Abstract: According to some aspects, a monochromatic x-ray source is provided. The monochromatic x-ray source comprises an electron source configured to generate electrons, a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target, and a secondary target comprising at least one layer of material capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation emitted by the primary target.

Abstract: A device for fixing different-sized base area objects with a vacuum including on a table: first, second, and third vacuum chambers. The third chamber extending the first and second chambers to the entire x direction extension, and the second chamber having parallel, line-forming grooves in the x direction and connected to each other by a first connection channel in the y direction and being released/closed serially relative to the first chamber by a line-switching device. The third chamber includes parallel, column-forming grooves extending in the y direction and connected to each other via a second connection channel in the x direction and being released/closed serially relative to the first chamber by a column-switching device. The third chamber being released/closed serially in the y direction by the line-switching device, in a simultaneous, segmented manner according to the number and positions of the line-forming grooves in correspondence with the second chamber.

Abstract: The inventors demonstrate for the first time the activation of the Hedgehog (HH) signaling pathway in normal and abnormal human mast cells (MCs). These results prompt the inventors to explore the consequence of the inhibition of the HH pathway, especially the canonical pathway, on MC proliferation. They demonstrate that Hedgehog inhibitors inhibit proliferation and induces apoptosis of mast cells. Accordingly the present invention relates to a method of treating a mast cell disease in a patient in need there of comprising administering to the patient a therapeutically effective amount of a Hedgehog inhibitor.

Abstract: A system for producing fragmented video content is provided. The system includes a processing device, a non-transitory data store, and a memory storage device having at least a Manifest Processing Service (MPS) unit stored therein. The MPS unit is configured to generate at least one master manifest and store the master manifest in the non-transitory data store, the master manifest comprising a timing reference for a video fragment of the fragmented video content, wherein the timing reference indicates a temporal boundary of processing for the video fragment.

Abstract: Method for ultrasound determination of a corrected image of a medium, the method comprising: determination of a temporal succession of images (&) of the medium, determination of the movement for each image of the medium, determination of a temporal succession of partial strain images (I??k) based on images of the medium, determination of corrected partial strain images (I??k*) by compensation of said partial strain images (I??k) based on preceding movements, and determination of a corrected strain image (I?k*) by summation of the preceding corrected partial strain images (I??k*).

Abstract: The present invention relates to the treatment or prevention of skeletal disorders, at particular skeletal diseases, developed by patients that display abnormal increased activation of the fibroblast growth factor receptor 3 (FGFR3), in particular by expression of a constitutively activated mutant of FGFR3.

Abstract: A non-limiting exemplary embodiment of a system includes metadata for a plurality of locations, metadata for a plurality of fixtures, metadata for a plurality of campaigns, rules for each location, an apparatus for producing signages for the plurality of locations, and filters for segregating the signages produced into a plurality of kits. Another non-limiting exemplary embodiment of a system includes metadata for a plurality of locations, metadata for a plurality of fixtures, metadata for a plurality of campaigns, rules for each location, filters for segregating the display graphics into a plurality of data packets, transmitting the data packet to the location for which it was prepared, and displaying the graphics contained in the data packet in the location to which it was transmitted.

Abstract: An ultrasound system comprising a probe adapted for emitting and receiving ultrasound waves inside a medium, and a processing unit connected to said probe and adapted for processing signals from the probe. The probe is configured so as to behave as a Fresnel lens for focusing the ultrasound waves. The processing unit analyses signals from the probe for sensing the medium at a plurality of focal points.

Abstract: A playout system for providing playout of fragmented video content is provided. The system includes a non-transitory data store and a processor. The processor is configured to playout content for video origination using a fragmented format. The processor can receive a playlist and generate a plurality of video fragments from source content. A transcoder can process video fragments based on one or more program scheduling requirements from the playlist to generate new video fragments. A manifest is updated to reference the new video fragments. The process can output a video stream based on the new video fragments.

Abstract: A device for analysing a wavefront may be connected to a fluorescence microscopy imaging system with optical sectioning, equipped with a microscope objective including a pupil in a pupil plane, the analysis device including a two-dimensional detector including a detection plane; a two-dimensional arrangement of microlenses, arranged in an analysis plane, each microlens forming, on the detection plane, when the analysis device is connected to the microscopic imaging system, an image of an object situated in a focal plane of the microscope objective, with a given analysis field; an optical relay system optically conjugating the analysis plane and the pupil plane; a field diaphragm positioned in a plane optically conjugated with the plane of detection, and defining said analysis field; a processing unit that determines, based on the set of images formed by the microlenses, a two-dimensional map of a characteristic parameter of the wavefront in said analysis plane.

