Abstract: A kit for producing bone cement includes at least one paste A and one paste B. Paste A contains at least one monomer (a1) for radical polymerization; at least one polymer (a2) insoluble in monomer (a1); at least one polymer (a3) soluble in monomer (a1); and at least one radical polymerization initiator (a4). The weight ratio of the at least one polymer (a2) to the at least one polymer (a3) is at least 2 to 1. Paste B contains at least one monomer (b1) for radical polymerization; at least one polymer (b2) and at least one accelerator (b3) soluble in monomer (b1); and optionally a polymer (b4) insoluble in monomer (b1). The maximum quantity of polymer (b4) is 5% by weight, relative to the total weight of paste B. The weight ratio of polymer (b4) to the at least one polymer (b2) is no more than 0.2.

Abstract: Methods and devices coat, at least regions of, a medical implant, preferably of an artificial joint or a fixation for a joint. The method provides a medical implant, fills a device with a liquid having at least one pharmaceutically active substance, wherein the device has a compressed, at least over regions thereof, elastic, porous transfer means increases a volume of the transfer means, whereby the liquid is taken up at least partly into the pores of the transfer means, and transfers the liquid from the transfer means to a medical implant surface to be coated. The device coats, at least regions of, a medical implant, by means of the method, whereby the device has a compressed, at least over regions thereof, elastic, porous transfer means.

Abstract: The invention relates to a knee spacer for temporary replacement of an artificial knee joint, whereby the knee spacer comprises a tibial component and a femoral component as separate components, which can be moved with respect to each other when inserted in a patient, and whereby the tibial component and the femoral component each comprise at least one running surface by means of which the tibial component and the femoral component can be placed against each other such as to be mobile in their patient-inserted state, and the tibial component comprises an anchoring surface that is arranged opposite to the running surface side and is provided for connecting the tibial component to the tibia by means of a bone cement, and the femoral component to comprise an anchoring surface that is arranged opposite to the running surface side and is provided for connecting the femoral component to the femur, whereby the tibial component and the femoral component each comprise at least two recesses that extend from the anchori

Abstract: A paste is provided from which bone cement can be formed, which is to the largest extent possible bubble-free and has a high impact strength. The paste includes (i) 15-50 weight percent of at least one mono-functional, hydrophobic methacrylic acid ester, (ii) 40-85 weight percent of at least one filler, (iii) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having at least one peroxide group, (iv) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having no peroxide groups, (v) 0.000001-3 weight percent of at least one accelerator soluble in the methacrylic acid ester (i) and capable of forming radicals from the radical initiators according to (iii) and (iv), (vi) 0.001-5 weight percent of at least one halide salt, and (vii) 0.2-3 weight percent of at least one cross-linking agent.

Abstract: A cartridge system has two cartridges and a discharge opening, wherein the cartridges are delimited by cartridge walls and by a cartridge head, wherein at least one cartridge opening for expelling the cartridge contents from both cartridges is provided in each case in the cartridge head. A device regulates streams of fluid from the cartridges and is arranged rotatably or slideably on the cartridge head, wherein on at least two openings at least one wing is in each case arranged which at least in some areas protrudes past the opening, such that a flow through the openings applies to the device a force which force leads to a sliding or turning of the device against the cartridge head, such that a housing having a discharge opening is arranged on the cartridge head, in which the housing is arranged so as to rotate or slide.

Abstract: A device (10) for mixing and dispensing bone cement includes a mixing cylinder (20), in which a mixing plunger (21) is arranged, the mixing plunger (21) being axially movable by an actuation rod (50) guided out in a sealed manner at a first cylinder end (30). A sealing plunger (42) is arranged in a region of the first cylinder end (30), is axially movable on the actuation rod (50) and seals the mixing cylinder (20) in a gas-tight manner. A sterilization plunger (41) is arranged in the region of the first cylinder end (30) between the mixing plunger (21) and the sealing plunger (42), is axially movable on the actuation rod (50) separately from the sealing plunger (42), and seals the mixing cylinder (20) in a gas-permeable manner. The sterilization plunger (41) and the sealing plunger (42) form a two-part plunger system (40).

Abstract: A local system for the release of active principle is described which consists of approximately spherical or rotation symmetrical bodies which are composed essentially of polymethyl methacrylate or polymethyl methacrylate co-methyl acrylate, zirconium dioxide or barium sulphate and one or more pharmaceutical active principles, in particular antibiotics, and which are produced by radical polymerization, radical polymerization activators effective in the temperature range of 10-80° C. or residues of these polymerization activators from the groups of aromatic amines, heavy metal salts and barbiturates not being contained therein.

