Patents Assigned to Hamilton Bonaduz AG
  • Publication number: 20200360916
    Abstract: The present invention relates to a pipette device with a pipette channel which extends along a channel axis defining an axial direction and which passes through a channel component arrangement which, at a coupling longitudinal end, has a coupling configuration for the releasable coupling of a pipette tip. The coupling configuration has a locking component with a radially outwardly facing engagement surface arrangement, which is movable between a locking position more radially remote from the channel axis and an unlocking position lying radially closer to the channel axis. The coupling configuration has a sealing component separate from the locking component, and that the actuator drive has a switchable magnetic field source and a reaction component which is movable by the locally changing magnetic field thereof and which is connected to the locking actuator in such a way as to transmit movement.
    Type: Application
    Filed: November 8, 2018
    Publication date: November 19, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Silvio Walpen, Fridolin Gysel
  • Patent number: 10837979
    Abstract: A pipetting apparatus (10) having a guidance frame (12) having a first linear guidance rail (52) and having a second linear guidance rail (56), the first and the second linear guidance rail (52, 56) proceeding parallel to one another along a displacement axis (VL) and being provided at a distance from one another orthogonally to the displacement axis (VL), and having a pipetting channel (14) which extends along a channel axis (K14) that is nonparallel, preferably orthogonal, to the displacement axis (VL) and which is guided displaceably along the displacement axis (VL) with a first bearing component (54) on the first linear guidance rail (52) and with a second bearing component (58) on the second linear guidance rail (56), is characterized in that the first and the second bearing component (54, 58) are arranged with a spacing (A) from one another along the displacement axis (VL).
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: November 17, 2020
    Assignee: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen
  • Publication number: 20200298242
    Abstract: A pipetting device includes pipetting unit(s), a guide assembly with at least one guide rail on which the pipetting unit(s) is guided in order to be moved along a movement axis, and a linear drive assembly, by which the pipetting unit(s) can be driven in order to be moved along the movement axis. The linear drive device has a stationary stator, and the at least one pipetting unit forms a linear drive assembly rotor which can be moved along the movement axis relative to the stator. The pipetting device also has at least two rotor magnet assemblies which interact with the same common stator magnet assembly so as to generate a drive force and which are arranged at a distance from one another along a spacing axis that is orthogonal to the movement axis. The common stator magnet assembly is located between the at least two rotor magnet assemblies.
    Type: Application
    Filed: November 19, 2018
    Publication date: September 24, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen, Fridolin Gysel
  • Publication number: 20200282390
    Abstract: The present invention relates to a pipetting apparatus for aspirating and dispensing metered liquids, encompassing: at least one guidance tube (30) extending along a cylinder axis (Z), the cylinder axis (Z) defining: an axial direction proceeding along its direction of extent; a radial direction proceeding orthogonally thereto; and a circumferential direction extending therearound; a piston (10) received in the guidance tube (30) axially movably relative thereto; a coupling configuration embodied for temporary or permanent coupling of a pipetting tip; and a drive apparatus (32) for driving the piston (10) to move axially relative to the guidance tube (30), the guidance tube (30) comprising a coupling-side longitudinal end (48) that is located closer to the coupling configuration; and comprising a servicing-side longitudinal end (50) that is located oppositely from the coupling-side longitudinal end (48) and is located farther from the coupling configuration; the piston (10) encompassing at least one pe
    Type: Application
    Filed: October 11, 2017
    Publication date: September 10, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Heidi Cattaneo
  • Publication number: 20200278371
    Abstract: A pipetting apparatus (10) having a guidance frame (12) having a first linear guidance rail (52) and having a second linear guidance rail (56), the first and the second linear guidance rail (52, 56) proceeding parallel to one another along a displacement axis (VL) and being provided at a distance from one another orthogonally to the displacement axis (VL), and having a pipetting channel (14) which extends along a channel axis (K14) that is nonparallel, preferably orthogonal, to the displacement axis (VL) and which is guided displaceably along the displacement axis (VL) with a first bearing component (54) on the first linear guidance rail (52) and with a second bearing component (58) on the second linear guidance rail (56), is characterized in that the first and the second bearing component (54, 58) are arranged with a spacing (A) from one another along the displacement axis (VL).
