co), a thin interlayer disposed over the substrate, and a contiguous diamond film disposed over the interlayer, as well as processes of preparing such a composite structure and uses thereof, are provided. The composite structure is characterized by at least one of a substrate binder concentration of at least 2 percents by weight, interlayer thickness less than 20 microns, a homogenous interlayer made substantially of crystalline chromium nitride, a low to null binder concentration in the interlayer, and a high co-adhesion of the diamond film to the interlayer and the interlayer to the substrate.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: November 8, 2016
    Assignee: Technion Research & Development Foundation Limited
    Inventor: Alon Hoffman
  • Patent number: 9489582
    Abstract: Methods, systems, and processor-readable media for video anomaly detection based upon a sparsity model. A video input can be received and two or more diverse descriptors of an event can be computed from the video input. The descriptors can be combined to form an event matrix. A sparse reconstruction of the event matrix can be performed with respect to an over complete dictionary of training events represented by the diverse descriptors. A step can then be performed to determine if the event is anomalous by computing an outlier rejection measure on the sparse reconstruction.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: November 8, 2016
    Assignees: Xerox Corporation, The Penn State Research Foundation
    Inventors: Raja Bala, Aaron M. Burry, Vishal Monga, Xuan Mo
  • Patent number: 9490486
    Abstract: A method of synthesizing activated electrocatalyst, preferably having a morphology of a nanostructure, is disclosed. The method includes safely and efficiently removing surfactants and capping agents from the surface of the metal structures. With regard to metal nanoparticles, the method includes synthesis of nanoparticle(s) in polar or non-polar solution with surfactants or capping agents and subsequent activation by CO-adsorption-induced surfactant/capping agent desorption and electrochemical oxidation. The method produces activated macroparticle or nanoparticle electrocatalysts without damaging the surface of the electrocatalyst that includes breaking, increasing particle thickness or increasing the number of low coordination sites.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: November 8, 2016
    Assignees: Brookhaven Science Associates, LLC, The Research Foundation for the State University of New York
    Inventors: Radoslav R. Adzic, Kuanping Gong, Yun Cai, Stanislaus Wong, Christopher Koenigsmann
  • Publication number: 20160320395
    Abstract: The invention relates to materials and methods for diagnosing liver tumor types, and assessing patient prognosis. Specifically, but not exclusively, the invention concerns the determination of marker protein which enable primary liver tumors to be identified and classified according to the latest WHO classification. Particularly, the invention provides potential markers proteins which allow non-neoplastic and neoplastic hepatocytes and biliary epithelial cells to be distinguished. This allows grading of tumor differentiation to be refined and differential diagnosis of primary liver tumors and pathogenesis of sub-types of cholangiocarcinoma.
    Type: Application
    Filed: November 13, 2014
    Publication date: November 3, 2016
    Applicants: Electrophoretics Limited, King's College Hospital NHS Foundation Trust
    Inventors: Malcolm Andrew Ward, Ian Hugo Pike, David James Britton, Vikram Mitra, Nigel David Heaton, Yoh Zen, Alberto Quaglia
  • Publication number: 20160320464
    Abstract: A radiofrequency (RF) coil for use in a magnetic resonance imaging (MRI) system using a plurality of RF coils includes a main loop coil including a plurality of electrical conductors, and an auxiliary loop coil disposed around the plurality of electrical conductors and including a plurality of electrical conductors.
    Type: Application
    Filed: December 26, 2014
    Publication date: November 3, 2016
    Applicants: Samsung Electronics Co., Ltd., Samsung Life Public Welfare Foundation
    Inventors: Kyoungnam KIM, Yeonhyeon CHOE
  • Publication number: 20160317551
    Abstract: Provided herein are methods of treating a subject with cancer comprising administering to the subject a death receptor agonist. Also provided herein are methods of screening a breast cancer cell for responsiveness to a DR5 agonist. Further provided herein are antibodies that selectively bind an N-terminal CARD of DDX3, a DDX3 lacking an N-terminal CARD, and an 80 kDa baculovirus TAP repeat (BIR).
