Patents Assigned to Health & Science, LLC
  • Patent number: 8696038
    Abstract: A fitting assembly is provided having a nut and a ferrule, which in certain embodiments may be assembled by an operator. The nut and ferrule of the fitting assembly have passageways therethrough for receiving and removably holding tubing. The nut and ferrule fitting assembly may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: April 15, 2014
    Assignee: IDEX Health & Science LLC
    Inventor: Nathaniel Nienhuis
  • Patent number: 8689824
    Abstract: A check valve construction is provided having: a movable disc with a flat surface on a first side and a convex shaped surface on the opposing side, a first seat on for the flat surface and a second seat for the convex surface, where the narrowest portion of the fluid path is defined by the equation: G 3 = 12 ? ? ? ? W ? ? Q ? ? ? D ? ? ? ? ? P Wherein G: the gap of most narrow passageway between the flat surface of the disc and disc seat; ?: dynamic viscosity of the fluid; D: mean diameter of the flat sealing surface of the disc; Q: desired fluid flow rate; W: breadth of the flat sealing surface of the disc; ?P: pressure differential across the gap (G).
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: April 8, 2014
    Assignee: IDEX Health & Science, LLC
    Inventor: Zhenxing Dong
  • Publication number: 20140090250
    Abstract: A multi-position valve assembly including a valve housing, a stator element and a rotor element rotatably mounted about a rotational axis. The valve assembly further includes a pressure adjustment assembly movable between a release position and a stop position, hard stopped relative to the valve housing. The pressure adjustment assembly includes a pressure adjuster device configured to movably cooperate between the rotor element and the valve housing to adjustably generate an axial compression pressure at the rotor-stator interface at a calibrated operating pressure, PC. When the pressure adjustment assembly is oriented in the release position, the axial compression pressure is substantially removed from the rotor-stator interface. In contrast, when the pressure adjustment assembly is oriented in the stop position, the axial compression pressure is substantially reproduced at the calibrated operating pressure, PC.
    Type: Application
    Filed: December 5, 2013
    Publication date: April 3, 2014
    Applicant: IDEX Health & Science LLC
    Inventors: Christopher R. TOWER, Mark J. GREEN
  • Patent number: 8668763
    Abstract: A liquid degassing apparatus is arranged to prevent pervaporated solvent cross-contamination by counteracting liquid vapor pervaporation flow. Liquid vapor pervaporation cross-contamination among a plurality of degassing modules is counteracted with specifically configured volumes and bleed inlet flow to conduits fluidly coupling permeate sides of said plurality of degassing chambers.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: March 11, 2014
    Assignee: IDEX Health & Science LLC
    Inventor: Yuri Gerner
  • Publication number: 20140026647
    Abstract: A fitting assembly having a nut, a ferrule, and a ferrule tip that may be assembled by an operator. The fitting assembly includes a nut with first and second ends, with the second end adapted to receive the first end of a ferrule, and a ferrule tip with a first end having an externally tapered portion adapted to abut the second end of the ferrule and a second end adapted to be received in a component or fitting of a liquid chromatography system. The nut, ferrule and ferrule tip of the fitting assembly have passageways therethrough for receiving and removably holding tubing.
