Abstract: An object of the present invention is to provide a simple purifying method, measuring method, and kit. The present invention is an oxytocin purifying method including treating a sample with an acid or a salt thereof, and treating the sample treated with the acid or the salt thereof with a hydrophobic carrier, and related to the purifying method, measuring method including the purifying method, and kit, in which the acid or the salt thereof is at least one or more acids or salts thereof selected from the group consisting of hydrochloric acid, acetic acid, sulfuric acid, sodium hydrogensulfate, potassium hydrogensulfate, lithium hydrogensulfate, ammonium sulfate, and a mixture thereof, and the hydrophobic carrier is a hydrophobic carrier having at least one or more functional groups on the surface, selected from the group consisting of an alkyl group having 4 to 6 carbon atoms, an alkylene glycol group, and a phenyl group.

Abstract: Provided is a method for producing a reversible addition-fragmentation chain transfer polymerization polymer, which includes continuously rotating a reaction container accommodating a mixed solution which contains a monomer and a reversible addition-fragmentation chain transfer agent around a rotation axis inclined with respect to a vertical direction using a rotating photopolymerization reactor, while stirring a liquid pool of the mixed solution, to spread a mixed solution emerging from the liquid pool in a form of a film on an interior wall of the reaction container, and irradiating the mixed solution spread in the form of a film with light from a light source disposed outside the reaction container.

Abstract: Provided is a method for producing a thiocarbonylthio group-removed polymer, including a step of irradiating a mixed solution which contains a polymer having a thiocarbonylthio group at a terminal of a main chain and contains at least one hydroxyl group-containing compound of an alcohol compound or a phenol compound to remove the thiocarbonylthio group from the polymer.

Abstract: An object of the present invention is to provide a binder which exhibits excellent dispersibility of a conductive assistant; a slurry composition and an electrode, each of which uses this binder; and an electricity storage device which is provided with this electrode. The present invention relates to a binder for an electricity storage device, in which a loss tangent tan ? in a linear region of an aqueous dispersion liquid of 0.5% by mass of the binder and 4.6% by mass of a conductive assistant satisfies tan ?>1 in a strain dispersion measurement under measurement conditions of a measurement temperature of 25° C. and a frequency of 1 Hz, and the conductive assistant is an acetylene black having an average particle diameter of 30 nm or more and 40 nm or less and a specific surface area of 65 m2/g or more and 70 m2/g or less; a slurry composition and an electrode, each of which uses this binder; an electricity storage device which is provided with this electrode; and the like.

Abstract: The invention provides gastroenterological cancer determination methods that involve contacting a specimen, an antibody 1 that recognizes an ? chain of human haptoglobin, and an antibody 2 that recognizes a ? chain of human haptoglobin and does not recognize human haptoglobin in which an S—S bond is cleaved to form a complex 1, or contacting the specimen and two antibodies selected from the antibodies 2 that recognize a ? chain of human haptoglobin and do not recognize human haptoglobin in which an S—S bond is cleaved to form a complex 2. A determination is made based on the measurement of complex 1 or 2. Alternatively, the specimen and two antibodies selected from the antibodies 1 that recognize an ? chain of human haptoglobin are contacted to form a complex 3, and a determination is made by comparing the measurement results of complex 1 or 2 with complex 3.

Abstract: An object of the present invention is to provide a light- or heat-curing method by which a cured product (crosslinked product or resin) can be prepared in a simple method even in a case where filler is contained in a large amount; a curable resin composition which is used in the curing method; and the like.

Abstract: The invention provides a primer pair for detecting Pneumocystis jirovecii, which has a low probability of false negatives and is excellent in sensitivity, a method for detecting Pneumocystis jirovecii using the same, and a reagent kit therefor. The primer pair for detecting Pneumocystis jirovecii is (i) a combination of a forward primer consisting of a base sequence represented by SEQ ID NO: 1 and a reverse primer consisting of a base sequence represented by SEQ ID NO: 2, (ii) a combination of the forward primer consisting of the base sequence represented by SEQ ID NO: 1 and a reverse primer consisting of a base sequence represented by SEQ ID NO: 4, or (iii) a combination of a forward primer consisting of a base sequence represented by SEQ ID NO: 3 and the reverse primer consisting of the base sequence represented by SEQ ID NO: 2.

Abstract: A method for assisting the diagnosis of Alzheimer's disease, comprising: measuring an amount of extracellular vesicles having phosphatidylserine and tetraspanin, or the amount of extracellular vesicles having phosphatidylserine and tetraspanin and an amount of extracellular vesicles having tetraspanin, in a biological specimen derived from a subject; and determining that the subject has Alzheimer's disease using the amount of extracellular vesicles having phosphatidylserine and tetraspanin, or a ratio of the amount of extracellular vesicles having phosphatidylserine and tetraspanin to the amount of extracellular vesicles having tetraspanin as an indicator.

Abstract: A method for assisting the diagnosis of Parkinson's disease, including: measuring an amount of extracellular vesicles having phosphatidylserine and tetraspanin, or the amount of extracellular vesicles having phosphatidylserine and tetraspanin and an amount of extracellular vesicles having tetraspanin, in a biological specimen derived from a subject; and determining that the subject has Parkinson's disease using the amount of extracellular vesicles having phosphatidylserine and tetraspanin, or a ratio of the amount of extracellular vesicles having phosphatidylserine and tetraspanin to the amount of extracellular vesicles having tetraspanin as an indicator.

