Patents Assigned to Health & Science, LLC
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Patent number: 8696038Abstract: A fitting assembly is provided having a nut and a ferrule, which in certain embodiments may be assembled by an operator. The nut and ferrule of the fitting assembly have passageways therethrough for receiving and removably holding tubing. The nut and ferrule fitting assembly may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.Type: GrantFiled: March 2, 2012Date of Patent: April 15, 2014Assignee: IDEX Health & Science LLCInventor: Nathaniel Nienhuis
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Patent number: 8689824Abstract: A check valve construction is provided having: a movable disc with a flat surface on a first side and a convex shaped surface on the opposing side, a first seat on for the flat surface and a second seat for the convex surface, where the narrowest portion of the fluid path is defined by the equation: G 3 = 12 ? ? ? ? W ? ? Q ? ? ? D ? ? ? ? ? P Wherein G: the gap of most narrow passageway between the flat surface of the disc and disc seat; ?: dynamic viscosity of the fluid; D: mean diameter of the flat sealing surface of the disc; Q: desired fluid flow rate; W: breadth of the flat sealing surface of the disc; ?P: pressure differential across the gap (G).Type: GrantFiled: March 21, 2011Date of Patent: April 8, 2014Assignee: IDEX Health & Science, LLCInventor: Zhenxing Dong
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Publication number: 20140090250Abstract: A multi-position valve assembly including a valve housing, a stator element and a rotor element rotatably mounted about a rotational axis. The valve assembly further includes a pressure adjustment assembly movable between a release position and a stop position, hard stopped relative to the valve housing. The pressure adjustment assembly includes a pressure adjuster device configured to movably cooperate between the rotor element and the valve housing to adjustably generate an axial compression pressure at the rotor-stator interface at a calibrated operating pressure, PC. When the pressure adjustment assembly is oriented in the release position, the axial compression pressure is substantially removed from the rotor-stator interface. In contrast, when the pressure adjustment assembly is oriented in the stop position, the axial compression pressure is substantially reproduced at the calibrated operating pressure, PC.Type: ApplicationFiled: December 5, 2013Publication date: April 3, 2014Applicant: IDEX Health & Science LLCInventors: Christopher R. TOWER, Mark J. GREEN
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Patent number: 8668763Abstract: A liquid degassing apparatus is arranged to prevent pervaporated solvent cross-contamination by counteracting liquid vapor pervaporation flow. Liquid vapor pervaporation cross-contamination among a plurality of degassing modules is counteracted with specifically configured volumes and bleed inlet flow to conduits fluidly coupling permeate sides of said plurality of degassing chambers.Type: GrantFiled: January 24, 2012Date of Patent: March 11, 2014Assignee: IDEX Health & Science LLCInventor: Yuri Gerner
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Publication number: 20140026647Abstract: A fitting assembly having a nut, a ferrule, and a ferrule tip that may be assembled by an operator. The fitting assembly includes a nut with first and second ends, with the second end adapted to receive the first end of a ferrule, and a ferrule tip with a first end having an externally tapered portion adapted to abut the second end of the ferrule and a second end adapted to be received in a component or fitting of a liquid chromatography system. The nut, ferrule and ferrule tip of the fitting assembly have passageways therethrough for receiving and removably holding tubing.Type: ApplicationFiled: September 26, 2013Publication date: January 30, 2014Applicant: IDEX Health & Science LLCInventors: Scott J. Ellis, Eric Beemer, Nathaniel Nienhuis, Craig W. Graham, Troy N. Sanders
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Patent number: 8627851Abstract: A multi-position valve assembly including a valve housing, a stator element and a rotor element rotatably mounted about a rotational axis. The valve assembly further includes a pressure adjustment assembly movable between a release position and a stop position, hard stopped relative to the valve housing. The pressure adjustment assembly includes a pressure adjuster device configured to movably cooperate between the rotor element and the valve housing to adjustably generate an axial compression pressure at the rotor-stator interface at a calibrated operating pressure, PC. When the pressure adjustment assembly is oriented in the release position, the axial compression pressure is substantially removed from the rotor-stator interface. In contrast, when the pressure adjustment assembly is oriented in the stop position, the axial compression pressure is substantially reproduced at the calibrated operating pressure, PC.Type: GrantFiled: June 14, 2010Date of Patent: January 14, 2014Assignee: Idex Health & Science LLCInventors: Christopher R. Tower, Mark J. Green