Abstract: An electrically conductive textile containing graphene that undergoes a change in electrical resistance when deformed.

Abstract: A geosynthetic sensor that incorporates an arrangement of a first layer of lengths of electrically conductive geosynthetic and a second layer of lengths of electrically conductive geosynthetic where each said length undergoes a change in electrical resistance or capacitance when subject to changes in any one or more of: pressure; strain; water content; or temperature.

Abstract: Absorbent microstructure panels are described herein. An example filter device includes a plurality of microstructure panels each having a front surface and a back surface, and a plurality of capillary ridges protruding from the front surface. The plurality of capillary ridges are each spaced apart from one another. The plurality of microstructure panels form an absorbent microstructure array by layering the plurality of microstructure panels together such that the plurality of capillary ridges of one microstructure panel contacts the back surface of an adjacent microstructure panel to create capillary tubes that draw fluid into the absorbent microstructure array.

Abstract: A system for producing fragmented video content is provided. The system includes a processing device, a non-transitory data store, and a memory storage device having at least a Manifest Processing Service (MPS) unit stored therein. The MPS unit is configured to generate at least one master manifest and store the master manifest in the non-transitory data store, the master manifest comprising a timing reference for a video fragment of the fragmented video content, wherein the timing reference indicates a temporal boundary of processing for the video fragment.

Abstract: The invention relates to a probe (110, 210, 310, 410, 510) which has a sealed cooling chamber (140, 240, 340, 440, 540) arranged within a casing (112, 212, 312, 412, 512) of the probe. An interface unit (124, 224, 324, 424, 524) of the probe is at least partially arranged within the cooling chamber or in contact with the cooling chamber. The cooling chamber is at least partially filled with a heat transfer liquid (142, 242, 342, 442, 542).

Abstract: A method for estimating an ultrasonic attenuation parameter of a region in a medium includes a transmission step in which at least one pulse is transmitted in the medium by a transducer, and a reception step in which data is acquired by a transducer in response to the pulse. The method includes a processing step in which the data is processed by the processing unit for providing backscattered acquisition data of the region, and a function determination step in which an auto-correlation function of the backscattered acquisition data is determined which is a function of depth in the spatio-temporal domain, the autocorrelation function being determined at a lag of zero. The method includes an attenuation estimation step in which an ultrasonic attenuation parameter is estimated based on said auto-correlation function. The method is implemented by a processing unit associated to at least one ultrasound transducer.

Abstract: A method (40) for determining a target speed of sound inside a target region of a medium using an ultrasound imaging system. The method comprises the steps of determining a position of an interface in the medium, determining a first speed of sound of an intermediate region above the interface, and determining a target speed of sound inside a target region below the interface based on at least some of sensed signals and taking into account the position of the interface and the first speed of sound.

Abstract: According to some aspects, a monochromatic x-ray source is provided. The monochromatic x-ray source comprises an electron source configured to generate electrons, a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target, and a secondary target comprising at least one layer of material capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation emitted by the primary target.

Abstract: A substance having innate immune stimulating activity is a polysaccharide, which contains 25 to 50 parts by mole of galacturonic acid, 15 to 50 parts by mole of galactose, 0 to 7 parts by mole of glucose, 0 to 30 parts by mole of arabinose, 0 to 6 parts by mole of xylose, and 3 to 15 parts by mole of rhamnose as constituent sugars. The polysaccharide has a polygalacturonic acid chain having ?-1,4-linked galacturonic acid as a main chain. An innate immune stimulant can include the polysaccharide as an active component, which can be included in a food or drink.

Abstract: According to some aspects, a carrier configured for use with a broadband x-ray source comprising an electron source and a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target is provided. The carrier comprising a housing configured to be removeably coupled to the broadband x-ray source and configured to accommodate a secondary target capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation, the housing comprising a transmissive portion configured to allow broadband x-ray radiation to be transmitted to the secondary target when present, and a blocking portion configured to absorb broadband x-ray radiation.