    Type: Application
    Filed: July 3, 2017
    Publication date: September 3, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen
  • Patent number: 10684301
    Abstract: The invention relates to a sample processing system and method for processing biological samples, comprising a sample processing device having: a receiving plate, which is arranged substantially horizontally in a plane; a first and second working arm, which can move relative to the receiving plate and extend substantially parallel to each other in a second direction (Y) over the receiving plate; at least one pipetting device mounted on the first working arm, which is movable in the second direction (Y) and in a third direction (Z) orthogonal in relation to the first and second direction (X, Y); at least one gripping device, mounted on the second working arm, with grippers that can be rotated around a gripper axis of rotation (GA) parallel to the third direction (Z); and a control device for controlling the pipetting device and the gripping device.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: June 16, 2020
    Assignee: Hamilton Bonaduz AG
    Inventor: Nando Giovanoli
  • Publication number: 20200139379
    Abstract: A magnetic isolating apparatus (10) for isolating magnetic particles (66) from a suspension has an immersion section (30) which is designed to be temporarily immersed in the suspension, a guide apparatus (16) which extends along a guide path (F), a magnet arrangement (18) which is guided by the guide apparatus (16) such that it can be moved between an active position which is situated close to the immersion section (30) and an inactive position which is positioned further away from the immersion section (30) along the guide path (F), so that a magnetic field in the region of the immersion section (30) can be changed by moving the magnet arrangement (18) between the active position and the inactive position, and a drive apparatus (22, 50) by which the magnet arrangement (18) can be driven to move at least in a direction between the active position and the inactive position, wherein the drive apparatus (22, 50) is coupled in a non-physical manner to the magnet arrangement (18) by a force field and/or a fluid so
    Type: Application
    Filed: September 25, 2017
    Publication date: May 7, 2020
    Applicant: Hamilton Bonaduz AG
    Inventors: Ingo Schwaiger, Hanspeter Romer
  • Patent number: 10632460
    Abstract: A pipetting device has a pipetting channel extending along a channel path, in which a piston is accommodated to be movable along the channel path to change the pressure of a working gas that wets the piston on a dosing side facing the dosing liquid. The pipetting device includes a movement drive for driving the piston along the channel path and a control unit configured to operate the movement drive for pipetting a predetermined single dosing volume of less than 5 ?l with the piston moving in the pipetting direction and its dosing side end face sweeping over a pipetting volume which is not less than 1.4 times greater than the single dosing volume, and subsequently moving in a counter pipetting direction and its dosing side end face sweeping over a counter pipetting volume, wherein not more than 50 ms elapse between beginning control signals.
    Type: Grant
    Filed: July 26, 2016
    Date of Patent: April 28, 2020
    Assignee: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Fridolin Gysel, Urs Lendenmann
  • Publication number: 20200072738
    Abstract: A sensor arrangement (50) encompasses a reaction subassembly (72) having a housing (52) and having a detector subassembly (54), there being provided in the housing (52) a layered component arrangement (60) that encompasses: a luminophore-containing reaction laminate (62) that is excitable, by irradiation with a first electromagnetic radiation of a first wavelength, to emit a second electromagnetic radiation of a second wavelength different from the first wavelength; and a temperature-detection laminate (64) emitting an infrared radiation; the housing (52) comprising an opening (78a, 78b) through which a fluid is introducible; the housing (52) comprising a reaction window (66a) and a temperature-sensing window (66b) arranged physically remotely therefrom; the one reaction window (66a) transmitting the first (E1) and the second electromagnetic radiation (E2); and the temperature-sensing window (66b) being penetrable by infrared radiation (I); the detector subassembly (54) encompassing: a radiation source (
    Type: Application
    Filed: March 6, 2018
    Publication date: March 5, 2020
    Applicants: Hamilton Medical AG, Hamilton Bonaduz AG
    Inventors: Marco Giardina, Bernd Offenbeck, Christoph Schranz, Thomas Laubscher, Dominik Novotni, Dirk Schönfuss
  • Patent number: 10550360
    Abstract: A fluid supply interface includes a line component having a first coupling formation for the temporary coupling of a first fluid channel, a second coupling formation for the temporary coupling of a second fluid channel, and a third coupling formation for the temporary or permanent coupling of a third fluid channel, each of said coupling formations being penetrated by a fluid line section, wherein in the line component, a fluid line assembly is formed, by means of which each fluid line section of the first, second and third coupling formations is or can be connected to each fluid line section of the other two coupling formations for the purpose of fluid transport.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: February 4, 2020
    Assignee: Hamilton Bonaduz AG
    Inventors: Jens Grosch, Tom Kissling, Thomas Zumstein
  • Publication number: 20200032195
    Abstract: A fluid supply interface includes at least one supply coupling configuration, at least one discharge coupling configuration, at least one user coupling configuration, and a fluid conduit that connects the supply, discharge, and user coupling configurations to one another. A supply valve is capable of having fluid flow through it or is blocked for flow through it. A discharge valve is capable of having fluid flow through it or is blocked for flow through it. The supply valve is preloaded into a blocking position that prevents flow, and opens by means of a sufficiently large pressure difference between the two sides of the supply valve, against the preload force, for flow through in a direction from the supply coupling configuration toward the fluid conduit. The discharge valve likewise being preloaded into a closed position that prevents flow through it.