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Patent number: 8622086Abstract: A micro-fluidic valve system is provided which includes a micro-fluidic valve actuator apparatus, a fluid distribution manifold and a micro-fluidic POD apparatus. The POD apparatus includes a POD housing that defines an interior central passage extending from a distal mounting end of the housing to a proximal portion thereof. The POD apparatus further includes a stator device disposed in the interior central passage, and includes a distal stator face that cooperates with an opening in the distal mounting end to define a gasket receptacle. A relatively thin, elastomeric gasket member is disposed in the gasket receptacle of the housing in abutting contact between the stator and a communication face of the manifold. A fluid-tight seal is then formed between each respective stator communication port of the stator device and a corresponding manifold communication port of the manifold.Type: GrantFiled: February 25, 2011Date of Patent: January 7, 2014Assignee: Idex Health & Science LLCInventor: Carl M. Servin
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Patent number: 8569070Abstract: A fitting assembly having a nut, a ferrule, and a ferrule tip that may be assembled by an operator. The fitting assembly includes a nut with first and second ends, with the second end adapted to receive the first end of a ferrule, and a ferrule tip with a first end having an externally tapered portion adapted to abut the second end of the ferrule and a second end adapted to be received in a component or fitting of a liquid chromatography system. The nut, ferrule and ferrule tip of the fitting assembly have passageways therethrough for receiving and removably holding tubing.Type: GrantFiled: July 16, 2010Date of Patent: October 29, 2013Assignee: IDEX Health & Science LLCInventors: Scott J. Ellis, Eric Beemer, Nathaniel Nienhuis, Craig W. Graham, Troy N. Sanders
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Publication number: 20130233053Abstract: A torque limited fitting is provided having a head and a body, which in certain embodiments may be assembled by an operator. The body of the torque limited fitting has a passageway therethrough for receiving and removably holding tubing. The torque limited fitting may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.Type: ApplicationFiled: November 2, 2012Publication date: September 12, 2013Applicant: IDEX Health & Science LLCInventors: Eric Beemer, Craig Graham, Mark Hahn
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Publication number: 20130234432Abstract: A microfluidic interconnect system and method for assembly thereof is described. The microfluidic interconnect has a port and a seal, with the port having a reverse taper. The port has a first port end, a second port end, and an inner port surface with a tapered portion. Each port end has an opening with a diameter, and in certain embodiments, the diameter of the first port end is smaller than the diameter of the second port end. The seal has a first end and a second end, and each seal end has a rim and an opening with an inner diameter and an outer diameter. The seal also has an inner surface and an outer surface, where in certain embodiments, each surface has a tapered portion.Type: ApplicationFiled: November 27, 2012Publication date: September 12, 2013Applicant: IDEX Health & Science LLCInventor: Craig Graham
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Patent number: 8528592Abstract: A check valve construction is provided in which a moveable a movable ball having a convex surface resides in a cage having a conical frustum chamber and a seat for the ball. A fluid path between the ball and the cage is defined by the equation: G = D ? ? cos ? ( b - a ) 2 ? ? cos ? ? b - d 2 wherein G is the gap of the narrowest passageway of the fluid path, D is the diameter of the small end of the conical frustum chamber of the cage, d is the diameter of the convex surface of the ball, a is the angle between a vertical diameter of the ball and the position of the narrowest gap on the convex surface of the ball, and, b is the angle between the vertical diameter of the movable element and the position of the small end of conical frustum chamber of the cage.Type: GrantFiled: February 28, 2011Date of Patent: September 10, 2013Assignee: Idex Health & Science, LLCInventor: Zhenxing Dong
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Publication number: 20130227831Abstract: A fitting assembly is provided having a nut and a ferrule, which in certain embodiments may be assembled by an operator. The nut and ferrule of the fitting assembly have passageways therethrough for receiving and removably holding tubing. The nut and ferrule fitting assembly may be adapted for use with a flat bottom port, such as in an analytical instrument, like liquid chromatography, gas chromatography, ion chromatography, or in in vitro diagnostic systems.Type: ApplicationFiled: March 2, 2012Publication date: September 5, 2013Applicant: IDEX Health & Science LLCInventor: Nathaniel Nienhuis
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Publication number: 20130196001Abstract: Presented are salt replacement compositions and methods which are useful for replacing dietary sodium and for preventing and treating diseases associated with sodium overconsumption, including diabetes-Type 2.Type: ApplicationFiled: January 23, 2013Publication date: August 1, 2013Applicant: Health & Science, LLCInventor: Health & Science, LLC
