Patents Assigned to Gachon University of Industry-Academic Cooperation Foundation
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Publication number: 20240342306Abstract: Provided are a stem cell-nano anticancer drug complex in which an anticancer drug based on carbon nanotubes (CNT) and gold (Au) nano particles is loaded on the surface of stem cells, which can overcome side effects of conventional stem cells and targeting limitations of nano anticancer drugs and whose anticancer effect is very excellent, the use thereof, and a method for preparing the same.Type: ApplicationFiled: June 21, 2024Publication date: October 17, 2024Applicant: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Dong Woo KHANG, Yeon Kyung LEE, Sang-Woo KIM, Jun-Young PARK
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Patent number: 12042544Abstract: Provided are a stem cell-nano anticancer drug complex in which an anticancer drug based on carbon nanotubes (CNT) and gold (Au) nano particles is loaded on the surface of stem cells, which can overcome side effects of conventional stem cells and targeting limitations of nano anticancer drugs and whose anticancer effect is very excellent, the use thereof, and a method for preparing the same.Type: GrantFiled: April 19, 2018Date of Patent: July 23, 2024Assignee: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Dong Woo Khang, Yeon Kyung Lee, Sang-Woo Kim, Jun-Young Park
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Patent number: 11964241Abstract: A lithium-air battery includes a battery cell and a case configured to accommodate the battery cell. The case includes an inlet communicating with outside and an outlet communicating with outside. At least one of the inlet and the outlet is equipped with a gas separation membrane that includes a matrix including a polymer resin and a metal-organic framework (MOF) dispersed in the matrix. The gas separation membrane has a thickness of 150 ?m or more.Type: GrantFiled: June 14, 2023Date of Patent: April 23, 2024Assignees: Hyundai Motor Company, Kia Corporation, Gachon University of Industry-Academic Cooperation FoundationInventors: Gwang Seok Oh, Jihyun Lee, Minyoung Yoon
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Publication number: 20230394674Abstract: Proposed is a system and method for segmentating brain in MRI images. According to an embodiment, it is possible to overcome limitations that gray matter is estimated to be smaller than the actual size in brain segmentation performed for quantitative analysis of a brain imaged by a magnetic resonance imaging (MRI) scanner and to accurately segment brain images by distinguishing dura mater and veins around the cerebellum by removing a large amount of cranial dura mater, thereby improving accuracy of brain quantitative analysis results and fundamentally increasing diagnostic accuracy for brain lesions.Type: ApplicationFiled: December 1, 2022Publication date: December 7, 2023Applicants: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTERInventors: Jun Young CHUNG, Young NOH, Woo-Ram KIM
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Publication number: 20230365501Abstract: The present invention relates to: a novel 4-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.Type: ApplicationFiled: September 17, 2021Publication date: November 16, 2023Applicants: CNG BIO CO., LTD., CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Jaekyung JUNG, Mi Kyeong LEE, Dae Hee LEE, Jae Kang LEE, Sun Yeou KIM, Da Hye YOON, Seong Min HONG
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Publication number: 20230331672Abstract: The present invention relates to: a novel 6-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.Type: ApplicationFiled: September 17, 2021Publication date: October 19, 2023Applicants: CNG BIO CO., LTD., CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Jaekyung JUNG, Mi Kyeong LEE, Dae Hee LEE, Jae Kang LEE, Sun Yeou KIM, Da Hye YOON, Seong Min HONG
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Publication number: 20230296815Abstract: Disclosed is a light amplifier device comprising a light source emitting a first light; a first lens unit formed under the light source to collect the first light in an opposite direction from the light source; a first filter unit formed under the first lens unit to remove a noise of the first light; an amplifier unit receiving the first light to induce surface plasmon effect and generate second light which is an amplified light; a second filter unit consisted to remove a noise of the second light; and a measurement unit formed in a traveling direction of the second light transmitted through the second lens unit to measure intensity of the second light.Type: ApplicationFiled: October 8, 2020Publication date: September 21, 2023Applicant: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventor: Heong Kyu JU
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Publication number: 20230274421Abstract: Provided are a method for providing information about the diagnosis of a gallbladder polyp and a device for providing information about the diagnosis of a gallbladder polyp using same. The method for providing information about the diagnosis of a gallbladder polyp being implemented by a processor includes the steps of receiving an ultrasound medical image including a gallbladder part of a subject, determining the pathogenesis of a gallbladder polyp in the subject using a first assessment model configured to determine the pathogenesis of a gallbladder polyp on the basis of the ultrasound medical image, and determining characteristics of the gallbladder polyp on the basis of a second assessment model configured to classify characteristics of the gallbladder polyp when the gallbladder polyp is determined in the ultrasound medical image.Type: ApplicationFiled: July 20, 2021Publication date: August 31, 2023Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTERInventors: Jae Hee CHO, Sung Ill JANG, Kwang Gi KIM, Young Jae KIM, Eui Joo KIM
