Abstract: A collection device for examining fecal matter to determine whether a patient is afflicted with parasites includes a particle accumulating plug mounted on an end of a collection tube containing a fecal specimen. The particle accumulating plug includes an inner wall that defines an inverted funnel. A pipetting port is formed through the inner wall at the apex of the inverted funnel allowing the tip of a pipette to enter the port and aspirate the ova or eggs, or other parasite cells, that have separated from the fecal specimen. The conical shape of the inner wall of the plug directs the separated parasite ova or eggs towards the pipetting port and to accumulate within the volume of the funnel of the plug so that a desired volume of fluid containing a concentrated quantity of parasite ova or eggs may be aspirated into the pipette tip through the pipetting port.

Abstract: Systems and methods for use with a biological sample include a microscopy device, a diluent, a sample holder, and one or more of lyophilized cakes comprising artificial particles. The lyophilized cakes and the biological sample are mixed with the diluent in the sample holder to form a solution. The biological sample is imaged with the artificial particles as reference markers using the microscopy device. A settling time of the artificial particles is shorter than or equal to a settling time of the biological sample.

Abstract: The present disclosure is directed to methods and systems for verifying biological analysis devices. The method includes calibrating a hematology device utilizing at least one of a quality control sample or historical patient data, generating diagnostic data associated with a portion of a biological sample with the hematology device, the diagnostic data comprising a first group of attributes associated with the biological sample, identifying whether the first group of attributes is within predetermined parameters, capturing an image of another portion of the biological sample with a microscopy device, identifying a second group of attributes associated with the biological sample based at least in part on the image, and determining one or more verification parameters based on the second group of attributes.

Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.

Abstract: A collection device for examining fecal matter to determine whether a patient is afflicted with parasites includes a particle accumulating plug mounted on an end of a collection tube containing a fecal specimen. The particle accumulating plug includes an inner wall that defines an inverted funnel. A pipetting port is formed through the inner wall at the apex of the inverted funnel allowing the tip of a pipette to enter the port and aspirate the ova or eggs, or other parasite cells, that have separated from the fecal specimen. The conical shape of the inner wall of the plug directs the separated parasite ova or eggs towards the pipetting port and to accumulate within the volume of the funnel of the plug so that a desired volume of fluid containing a concentrated quantity of parasite ova or eggs may be aspirated into the pipette tip through the pipetting port.

Abstract: An example method includes receiving a first order to conduct a first diagnostic test of a sample from a patient, sending the first order to the first diagnostic testing instrument for input into a queue of the first diagnostic testing instrument, receiving alerts and status of the diagnostic test as testing is performed and for indication of completion of the first diagnostic test, sending the alerts and status of the diagnostic test to a second computing device for notice to a technician, receiving an output of the first diagnostic test, generating a recommendation of follow-on testing to perform based on the output of the first diagnostic test, receiving confirmation to perform the follow-on testing, generating a second order to conduct a second diagnostic test of another sample from the patient, and sending the second order to the second diagnostic testing instrument for input into a queue for the second diagnostic testing instrument.

Abstract: An example method includes capturing, via an x-ray machine, a plurality of x-ray images of a patient covering a number of different anatomy of the patient in any order, using a machine learning algorithm to process the plurality of x-ray images for identification of an anatomy in respective x-ray images of the plurality of x-ray images, associating a label with each of the plurality of x-ray images based on the identification of the anatomy, positioning each of the plurality of x-ray images upright based on a preset coordinate scheme for the anatomy, arranging the plurality of x-ray images into a predetermined order based on the species of the patient, and generating and outputting a data file including the plurality of x-ray images in the predetermined order, positioned upright, and labeled.

Abstract: A method of measuring the degree of Z-axis variability in a chemical reagent test slide, which includes the steps of placing a Z-axis measurement fixture on a surface of a gauge block of an optical measurement system having a camera, mounting the chemical reagent test slide on the Z-axis measurement fixture, and positioning the chemical reagent test slide mounted on the Z-axis measurement fixture in optical communication with the camera.

Abstract: Provided herein are compositions and methods for detection of detection and treatment of Mycoplasma haemofelis and Mycoplasma haemocanis.

Abstract: The disclosure relates generally to methods for measuring bacteria in biological samples. More particularly, the disclosure relates to methods for measuring bacteria using an aqueous clearance solution.

