Abstract: A substance having innate immune stimulating activity is a polysaccharide, which contains 25 to 50 parts by mole of galacturonic acid, 15 to 50 parts by mole of galactose, 0 to 7 parts by mole of glucose, 0 to 30 parts by mole of arabinose, 0 to 6 parts by mole of xylose, and 3 to 15 parts by mole of rhamnose as constituent sugars. The polysaccharide has a polygalacturonic acid chain having ?-1,4-linked galacturonic acid as a main chain. An innate immune stimulant can include the polysaccharide as an active component, which can be included in a food or drink.

Abstract: The present invention relates to the use of hydroxycarbamide (HC) for reducing and/or delaying the extension of capillary nonperfusion, a cause of irreparable visual impairment in patients suffering from central retinal vein occlusion (CRVO). This is the first systemic treatment which makes it possible to reduce retinal ischemic complications in patients in whom (CRVO) has been recently diagnosed and is consequently in a rapidly progressive phase. Given the low toxicity of HC evaluated on a large scale in children and adults in the context of other diseases for decades, the results of the present study open up a new therapeutic approach in the treatment of CRVO.

Abstract: A method of applying labels to a store shelf in a retail environment. The method includes applying labels with adhesive strips applied to a bottom surface of each label and a top laminate layer with a release coating applied to the top surface of each label. The labels in the pad are sequenced according to a store's planogram.

Abstract: A non-limiting exemplary embodiment of a system includes metadata for a plurality of locations, metadata for a plurality of fixtures, metadata for a plurality of campaigns, rules for each location, an apparatus for producing signages for the plurality of locations, and filters for segregating the signages produced into a plurality of kits. Another non-limiting exemplary embodiment of a system includes metadata for a plurality of locations, metadata for a plurality of fixtures, metadata for a plurality of campaigns, rules for each location, filters for segregating the display graphics into a plurality of data packets, transmitting the data packet to the location for which it was prepared, and displaying the graphics contained in the data packet in the location to which it was transmitted.

Abstract: The present invention provides a composition comprising a therapeutically effective amount of a polypeptide, peptide, or analog corresponding to one or more of SEQ ID NO(s) 1, 2, 3 or 4, and or more of a pharmaceutically acceptable carrier, pharmaceutically acceptable diluent, and/or pharmaceutically acceptable excipient. The polypeptide therapeutic of the present invention may be formulated for administration to a subject in need of treatment as an oral formulation, a parenteral formulation, a topical formulation, an aqueous formulation, a solid formulation, a lyophilized formulation, or a trans-dermal formulation. Also disclosed is a method for treating at least one of diabetes, and/or hyperglycemia, and/or hypercholesterolemia, and/or hypertension in a subject, comprising: administering to the subject a polypeptide of the invention or formulation of the invention.

Abstract: Embodiments of systems, program products, and methods to manage content and distribution of media are provided. An embodiment of a system, for example, can include a communication network for transmitting media files, a content management server having a processor and memory coupled to the processor, a database accessible to the processor of the content management server and including media files associated with metadata records, a plurality of content management developer computers to provide content management developers with online access over the communication network to the media files and associated metadata records to thereby edit the metadata records, a plurality of user computers accessible to the communication network to provide the users with access to the media files over the communication network to thereby view and edit at least portions of respective metadata records.

Abstract: A method for evaluating the quality of the measurement of an optical wavefront, said measurement being obtained by means of a wavefront analyzer by direct measurement, the method comprising: the acquisition (10) of an optoelectronic signal for the measurement of the wavefront by means of a wavefront sensor, said sensor comprising a two-dimensional detector; the determination (11) on the basis of said optoelectronic signal of at least one parameter characteristic of a parasitic component of the optoelectronic signal; the evaluation (12) of a quality factor of the measurement of the wavefront as a function of said at least one parameter characteristic of the parasitic component of the signal; the display (13) to a user of a level of quality of the measurement as a function of said quality factor.

Abstract: Systems and methods for determining trust levels for components of a computing application including a development framework, a trust matrix, a trust level calculation module, a visual design subsystem, and a deployment subsystem, where trust levels are associated with components, combinations of components, graphs, and blueprints, where trust levels relate to categories of use.