    Type: Application
    Filed: June 14, 2017
    Publication date: January 30, 2020
    Applicant: Hamilton Bonaduz AG
    Inventor: Oliver Kühne
  • Patent number: 10520483
    Abstract: An autonomous device for detecting characteristics of a medium to be measured is disclosed. The device includes a sensor, a first microcontroller and a second microcontroller. The first microcontroller has a memory which is not resistant against gamma radiation during the sterilization of the device and the second microcontroller has a memory which is resistant against gamma radiation during the sterilization of the device.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: December 31, 2019
    Assignee: Hamilton Bonaduz AG
    Inventors: Frederic Juillerat, Yoann Gasteuil
  • Publication number: 20190358626
    Abstract: A pipetting apparatus and method for pulsed dispensing of small metered-liquid doses of no more than 1 ?l. The apparatus includes a pipetting conduit at least partly filled with working gas, a pressure-modifying apparatus for modifying the pressure of the working gas, and a control apparatus for applying control to the pressure-modifying apparatus. The control apparatus can control the pressure-modifying apparatus so as to generate in the pipetting conduit, with respect to a reference holding pressure in the pipetting conduit which is necessary for immovable holding of the metered-liquid quantity, an overpressure pulse having a pulse duration of no more than 40 ms.
    Type: Application
    Filed: December 11, 2017
    Publication date: November 28, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Jürg Rast, Jonas Hilti
  • Patent number: 10478990
    Abstract: A punching device for processing samples applied to a sample card is provided. The punching device includes a movable gripper unit and an image capturing device and at least one punching head having a punch and a lower die. The punching head has a receiving opening into which a sample card is introducible by means of the movable gripper unit and is positionable relative to the punching head. The punching device further includes a punching drive which is couplable or coupled to the punch of the punching head. The punching device further includes a receiving plate supporting the receiving container and having a light source illuminating at least a part of the receiving plate. The light source is arranged such that at least a part of the receiving container located on the receiving plate can be illuminated from the direction of the receiving plate.
    Type: Grant
    Filed: April 29, 2012
    Date of Patent: November 19, 2019
    Assignee: Hamilton Bonaduz AG
    Inventors: Nando Giovanoli, Reto Menzi
  • Patent number: 10465156
    Abstract: A cap for cell culture container enclosing a culture volume and having an opening, comprising a valve arrangement, suitable for filling of the cell culture container with a fluid and/or for pumping fluid out from the cell culture container, and a compensation opening suitable for aerating the cell culture container and/or for pressure compensation during filling and pumping out, said valve arrangement being designed to be switchable between an outlet position and a blocking position, to be connectable to a fluid supply interface, and to be switchable without contact.
