Abstract: A technique for forming a film of material (12) from a donor substrate (10). The technique has a step of introducing energetic particles (22) in a selected manner through a surface of a donor substrate (10) to a selected depth (20) underneath the surface, where the particles have a relatively high concentration to define a donor substrate material (12) above the selected depth and the particles for a pattern at the selected depth. An energy source such as pressurized fluid is directed to a selected region of the donor substrate to initiate a controlled cleaving action of the substrate (10) at the selected depth (20), whereupon the cleaving action provides an expanding cleave front to free the donor material from a remaining portion of the donor substrate.

Abstract: Lentiviral vectors modified at the 5' LTR or both the 5' and 3' LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.

Abstract: A method for rerouting calls in a call-routing system having a routing processor storing information about the status of remote telephone stations involves setting a semaphore for station busy at the time a call is routed to the station, and timing the semaphore for a pre-programmed period of time known to be the latency period for returning a real-time signal that the routed call was actually completed. If the signal for call completion is not received in the pre-programmed time, the call is canceled and re-routed by reinserting the call in a routing queue. When the call is canceled the semaphore is reset to indicate the station is not busy. In a preferred embodiment the call is rerouted to the same destination as originally routed.

Abstract: Apparatus and methods are provided for re-routing mis-routed calls in call-routing systems and call-in centers, wherein provision is made for commands to be sent from an agent receiving a mis-routed call to a routing intelligence over a digital network connection, causing a mis-routed call to be inserted in a queue of calls to be routed ahead of calls received to be routed after the first call was mis-routed. In some embodiments the first agent may simply send back the mis-routed call to be requeued. In other instances the agent may confer with a second agent at a station to which the call is to be forwarded, before the caller is connected to the second agent. In still other instances the first agent, the second agent, and the caller may be conferenced together.

Abstract: An automated dialer for a call center maximizes agent efficiency in two different ways. In a first method overdial probability is expressed as a probability function of number of agents and total traffic volume; the probability function is set equal to a maximum allowable overdial probability; and the resulting equation is solved for maximum total traffic volume producing the maximum overdial probability. The maximum total traffic volume is then used to determine a new dialing rate by dividing the difference between the calculated maximum traffic volume and known inbound traffic volume by the product of average call length and hit rate, where hit rate is the percentage of connected calls to total dialed outbound calls. In a second method a maximum total traffic volume is calculated from total number of agents times a desired agent utilization factor, and the total traffic volume is used as in the first method to calculate and set a new dialing rate for outbound calls.

Abstract: A system (33) for outbound dialing for call centers (11) place an outbound dialer (21) at network level (13), and client call centers provide destination number calling lists. The outbound dialer (21), upon completing a call to a destination number, connects the completed call to a routing point at a client call center. The system (33) may be CTI-enhanced, and can be hosted by a client of a network provider, or by the network provider. Clients may subscribe to the network provider for service, providing calling lists and routing points, and completed calls may be routed to call centers operated by different clients. The architecture and method of the system (33) minimizes the number of leased lines required by each call center taking advantage of the system (33).

Abstract: A method for rerouting calls in a call-routing system having a routing processor storing information about the status of remote telephone stations involves setting a semaphore for station busy at the time a call is routed to the station, and timing the semaphore for a pre-programmed period of time known to be the latency period for returning a real-time signal that the routed call was actually completed. If the signal for call completion is not received in the pre-programmed time, the call is canceled and re-routed by reinserting the call in a routing queue. When the call is canceled the semaphore is reset to indicate the station is not busy. In a preferred embodiment the call is rerouted to the same destination as originally routed.

Abstract: A method of generating an upsampled target pixel positioned between two lines of input source data includes the step of comparing pixels of different lines of the source data in a region surrounding the upsampled target pixel to be generated in at least two different directions. An interpolation direction based on the comparison is selected and interpolations between selected pixels of the source data in the determined interpolation direction are carried out to compute intermediate pixels on a line segment passing through the upsampled target pixel. An interpolation between the intermediate pixels is carried out to generate the upsampled target pixel. An apparatus for performing the method is also disclosed.

Abstract: A technique for forming a film of material (12) from a donor substrate (10). The technique has a step of introducing energetic particles (22) in a selected manner through a surface of a donor substrate (10) to a selected depth (20) underneath the surface, where the particles have a relatively high concentration to define a donor substrate material (12) above the selected depth and the particles for a pattern at the selected depth. An energy source is directed to a selected region of the donor substrate to initiate a controlled cleaving action of the substrate (10) at the selected depth (20), whereupon the cleaving action provides an expanding cleave front to free the donor material from a remaining portion of the donor substrate.

Abstract: The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate or delipidated M. vaccae cells are also provided.

Abstract: Methods and compositions are provided for expression of mammalian genes in culture. An amplifiable gene is introduced by homologous recombination in juxtaposition to a target gene, the resulting combination of amplifiable gene and target gene transferred to a convenient host and the target gene amplified by means of the amplifiable gene. The resulting expression host may then be grown in culture with enhanced expression of the target gene.

