Abstract: The present invention relates to the treatment or prevention of skeletal disorders, at particular skeletal diseases, developed by patients that display abnormal increased activation of the fibroblast growth factor receptor 3 (FGFR3), in particular by expression of a constitutively activated mutant of FGFR3.
Type:
Grant
Filed:
October 24, 2019
Date of Patent:
June 14, 2022
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITÉ PARIS CITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, IMAGINE
Inventors:
Laurence Legeai-Mallet, Arnold Munnich, Patricia Busca, Florent Barbault
Abstract: The present invention relates to the treatment or prevention of skeletal disorders, in particular skeletal diseases, developed by patients that display abnormal increased activation of the fibroblast growth factor receptor 3 (FGFR3), in particular by expression of a constitutively activated mutant of FGFR3.
Type:
Grant
Filed:
September 3, 2015
Date of Patent:
April 3, 2018
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PARIS DESCARTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ASSITANCE PUBLIQUE HOPITAUX DE PARIS, UNIVERSITE PARIS DIDEROT-PARIS 7, IMAGINE
Inventors:
Laurence Legeai-Mallet, Arnold Munnich, Patricia Busca, Florent Barbault