Abstract: The invention proposes an antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement, that can be cured and comprises a content of at least one component that is a compound with an oxidising effect or from which a compound with an oxidising effect can be released. Preferably, hydrogen peroxide is or can be released. In this context, it is particularly preferred to use an adduct or a salt of hydrogen peroxide that releases hydrogen peroxide in the presence of water or aqueous conditions. The antiseptic polymethylmethacrylate bone cement can be used for mechanical fixation of primary total articular endoprostheses, for mechanical fixation of revision total articular endoprostheses, and for producing spacers.

Abstract: A device, for mixing and dispensing a pasty mass, comprising a cartridge that is open or can be opened on two ends and has a mixing element and a feed plunger arranged in it, whereby the feed plunger, in a starting position, is arranged in the region of a first cartridge end, the mixing element is arranged on a mixing rod, the mixing rod extends through the feed plunger into the inside of the cartridge, the mixing rod and the feed plunger and the cartridge together form a tight connection that seals the cartridge inside of the device with respect to the exterior, whereby the feed plunger is arranged on the mixing rod and such that it can move in the cartridge in axial direction and whereby at least one clamping jaw is arranged on the feed plunger in appropriate manner such that the clamping jaw can be pressed onto the mixing rod by means of a locking element such that the mixing rod can no longer be shifted with respect to the feed plunger.

Abstract: A device releases a fluid active substance, the device has at least one hollow space containing the fluid active substance, whereby the device contains water and a reducing agent, which are or can be made to be in communication such that a chemical reaction of the water and the reducing agent produces a gas and the gas effectively communicates with the fluid active substance such that the gas pressure thus generated presses the fluid active substance out of at least one opening of the hollow space out of the device. A medical implant incorporates the device, and a method releases a fluid active substance from a hollow space of the medical implant, in which a gas is produced through a chemical reaction of liquid water and a reducing agent, and the resulting gas pressure is used to expel the fluid active substance out of at least one opening of the hollow space.

Abstract: A dispensing device dispenses flowable materials from cartridges, whereby the dispensing device comprises a base body, a connecting element for a gas cartridge on the base body, a valve element for controlling a gas flow from the gas cartridge, and a gas-permeable channel connecting the connecting element to the valve element. At least one evaporation container is arranged in the gas-permeable channel such that the gas flow from the gas cartridge is guided through the evaporation container, at least over regions thereof.

Abstract: A rotary valve body for a bone cement dispensing device is arrangeable in rotatable manner in a matching valve seat in the dispensing device, whereby the rotary valve body is rotationally symmetrical about the rotation axis of the rotary valve body at least within a region intended for the valve seat. At least one sealing cam made of an elastic plastic material is arranged on the rotationally symmetrical jacket surface of said region and is raised above the radius of the rotationally symmetrical jacket surface such that the sealing cam renders the circumference of the rotary valve body larger than the internal diameter of the valve seat. At least one feed-through is arranged in the rotary valve body and extends from a first opening in the rotationally symmetrical jacket surface of the rotary valve body in the region of the sealing cam into a second opening in the rotationally symmetrical jacket surface of the rotary valve body.

Abstract: A bone cement system (100) is provided having a mixing facility (10) for mixing and dispensing of bone cement, a reservoir container (112) for a monomer, and a conveyor (122). The mixing facility (10) has a mixing cylinder (20), which stores a bone cement powder. The monomer can be conveyed from the reservoir container (112) into the mixing cylinder (20) by the conveyor (122). A sieve element is (4) is arranged between the reservoir container (112) and the mixing facility (10), in order to prevent ingress of the bone cement powder from the mixing cylinder (20) into the conveyor (122). The mixing device (10) included a dispensing opening (23) for dispensing a bone cement mixed from the bone cement powder and the monomer. The dispensing opening (23) includes a shield (1) having at least one through-opening (2). The ratio of the area of the through-opening (2) to the area of the sieve element (4) is at least 1 to 3, and the distance between the shield (1) and the sieve element (4) is at least 1 mm.

Abstract: The invention relates to a method for coating of a medical implant that can be used to apply a calcium salt to the surface of a medical implant easily and without expensive coating equipment and little expenditure of time. Accordingly, a method is provided that includes (I) providing a medical implant that includes at least one surface to be coated; (ii) providing a body that includes at least one calcium salt with a Mohs hardness of no more than 5.5 on at least one of its surfaces; and (iii) rubbing said body having the calcium salt-containing surface onto the at least one medical implant surface to be coated in order to coat said surface of the medical implant with the at least one calcium salt.

