Abstract: Method for ultrasonic characterization of a medium, comprising generating a series of incident ultrasonic waves, generating an experimental reflection matrix Rui(t) defined between the emission basis (i) as input and a reception basis (u) as output, and determining a focused reflection matrix RFoc(rin, rout, ?t) of the medium between an input virtual transducer (TVin) calculated based on a focusing as input to the experimental reflection matrix and an output virtual transducer (TVout) calculated based on a focusing as output from the experimental reflection matrix, the responses of the output virtual transducer (TVout) being obtained at a time instant that is shifted by an additional delay ?t relative to a time instant of the responses of the input virtual transducer (TVin).

Abstract: The invention relates to an in vitro method to generate T cell progenitors, comprising the step of culturing CD34+ cells in a medium containing TNF-alpha and/or an antagonist of the Aryl hydrocarbon/Dioxin receptor, in particular StemRegenin 1 (SR1), in presence of a Notch ligand and optionally a fibronectin fragment.

Abstract: Method for ultrasonic characterization of a medium, comprising generating a series of incident ultrasonic waves, generating an experimental reflection matrix Rui(t) defined between the emission basis (i) as input and a reception basis (u) as output, and determining a focused reflection matrix RFoc(rin, rout, ?t) of the medium between an input virtual transducer (TVin) calculated based on a focusing as input to the experimental reflection matrix and an output virtual transducer (TVout) calculated based on a focusing as output from the experimental reflection matrix, the responses of the output virtual transducer (TVout) being obtained at a time instant that is shifted by an additional delay ?t relative to a time instant of the responses of the input virtual transducer (TVin).

Abstract: According to some aspects, a monochromatic x-ray source is provided. The monochromatic x-ray source comprises an electron source configured to generate electrons, a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target, and a secondary target comprising at least one layer of material capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation emitted by the primary target.

Abstract: The present invention provides a pharmaceutical formulation comprising a therapeutically effective amount of a polypeptide corresponding to SEQ ID No, 2 and uses thereof for treating at least one of diabetes, hyperglycemia, hypercholesterolemia, and hypertension in a subject.

Abstract: The present description relates, according to one aspect, to a high-peak-power laser pulse generation system (10), comprising at least one first light source (101) for emitting first laser pulses (IL), a fiber device (110) for transporting said first laser pulses, comprising at least one first multimode fiber with a single core designed to receive said first laser pulses, and a module (102) for temporally shaping said first laser pulses, arranged upstream of the fiber device, configured so as to reduce the power spectral density of said pulses by reducing the temporal coherence.

Abstract: The present invention relates to an in vitro method of culturing a segmented filamentous bacterium strain, comprising co-culturing said segmented filamentous bacterium strain with a eukaryotic host cell, wherein the culture is performed at an O2 level inferior to 5% in a rich tissue culture liquid medium containing bacterial medium components including iron. The present invention also relates to methods for genetically modifying a segmented filamentous bacterium strain comprising a step a culturing the strain in vitro.

Abstract: An ultrasound system comprising a probe adapted for emitting and receiving ultrasound waves inside a medium, and a processing unit connected to said probe and adapted for processing signals from the probe. The probe is configured so as to behave as a Fresnel lens for focusing the ultrasound waves. The processing unit analyses signals from the probe for sensing the medium at a plurality of focal points.

Abstract: Embodiments herein are directed to a handle assembly for releasable coupling to an exterior surface of a tray that is configured to retain a fluid is provided. The handle assembly includes a base member and a quick-release attachment assembly. The base member includes an elongated member that has a distal end, an opposite proximal end and a planar portion having an outer surface. The planar portion is positioned to extend from the proximal end and above the proximal end of the elongated member in a vertical direction. The quick-release attachment assembly has an interior surface and an opposite exterior surface. The interior surface is coupled to and extending from the outer surface of the planar portion of the elongated member. The exterior surface of the quick-release attachment assembly is adapted to releasable couple the elongated member to the exterior surface of the tray.

