Abstract: The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alklyene glycol-graft-lactate) that is crosslinked by at least one hydrolysable monmer. Another embodiment of the present invention is a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent. Another embodiment of the present invention is a polymer particle comprising, a crosslinked copolymer comprises structures represented by Formulas (I), (II), and (III), where Formulas (I), (II) and (III) are defined in the specification. Yet other embodiments of the present invention include a method of preparing a methacrylate terminated macromonomer, a method of preparing a crosslinking agent, and a method of preparing a therapeutic agent loaded nanosphere by dispersion polymerization.

Abstract: A nanolubricant composition is described where the lubricant composition includes a flowable oil or grease with a multi-component nanoparticle dispersed in the flowable oil or grease. The multi-component nanoparticle includes a first nanoparticle component which effects thermal conductivity at a part interface and a second nanoparticle component which effects shearing at a part interface.

Abstract: A nanolubricant composition is described where the lubricant composition includes a flowable oil or grease with nanoparticles dispersed in the flowable oil or grease. The nanoparticles are configured to polish a surface of a structure slowly over a period of time. The nanoparticles a hardness of at least about 7 Mohs and a diameter that is less than one half the arithmetic average roughness of the surface or a length that is less than one half of the arithmetic average roughness of the surface.

Abstract: A signal is conducted from a controller module onto a network via a first coupling. The signal is transmitted across the network and received at one or more receiver modules via one or more second couplings. At the one or more receiver modules, the received signal is analyzed and based upon the analysis, a determination is made as to whether a fault has occurred in the network and/or where the occurrence occurred.

Abstract: A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like.

Abstract: A context of a mobile device is determined. A context preference of a user associated with the mobile device is determined. The context of the mobile device and the user context preference is transmitted to another node and responsively returned data is received. Available free space in the mobile device is determined. All data whose timestamp is within a predetermined threshold is cached. The data is cached in at least a portion of the free space.

Abstract: The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alkylene glycol-graft-acrylate) that is crosslinked by at least one hydrolysable monomer or crosslinking agent. The present invention is also directed to a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent (the crosslinking agent may be absent in the case of non-crosslinked particles). The present invention is still further directed to a polymer particle comprising a crosslinked copolymer, where the crosslinked copolymer includes structures represented by Formulas (I), (II), and (III), as defined in the specification. Other embodiments of the present invention also include methods of manufacturing polymer particles.

Abstract: The present invention is directed to a crosslinked or non-crosslinked polymer particle, wherein the crosslinked polymer particle comprises a copolymer of poly(alklyene glycol-graft-acrylate) that is crosslinked by at least one hydrolysable monomer or crosslinking agent. The present invention is also directed to a polymer particle comprising a crosslinked polymer particle that is a product of starting materials comprising (a) a hydrophilic monomer, (b) a hydrophobic monomer, and (c) a hydrolysable crosslinking agent (the crosslinking agent may be absent in the case of non-crosslinked particles). The present invention is still further directed to a polymer particle comprising a crosslinked copolymer, where the crosslinked copolymer includes structures represented by Formulas (I), (II), and (III), as defined in the specification. Other embodiments of the present invention also include methods of manufacturing polymer particles.

Abstract: A context of a mobile device is determined. A context preference of a user associated with the mobile device is determined. The context of the mobile device and the user context preference is transmitted to another node and responsively returned data is received. Available free space in the mobile device is determined. All data whose timestamp is within a predetermined threshold is cached. The data is cached in at least a portion of the free space.

Abstract: Data associated with at least one building condition or status is sensed by one or more sensors. The data from these sensors may be sent over a data bus and received by the central computer. In addition, a modulated signal may be transmitted by one or both of the transmitters across the data bus. The modulated signal is received at the receiver, which analyzes the received modulated signal, and determines whether an intermittent fault has occurred on the data bus based upon the analyzing. For example, the receiver may compare the received signal to an expected pattern and when a discrepancy exists, an intermittent fault is determined to exist. The receiver may also determine the location of the fault based upon the analysis.

Abstract: Methods and compositions are provided for treating an ocular disease in a subject in need thereof by increasing the bioavailability of a drug in the subject's eye. In one aspect, the ocular disease is at least one of diabetic retinopathy, macular degeneration, endopthalmitis, glaucoma, cataracts, ocular herpes. The methods and compositions provided herein include an efflux transporter inhibitor and a drug effective for treating the ocular disease. The efflux transporter inhibitor is effective to reduce the efflux of the drug through at least one of P-glycoprotein (Pgp), breast cancer resistant protein (BCRP), and multidrug resistant associated protein 1-9 (MRP1-9).

