Patents Assigned to FUND OF THE TEL AVIV MEDICAL CENTER
  • Publication number: 20210187039
    Abstract: A method of producing an implant for fecal transplant (FT), including: introducing fecal materials into a container, and processing the fecal materials to a smaller size in the container. According to some embodiments, the container is in ambient conditions, and the processing in the container includes non-ambient conditions. Optionally, the non-ambient conditions include an atmosphere having at most 18% of O2. Optionally, the method includes adding a liquid into the container, the liquid including a preservative material. Optionally, the liquid includes between 10% to 30% glycerol by volume. Optionally, the method includes sealing the container with a sealing lid after the introducing, and processing the fecal materials in the sealed container. Optionally, the processing of the fecal materials includes cutting the fecal materials by a cutting element to increase an exposed surface area of the fecal materials.
    Type: Application
    Filed: August 20, 2019
    Publication date: June 24, 2021
    Applicants: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center, Fund for Medical Research Development of Infrastructure & Health Services by Barzilai Medical Center
    Inventors: Arie FELDMAN, Nitsan MAHARSHAK, David GALES
  • Publication number: 20210187258
    Abstract: Described embodiments include apparatus (28) that includes a shunt (26). The shunt includes a flared distal portion (40), a flared proximal portion (44), and an intermediate portion (42), disposed between the distal portion and the proximal portion. The apparatus further includes a constricting flexible longitudinal element (38) passing circumferentially along the intermediate portion of the shunt, configured to constrict the intermediate portion of the shunt, and one or more proximal-portion-collapsing flexible longitudinal elements (36) configured to collapse the proximal portion of the shunt. Other embodiments are also described.
    Type: Application
    Filed: March 4, 2021
    Publication date: June 24, 2021
    Applicants: The Medical Research, Infrastructure And Health Services Fund Of The Tel-Aviv Medical Center, V-Wave Ltd.
    Inventor: Gad KEREN
  • Publication number: 20210169395
    Abstract: A system and method are presented for use in monitoring brain activity of a subject. The system comprises a control unit which comprises: a data input utility for receiving measured data comprising data corresponding to signals measured during a certain time period and being indicative of a subject's brain activity originated from locations in the subject's brain during said certain time period, and a processor utility which is configured and operable for processing the measured data and generating data indicative thereof in the form of a multi-parameter function presenting a relation between frequency and time data of the measured signals and for analyzing said relation and identifying a subject-related signature corresponding to the subject's brain neural activity.
    Type: Application
    Filed: November 23, 2020
    Publication date: June 10, 2021
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Talma HENDLER, Nathan INTRATOR, Ilana KLOVATCH, Sivan KINREIH, Yehudit MEIR-HASSON
  • Publication number: 20210161430
    Abstract: Methods and/or systems for diagnosing, monitoring and/or treating persons at risk for falling and/or other pathological conditions. In an exemplary embodiment of the invention, people are diagnosed before they actually start falling. Optionally, the diagnosis includes trying out and identifying one or more fall triggers using virtual reality tools. Optionally or alternatively, treatment includes training the persons using situations and/or triggers which are determined to be relevant for that person.
    Type: Application
    Filed: February 8, 2021
    Publication date: June 3, 2021
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Anat MIRELMAN, Jeffrey M. HAUSDORFF, Nir GILADI
  • Patent number: 10945641
    Abstract: Methods and/or systems for diagnosing, monitoring and/or treating persons at risk for falling and/or other pathological conditions. In an exemplary embodiment of the invention, people are diagnosed before they actually start falling. Optionally, the diagnosis includes trying out and identifying one or more fall triggers using virtual reality tools. Optionally or alternatively, treatment includes training the persons using situations and/or triggers which are determined to be relevant for that person.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: March 16, 2021
    Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Anat Mirelman, Jeffrey M. Hausdorff, Nir Giladi
  • Patent number: 10940296
    Abstract: Described embodiments include apparatus (28) that includes a shunt (26). The shunt includes a flared distal portion (40), a flared proximal portion (44), and an intermediate portion (42), disposed between the distal portion and the proximal portion. The apparatus further includes a constricting flexible longitudinal element (38) passing circumferentially along the intermediate portion of the shunt, configured to constrict the intermediate portion of the shunt, and one or more proximal-portion-collapsing flexible longitudinal elements (36) configured to collapse the proximal portion of the shunt. Other embodiments are also described.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: March 9, 2021
    Assignees: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center, V-Wave Ltd.
    Inventor: Gad Keren
  • Patent number: 10893822
    Abstract: A system and method are presented for use in monitoring brain activity of a subject. The system comprises a control unit which comprises: a data input utility for receiving measured data comprising data corresponding to signals measured during a certain time period and being indicative of a subject's brain activity originated from locations in the subject's brain during said certain time period, and a processor utility which is configured and operable for processing the measured data and generating data indicative thereof in the form of a multi-parameter function presenting a relation between frequency and time data of the measured signals and for analyzing said relation and identifying a subject-related signature corresponding to the subject's brain neural activity.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: January 19, 2021
    Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Talma Hendler, Nathan Intrator, Ilana Klovatch, Sivan Kinreih, Yehudit Meir-Hasson
  • Publication number: 20200408761
    Abstract: A method of diagnosing high grade bladder cancer is provided. The method comprising detecting in a urine sample of a subject in need thereof expression of CD24, wherein an increase in said expression of CD24 above a predetermined threshold as compared to a control sample is indicative of said high grade bladder cancer.
