Abstract: The present invention relates to a compound represented by the general formula (A), a base- and/or radical-generating agent comprising the compound, and so on.

Abstract: An object of the present invention is to provide a fragment antibody which can be conveniently produced as one having antigen-binding activity, and which has a greater ability to crystallize itself alone or as a complex with an antigen molecule than that of Fv-clasp (v1) even in a case where the fragment antibody is obtained in an E. coli expression system. The present invention relates to a fragment antibody including a complex of a peptide (VH(112C)-SARAH) in which an N-terminus of a SARAH domain is linked to a C-terminus of a heavy chain domain (VH region) of an antibody, and an amino acid residue of antibody residue 112 according to Chothia numbering scheme in the VH region is mutated to cysteine; and a peptide (VL-SARAH(37C)) in which an N-terminus of a SARAH domain is linked to a C-terminus of a light chain domain (VL region) of an antibody, and an amino acid residue at position 13 from the C-terminus in the SARAH domain is mutated to cysteine.

Abstract: A quencher is disclosed having a compound represented by the following general formula (1): wherein R5 each independently represent a halogen atom, an alkyl group, an alkoxy group, an alkylthio group, an amino group having a substituent or not having a substituent, a hydroxy group, an aryl group, an aryloxy group, or an arylalkyl group; R6 represents a group having a polymerizable unsaturated group, a hydroxy group, or the like; Y1 represents an oxygen atom, or the like; An? represents an anion; Ar1 represents a specific ring structure; * and ** represent binding positions; Ar2 represents a benzene ring, a naphthalene ring, or an anthracene ring; n1 represents a specific integer; and the following structure (1-10) in the general formula (1) is an asymmetric structure; (wherein R5, Y1, Ar1, Ar2, n1, * and ** are the same as described above.).

Abstract: It is an object of the present invention to provide an electrolytic solution having high oxidation decomposition potential, where dissolution and deposition of magnesium proceed repeatedly and stably, using a non-nucleophilic alkoxide-type magnesium salt.

Abstract: The present invention relates to an oligonucleotide, comprising a part or the entire of the nucleotide sequence shown in any of SEQ ID NO: 1 to SEQ ID NO: 15, or a part or the entire of the sequence complementary to the nucleotide sequence shown in any of SEQ ID NO: 1 to SEQ ID NO: 15, wherein the oligonucleotide is capable of hybridizing with the nucleotide sequence of Mycobacterium intracellulare (M. intracellulare) gene; a primer or a probe for the detection of M. intracellulare which comprises said oligonucleoride; and a method for detection of M. intracellulare using said primer and/or the probe.

Abstract: A method of producing an organic compound, which contains a step of performing a deodorization step using a flow reaction in a flow passage to remove, from a reaction liquid, a malodorous material generated or remaining in a reaction step, wherein the organic compound is an industrially useful compound.

Abstract: The object of the present invention is to generalize and improve DNA-binding proteins using PPR. There is provided a protein that contains one or more PPR motifs having a structure of the following formula 1, wherein one PPR motif (Mn) contained in the protein is a PPR motif having a specific combination of amino acids corresponding to a target DNA base or target DNA base sequence as the three amino acids of No. 1 A.A., No. 4 A.A., and No. “ii” (?2) A.A, and satisfies at least one selected from the group consisting of the following conditions (a) to (h): (a) No. 7 A.A. of the PPR motif (Mn) is isoleucine (I); (b) No. 9 A.A. of the PPR motif (Mn) is alanine (A); (c) No. 10 A.A. of the PPR motif (Mn) is tyrosine (Y); (d) No. 18 A.A. of the PPR motif (Mn) is lysine (K), arginine (R), or histidine (H); (e) No. 20 A.A. of the PPR motif (Mn) is glutamic acid (E), or aspartic acid (D); (f) No. 29 A.A. of the PPR motif (Mn) is glutamic acid (E), or aspartic acid (D); (g) No. 31 A.A.

Abstract: An object of the present invention is to provide a copolymer which is capable of forming a viscous aqueous solution having a desired viscosity in the presence of an electrolyte, in particular, a polyvalent electrolyte, a thickening agent comprising the copolymer, and a cosmetic preparation comprising the copolymer. The present invention relates to an acrylic acid ester (A)/compound (B) copolymer, comprising, as constitutional components, an acrylic acid ester (A) and a compound (B), wherein the acrylic acid ester (A) is represented by the general formula [1], and the compound (B) has, in each molecule, a polymerizable unsaturated group and any functional group selected from the group consisting of a carboxyl group, a sulfo group, and a phosphate group, and a weight ratio of the acrylic acid ester (A) and the compound (B), which is (A)/(B), is 9.0/91.0 to 28.5/71.