    Type: Application
    Filed: September 26, 2013
    Publication date: January 30, 2014
    Applicant: IDEX Health & Science LLC
    Inventors: Scott J. Ellis, Eric Beemer, Nathaniel Nienhuis, Craig W. Graham, Troy N. Sanders
  • Patent number: 8627851
    Abstract: A multi-position valve assembly including a valve housing, a stator element and a rotor element rotatably mounted about a rotational axis. The valve assembly further includes a pressure adjustment assembly movable between a release position and a stop position, hard stopped relative to the valve housing. The pressure adjustment assembly includes a pressure adjuster device configured to movably cooperate between the rotor element and the valve housing to adjustably generate an axial compression pressure at the rotor-stator interface at a calibrated operating pressure, PC. When the pressure adjustment assembly is oriented in the release position, the axial compression pressure is substantially removed from the rotor-stator interface. In contrast, when the pressure adjustment assembly is oriented in the stop position, the axial compression pressure is substantially reproduced at the calibrated operating pressure, PC.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: January 14, 2014
    Assignee: Idex Health & Science LLC
    Inventors: Christopher R. Tower, Mark J. Green
  • Patent number: 8622086
    Abstract: A micro-fluidic valve system is provided which includes a micro-fluidic valve actuator apparatus, a fluid distribution manifold and a micro-fluidic POD apparatus. The POD apparatus includes a POD housing that defines an interior central passage extending from a distal mounting end of the housing to a proximal portion thereof. The POD apparatus further includes a stator device disposed in the interior central passage, and includes a distal stator face that cooperates with an opening in the distal mounting end to define a gasket receptacle. A relatively thin, elastomeric gasket member is disposed in the gasket receptacle of the housing in abutting contact between the stator and a communication face of the manifold. A fluid-tight seal is then formed between each respective stator communication port of the stator device and a corresponding manifold communication port of the manifold.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: January 7, 2014
    Assignee: Idex Health & Science LLC
    Inventor: Carl M. Servin
  • Patent number: 8569070
    Abstract: A fitting assembly having a nut, a ferrule, and a ferrule tip that may be assembled by an operator. The fitting assembly includes a nut with first and second ends, with the second end adapted to receive the first end of a ferrule, and a ferrule tip with a first end having an externally tapered portion adapted to abut the second end of the ferrule and a second end adapted to be received in a component or fitting of a liquid chromatography system. The nut, ferrule and ferrule tip of the fitting assembly have passageways therethrough for receiving and removably holding tubing.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 29, 2013
    Assignee: IDEX Health & Science LLC
    Inventors: Scott J. Ellis, Eric Beemer, Nathaniel Nienhuis, Craig W. Graham, Troy N. Sanders
  • Publication number: 20130233053
    Abstract: A torque limited fitting is provided having a head and a body, which in certain embodiments may be assembled by an operator. The body of the torque limited fitting has a passageway therethrough for receiving and removably holding tubing. The torque limited fitting may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.
    Type: Application
    Filed: November 2, 2012
    Publication date: September 12, 2013
    Applicant: IDEX Health & Science LLC
    Inventors: Eric Beemer, Craig Graham, Mark Hahn
  • Publication number: 20130234432
    Abstract: A microfluidic interconnect system and method for assembly thereof is described. The microfluidic interconnect has a port and a seal, with the port having a reverse taper. The port has a first port end, a second port end, and an inner port surface with a tapered portion. Each port end has an opening with a diameter, and in certain embodiments, the diameter of the first port end is smaller than the diameter of the second port end. The seal has a first end and a second end, and each seal end has a rim and an opening with an inner diameter and an outer diameter. The seal also has an inner surface and an outer surface, where in certain embodiments, each surface has a tapered portion.
    Type: Application
    Filed: November 27, 2012
    Publication date: September 12, 2013
    Applicant: IDEX Health & Science LLC
    Inventor: Craig Graham
  • Patent number: 8528592
    Abstract: A check valve construction is provided in which a moveable a movable ball having a convex surface resides in a cage having a conical frustum chamber and a seat for the ball. A fluid path between the ball and the cage is defined by the equation: G = D ? ? cos ? ( b - a ) 2 ? ? cos ? ? b - d 2 wherein G is the gap of the narrowest passageway of the fluid path, D is the diameter of the small end of the conical frustum chamber of the cage, d is the diameter of the convex surface of the ball, a is the angle between a vertical diameter of the ball and the position of the narrowest gap on the convex surface of the ball, and, b is the angle between the vertical diameter of the movable element and the position of the small end of conical frustum chamber of the cage.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: September 10, 2013
    Assignee: Idex Health & Science, LLC
    Inventor: Zhenxing Dong
  • Publication number: 20130227831
    Abstract: A fitting assembly is provided having a nut and a ferrule, which in certain embodiments may be assembled by an operator. The nut and ferrule of the fitting assembly have passageways therethrough for receiving and removably holding tubing. The nut and ferrule fitting assembly may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 5, 2013
    Applicant: IDEX Health & Science LLC
    Inventor: Nathaniel Nienhuis
  • Publication number: 20130196001
    Abstract: Presented are salt replacement compositions and methods which are useful for replacing dietary sodium and for preventing and treating diseases associated with sodium overconsumption, including diabetes-Type 2.