    Type: Application
    Filed: February 28, 2019
    Publication date: December 31, 2020
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Nadir ARBER, Shiran SHAPIRA, Dina KAZANOV
  • Patent number: 10729815
    Abstract: A combined treatment for nerve injury is provided. Accordingly there is provided a composition comprising a hyaluronic acid, a laminin polypeptide, an antioxidant and an anti-gliotic agent. Also provided are matrices and hydrogels of the composition and methods of using same.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: August 4, 2020
    Assignees: Ramot at Tel-Aviv University Ltd., The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Shimon Rochkind, Zvi Nevo
  • Publication number: 20200174004
    Abstract: A method of diagnosing a cancer or a pre-malignant lesion is disclosed. The method comprising determining a level of expression of CD24 on leukocytes comprised in a biological sample of a subject, wherein a level of CD24 on small leukocytes and not on large leukocytes above a predetermined threshold is indicative of the cancer or the pre-malignant lesion. A method of monitoring efficacy of cancer therapy and a kit for diagnosing a cancer or a pre-malignant lesion are also disclosed.
    Type: Application
    Filed: May 21, 2018
    Publication date: June 4, 2020
    Applicant: The Medical Research, Infratructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Nadir ARBER, Shiran SHAPIRA, Diana KAZANOV
  • Publication number: 20200170548
    Abstract: A method of gait data collection, the method comprising collecting movement data, determining from the data a movement parameter that includes a third order derivative of position, comparing the movement parameter with a threshold value, and counting at least a near fall if the movement parameter exceeds the threshold value.
    Type: Application
    Filed: February 3, 2020
    Publication date: June 4, 2020
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Jeffrey M. HAUSDORFF, Nir GILADI
  • Patent number: 10639350
    Abstract: Provided are methods of improving wound healing in a subject by administering a therapeutically effective amount of CD24. Also provided are pharmaceutical compositions which comprise CD24 being in a formulation with a surfactant and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: May 5, 2020
    Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Nadir Arber, Shiran Shapira, Dina Kazanov
  • Publication number: 20200121200
    Abstract: A method and system are provided for continuous monitoring perfusion of an organ or extremity, and for early detection of progressive partial occlusion of arterial blood supply or venous drainage of tissue. The method and system measure a delay in wave propagation of a blood perfusion wave, which is associated with flow of blood through a blood vessel. The delay is correlated to an amount of obstruction in the blood vessel.
    Type: Application
    Filed: June 26, 2018
    Publication date: April 23, 2020
    Applicants: The Medical Research Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Amir Landesberg, Amit Livneh, Yehuda Wolf
  • Publication number: 20200071669
    Abstract: Methods of culturing T cells are provided. Accordingly there is provided a method of culturing T cells comprising culturing T cells in the presence of a T cell stimulator, an exogenous CCL21 and an exogenous ICAM1, thereby culturing the T cells. Also provided are cell cultures, isolated T cells and uses of same.
    Type: Application
    Filed: March 2, 2018
    Publication date: March 5, 2020
    Applicants: Yeda Research and Development Co. Ltd., The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Benjamin GEIGER, Nir FRIEDMAN, Shimrit LIEBER, Zelig ESHHAR, Tova WAKS, An at GLOBERSON LEVIN
  • Publication number: 20200046680
    Abstract: This invention provides small organic molecules useful as therapeutics of neurodegenerative diseases. Small organic molecules that act as inhibitors of bone morphogenetic proteins (BMPs) are useful in the treatment of neuroinflammatory disorders, in particular multiple sclerosis.
    Type: Application
    Filed: April 26, 2018
    Publication date: February 13, 2020
    Applicant: THE MEDICAL RESEARCH, INFRASTRUCTURE AND HEALTH SERVICES FUND OF THE TEL AVIV MEDICAL CENTER
    Inventor: Arnon KARNI
  • Patent number: 10548512
    Abstract: A method of gait data collection, the method comprising collecting movement data, determining from the data a movement parameter that includes a third order derivative of position, comparing the movement parameter with a threshold value, and counting at least a near fall if the movement parameter exceeds the threshold value.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: February 4, 2020
    Assignee: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Jeffrey M. Hausdorff, Nir Giladi
  • Publication number: 20200022895
    Abstract: The invention provides a method for skin expansion utilizing at least one polymer.
    Type: Application
    Filed: July 19, 2018
    Publication date: January 23, 2020
    Applicant: The Medical Research, Infrastructure, and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Amir INBAL, Andrew GREENSMITH, Nir SHANI
  • Publication number: 20190329063
    Abstract: A method for modifying the effect of a drug by application of an activation protocol, comprising: administering a drug according to a treatment protocol; applying an activation protocol in a timed relationship to the administering, for differentially activation of at least one selected brain region; wherein the differentially activation allows the drug to selectively interact with the at least one selected brain region.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 31, 2019
    Applicant: The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Talma HENDLER, Gal RAZ, Roy Itzhak SAR-EL
  • Publication number: 20190117846
    Abstract: A combined treatment for nerve injury is provided. Accordingly there is provided a composition comprising a hyaluronic acid, a laminin polypeptide, an antioxidant and an anti-gliotic agent. Also provided are matrices and hydrogels of the composition and methods of using same.
    Type: Application
    Filed: November 29, 2017
    Publication date: April 25, 2019
    Applicants: Ramot at Tel-Aviv University Ltd., The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Shimon ROCHKIND, Zvi NEVO
  • Patent number: 10265412
    Abstract: The present invention relates in general to the field of enzyme replacement therapy, and specifically to chimeric proteins including protein hormone-therapeutic protein conjugates and fusion proteins, wherein the protein hormone is selected from a protein hormone which is able to cross the blood brain barrier, for the treatment of lysosomal storage diseases, compositions of the same and to methods of use thereof.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: April 23, 2019
    Assignees: Ramot at Tel-Aviv University Ltd., Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science, The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center
    Inventors: Naftali Stern, Ruth Navon, Anthony Futerman, Ari Zimran, Etty Osher