Abstract: A distance from a measurement point to a fault in a three-phase circuit is determined. The measurement point is located at an output of a power sub-station and the three phase circuit has a loop circuit having an associated net fault line current and a ground current. A derivative of the net fault line current of the loop circuit as measured from the measurement point is calculated. An uncompensated distance to the sub-cycle fault using at least the derivative of the net fault current is determined, and configured, to compensate for the ground current of the loop circuit. The compensation is applied to the uncompensated distance to produce a compensated distance to the sub-cycle fault.

Abstract: A nanothermocouple detector includes a nanowire coupled across two electrodes. The two electrodes are electrically connected to an amplifier. The two electrodes generally have a separation of about five micrometers to about thirty micrometers across which the nanowire is coupled. A focusing element is disposed to admit photons that fall on the focusing element onto the nanowire to heat it. A voltage change across the nanowire caused by the heating of the nanowire by the light is detected by the amplifier. The voltage change corresponds to the energy absorbed from the light by the nanowire. The color of a single photon can be detected using such device. An array of such devices can be used for sensing light on a two-dimensional scale, thereby providing an image showing small variances in the energies of the light impinging upon the detector array.

Abstract: A lighting element is disposed in an array of lighting elements. At the lighting element, a lighting status of at least one neighboring lighting element is sensed. Independent of any other lighting element, a lighting adjustment for the lighting element by applying the sensed lighting status to a predetermined rule is determined. The lighting adjustment is applied to the lighting element to adjust an illumination of the lighting element.

Abstract: Inhibitors of Protein Phosphatase-1 have been shown to slow replication of HIV-1. Inhibitors of PP 1 and their use for treatment or prevention of HIV-1 infections are disclosed.

Abstract: The operation of a power distribution network is modeled. At least one quality of the operation of the power distribution network is measured. The future operational performance of the power distribution network is predicted based at least in part upon the modeling. When the at least one measure of the quality of the operation of the power distribution network or the predicted future operational performance do not meet the predetermined performance criteria, corrective action is taken with respect to the power distribution network.

Abstract: A lighting element is disposed in an array of lighting elements. At the lighting element, a lighting status of at least one neighboring lighting element is sensed. Independent of any other lighting element, a lighting adjustment for the lighting element by applying the sensed lighting status to a predetermined rule is determined. The lighting adjustment is applied to the lighting element to adjust an illumination of the lighting element.

Abstract: An electrical waveform is received over an electrical power line. A plurality of nominal electrical parameters are determined for the electrical power network and the plurality of nominal electrical parameters are associated with a state of the electrical power network in the absence of at least one transitory electrical fault in the network. Subsequently, a plurality of electrical parameters of the electrical waveform are sampled when the at least one transitory electrical fault exists in the network. A plurality of inductances are determined based at least in part upon a comparison of the nominal electrical parameters and the plurality of sampled electrical parameters. The plurality of inductances are representative of inductances present in the network when the at least one transitory electrical fault exists in the network. The plurality of inductances are analyzed to determine a distance and/or direction to the at least one electrical fault.

Abstract: An infrared external photoemissive detector can have an n-p heterojunction comprising an n-type semiconductor layer and a p-layer; the n-layer semiconductor comprising doped silicon embedded with nanoparticles forming Schottky barriers; and the p-layer is a p-type diamond film. The nanoparticles can be about 20-30 atomic percentage metal particles (such as silver) having an average particle size of about 5-10 nm. The p-layer can have a surface layer that has a negative electron affinity. The n-layer can be in the range of about 3 ?m to 10 ?m thick, and preferably about 3 ?m thick. The doped silicon can be doped with elements selected from the list consisting of phosphorus and antimony.

Abstract: A nanothermocouple detector includes a nanowire coupled across two electrodes. The two electrodes are electrically connected to an amplifier. The two electrodes generally have a separation of about five micrometers to about thirty micrometers across which the nanowire is coupled. A focusing element is disposed to admit photons that fall on the focusing element onto the nanowire to heat it. A voltage change across the nanowire caused by the heating of the nanowire by the light is detected by the amplifier. The voltage change corresponds to the energy absorbed from the light by the nanowire. The color of a single photon can be detected using such device. An array of such devices can be used for sensing light on a two-dimensional scale, thereby providing an image showing small variances in the energies of the light impinging upon the detector array.