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Patent number: 11726082Abstract: The present invention relates to a method for screening drug candidates for treating a disease using the interaction between calcium and phosphatidylinositol phosphate. Particularly in the present invention, it was confirmed that the concentration of calcium was increased in the obesity induced insulin resistance animal model and the increased calcium concentration inhibited the migration of Akt protein containing PH domain and the signal transduction, while the protein containing C2 domain was able to migrate to the cell membrane by binding to calcium/PIP complex even under the condition of high calcium concentration. Therefore, the investigation of the interaction between calcium and PIP can be a useful method for screening of drug candidates for treating metabolic disease, cancer or hypertension.Type: GrantFiled: November 21, 2018Date of Patent: August 15, 2023Assignees: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTERInventors: Byung-Chul Oh, Jin Ku Kang, Ok Hee Kim, Cheol Soon Lee
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Patent number: 11529334Abstract: The present invention relates to a pharmaceutical composition comprising a STT compound as an active ingredient for the prevention or treatment of Parkinson's disease. STT showed neuroprotective effect and apoptosis recovery effect in the Parkinson's disease cell model, restored the reduced motility in the MPTP animal model, and was shown to significantly protect dopamine cells, so it can be used for the prevention and treatment of Parkinson's disease.Type: GrantFiled: April 17, 2020Date of Patent: December 20, 2022Assignees: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTER, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITYInventors: Seung Yoon Nam, Jinhyuk Lee, Joo-Won Jeong
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Patent number: 11517745Abstract: Provided is an artificial retina system for improving contrast sensitivity. The artificial retina system includes an artificial retina which is installed under the retina and includes a plurality of photodiode cells and a microcomputer. The microcomputer compares, with at least one reference value, the magnitude of an electric signal outputted from a photodiode in each of the photodiode cells. The microcomputer controls to amplify or reduce the electric signal outputted by each of the photodiode cells according to the result of comparison. Visual cells corresponding to each of the photodiode cells can be stimulated with an electric signal controlled by the microcomputer.Type: GrantFiled: March 8, 2018Date of Patent: December 6, 2022Assignees: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Seong-woo Kim, Jungsuk Kim
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Patent number: 11484716Abstract: Disclosed is an artificial retinal stimulator and an artificial retinal device which are for providing image jittering. The artificial retinal stimulator for providing the image jittering includes: a photodiode configured to sense light stimulation and generate a current based on an intensity of the stimulation; a pulse generator configured to generate a pulse to be provided to a corresponding stimulation electrode on the basis of the current coming from the photodiode; a switch configured to connect an output terminal of the pulse generator and ground; and a jittering switch configured to determine whether to transfer the generated pulse to the corresponding stimulation electrode or to transfer to a stimulation electrode corresponding to another artificial retinal stimulator. According to the present disclosure, an image jittering function capable of emulating an eye blinking effect is provided, so that it is possible to enable a low vision patient to see images better.Type: GrantFiled: October 5, 2018Date of Patent: November 1, 2022Assignees: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Seong Woo Kim, Jung Suk Kim
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Patent number: 11389516Abstract: The present invention relates to a composition comprising the UNE-L domain of leucyl-tRNA synthetase as an effective ingredient for increasing muscle. More particularly, the UNE-L domain of LRS according to the present invention, which is a region that controls activity of Vps34, activates mTORC1 involved in protein synthesis and increases myocyte differentiation and muscle fiber regeneration, thus finding useful application in muscle augmentation.Type: GrantFiled: November 8, 2019Date of Patent: July 19, 2022Assignees: Gachon University of Industry-Academic Cooperation Foundation, Gil Medical CenterInventors: Mee Sup Yoon, Jie Chen, Kook Son, Cheol Soo Choi, Sunghoon Kim, Jung Min Han
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Publication number: 20220219196Abstract: A method of modifying the surface of a coating layer applied to a substrate is disclosed. The surface modification method includes a step (s1) of preparing a substrate by performing pretreatment, a step (s2) of coating the substrate with a coating layer, and a step (s3) of modifying the surface of the coating layer by vibrating the substrate in the vertical direction. The surface modification method does not include a separate chemical process and is thus environmentally friendly and economically advantageous.Type: ApplicationFiled: January 12, 2022Publication date: July 14, 2022Applicant: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Kyoung Su PARK, Dong Su PARK