Abstract: An example computer-implemented method of increasing veterinary health care compliance includes receiving information indicating that an animal patient concluded a visit at a veterinary practice, in response accessing diagnostic test results for the animal patient, based on the diagnostic test results creating a pet owner profile for an owner of the animal patient, matching the pet owner profile with a stored message and stored information relating to a product associated with recommended treatment for the animal patient, sending an electronic message to a second computing device associated with the owner of the animal patient that includes the stored message and the stored information relating to the product associated with recommended treatment for the animal patient, receiving a report indicating whether the owner of the animal patient obtained the product associated with recommended treatment for the animal patient, and updating the pet owner profile to be indicative of the report.

Abstract: A system and method for retrieving data from a data generating device includes a communication intermediary and an external data storage system. The communication intermediary has a first network interface that is connected to the external data storage system and a second network interface that is connected to the data generating device. The communication intermediary isolates the network communication between the data generating device and second network interface from the network communication between the external storage system and the first network interface, and thereby isolates the data generating device from the external storage system. The communication intermediary monitors the data generating device for newly generated data files, copies the newly generated data files to an internal memory and sends the data files to the external storage system.

Abstract: Apparatuses, systems, and methods for the collection and sampling of agents (including organisms and pathogens) to determine the health of an animal colony. The apparatus includes a perforated housing that incorporates a collection media. The collection media is configured to collect a sample from a target animal, such as a mouse or rat, through the perforations of the housing when the target animal interacts with the perforated housing. The collected sample may include dust, feces, fur, urine, saliva, or other aspect of the target animal's environment.

Abstract: A fecal collection apparatus includes a main body including an insertion end and a removal end opposite the insertion end, the main body defining a main body cavity between the insertion end and the removal end, a sample collection member positionable within the main body cavity through the insertion end, the sample collection member defining a fecal engagement portion for holding a fecal sample and a handle portion spaced apart from the fecal engagement portion, and a plug provided at a removal end of the main body, the plug positionable from a closed position in which the plug restricts fluid from passing from the main body cavity through the removal end, to an open position.

Abstract: A fecal grinder assembly includes a container defining an open interior volume and a plurality of container teeth extending from a bottom wall of the container and within the open interior volume, a grinder slidably positioned within the open interior volume of the container, the grinder including a base and a key extending from the base in a first direction and a plurality of grinder teeth extending from the base in a second direction opposite the first direction, and a collection member including a filter portion and a collection body extending from the filter portion, a keyway extends through the filter and the body for receiving the key of the grinder when the collection member is positioned on the grinder and within the open interior volume of the container.

Abstract: Provided are assays that can provide the percentage of a first mammalian cell population (e.g., human cells) compared to a second mammalian cell population (e.g. mouse cells) in a mixed cell sample. The assays can be used to, for example, evaluate a wide variety of sample types, including humanized mice, humanized organs, passaged cell lines, and passaged tumors. These assays can be offered alone or in combination with, for example, cell line authentication and/or interspecies contamination testing.

Abstract: This invention provides reagents and methods for diagnosing renal disease. Differential levels of inosine metabolite, and proteins: apolipoprotein C-I, apolipoprotein C-II, fibrinogen alpha chain, or fibrinogen A-alpha chain, kininogen, Inter-Alpha Inhibitor H4 (ITIH4), keratin Type I cytoskeletol 10 cystatin A, cystatin B and other polypeptides and fragments thereof provide biomarkers of renal disease and are described herein.

Abstract: An example method includes capturing, via an x-ray machine, a plurality of x-ray images of a patient covering a number of different anatomy of the patient in any order, using a machine learning algorithm to process the plurality of x-ray images for identification of an anatomy in respective x-ray images of the plurality of x-ray images, associating a label with each of the plurality of x-ray images based on the identification of the anatomy, positioning each of the plurality of x-ray images upright based on a preset coordinate scheme for the anatomy, arranging the plurality of x-ray images into a predetermined order based on the species of the patient, and generating and outputting a data file including the plurality of x-ray images in the predetermined order, positioned upright, and labeled.

Abstract: Homogeneous immunoassays that allow for compensation of background signals inherent in samples and reagents. The use of homogeneous immunoassays for the detection of the presence or amount of symmetrical Dimethyl Arginine (SDMA) in biological samples. Reagents and kits for conducting the assays.