Patents Assigned to GRÜNENTHAL GMBH
  • Mixed ORL1/mu-agonists for the treatment of pain
    Publication number: 20080125475
    Abstract: The invention relates to the use of compounds which exhibit an affinity for the ?-opioid receptor of at least 100 nM (Ki value, human) and an affinity for the ORL-1 receptor, wherein the ratio between the affinities ORL1/? defined as 1/[Ki(ORL1)/Ki(?)] is from 0.1 to 30, for the treatment of pain.
    Type: Application
    Filed: September 28, 2007
    Publication date: May 29, 2008
    Applicant: GRUNENTHAL GMBH
    Inventors: KLAUS LINZ, Babette-Yvonne Kogel, Wolfgang Schroder, Thomas Christoph, Jean De Vry, Elmar Friderichs