    Type: Application
    Filed: July 20, 2016
    Publication date: November 3, 2016
    Applicant: The UAB Research Foundation
    Inventors: Donald J. Buchsbaum, Tong Zhou, Albert F. LoBuglio
  • Publication number: 20160321384
    Abstract: Simulation systems, manufacturing systems, software products and controllers are provided with multi-scale modeling in which a coarse mesh and a fme mesh that models a stimulus are decoupled. The fine mesh can be moved within the coarse mesh with a cut and paste operation. The coarse mesh is updated by sparsely propagated effects through the coarse mesh. Simulations of the invention can be conducted in real-time, and be used as controllers in manufacturing systems, such as additive manufacturing systems. A number of efficient methods are provided for solving meshing determinations that arise from movement of a stimulus modeled within a fine mesh.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Applicant: University of Louisville Reasearch Foundation, Inc.
    Inventors: Deepankar Pal, Nachiket Patil, Brent Stucker
  • Publication number: 20160317535
    Abstract: The present invention relates to methods of preventing or treating skin necroptosis diseases, including administering to subjects receptor-interacting protein kinase-3 (RIP3)-mixed lineage kinase domain-like protein (MLKL) pathway blockers or dabrafenib, and method of diagnosing of skin necroptosis diseases, including detecting phosphorylated MLKL. The RIP3-MLKL pathway blockers according to the present invention directly suppress RIP3 overexpressing in skin necroptosis diseases, or inhibit phosphorylation and translocation to plasma membranes of MLKL, subsequently induced therefrom, thereby effectively preventing skin cell death via necroptosis. Thus, the present invention can prevent or treat a variety of skin diseases caused by necroptosis.
    Type: Application
    Filed: February 5, 2016
    Publication date: November 3, 2016
    Applicant: Ajou University Industry-Academic Cooperation Foundation
    Inventor: You Sun KIM
  • Publication number: 20160317604
    Abstract: The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic cationic peptide. The aromatic cationic peptide has (a) at least one net positive charge; (b) a minimum of three amino acids; (c) a maximum of about twenty amino acids, (d) a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; (e) a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 3a or 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1; and (f) at least one tyrosine or tryptophan amino acid.
    Type: Application
    Filed: December 1, 2015
    Publication date: November 3, 2016
    Applicant: Cornell Research Foundation, Inc.
    Inventor: Hazel H. Szeto
  • Publication number: 20160319285
    Abstract: Methods and compositions for inhibiting tumorigenicity both in vitro and in vivo in a subject in need thereof, comprising administering an effective amount of an anti-miR-494 nucleic acid construct sufficient to target one or more tumor suppressor genes (TSGs) are described. Activation of the ERK1/2 pathway is a major determinant of diverse cellular processes and cancer development and is responsible for the transcription of several important miRNAs. Described herein is a link between the ERK1/2 pathway and BIM expression through miR-494. This ERK1/2 pathway regulates apoptosis and cell proliferation through miR-494 and mechanisms responsible for TRAIL resistance. Materials and methods related to the study and treatment of cancer are described.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 3, 2016
    Applicant: Ohio State Innovation Foundation
    Inventors: Carlo M. Croce, Giulia Romano
  • Publication number: 20160323233
    Abstract: Disclosed are a method and a system for providing a traffic information-based social network service, which provides traffic information between vehicles or between a vehicle and a user terminal through a social network service, wherein traffic information is shared between vehicles or between a vehicle and the mobile device of a person through a social network service.
    Type: Application
    Filed: December 22, 2014
    Publication date: November 3, 2016
    Applicant: Korea National University of Transportation Industry-Academic Cooperation Foundation
    Inventors: Seok Il SONG, Dong Gun LIM, Cheol MUN
  • Publication number: 20160319241
    Abstract: Well-defined, xeno-free culture media which comprise a TGF-beta isoform or the chimera formed between IL6 and the soluble IL6 receptor (IL6RIL6), which are capable of maintaining stem cells, and particularly, human embryonic stem cells, in an undifferentiated state are provided. Also provided are cell cultures comprising the culture media and the stem cells and methods of expanding and deriving embryonic stem cells in such well-defined, xeno-free culture media. In addition, the present invention provides methods of differentiating ESCs or EBs formed therefrom for the generation of lineage specific cells.
    Type: Application
    Filed: July 14, 2016
    Publication date: November 3, 2016
    Applicant: Technion Research & Development Foundation Limited
    Inventors: Michal AMIT, Joseph ITSKOVITZ-ELDOR