Abstract: A human gene, fg01, on chromosome 8, is identified. This gene, and its expression product, human fg01, shares a homology under 70% with the corresponding murine gene, which has been linked to presentation of the Alzheimer's phenotype of A? plaques and hyperphosphorylated tau tangles. Upregulation appears to suppress the Alzheimer's phenotype, which may be effective in preventing the onset of symptoms or progression of symptoms associated with AD. Screening methods are also set forth.

Abstract: A human gene, fg01, on chromosome 8, is identified, as well as a truncated form on chromosome 5. Upregulation appears to suppress the Alzheimer's phenotype, (AB plaques and hyperphosphorylated tau tangles) which may address the onset of symptoms or progression of symptoms associated with AD. Screening methods are also set forth.

Abstract: The present invention relates to boron transporters and, in particular, to boron transporters derived from plants. The present invention also relates to methods that utilise boron transporters, such as methods for modulating boron transport in cells and methods for determining the level or rate of boron transport in a cell or organism on the basis of the expression level of one or more boron transporters.

Abstract: An implant fixture is disclosed. The implant fixture includes an elongated body extending along a longitudinal axis. The elongated body includes a base portion having a non-circular cross section and a receiver adapted to receive a prosthetic. A root portion extends from the base portion away from the receiver. An extension portion extends from the root portion away from the base portion. The extension portion extends primarily along one side of the longitudinal axis. A kit containing a plurality of implant fixtures having different configurations is also disclosed. Further, a method of inserting the implant fixture into a patient is also disclosed. The method uses piezoelectrically generated energy to seat the implant fixture in the patient's bone.

Abstract: A linkage element for a flail chain comprising more than two shank portions and more than two angled portions connecting the shank portions. The shank portions and angled portions define an interior space of the linkage element. A flail chain comprising at least one such linkage element forms a part of a flailing apparatus used to debark trees.

Abstract: An implant fixture is disclosed. The implant fixture includes an elongated body extending along a longitudinal axis. The elongated body includes a base portion having a non-circular cross section and a receiver adapted to receive a prosthetic. A root portion extends from the base portion away from the receiver. An extension portion extends from the root portion away from the base portion. The extension portion extends primarily along one side of the longitudinal axis. A kit containing a plurality of implant fixtures having different configurations is also disclosed. Further, a method of inserting the implant fixture into a patient is also disclosed. The method uses piezoelectrically generated energy to seat the implant fixture in the patient's bone.

Abstract: An adaptable body conditioning apparatus is disclosed having a relatively rigid platform and gripping attachment with a handle and a stem rotatably receivable through an opening at the platform. A flexible material bushing abuts a threaded shaft of the stem and is received in a retention cavity formed in the handle. A flex limiter is threadably engaged on the threaded shaft of the stem and is manually adjustable along the length of the shaft. The limiter is utilized to limit the amount of tilting movement allowed to the handle under the influence of user weight applied at the handle when in use.

Abstract: The invention reflects enhanced antibody expression of an antibody of interest by cell lines transformed by random homozygous gene perturbation methods to either increase or decrease the expression pattern of a gene of the cell line other than the antibody of interest. The transformed cell line exhibits specific productivity rates, SPR, for the RHGP transformed cell liens of 1.5 or more, as compared with the antibody expressing cell line parents prior to transformation by RHGP. A knock out or anti-sense construct may be devised to reduce expression of the target gene, a promoter may be inserter to enhance expression of the target gene. The antibodies expressed by the transformed cell lines exhibit the binding properties of their parent cell lines prior to transformation with RHGP, and increase Total Volumetric Production of said antibody by said cells in a given volume.

Abstract: The present invention relates generally to nucleic acid constructs, which are useful for inserting a nucleotide sequence of interest into a target nucleic acid molecule via homologous recombination. The present invention also relates to methods for producing such constructs.

Abstract: For measuring a brain local activity, a predetermined frequency bandwidth wider than a frequency bandwidth of alpha waves of scalp potentials is divided into a predetermined number of frequency banks each having a fixed frequency width, data of each divided frequency bank is divided into segments of a predetermined duration on a time axis, a Z-score of the subject is determined from a first mean value of normalized power variances determined for the segments and a second mean value of normalized power variances predetermined in the same manner as the first mean value for a predetermined normal person group and a standard deviation of the normalized power variances in the group, and a mean value of the Z-scores determined over all of the frequency banks is mapped on a brain surface for each sensor, whereby a template of a specified brain disorder and likelihood of a subject to a specified brain disorder are calculated.

Abstract: The present invention provides a novel water-soluble keratin derivative and applications thereof. Water-soluble keratin produced by the alkali treatment of feathers, and modified keratin, gives the following useful materials: (1) a high energy wave absorber, (2) a luminescent substrate, (3) a material weatherproofness improver, (4) a water repellant, and (5) a foaming agent.

Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the present invention concerns a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a Harpin-associated Factor G polypeptide (hereinafter termed HpaG”). The present invention also concerns plants having modulated expression of a nucleic acid encoding an HpaG polypeptide, which plants have enhanced yield-related traits relative to control plants. The invention also provides constructs comprising HpaG-encoding nucleic acids, useful in performing the methods of the invention. The present invention also provides a method for enhancing yield-related traits in plants relative to control plants, by modulating (preferably increasing) expression in a plant of a nucleic acid sequence encoding a SWITCH 2/SUCROSE NON-FERMENTING 2 (SWI2/SNF2) polypeptide.

Abstract: Genes relating to resistance to infection by influenza virus are identified. The genes and the gene products (i.e., the polynucleotides transcribed from and polypeptides encoded by the genes) can be used for the prevention and treatment of influenza. The genes and the gene products can also be used to screen agents that modulate the gene expression or the activities of the gene products.

Abstract: A self-calibrating current sensor for sensing the state of the current passing through a load line enclosed within a housing comprises a sensor disposed adjacent the load line for sensing a current passing through the load line, the sensor having an output at which a signal indicative of the level of current passing through the load line is present, the sensor being positioned with the housing, a binary input circuit configured to generate at least one binary signal, the binary input circuit being configured to change the level of the at least one binary signal without the need of opening the housing, and a controller circuit having a first input coupled to the output of the sensor for receiving the signal indicative of the level passing through the supply line and having a second input coupled to the binary input circuit for receiving the at least one binary signal, the controller being configured to provide a signal indicative of the status of the current in the load line on an output.

Abstract: A dental implant fixture is disclosed. The implant fixture includes an elongated body extending along a longitudinal axis. The body has a first end and a second end. The first end includes a top face having a first portion having a first angle extending obliquely with respect to the longitudinal axis and a second portion having a second angle extending obliquely to the longitudinal axis and at an angle relative to the first portion.

Abstract: The present invention is directed to an ergonomic exercise sash which is contoured to fit a torso of a user. Weight members may be placed in a plurality of pockets of the sash to increase the resistance and intensity of exercise.

Abstract: Read the description file of a PCBA without determining and selecting connectors which might be relevant to boundary scan. The description file of the PCBA determines which pins of the connectors on the PCBA should correspond to the pins of a test I/O module. And use the wiring report generated by an auto test program generator to correspond the pins of the test I/O module to the pins of the connectors which are accessed by boundary scan. Thus the IC of the test I/O module would not have any unused pin between any two consecutive pins wired to the connectors of the PCBA.