Abstract: Methods for the treatment of skin disorders, including psoriasis, atopic dermatitis, allergic contact dermatitis, alopecia areata and skin cancers are provided, such methods comprising administering multiple doses of a composition having antigenic and/or adjuvant properties. Compositions which may be usefully employed in the inventive methods include inactivated M. vaccae cells, delipidated and deglycolipidated M. vaccae cells, M. vaccae culture filtrate and compounds present in or derived therefrom, together with combinations of such compositions.

Abstract: A system for routing Internet Protocol Network Telephony (IPNT) calls has a default router connected to a wide area network (WAN) for receiving and routing the calls, the default router having a set of default routing rules, and an intelligent router coupled to the default router. The default router, upon receiving a call, requests routing from the intelligent router, and routes by a returned instruction within a predetermined time. If there is no returned instruction in the predetermined time, the default router routes the call by the default routing rules. In a preferred embodiment the intelligent router is a router performing for a particular organization, such as a commercial entity, and may have access to a company database. In some embodiments routing destinations are call centers on premises of the particular organization or company, and the call centers may each be managed by a managing processor connected to the WAN, which may be the Internet.

Abstract: Apparatus and methods are provided for re-routing mis-routed calls in call-routing systems and call-in centers wherein provision is made for commands to be sent from an agent receiving a mis-routed call to a routing intelligence over a digital network connection, causing a mis-routed call to be inserted in a queue of calls to be routed ahead of calls received to be routed after the first call was mis-routed. In some embodiments the first agent may simply send back the mis-routed call to be requeued. In other instances the agent may confer with a second agent at a station to which the call is to be forwarded, before the caller is connected to the second agent. In still other instances the first agent, the second agent, and the caller may be conferenced together.

Abstract: A call center system supports remote agent stations through a network by establishing a data link between a computer platform at the remote agent station and a CTI-processor connected to a telephony switch at the call center, and switching incoming calls from the call center to a telephone at the remote agent station while sending data pertaining to the calls via the data link to the computer platform at the remote agent station to be displayed. Data pertaining to calls is retrieved from a data base at the call center and sent via the data link to be displayed on a video display at the remote agent station. The data can include scripts for an agent at the remote station. Call center services are supported by cooperation between software at the CTI processor and the computer platform at the remote station. In one embodiment the data link, once established, is kept open while calls continue to be switched to the remote station.

Abstract: An interactive directory provided for a workstation having a connected video monitor and adapted for network access has an interactive display for displaying status for individual entities, being persons and organizations. Entities are listed in the display along with status for each entity. There may be multiple fields for status, and some fields display telephone numbers, while others may provide alphanumeric display. A remote access contact address is stored and associated with each directory entity, and when the directory is active, the workstation accesses status information from network sources associated with individual directory listings. Status for entities in the directory is therefore updated in real time as the directory is used. In some embodiments multiple graphic indicia, such as underlining, shading, font choice and the like are used to provided status indication in various fields of the interactive display. In some embodiments alpha-numeric status is provided as well.

Abstract: Novel isolated DNA sequences associated with the lignin biosynthetic pathway are provided, together with DNA constructs including such sequences. Methods for the modulation of lignin content in plants are also disclosed, the methods comprising incorporating one or more of the inventive DNA sequences or a sequence complementary to an inventive DNA sequence into the genome of a plant.

Abstract: A telephone call-routing system comprises a routing intelligence adapted to receive real-time activity reports on busy status of remote telephone stations, and to route incoming calls based on the busy status. In a preferred embodiment the routing intelligence sets a busy semaphore for each station to which a call is routed at the time the call is routed, before a real-time signal is returned that the station is in fact busy. The semaphore is initially set to busy for a first period of time substantially equal to the known latency for returning the real-time busy signal. After the first period of time, and with return of a real-time busy signal, the semaphore is reset to busy for a second period of time substantially equal to the historical average elapsed time for calls in the call-routing system, after which the semaphore is released. After the first period of time, and in the absence of the real-time busy signal, the semaphore is immediately released so further calls may be routed to the station.

Abstract: In an Internet Protocol Network Telephony (IPNT) call-routing system, a call-routing processor connected to a wide area network (WAN) for receiving and forwarding calls is adapted to receive IPNT calls and to route them to remote computer stations based on information available at the routing processor. Remote stations are adapted in a manner that enables an agent at a remote station, upon determining that a call has been mis-routed for any reason, to return the call to the routing processor, which is adapted for re-routing the call based on the fact of return. In some cases the agent who originally receives the call may elicit further information from the caller, and send the new information back to the router with the call. The router in this instance uses the new information in re-routing. Calls may be re-routed cold, by allowing the first agent to talk to the second before the call is connected to the second, or by conferencing the first agent, the second agent, and the caller.

Abstract: A computerized telephony call center for serving a customer base has a central switch connected to a plurality of telephones at operator workstations and adapted to route calls to individual ones of the telephones, and also connected to a public switched telephone network, and a first processor connected to the central switch by a high-speed data link and to the telephone network by a digital network connection. The first processor is adapted to monitor transactional activity of the central switch, to process the activity information according to selected routines in the processor, and to communicate processed information to a second processor over the digital network connection. The digital network connection may be a TCP.backslash.IP connection. In a preferred embodiment first processor is connected by a local area network (LAN) to network interfaces including a video display unit (VDU) and input apparatus proximate individual ones of the plurality of telephones connected to the central switch.