Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.
Type:
Application
Filed:
July 4, 2016
Publication date:
October 27, 2016
Applicant:
Technion Research & Development Foundation Limited
Abstract: A system for constructing a support column includes a mandrel with an upper portion and a tamper head. A feed tube extends through the mandrel for feeding flowable material to the head. The tamper head includes a lower enlarged chamber with a reducing surface at an upper portion and includes a plurality of chain links for compacting material and restricting upward flow of aggregate. The tamper head is of a size providing an enclosed region for allowing cementitious materials to be placed therein. A non-moveable sealed top plate and a separate flowable material supply tube is included via a sealed connection. A pressure gauge for monitoring air pressure within the tube portion is included and allows a support column including a cementitious inclusion on top of an expanded base to be built with a known unitary expanded base volume calculated based on pressure drop indications.
Abstract: Described herein are methods and systems related to the use of the pre-existing ion injection pathway of a mass spectrometer to perform beam-type collision-activated dissociation, as well as other dissociation methods. The methods can be practiced using a wide range of mass spectrometer configurations and allows MSn experiments to be performed on very basic mass spectrometers, even those without secondary mass analyzers and/or collision cells. Following injection and selection of a particular ion type or population, that population can be fragmented via beam-type collision-activated dissociation (CAD), as well as other dissociation methods, using the pre-existing ion injection pathway or inlet of a mass spectrometer. For CAD applications, this is achieved by transmitting the ions back along the ion injection pathway with a high degree of kinetic energy. As the ions pass into the higher pressure regions located in or near the atmospheric pressure inlet, the ions are fragmented and then trapped.
Abstract: A gate driver, including multiple stages of gate driving circuits, wherein each stage of the gate driving circuits includes an input part configured to generate a Q node signal in response to a carry signal of one of previous stages and a clock signal, the Q node signal being applied to Q node, an output part configured to output a gate output signal to a gate output terminal in response to the Q node signal, and a charge sharing part connected to the gate output terminal of a present stage and a gate output terminal of one of next stages, the charge sharing part configured to operate charge-sharing between the gate output signal of the present stage and a gate output signal of one of the next stages in response to a select signal.
Type:
Grant
Filed:
June 23, 2014
Date of Patent:
October 25, 2016
Assignees:
Samsung Display Co., Ltd., Industry-University Cooperation Foundation Hanyang University
Inventors:
Oh-Kyong Kwon, Yeong-Keun Kwon, Jong-Hee Kim, Ji-Sun Kim, Jae-Keun Lim, Chong-Chul Chai
Abstract: This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus.
Type:
Grant
Filed:
March 31, 2008
Date of Patent:
October 25, 2016
Assignee:
The Research Foundation for The State University of New York
Inventors:
Eckard Wimmer, Steve Skiena, Steffen Mueller, Bruce Futcher, Dimitris Papamichail, John Robert Coleman, Jeronimo Cello
Abstract: An antenna includes a first body having an array of resonators; a spacer adjacent to the first body, and a second body adjacent to the spacer such that the spacer is between the first and second bodies. The first body can be configured as an artificial metasurface ground plane and the second body can be configured as a monopole.
Abstract: A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
Abstract: An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound.
Type:
Grant
Filed:
June 24, 2014
Date of Patent:
October 25, 2016
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Systems and methods which utilize spread spectrum sensing on live circuits to obtain information regarding a circuit under test are provided. In some embodiments S/SSTDR testing may be utilized to obtain R, L, C and Z measurements from circuit components. In yet further embodiments, these measurements may be utilized to monitor the output of sensors on a circuit.
Abstract: A digital counter may include a first count unit suitable for outputting a first bit signal having a constant level in response to a first clock signal, a second count unit suitable for outputting a second bit signal having a constant level in response to a second clock signal, and a third count unit suitable for outputting a third bit signal toggling in response to the second clock signal, and performing a count operation.
Type:
Grant
Filed:
December 8, 2014
Date of Patent:
October 25, 2016
Assignees:
SK Hynix Inc., Industry-University Cooperation Foundation Hanyang University
Inventors:
Byong Deok Choi, Jong Seok Kim, Don Ku Lee
Abstract: Novel alpha-hydrogen substituted nitroxyl compounds and their corresponding oxidized (oxoammonium cations) and reduced (hydroxylamine) forms, and the use of such compounds, inter alia, for oxidation of primary and secondary alcohols to aldehydes and ketones, respectively; resolution of racemic alcohols; desymmetrization of meso-alcohol; as radicals and spin trapping reagents; and as polymerization agents. Processes for preparing the novel nitroxyl/oxoammonium/hydroxylamine compounds from the corresponding amines, and certain novel amine derivatives and their uses. The compounds and amine precursors are useful as ligands for transition metals and as organocatalysts in e.g., aldol reactions.
Type:
Grant
Filed:
August 6, 2014
Date of Patent:
October 25, 2016
Assignee:
Technion Research and Development Foundation Ltd.