Abstract: The present invention relates to a binder for electricity storage devices containing a salt of a polymer containing structural units derived from (i) an ethylenically unsaturated carboxylic acid monomer and (ii) an ethylenically unsaturated monomer having at least one group selected from a hydroxy group, a dialkylamino group, an acetyl group, a sulfo group, a phosphate group, or a cyano group and neutralized with a monoamine, a polyvalent amine having an amine value of less than 21, and/or an onium hydroxide; a slurry composition and an electrode, each of which uses this binder; an electricity storage device which is provided with this electrode; and the like.

Abstract: An object of the present invention is to provide an excellent binder agent composition solving problems such as the decrease in a charge/discharge capacity that occurs in a case where a silicon-containing active material is used, a slurry composition and an electrode in which the binder agent composition is used, and a method for preparing the electrode.

Abstract: An object of the present invention is to provide a means capable of stably storing an extracellular vesicle. The present invention relates to a storage stabilizer for an extracellular vesicle, which contains a copolymer containing a monomer unit derived from vinylpyrrolidone and a monomer unit derived from vinyl acetate, or a polymer having a monomer unit derived from vinylpyrrolidone such as polyvinylpyrrolidone and relates to a storage stabilization method for an extracellular vesicle, which includes cryopreserving an extracellular vesicle in the presence of the polymer.

Abstract: The present invention relates to a method for determining prostate carcinoma, including obtaining a ratio 1 between an amount of a free prostate specific antigen and an amount of a free PSA having an ?(2,3) glycan, the free PSA having an ?(2,3) glycan being a free prostate specific antigen having a glycan in which a terminal sialic acid residue of the glycan is ?(2,3)-linked to a second galactose residue from a terminal of the glycan, in a sample derived from a subject; obtaining a ratio 2 between the ratio 1 and a volume of the prostate of the subject; and determining prostate carcinoma based on the obtained ratio 2.

Abstract: An object of the present invention is to provide a novel molecule which has high specificity to CLDN-5 and recognizes an extracellular domain of CLDN-5. The object is achieved by an antibody which specifically recognizes a three-dimensional structure or a primary structure of an extracellular domain of a Claudin-5 protein.

Abstract: The invention relates to a pancreatic cancer determination marker, a pancreatic cancer determination method, a method for acquiring data for determining a pancreatic cancer, a pancreatic cancer determination kit, and the like.

Abstract: An object of the present invention is to provide a copolymer which is capable of forming a viscous aqueous solution having a desired viscosity in the presence of an electrolyte, in particular, a polyvalent electrolyte, a thickening agent comprising the copolymer, and a cosmetic preparation comprising the copolymer. The present invention relates to an acrylic acid ester (A)/compound (B) copolymer, comprising, as constitutional components, an acrylic acid ester (A) and a compound (B), wherein the acrylic acid ester (A) is represented by the general formula [1], and the compound (B) has, in each molecule, a polymerizable unsaturated group and any functional group selected from the group consisting of a carboxyl group, a sulfo group, and a phosphate group, and a weight ratio of the acrylic acid ester (A) and the compound (B), which is (A)/(B), is 9.0/91.0 to 28.5/71.

Abstract: Provided is an aqueous dispersion of colored particles suitable for colorants for writing instrument inks, inkjet inks, painting materials, aqueous coatings, and the like. The aqueous dispersion of colored particles includes a polymer having at least a unit of a monomer derived from a dye having a polymerizable unsaturated group. The monomer derived from the dye is preferably derived from the compound represented by General Formula (1) below: where Dye represents a dye residue, R1 represents a hydrogen atom or a methyl group, Y2 represents —O— or —NR10—, where R10 represents a hydrogen atom or an alkyl group, A1 represents an alkylene group which is unsubstituted or substituted by at least one group selected from —OCO—, —COO—, —NHCONH—, and the like in the chain thereof and/or at the terminal thereof, and/or a hydroxy group.

Abstract: The invention provides a method for determining a psychiatric disorder, as well as a marker for determining a psychiatric disorder, such as depressive disorder, bipolar disorder, schizophrenia, or dementia with high reliability (accuracy and precision). The method involves measuring amounts of (A) anthranilic acid and (B) tryptophan, kynurenine, or 3-hydroxyanthranilic acid in a sample, calculating a ratio of the amounts (A) and (B), and determining a psychiatric disorder based on the ratio of the amounts (A) and (B).

Abstract: Quenchers of the related art do not have a quenching ability high enough to sufficiently inhibit the emission of fluorescence from fluorescence compounds. Therefore, the present invention aims to provide a quencher which can sufficiently quench the fluorescence from fluorescent compounds including xanthene-based dyes. The present invention relates to a quencher formed of a compound represented by the following general formula (1), and the like.

Abstract: The invention provides a primer set for detecting Chlamydia trachomatis containing (a) a first primer pair composed of a forward primer consisting of a base sequence represented by SEQ ID NO: 5 and (b) a reverse primer consisting of a base sequence represented by SEQ ID NO: 6, as well as a method for detecting Chlamydia trachomatis using the primer set, and a reagent kit therefor.