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Patent number: 8440003Abstract: A liquid degassing apparatus is arranged to limit pervaporation through a membrane by attenuating pressure oscillations developed by a vacuum pump. The attenuation is obtained through a combination of one or more flow restrictors and added volume chambers fluidly interposed between the degassing chamber and the vacuum pump. The pressure oscillation attenuation may further inhibit cross-contamination of pervaporated solvents among a plurality of distinct degassing chambers.Type: GrantFiled: June 29, 2011Date of Patent: May 14, 2013Assignee: IDEX Health & Science, LLCInventors: Yuri Gerner, Quan Liu, Carl W. Sims
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Patent number: 8431020Abstract: A liquid dispensing system is provided for automated dispensing of a plurality of liquid reagents into a recreational body of water. The liquid dispensing system includes a cartridge apparatus housing a plurality of liquid reagent containers, each containing a respective liquid reagent. A docking assembly is provided having a dock manifold device, and is releasably coupled to the cartridge apparatus between a first condition and a second condition. In a first condition, the cartridge apparatus can be removably coupled to the docking assembly, while in the second condition, the cartridge apparatus is lockably mounted to the docking assembly in a manner permitting fluid communication from the respective reagent container to respective fluid passages of the manifold device. The dispensing system further includes a dosing engine having a valve manifold device to selectively dispense the liquid reagents into the recreational body of water through a dispensing port.Type: GrantFiled: May 11, 2009Date of Patent: April 30, 2013Assignee: Idex Health & Science LLCInventors: Michael R. Straka, Carl H. Poppe, Carl M. Servin, Caba Calic
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Patent number: 8430949Abstract: A liquid degassing apparatus is arranged to limit pervaporation through a membrane by establishing a pervaporation control space at a permeate side of the membrane. The pervaporation control space is defined in a vacuum chamber between the membrane and a shield member. The shield member may be substantially gas and liquid impermeable to maintain an environment in contact with the permeate side of the membrane that is relatively rich in solvent vapor concentration, thereby limiting further liquid pervaporation across the membrane.Type: GrantFiled: March 25, 2011Date of Patent: April 30, 2013Assignee: IDEX Health & Science LLCInventors: Yuri Gerner, Quan Liu, Carl W. Sims
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Patent number: 8415123Abstract: An apparatus and method for electromagnetic treatment of living tissues and cells comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a angiogenesis and neovascularization target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said angiogenesis and neovascularization target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said angiogenesis and neovascularization target pathway structure using a coupling device.Type: GrantFiled: March 15, 2010Date of Patent: April 9, 2013Assignee: Ivivi Health Sciences, LLCInventors: Arthur A. Pilla, Andreā² A. DiMino
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Patent number: 8343027Abstract: Methods and devices for providing electromagnetic field treatment to a subject having a metal-containing implant or prosthesis at or near the treatment site. These treatment methods can include calibrating the treatment devices such that the treatment field provided is not distorted or affected by the presence of metal in the target location. Additionally, embodiments of the invention provide for wearable and adjustable electromagnetic treatment devices with reinforcing support members to maintain the structure of flexible metal applicators, which generate the therapeutic electromagnetic field.Type: GrantFiled: January 30, 2012Date of Patent: January 1, 2013Assignee: Ivivi Health Sciences, LLCInventors: Andre' A. DiMino, Matthew E. Drummer, Arthur A. Pilla
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Publication number: 20120316130Abstract: A pharmaceutical composition for the treatment of an estrogen-dependent disease or condition comprises: (1) at least one polysaccharide selected from the group consisting of an alginate and a fucoidan in a quantity effective to treat an estrogen-dependent disease or condition; and (2) a pharmaceutically acceptable carrier. The composition can include both an alginate and a fucoidan. The composition can include other ingredients such as at least one compound selected from the group consisting of diindolylmethane and indole-3-carbinol in a quantity sufficient to inhibit the activity of estrogen. Methods for use of the composition for the treatment of an estrogen-dependent disease or condition, especially endometriosis, are described.Type: ApplicationFiled: August 22, 2012Publication date: December 13, 2012Applicant: Concourse Health Sciences LLCInventor: Curt HENDRIX
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Publication number: 20120288485Abstract: A formulation, composition or combination of substances comprising jasmonate for modulating melatonin production and/or calcification of a pineal gland and/or modulation and/or treatment of age-related neurodegeneration in a subject, particularly in a mammalian subject and more particularly in a human subject and use of jasmonate for modulating melatonin production and/or calcification of a pineal gland and/or modulation and/or treatment of age-related neurodegeneration is provided.Type: ApplicationFiled: May 9, 2012Publication date: November 15, 2012Applicant: Broady Health Sciences, LLC.Inventor: Brunde Broady