Abstract: The invention provides a primer set for detecting Chlamydia trachomatis containing (a) a first primer pair composed of a forward primer consisting of a base sequence represented by SEQ ID NO: 5 and (b) a reverse primer consisting of a base sequence represented by SEQ ID NO: 6, as well as a method for detecting Chlamydia trachomatis using the primer set, and a reagent kit therefor.

Abstract: It is an object of the present invention to provide a cyanine-based coloring composition having higher heat resistance, as compared with a conventional coloring composition. The present invention relates to a compound represented by the following general formula (1), a polymer having a monomer unit derived from the compound, along with a coloring composition, a coloring composition for a color filter, and a colored resin comprising the above-described compound or the above-described polymer.

Abstract: An object of the present invention is to provide a photocuring method, which makes it possible to rapidly and efficiently obtain a crosslinked product (resin), a compound used in the photocuring method, and a photocuring resin composition containing the compound. The present invention relates to a photocuring method, which comprises a step 1 and a step 2 performed after the step 1, a compound used in the photocuring method, and a photocuring resin composition containing the compound. Step 1: this is a step in which in the presence of (A) compound having a carbonyl group generating a radical by photoirradiation and a carboxyl group decarboxylated by photoirradiation, (B) silane coupling agent having a mercapto group or a (meth)acryl group is reacted with (C) water under acidic conditions to obtain (D) silane compound having a mercapto group or a (meth)acryl group and at least one silanol group.

Abstract: An object of the present invention is to provide a novel Pca determination method and a Pca malignancy determination method. The present invention is an invention relating to a “prostate carcinoma determination method, including determining the ratio of the amount of free prostate specific antigen, which has a glycan in which the terminal sialic acid residue of the glycan is ?(2,3)-linked to a second galactose residue from the terminal of the glycan, to the amount of free PSA in a biological sample, and then determining that prostate carcinoma is developed or the probability of developing prostate carcinoma is high in the case where the ratio is 40% or higher.

Abstract: A coloring composition having higher heat resistance as compared with the conventional coloring composition, including a compound represented by general formula (1), and a polymer having a monomer unit derived from the compound. (wherein R1 to R4 each independently represent a hydrogen atom, an alkyl group; R7 represents a hydrogen atom or a methyl group; R8 and R9 each independently represent a hydrogen atom or an alkyl group; Y represents a nitrogen atom or a group represented by formula (1-1): A1 represents an alkylene group having at least one group selected from —O—, —OCO—, —COO—, —NHCO—, —CONH—, —NHCONH— and an arylene group in the chain; A2 represents —NH— or —O—; An ?represents an anion containing an aryl group having an electron-withdrawing substituent; n represents an integer of 0 to 3; R8 and R9 may form a cyclic structure of a 5 to 6 membered ring together with —N—(CH2)n—Y— bonding thereto.

Abstract: A compound capable of providing a composition having high storage stability without reacting with a base-reactive compound, even when stored in a mixed state with the base-reactive compound, as well as capable of generating a strong base by irradiation of light (active energy rays) or heating. A base generator comprises the compound and a base-reactive composition comprises the base generator and the base-reactive compound. The compound is represented by the general formula (A).

Abstract: An object of the invention is to obtain a biotinylated nucleic acid efficiently, by enhancing dissociation efficiency of biotin in the biotinylated nucleic acid and tamavidin 2 in a tamavidin 2-immobilized insoluble carrier. The inventive method for separating a biotinylated nucleic acid includes (1) contacting a sample containing a biotinylated nucleic acid wherein the biotin is bound to the nucleic acid with a insoluble carrier on which tamavidin is immobilized (a tamavidin-immobilized insoluble carrier) to form a complex of the biotinylated nucleic acid and the tamavidin-immobilized insoluble carrier, and (2) separating the biotinylated nucleic acid from the complex in a solution having pH of 7.8 to 9.5 and in the presence of free biotin. The invention also provides a method for separating the biotinylated nucleic acid to which the nucleic acid-binding protein is bound, a method for separating the nucleic acid-binding protein, and a kit for separating the nucleic acid.