Abstract: Dispensing device for polymethylmethacrylate bone cements comprising a manually actuatable rocker lever, an adapter for a cement cartridge, a movable clamping rod, a propulsion body shiftable in axial direction of the clamping rod, at least one sphere-shaped or roller-shaped clamping body arranged in a cavity of the propulsion body, an elastic element pushing the clamping body onto an inclined surface or edge of the cavity of the propulsion body, a spring element which pushes on the at least one propulsion body opposite to the propulsion direction of the clamping rod, at least one securing element touching against the clamping rod, at least one sphere-shaped or roller-shaped clamping body arranged in a cavity of the securing element, an elastic element pushing the at least one clamping body of the securing element onto an inclined surface or edge of the cavity of the at least one securing element.

Abstract: A mixing device, for a mixable material, has at least one cartridge and a closure piece. The cartridge contains a first component of the mixable material and has a cartridge head in which at least one air opening is arranged, and the closure piece is arranged on the cartridge head in such a way that the at least one air opening in the cartridge head can be closed and opened by the closure piece. The closure piece is mounted so as to be rotatable or slideable relative to the cartridge head, and a connection extends through the cartridge head or a cartridge wall into the interior of the cartridge and connects the interior of the cartridge to a container for a second component of the mixable material.

Abstract: A device automatically mixes bone cement and has two separate plunger space sections with a gas feed and a gas outlet, which are separated from each other through a plunger. A blocking organ is provided in the plunger and can be switched at the turnaround points of the plunger path. Suitable connecting facilities connect the plunger to a mixing facility that is arranged in a mixing vessel. Alternating build-up of a pressure difference and pressure equalization in both plunger space sections causes the plunger to move up and down. The plunger motion effects a simultaneous up-and-down motion and rotation of the mixing facility.

Abstract: The invention relates to a device for vial opening comprising an external container, in which a closed vial having a vial body and a vial head is arranged, and comprising a hollow space in the region of the vial head, whereby the hollow space comprises at least one opening and a connection to the vial, whereby the vial head, at least regions thereof, is arranged in the connection of the hollow space to the vial, and the walls of the external container comprise at least one deformable region or are altogether made of a deformable material, whereby tilting of the vial with respect to the connection is made feasible, and the diameter of the connection is adapted to the dimensions of the vial head in such a manner that the vial head can be fractured or broken off the vial body when the vial is being tilted with respect to the connection.

Abstract: A discharge device discharges the content of a container by applying a compressed gas. The device has a housing, at least one compressed gas container, an operating device for setting a gas flow from the compressed gas container and an opening means for opening the compressed gas container. The opening means is movable in relation to the compressed gas container, and the device has a holder for securing the container on the device. The holder is in operative connection with the opening means in such a way that securing the container on the holder brings about a movement of the opening means in relation to the compressed gas container that opens the compressed gas container.

Abstract: Paste application system having a two-component cartridge with two axially shiftable feed plungers; one hollow cylinder with an open front face and an at least partially closed front face, an axially mobile first plunger situated therein with two pestles attached to it; another hollow cylinder that contains a manually shiftable second plunger; and a liquid container, whereby the second hollow cylinder is connected or connectable to the liquid container in liquid-permeable manner by a first conduit means and a first non-return valve, and the first hollow cylinder is connected or connectable to the second hollow cylinder in liquid-permeable manner by a second conduit means and a second non-return valve; whereby the two-component cartridge and the first hollow cylinder, arranged axially adjacent, with the axially mobile pestles are arranged in a pressure container; and the paste application system contains a hollow space and liquid is present in said space.

Abstract: A vacuum cementing system has at least one cement powder cartridge and a container-opening system. The container-opening system has at least one container for at least one liquid and/or at least one powder, an opening device, and an outlet opening for applying a negative pressure. When a negative pressure is being applied, the opening device is mobile relative to at least a part of the at least one container. The vacuum cementing system has a means for connecting the cement powder cartridge to the at least one container and utilizes necessary vacuum for automatically opening the at least one container.

Abstract: Opening device for the opening of a monomer liquid container (1) comprising a positioning aid (6) for positioning of the monomer liquid container (1), an opening facility (8) for the opening of the monomer liquid container (1), the opening facility (8) being mobile with respect to the positioning aid (6) and/or the positioning aid (6) being mobile with respect to the opening facility (8), at least one elastically deformable energy-storing element (9) for storage of elastic energy, whereby a motion of the opening facility (8) and/or a motion of the positioning aid (6) can be driven by the elastic energy of the at least one elastically deformable energy-storing element (9).

Abstract: A vacuum cementing system has at least one cement powder cartridge and a container-opening system. The container-opening system has at least one container for at least one liquid and/or at least one powder, an opening device, and an outlet opening for applying a negative pressure. When a negative pressure is being applied, the opening device is mobile relative to at least a part of the at least one container. The vacuum cementing system has a means for connecting the cement powder cartridge to the at least one container and utilizes necessary vacuum for automatically opening the at least one container.

Abstract: The invention relates to an anti-infective spacer for osteosynthesis plates comprising a plate having at least one opening for accommodating a screw, whereby the plate is made up of at least one biocompatible material, in which at least one antimicrobial substance is distributed, dispersed or dissolved. The invention also relates to a set comprising at least one osteosynthesis plate and at least one said spacer, preferably comprising at least one screw for each recess of each spacer.