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Publication number: 20220193202Abstract: The present invention relates to a parathyroid hormone derivative in a dimeric form of a parathyroid hormone fragment and a pharmaceutical composition for the prevention or treatment of bone diseases comprising same. When administered to an animal model, the parathyroid hormone derivative in the dimeric form of the parathyroid hormone according to the present invention significantly increases bone density and enhances osteogenesis and thus can be effectively used for the treatment and prevention of bone diseases.Type: ApplicationFiled: November 7, 2019Publication date: June 23, 2022Applicants: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, GIL MEDICAL CENTERInventor: Sihoon LEE
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Publication number: 20220151539Abstract: A biological classification device and a method for Alzheimer's disease using a brain image are disclosed. The biological classification device includes an image receiving unit which receives a plurality of images obtained by capturing images of a brain of a subject; an image processing unit which acquires neurodegeneration feature related to the brain of the subject and standardized uptake value ratio (SUVR) information from the plurality of images; an image analysis unit which performs first determination of a presence or absence of cranial nerve abnormality based on the neurodegeneration feature(s) and second determination and third determination of a presence or absence of abnormality of beta amyloid protein and tau protein, respectively, based on the SUVR information; and a classifying unit which performs biological classification of the subject related to Alzheimer's disease using the first, the second, and the third determinations together.Type: ApplicationFiled: November 18, 2021Publication date: May 19, 2022Applicants: Heuron Co., Ltd., GIL MEDICAL CENTER, GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Seongbeom Park, Soohwa Song, Young Noh
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Patent number: 11255808Abstract: Disclosed are a chemi-capacitive sensor using a nanomaterial and a method of manufacturing the same. The chemi-capacitive sensor includes a lower electrode including a conductor, an insulation part formed on the lower electrode and including an insulator, an upper electrode disposed on the insulation part and including a first electrode and a second electrode spaced apart from the first electrode, and a detection part disposed on the first electrode, the second electrode, and the insulation part between the first electrode and the second electrode and including at least one selected from the group consisting of a carbon nanomaterial and a metal-oxide-coated carbon nanomaterial. The chemi-capacitive sensor of the present invention is effective at selectively analyzing gas analytes.Type: GrantFiled: July 7, 2020Date of Patent: February 22, 2022Assignee: GACHON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATIONInventors: Jae-Hong Lim, Young Soo Yoon
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Publication number: 20220000868Abstract: The present invention relates to a novel 4-carbonylamino-4-phenylpyrimidine compound or a pharmaceutically acceptable salt thereof. Specifically, the present invention relates to a novel 4-carbonylamino-4-phenylpyrimidine compound or a pharmaceutically acceptable salt thereof, which exhibits GDH activity and as such, is effective for prevention or treatment of obesity, diabetes, or fatty liver.Type: ApplicationFiled: November 26, 2018Publication date: January 6, 2022Applicants: Gachon University Of Industry-Academic Cooperation Foundation, Gil Medical CenterInventors: Dongyun Shin, Cheol Soo Choi, Hee-Sook Jun, Cheol Soon Lee, Seung-Yong Seo, Hojung Choi, Sung Jean Park, Onnuri Bae, Hyunhee Oh, Shi-Young Park
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Publication number: 20210396767Abstract: The present invention relates to a method for predicting the prognosis of ischemic disease using an AGE-RAGE-based biomarker. The biomarker can be used as an indicator factor of the clinical severity of ischemic disease, can maximize the efficiency of stem-cell treatment by determination of the optimal timing of the stem-cell treatment on the basis of changes in the biomarker according to the severity of ischemic disease, and can also be used as a useful indicator factor for verifying efficacy after the stem-cell treatment.Type: ApplicationFiled: October 25, 2019Publication date: December 23, 2021Applicant: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Bonghee LEE, Bayarsaikhan DELGER, Jaesuk LEE
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Patent number: 11184584Abstract: An image decoding method includes: receiving a bitstream that includes video data and signaling data; decoding base layer video data; and decoding at least one enhancement layer video data based on the signaling data and the base layer video data, wherein the video data includes the base layer video data for a base layer and the at least one enhancement layer video data for at least one enhancement layer predicted from the base layer, wherein the signaling data includes region of interest information indicating a region of interest corresponding to a gaze direction of a user in an entire region of a virtual space for video conferencing service.Type: GrantFiled: June 27, 2017Date of Patent: November 23, 2021Assignee: GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventor: Eun-Seok Ryu