Abstract: A low-pressure chemical vapor deposition (LPCVD) apparatus and a thin-film deposition method thereof. The apparatus comprises a reaction furnace, having reaction gas input pipelines respectively arranged at a furnace opening part and a furnace tail part. During thin film deposition, each reaction gas is synchronously introduced into the reaction furnace through the input pipeline at the furnace opening part and the input pipeline at the furnace tail part.
Type:
Grant
Filed:
December 3, 2012
Date of Patent:
October 25, 2016
Assignee:
University of Utah Research Foundation
Inventors:
Xunhui Wang, Xiao Wu, Qijun Guo, Jianchao Fan
Abstract: An organic light-emitting diode includes a first electrode, a second electrode, and an organic layer disposed between the first electrode and the second electrode. The organic layer includes an emission layer. The organic layer also includes at least one amine-based compound and at least one pyrene-based compound. The organic layer may include a first emission layer and a second emission layer, and the amine-based compound may be in the first emission layer and the pyrene-based compound may be in the second emission layer.
Type:
Grant
Filed:
July 11, 2013
Date of Patent:
October 25, 2016
Assignees:
Samsung Display Co., Ltd., Seoul National University R&DB Foundation
Inventors:
Se-Hun Kim, Hwan-Hee Cho, Myoung-Ki Kim, Mi-Kyung Kim, Chang-Woong Chu, Jong-In Hong
Abstract: The present invention provides HIV-derived lentivectors which are safe, highly efficient, and very potent for expressing transgenes for human gene therapy, especially, in human hematopoietic progenitor cells as well as in all other blood cell derivatives. The lentiviral vectors comprise a self-inactivating configuration for biosafety and promoters such as the EF1? promoter as one example. Additional promoters are also described. The vectors can also comprise additional transcription enhancing elements such as the wood chuck hepatitis virus post-transcriptional regulatory element. These vectors therefore provide useful tools for genetic treatments such as inherited and acquired lympho-hematological disorders, gene-therapies for cancers especially the hematological cancers, as well as for the study of hematopoiesis via lentivector-mediated modification of human HSCs.
Abstract: The present invention relates to a two-dimensional code-type time-temperature indicator the color or shape of which changes in accordance with time and temperature conditions, and to a method for manufacturing the time-temperature indicator, to a quality guarantee system using the time-temperature indicator, and to a quality guarantee method using the quality guarantee system. The time-temperature indicator comprises: nanobeads containing a microorganism for generating lactic acids using nutrient components, an indicating agent for indicating the change in color by means of the generated lactic acids, an immobilization material for immobilizing the microorganism, the indicating agent, and the nutrient components; a base having a bonding layer; and a cover film.
Type:
Grant
Filed:
June 27, 2012
Date of Patent:
October 25, 2016
Assignee:
Dongguk University Industry-Academic Cooperation Foundation
Abstract: Flexible electrical devices are provided that include a coated inner carbon nanotube electrode that has an exterior surface, an outer carbon nanotube electrode disposed on the exterior surface of the coated inner carbon nanotube electrode, and an overlap region in which the coated inner carbon nanotube electrode and the outer carbon nanotube electrode overlap one another, in which the device has a fiber-like geometry and first and second electrode ends. Methods are provided for fabricating an electrical component that includes a flexible electrical component having a fiber-like geometry and includes carbon nanotube electrodes.
Type:
Grant
Filed:
August 28, 2014
Date of Patent:
October 25, 2016
Assignee:
Florida State University Research Foundation, Inc.
Abstract: Methods and systems for optimizing the process of heat and/or mass transfer operations in packed beds and embodiments of applications of the methods are disclosed herein below. In one instance, the method results in the profile of the quantity representative of the heat and/or mass transfer operation having a propagating substantially sharp front.
Type:
Grant
Filed:
January 10, 2012
Date of Patent:
October 25, 2016
Assignee:
The Research Foundation of the City University of New York
Abstract: The new variety ‘TH-921’ is provided. The new and distinct variety ripens around early May in southern Georgia and late May in middle Georgia. The fruit of the new variety ‘TH-921’ are firm with good flavor and scar. The new variety ‘TH-921’ is vigorous with an estimated chilling requirement of about 500 to 550 hours at or below approximately 7° C. The asexually reproduced variety is reliably propagated vegetatively.
Type:
Grant
Filed:
July 10, 2015
Date of Patent:
October 25, 2016
Assignee:
University of Georgia Research Foundation, Inc.
Abstract: ‘UFR-5’ is a new and distinct allotetraploid citrus rootstock for tree size control and improved disease resistance. ‘UFR-5’ has shown a positive reaction to the Huanglongbing disease (HLB, or citrus greening disease) in multiple experimental field trials. Scion trees grafted on this rootstock show a reduced frequency of infection and reduced disease symptoms once infected as compared to commercial diploid rootstocks.