Abstract: A paste contains at least one monomer for radical polymerisation, at least one polymer that is soluble in said at least one monomer for radical polymerisation, and at least one filling agent that is poorly soluble or insoluble in said at least one monomer for radical polymerisation. The filling agent is a particulate inorganic calcium salt comprising the following properties: at least 90% by weight of the particulate inorganic calcium salt have a particle size of less than 63 ?m, as determined by means of sieve analysis; and the solubility in water of the particulate inorganic calcium salt at 20° C. is less than 8.5 g per litre. A kit and the paste is usable for mechanical fixation of articular endoprostheses, for covering skull defects, for filling bone cavities, for femuroplasty, for vertebroplasty, for kyphoplasty, for the manufacture of spacers or for the production of carrier materials for local antibiotics therapy, as well as a form body.

Abstract: A medical system (10) is provided having a pulling device (20) and an active substance chain (50). The active substance chain (50) has at least two storage units (51) arranged like a chain, and at least one of the storage units (51) is loaded with a medicinal active substance. The pulling device (20) has a grip element (30) and a coupling element (40), and the coupling element (40) has at least one recess (41, 41?). In a free position (100) the active substance chain (50) is arranged separated from the pulling device (20), while in an inserted position (110) at least one of the storage units (51) is arranged form-fitting in a recess (41, 41?). The active substance chain (50) can be moved reversibly from the free position (100) into the inserted position (110).

Abstract: Cartridge systems for application of a material have at least one cartridge having cartridge walls, a cartridge head having at least one opening in the cartridge head, and a bracket arranged on the cartridge head. A valve is mounted in rotatable manner in the bracket and has at least one passage through the valve that is connected to an outlet opening of the valve. In a closed position, the valve closes the at least one opening of at least one cartridge in a sealed manner. The at least one passage of the valve is connected to the at least one opening when the valve is located in an open position such that the cartridge content is squeezable out of the at least one cartridge through the outlet opening, and further wherein the valve is configured to be transitioned from a closed position to an open position through a rotation of the valve about an axis of symmetry of the valve.

Abstract: A kit is provided based on two pastes designed to produce bone cement with high initial stability and therefore low post-cure. The kit includes a paste A and a paste B, wherein paste A contains (a1) a polymerizable monomer having a pH in water in the range of 5-9, (a2) a filling agent insoluble in (a1), and (a3) a barbituric acid derivative selected from the group consisting of 1,5-disubstituted barbiturates, 1,3,5-trisubstituted barbiturates, and 1,3,5-tetrasubstituted barbiturates, and paste B contains (b1) a polymerizable monomer having a pH in water in the range of 5-9, (b2) a filling agent insoluble in (b1), (b3) a peroxide soluble in (b1), (b4) a heavy metal compound insoluble in (b1) and selected from the group consisting of heavy metal salts and heavy metal complexes, and wherein at least one of the pastes A and B contains a halide salt.

Abstract: Cartridge systems for application of a material have at least one cartridge having cartridge walls, a cartridge head having at least one opening in the cartridge head, and a bracket arranged on the cartridge head. A valve is mounted in rotatable manner in the bracket and has at least one passage through the valve that is connected to an outlet opening of the valve. In a closed position, the valve closes the at least one opening of at least one cartridge in a sealed manner. The at least one passage of the valve is connected to the at least one opening when the valve is located in an open position such that the cartridge content is squeezable out of the at least one cartridge through the outlet opening, and further wherein the valve is configured to be transitioned from a closed position to an open position through a rotation of the valve about an axis of symmetry of the valve.

Abstract: A mixing device produces a multi-component mixture, in particular for medical applications, and has at least one first component and one second component, whereby the first component is a pasty fluid mass, whereby the mixing device has a housing having at least one first opening and a hollow body, whereby the hollow body has an internal space that contains the second component, and the mixing device has a feed plunger for expelling the second component from the internal space of the hollow body, whereby the hollow body has a thread and the feed plunger has a counter-thread that engages the thread of the hollow body, and the mixing device has a propulsion element that is arranged inside the housing, whereby the propulsion element converts a flow of the first component through the housing into a rotary motion, whereby the rotary motion of the propulsion element screws the feed plunger into the internal space of the hollow body, and whereby the second component can thus be extruded from the hollow space into the