Abstract: A vacuum mixing system for the mixing of polymethylmethacrylate bone cement comprising at least one cartridge (4) having an evacuatable internal space (5) for the mixing of the bone cement, the internal space (5) of which comprises a cylindrical swept volume, a mixing element (12) that is arranged in the internal space (5) of the cartridge (4) such as to be mobile and can be operated from outside the vacuum mixing system in order to mix the content in the internal space (5) of the cartridge (4), and a dispensing plunger (2) having a cylindrical external circumference whose first base surface borders a base surface of the internal space (5) of the cartridge (4) and which can be or is locked to the cartridge (4) in detachable manner and which, in the detached state, is mobile in the cylindrical region of the internal space (5) of the cartridge (4).

Abstract: The subject matter of the invention is a curable composition for use as bone cement, in particular for augmentation of osteoporotic bone tissue, comprising at least one organic polymer and at least one monomer for radical polymerization, at least one particulate inorganic additive having a BET surface of at least 40 m2/g, whereby the additive comprises covalently bound hydroxyl groups, whereby the composition further comprises at least one fatty acid ester or a mixture of fatty acid esters. Another subject matter of the invention is the use of said composition for augmentation of osteoporotic bone tissue and particularly preferably for vertebroplasty, kyphoplasty, and augmentation of drill holes in osteoporotic bone tissue, as well as a kit for producing said composition.

Abstract: A medical spray device has a compressed gas supply conduit for guiding a gas flow, a liquid supply conduit for supplying a liquid, a dispensing tube having an open tube end for spraying fine droplets or a spray mist of a liquid-gas mixture, and an operable valve element that is arranged in the compressed gas supply conduit. A constriction of the cross-sectional area is provided in the dispensing tube and a merging site is arranged in the region of the constriction through which the liquid merges into the gas flow from the compressed gas supply conduit, whereby the constriction forms a nozzle in the dispensing tube. A spray device kit provides a medical spray device, a gas supply conduit, a pressure regulator, and a compressed gas container.

Abstract: A vacuum mixing system for the mixing of polymethylmethacrylate bone cement, comprising at least one cartridge (4) having an evacuable internal space for mixing of the bone cement, a pump (18) for generating a negative pressure, and a connecting conduit (12) connecting the internal space of the at least one cartridge (4) to the pump (18) for generating a negative pressure, an integrated energy reservoir (28) for driving the pump (18) that is or can be connected to the pump (18) and has energy for at least one pumping process of the pump (18) stored in it, whereby a negative pressure can be generated by means of the pump (18) during the pumping process, which negative pressure can be used to evacuate gas from the internal space of the at least one cartridge (4) through the connecting conduit (12).

Abstract: A manually drivable device for the mixing of a pasty mixing ware from at least two fluid starting components comprising at least two cartridges having feed plungers; a mixing space to mix the starting components, mixing vanes being provided in the mixing space and mounted such that they can rotate; a lever rotatable about a pivot point operatable manually or a pin that can be shifted in longitudinal direction and operatable manually in order to operate the device; a gear connected to the lever or pin, and connected to the rotatable mixing vanes in the mixing space; and a facility for propelling the feed plungers such that the motion of the lever or pin drives the rotation of the mixing vanes in the mixing space and motion of the feed plungers into the cartridges. The invention also relates to a method for mixing fluid starting components using the device.

Abstract: The present invention relates to a pasty composition, at least containing particles of at least one calcium salt, whereby the particles of the at least one calcium salt are at least partly coated with at least one saturated fatty acid ester (a) that has a melting temperature of at least 45° C., and said particles that are at least partly coated with the saturated fatty acid ester (a) are mixed with at least one saturated fatty acid ester (b) that has a melting temperature below 25° C. to form a pasty composition. The invention also relates to a method for producing a pasty composition, the pasty composition obtainable through said method, and the use of a pasty composition as bone replacement material.

Abstract: The invention relates to a fosfomycin preparation that comprises a) a calcium salt of fosfomycin and b) at least one sugar alcohol having a melting point above 70° C., whereby the weight ratio of sugar alcohol to calcium salt of fosfomycin is at least 0.8. Moreover, the invention proposes a method for producing the fosfomycin preparation and a polymethylmethacrylate bone cement powder that contains the fosfomycin preparation.

Abstract: Device and method for degassing and dispensing bone cement that can be used to produce a bone cement that is largely free of air inclusions. The device contains a dispensing tube (1) that comprises at least one section (2,3) that is permeable to gas, but impermeable to bone cement. The bone cement is being moved along the gas-permeable section which causes the gas present in the bone cement to flow through the gas-permeable material.

Abstract: A paste is provided from which bone cement can be formed, which is to the largest extent possible bubble-free and has a high impact strength. The paste includes (i) 15-50 weight percent of at least one mono-functional, hydrophobic methacrylic acid ester, (ii) 40-85 weight percent of at least one filler, (iii) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having at least one peroxide group, (iv) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having no peroxide groups, (v) 0.000001-3 weight percent of at least one accelerator soluble in the methacrylic acid ester (i) and capable of forming radicals from the radical initiators according to (iii) and (iv), (vi) 0.001-5 weight percent of at least one halide salt, and (vii) 0.2-3 weight percent of at least one cross-linking agent.

Abstract: A device stores and mixes a liquid and a solid component, in particular, the device mixes and stores a monomer liquid and a powder for producing bone cement. The device contains two chambers of which the first chamber contains the solid component and is separated from a second chamber that contains the liquid component by means of a separation that can be opened. A mixing facility that can be driven by means of a pressure difference is arranged in the first chamber. In the present storage and mixing system, a vacuum that is available in the operating theatre is used to mix a monomer liquid and a bone cement powder in a vacuum and to operate a mixing facility simultaneously. Moreover, the vacuum can also be used to open a separation between monomer liquid and mixing space and to transfer the monomer liquid into the mixing space.