    Type: Application
    Filed: January 23, 2013
    Publication date: August 1, 2013
    Applicant: Health & Science, LLC
    Inventor: Health & Science, LLC
  • Patent number: 8440003
    Abstract: A liquid degassing apparatus is arranged to limit pervaporation through a membrane by attenuating pressure oscillations developed by a vacuum pump. The attenuation is obtained through a combination of one or more flow restrictors and added volume chambers fluidly interposed between the degassing chamber and the vacuum pump. The pressure oscillation attenuation may further inhibit cross-contamination of pervaporated solvents among a plurality of distinct degassing chambers.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: May 14, 2013
    Assignee: IDEX Health & Science, LLC
    Inventors: Yuri Gerner, Quan Liu, Carl W. Sims
  • Patent number: 8431020
    Abstract: A liquid dispensing system is provided for automated dispensing of a plurality of liquid reagents into a recreational body of water. The liquid dispensing system includes a cartridge apparatus housing a plurality of liquid reagent containers, each containing a respective liquid reagent. A docking assembly is provided having a dock manifold device, and is releasably coupled to the cartridge apparatus between a first condition and a second condition. In a first condition, the cartridge apparatus can be removably coupled to the docking assembly, while in the second condition, the cartridge apparatus is lockably mounted to the docking assembly in a manner permitting fluid communication from the respective reagent container to respective fluid passages of the manifold device. The dispensing system further includes a dosing engine having a valve manifold device to selectively dispense the liquid reagents into the recreational body of water through a dispensing port.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: April 30, 2013
    Assignee: Idex Health & Science LLC
    Inventors: Michael R. Straka, Carl H. Poppe, Carl M. Servin, Caba Calic
  • Patent number: 8430949
    Abstract: A liquid degassing apparatus is arranged to limit pervaporation through a membrane by establishing a pervaporation control space at a permeate side of the membrane. The pervaporation control space is defined in a vacuum chamber between the membrane and a shield member. The shield member may be substantially gas and liquid impermeable to maintain an environment in contact with the permeate side of the membrane that is relatively rich in solvent vapor concentration, thereby limiting further liquid pervaporation across the membrane.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: April 30, 2013
    Assignee: IDEX Health & Science LLC
    Inventors: Yuri Gerner, Quan Liu, Carl W. Sims
  • Patent number: 8415123
    Abstract: An apparatus and method for electromagnetic treatment of living tissues and cells comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a angiogenesis and neovascularization target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: April 9, 2013
    Assignee: Ivivi Health Sciences, LLC
    Inventors: Arthur A. Pilla, Andre′ A. DiMino
  • Patent number: 8343027
    Abstract: Methods and devices for providing electromagnetic field treatment to a subject having a metal-containing implant or prosthesis at or near the treatment site. These treatment methods can include calibrating the treatment devices such that the treatment field provided is not distorted or affected by the presence of metal in the target location. Additionally, embodiments of the invention provide for wearable and adjustable electromagnetic treatment devices with reinforcing support members to maintain the structure of flexible metal applicators, which generate the therapeutic electromagnetic field.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: January 1, 2013
    Assignee: Ivivi Health Sciences, LLC
    Inventors: Andre' A. DiMino, Matthew E. Drummer, Arthur A. Pilla
  • Publication number: 20120316130
    Abstract: A pharmaceutical composition for the treatment of an estrogen-dependent disease or condition comprises: (1) at least one polysaccharide selected from the group consisting of an alginate and a fucoidan in a quantity effective to treat an estrogen-dependent disease or condition; and (2) a pharmaceutically acceptable carrier. The composition can include both an alginate and a fucoidan. The composition can include other ingredients such as at least one compound selected from the group consisting of diindolylmethane and indole-3-carbinol in a quantity sufficient to inhibit the activity of estrogen. Methods for use of the composition for the treatment of an estrogen-dependent disease or condition, especially endometriosis, are described.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: Concourse Health Sciences LLC
    Inventor: Curt HENDRIX
  • Publication number: 20120288485
    Abstract: A formulation, composition or combination of substances comprising jasmonate for modulating melatonin production and/or calcification of a pineal gland and/or modulation and/or treatment of age-related neurodegeneration in a subject, particularly in a mammalian subject and more particularly in a human subject and use of jasmonate for modulating melatonin production and/or calcification of a pineal gland and/or modulation and/or treatment of age-related neurodegeneration is provided.
    Type: Application
    Filed: May 9, 2012
    Publication date: November 15, 2012
    Applicant: Broady Health Sciences, LLC.
    Inventor: Brunde Broady