Patents Assigned to Hydra Biosciences, Inc.
  • Use of TRPA1 antagonists to prevent or treat infections caused by biological-warfare agents
    Patent number: 9260430
    Abstract: Provided are methods for preventing and treating injuries caused by exposure to biological warfare agents. The methods include administering to a subject in need thereof an effective amount of a TRPA1 antagonist or a pharmaceutically acceptable salt thereof. In an embodiment the TRPA1 antagonist is selected from the group consisting of compounds of formula I and compounds of formula II as described herein.
    Type: Grant
    Filed: June 8, 2011
    Date of Patent: February 16, 2016
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventor: Magdalene M. Moran
  • COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1
    Publication number: 20160038499
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: March 9, 2015
    Publication date: February 11, 2016
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Howard Ng, Jianfeng Hang
  • COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO TRPA1
    Publication number: 20160009708
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: February 6, 2015
    Publication date: January 14, 2016
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Xinyuan Wu, Spencer David Kimball, Ping Chen, Ding Zhou, Shaoping Peng
  • COMPOUNDS USEFUL FOR TREATING INJURIES FROM WARFARE AGENTS
    Publication number: 20150352115
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Application
    Filed: December 22, 2014
    Publication date: December 10, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Xinyuan Wu, Spencer David Kimball
  • MODULATORS OF SPERM HYPERMOTILITY AND USES THEREOF
    Publication number: 20150335622
    Abstract: The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.
    Type: Application
    Filed: December 22, 2014
    Publication date: November 26, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Magdalene M. Moran
  • Compounds of modulating TRPV3 function
    Patent number: 9181219
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: November 10, 2015
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventors: Magdalene M. Moran, Jayhong A. Chong, Christopher Fanger, Amy S. Ripka, Glenn R. Larsen, Xiaoguang Zhen, Dennis John Underwood, Manfred Weigele
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20150299225
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: November 14, 2014
    Publication date: October 22, 2015
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • Methods and compositions for treating anxiety
    Patent number: 9139573
    Abstract: Methods of treating a TRPC5 mediated disorder in a subject by administering an effective amount of a TRPC5 antagonist, such as a compound disclosed herein, are described.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: September 22, 2015
    Assignee: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Magdalene M. Moran, Elisha Singer, Timothy Strassmaier, Howard Ng
  • Compounds useful for treating disorders related to TRPA1
    Patent number: 9012465
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: April 21, 2015
    Assignee: Hydra Biosciences, Inc.
    Inventors: Xinyuan Wu, Spencer David Kimball, Ping Chen, Ding Zhou, Shaoping Peng
  • Compositions useful for treating disorders related to TRPA1
    Patent number: 9006207
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: April 14, 2015
    Assignee: Hydra Biosciences, Inc.
    Inventors: Howard Ng, Jianfeng Hang
  • Compounds useful for treating injuries from warfare agents
    Patent number: 8952023
    Abstract: Compounds and compositions for treating disorders related to TRPA1 are described herein.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: February 10, 2015
    Assignee: Hydra Biosciences, Inc.
    Inventors: Xinyuan Wu, Spencer David Kimball
  • Modulators of sperm hypermobility and uses thereof
    Patent number: 8952041
    Abstract: The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: February 10, 2015
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Magdalene M. Moran
  • Compounds for modulating TRPV3 function
    Patent number: 8916550
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: December 23, 2014
    Assignee: Hydra Biosciences, Inc.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, Jr., Magdalene M. Moran, Amy Ripka, Dennis John Underwood, Manfred Weigele, Xiaoguang Zhen, Anu Mahadevan, Peter Meltzer
  • COMPOUNDS AND COMPOSITIONS FOR TREATING CHEMICAL WARFARE AGENT-INDUCED INJURIES
    Publication number: 20140303192
    Abstract: Compounds and compositions for treating injuries caused by exposure to chemical warfare agents are described herein.
    Type: Application
    Filed: March 5, 2014
    Publication date: October 9, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventor: Jayhong A. Chong
  • SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
    Publication number: 20140275071
    Abstract: Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Bertrand L. Chenard, Randall J. Gallaschun
  • SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
    Publication number: 20140275528
    Abstract: Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Bertrand L. Chenard, Randall J. Gallaschun, Spencer David Kimball
  • METHODS AND COMPOSITIONS FOR TREATING PAIN
    Publication number: 20140221401
    Abstract: The present application relates to compounds and methods for treating pain, incontinence and other conditions.
    Type: Application
    Filed: August 14, 2013
    Publication date: August 7, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Magdalene M. Moran, Christopher Fanger, Jayhong A. Chong, Colleen McNamara, Xiaoguang Zhen, Josh Mandel-Brehm
  • COMPOUNDS FOR MODULATING TRPV3 FUNCTION
    Publication number: 20140155417
    Abstract: The present application relates to compounds and methods for treating pain and other conditions related to TRPV3.
    Type: Application
    Filed: August 30, 2013
    Publication date: June 5, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Glenn R. Larsen, William C. Lumma, JR., Anu Mahadevan, Peter Meltzer, Magdalene M. Moran, Amy Ripka, Dennis Underwood, Manfred Weigele, Xiaoguang Zhen
  • Compounds and compositions for treating chemical warfare agent-induced injuries
    Patent number: 8710052
    Abstract: Compounds and compositions for treating injuries caused by exposure to chemical warfare agents are described herein.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: April 29, 2014
    Assignee: Hydra Biosciences, Inc.
    Inventor: Jayhong A. Chong
  • METHODS AND COMPOSITIONS FOR TREATING ANXIETY
    Publication number: 20140100230
    Abstract: Methods of treating a TRPC5 mediated disorder in a subject by administering an effective amount of a TRPC5 antagonist, such as a compound disclosed herein, are described.
    Type: Application
    Filed: December 10, 2013
    Publication date: April 10, 2014
    Applicant: HYDRA BIOSCIENCES, INC.
    Inventors: Jayhong A. Chong, Christopher Fanger, Magdalene M. Moran, Elisha Singer, Timothy Strassmaier, Howard Ng