Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using N-Oxides of heterocyclic esters, amides, thioesters, or ketones
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
June 4, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using an N-oxide of a heterocyclic ester, amide, thioester, or ketone.
Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using small molecule carbamates and ureas.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
May 28, 2002
Assignee:
GPI Nil Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic thioesters and ketones.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
May 7, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to neurotrophic low molecular weight, small molecule N-linked sulfonamides of heterocyclic thioesters having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
Type:
Application
Filed:
August 10, 2001
Publication date:
April 25, 2002
Applicant:
GPI NIL HOLDINGS, INC.
Inventors:
Gregory S. Hamilton, Jai-He Li, Wei Huang
Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using pipecolic acid derivatives.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
April 23, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked ureas or carbamates of heterocyclic thioesters.
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using small molecule carbamates and ureas.
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic thioesters and ketones.
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using N-linked sulfonamides of heterocyclic thioesters.
Abstract: This invention relates to novel compositions and uses of a N-linked sulfonamide of an N-heterocylic carboxylic acid or isostere thereof for treating a vision disorder or improving vision or treating memory impairment or enhancing memory performance in an animal.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
January 15, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to novel compositions and uses of carboxylic acid or isostere of a heterocyclic ring compound having two or more heteroatoms within the heterocyclic ring and wherein the heterocyclic ring has at least one substituent attached thereto, the substituent selected from the group consisting of a diketo, a sulfonamide, a urea, a carbamate, and substituted derivatives thereof for treating a vision disorder or improving vision or treating memory impairment or enhancing memory performance in an animal.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
January 8, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance in an animal, using pipecolic acid derivatives.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
January 1, 2002
Assignee:
GPI NIL Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to neurotrophic, low molecular weight, small molecule heterocyclic ketone and thioester compounds, compositions containing the same, and the use of such compounds for treating neurological disorders, including physically damaged nerves and neurodegenerative diseases.
Abstract: This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance in an animal using small molecule sulfonamides.
Type:
Grant
Filed:
August 14, 1998
Date of Patent:
December 25, 2001
Assignee:
Gpi Nil Holdings, Inc.
Inventors:
Douglas T. Ross, Hansjörg Sauer, Gregory S. Hamilton, Joseph P. Steiner
Abstract: This invention relates to novel N-heteorocyclic carboxylic acids and carboxylic acid isosteres, their preparation and use for treating neurological disorders including physically damaged nerves and neurodengenerative diseases, for treating alopecia and promoting hair growth, for treating vision disorders and/or improving vision, and for treating memory impairment and/or enhancing memory performance by administering such compounds.
Type:
Grant
Filed:
December 2, 1999
Date of Patent:
December 18, 2001
Assignee:
GPI Nil Holdings, Inc.
Inventors:
Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using heterocyclic esters or amides.
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
Abstract: This invention relates to pharmaceutical compositions and methods for treating alopecia and promoting hair growth using pipecolic acid derivatives.
Abstract: This invention relates to methods of treating hair loss, through hair revitalization and germination, by administering non-immunosuppresive pyrrolidine carboxylate compounds.