Abstract: A paintbrush holding apparatus for a paint tray that includes a trough. A brush holding body is attached to the trough. The brush holding body includes an inner portion separated from an outer portion. The inner portion includes a magnetic portion formed thereon. The magnetic portion is structured to hold a ferrule of a brush and maintain the paintbrush above or within the tray. The outer portion includes a magnetic portion formed thereon. The magnetic portion is structured to hold a ferrule of a brush and maintain the paintbrush above or within the trough. An attachment structure is attached to the brush holding body. The attachment structure grasps a wall of the paint tray. The brush holding body is positioned within a volume of the paint tray and the trough is positioned outboard of the volume of the paint tray.

Abstract: Provided herein is a polypeptide or formulation comprising a polypeptide for use in the treatment of a disease characterized by endothelial dysfunction, wherein the polypeptide or a fragment thereof comprising an amino acid comprising an amino acid sequence having at least 55% sequence identity to the amino acid sequence set forth in SEQ ID NO: 1, 2, 3, or 4. Also provided are methods and uses relating to the same.

Abstract: The multi-scale scanning imaging system (200) of the retina comprises according to an example a lighting and detection module (210) configured for emitting a lighting beam and for detecting a beam reemitted by the retina, a first scanning module (231) of the lighting beam and the reemitted beam, a first optical path, referred to as a “wide field” path, and a second optical path, referred to as a “small field” path, for focusing the lighting beam on the retina and for receiving the beam reemitted by the retina. The “wide field” path comprises a first optical system (205, 201) configured to conjugate a plane located near a plane of rotation of the scanning module and the plane (17) of the entrance pupil of the eye (10).

Abstract: Examples relate to a method for processing beamformed data of a medium. The beamformed data includes a first set of beamformed data associated with a first spatial region and a second set of beamformed data associated with a second spatial region, and the method includes estimating the clutter caused by the second spatial region at the first set.

Abstract: A novel and advantageous packaging system for card packaging system is provided. The card packaging system can hold a card and a promotional item and can display the serial number of the card while keeping the personal identification number for the card hidden. The card packaging system can be easily hung from a merchandise display. The card packaging system may include a card unit comprising a card, a hanger, and a stem, the stem being positioned between the card and the hanger, wherein the card may be separate from the hanger and the stem. The card packaging system may further comprise a case for receiving the card unit, the case including a slot for receiving the stem such that the card is positioned in the case and the hanger extends outwardly from the case.

Abstract: A shear wave elastography method for imaging an observation field in an anisotropic medium, including an initial ultrasonic acquisition step during which initial physical parameters are acquired in at least one region of interest; a spatial characterization step during which a set of spatial characteristics of the anisotropic medium is determined on the basis of the initial physical parameter; an excitation substep during which an shear wave is generated inside the anisotropic medium on the basis of the set of spatial characteristics; and an observation substep during which the propagation of the shear wave is observed simultaneously at a multitude of points in the observation field.

Abstract: A method may include controlling alignment of the eye in an ophthalmological imaging device that includes an imaging system with a given optical axis. The method may include the formation, on a two-dimensional detection plane, of an image of an element located in a plane of the pupil of the eye. The method further includes the determination of a lateral position of the pupil of the eye with respect to a point of origin of a reference frame of the imaging system, on the basis of the position of the image. The method further includes the analysis of a state of focus of the image. The method further includes the determination of an axial position of the pupil of the eye with respect to the point of origin of the reference frame of the imaging system, on the basis of the analysis of the state of focus.

Abstract: The present invention relates to methods for performing antisense oligonucleotide-mediated exon skipping in the retina of a subject in need thereof. In particular, the present invention relates to a method for performing antisense oligonucleotide-mediated exon skipping in a retina cell of a subject comprising the step of injecting into the vitreous of the subject an amount of the antisense oligonucleotide.

Abstract: A topical composition including erlotinib and a pharmaceutically acceptable excipient for use in the treatment of a keratoderma in a child, preferably a palmoplantar keratoderma (PPK), wherein the composition is topically administered. The composition may further include a penetration enhancer. The treated subject may be younger than three years old. Also, woven or non-woven fabric support including erlotinib and to dressings, patches, gloves and socks having the support useful in the treatment of a PPK.

Abstract: A textile with an electrically conductive first side and an electrically conductive second side where the two sides are separated by an electrically insulating part of the textile and where the electrically conductivity is provided by a graphene coating on the respective sides and where a capacitance can be formed between the respective conductive sides.