    Type: Grant
    Filed: October 29, 2014
    Date of Patent: November 5, 2019
    Assignee: Hamilton Bonaduz AG
    Inventors: Thomas Jaeger, Carsten Etzold, Rene Demarmels
  • Patent number: 10435660
    Abstract: A fluid line element for building a fluid line section comprising a plurality of identical fluid line elements, wherein the fluid line element comprises: —an element body, —a first throughflow opening provided on the element body and a second throughflow opening, different from the first, —and a flow channel provided in the element body, which fluidically connects the first and the second throughflow openings for throughflow along a channel path. In a first region of the fluid line element, located closer to the first than to the second throughflow opening, a throughflow body formed separately from the element body is provided, which —forms a part of the flow channel, —is formed from a material having a lower elasticity modulus than the material of the element body, and —on the longitudinal end thereof facing into the interior of the element body, comprises a valve seat formation surrounding the channel path.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: October 8, 2019
    Assignee: Hamilton Bonaduz AG
    Inventors: Tobias Seiler, Oliver Kühne, Carsten Etzold
  • Patent number: 10421073
    Abstract: The invention relates to a covering device (10), in particular a lid, for covering reaction vessels (50), in particular PCR plates, microtiter plates, and the like, comprising: a substantially flat main body (14) having an inside (34) and an outside (12), at least one planar sealing element (36) arranged on the main body (14) and connected to the main body, wherein the at least one sealing element (36) is arranged on the inside (34) of the main body (14), an edge segment (16), which runs along the periphery of the main body and extends from the outside (12) in the direction of the inside (34) and beyond the inside, and at least one spring element (22, 24) arranged on the main body (14) or on the sealing element (36), which at least one spring element is designed in such a way that the at least one spring element supports the covering device (10) on a surface (54) of a reaction vessel (50) to be covered facing the covering device (10) in the relaxed state of the at least one spring element and that an intermed
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: September 24, 2019
    Assignee: HAMILTON BONADUZ AG
    Inventors: Eduard Woizenko, Sandro Sferlazza
  • Publication number: 20190257850
    Abstract: A pipetting apparatus (10) having a guidance frame (12) having a first linear guidance rail (52) and having a second linear guidance rail (56), the first and the second linear guidance rail (52, 56) proceeding parallel to one another along a displacement axis (VL) and being provided at a distance from one another orthogonally to the displacement axis (VL), and having a pipetting channel (14) which extends along a channel axis (K14) that is nonparallel, preferably orthogonal, to the displacement axis (VL) and which is guided displaceably along the displacement axis (VL) with a first bearing component (54) on the first linear guidance rail (52) and with a second bearing component (58) on the second linear guidance rail (56), is characterized in that the first and the second bearing component (54, 58) are arranged with a spacing (A) from one another along the displacement axis (VL).
    Type: Application
    Filed: July 3, 2017
    Publication date: August 22, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Silvio Walpen
  • Publication number: 20190255522
    Abstract: The present invention relates to a pipetting apparatus for aspirating and dispensing metered liquids, encompassing: at least one guidance tube (30) extending along a cylinder axis (Z), the cylinder axis (Z) defining: an axial direction proceeding along its direction of extent; a radial direction proceeding orthogonally thereto; and a circumferential direction extending therearound; a piston (10) received in the guidance tube (30) axially movably relative thereto; a coupling configuration embodied for temporary or permanent coupling of a pipetting tip; and a drive apparatus (32) for driving the piston (10) to move axially relative to the guidance tube (30), the guidance tube (30) comprising a coupling-side longitudinal end (48) that is located closer to the coupling configuration; and comprising a servicing-side longitudinal end (50) that is located oppositely from the coupling-side longitudinal end (48) and is located farther from the coupling configuration; the piston (10) encompassing at least one pe
    Type: Application
    Filed: October 11, 2017
    Publication date: August 22, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hanspeter Romer, Reto Ettinger, Fridolin Gysel, Heidi Cattaneo
  • Publication number: 20190247844
    Abstract: A permanent-magnet piston subassembly (10) for a pipetting apparatus, the piston subassembly (10) extending along a piston axis (K) and comprising a plurality of permanent-magnet arrangements (14a to 14m) that are arranged one behind another along the piston axis (K) with alternatingly opposite polarization directions in such a way that for each two permanent-magnet arrangements (14i, 14j) directly successive along the piston axis, it is the case that magnetic poles located closest to one another along the piston axis (K), of different successive permanent-magnetic arrangements (14a to 14m), are like poles, is characterized in that the piston subassembly (10) encompasses a sheath tube (12), extending along the piston axis (K) constituting a tube axis (H), in which the plurality of permanent-magnet arrangements (14a to 14m) are received.
    Type: Application
    Filed: October 11, 2017
    Publication date: August 15, 2019
    Applicant: Hamilton Bonaduz AG
    Inventors: Hans-Peter Romer, Heidi Cattaneo