Abstract: A method for delivering media content includes receiving a request identifying a requested media file. The method also includes, in response to receiving the request, accessing the requested media file. The requested media file includes media content in a first format. The method further includes generating a modified media file based on the requested media file. The modified media file includes media content in a second format. Additionally, the method includes generating an auxiliary file associated with the modified media file. The auxiliary file includes a plurality of content records associated with different portions of the media content in the modified media file and indicating a location of the associated portion. Each content record includes information to facilitate transmission of the associated portion of the media content to a remote client prior to the modified media file being completely generated.

Abstract: A method comprising receiving a request for media content from a client, accessing a plurality of source files associated with the requested media content based on the request, wherein the plurality of source files comprise the media content in one or more source formats, and generating a portion of a plurality of target files based on the plurality of source files. The method further comprising generating an auxiliary file for the generated portion of the plurality of target files to facilitate transmission of the generated portion of the plurality of target files to the client and transmitting to the client as a seamless media transmission the generated portion of the plurality of target files, wherein the portion of the plurality of target files are transmitted to the client simultaneously with generation of another portion of the plurality of target files and a corresponding auxiliary file.

Abstract: A system includes a first buffer that stores first media packets therein received from a first media stream. A second buffer stores second media packets therein received from a second media stream. The first media stream and the second media stream include redundant media content. A combiner reads media packets from each of the first and second buffers, and the combiner discards a given duplicate media packet read from one of the first or second buffers that has been identified as being identical to another of the media packets read from the other of the buffers based on analysis of a predetermined identifier in each of the media packets read from the first and second buffers. The combiner provides an output stream of media packets that includes only one of the identical media packets read from the first and second buffers.

Abstract: The present invention relates to an in vitro method of culturing a segmented filamentous bacterium strain, comprising co-culturing said segmented filamentous bacterium strain with a eukaryotic host cell, wherein the culture is performed at an O2 level inferior to 5% in a rich tissue culture liquid medium containing bacterial medium components including iron. The present invention also relates to methods for genetically modifying a segmented filamentous bacterium strain comprising a step a culturing the strain in vitro.

Abstract: Embodiments of systems, program products, and methods to manage content and distribution of media are provided. An embodiment of a system, for example, can include a communication network for transmitting media files, a content management server having a processor and memory coupled to the processor, a database accessible to the processor of the content management server and including media files associated with metadata records, a plurality of content management developer computers to provide content management developers with online access over the communication network to the media files and associated metadata records to thereby edit the metadata records, a plurality of user computers accessible to the communication network to provide the users with access to the media files over the communication network to thereby view and edit at least portions of respective metadata records.

Abstract: A material for decorative wrap including a sheet of non-corrugated material having a first side, a second side, a first edge, and a second edge; a plurality of scores formed into the first side extending from the first edge to the second edge; and a plurality of scores formed into the second side extending from the first edge to the second edge. The plurality of scores formed into the first side and the plurality of scores formed into the second side may alternate such that every other score is formed into the first side and the remaining scores are formed into the second side. Each score formed into the first and second sides may extend substantially perpendicular to at least one of the first and second edges.

Abstract: Systems and methods for dynamic development and/or management of computing applications including a development framework, a visual design subsystem, a deployment subsystem, and a distributed ledger, where at runtime the deployment subsystem is operable to dynamically deploy a computing application realized by a blueprint by sending a request at runtime for graphs and components instantiated by the blueprint, and the distributed ledger is operable to store a set of components and associating each component with a digital certificate.

Abstract: Systems and methods for dynamic development and/or deployment of computing applications including a development framework, a visual design subsystem, and a deployment subsystem, where at runtime the deployment subsystem is operable to dynamically deploy a computing application realized by a blueprint by sending a request at runtime for graphs and components instantiated by the blueprint.

Abstract: An electrically conductive geotextile incorporating graphene and a method of using conductive properties in same to detect anomalies in said textile.

Abstract: A hold-down clamping apparatus comprising a hold-down clamp with body having a top lip and pair of guide legs disposed between a central screw in the body and a support having holes in vertical alignment with the legs and the screw for securing and holding down a sheet material for processing. The screw is threaded through the support screw hole as the legs are inserted within support holes until the top lips contacts the sheet material to hold down the material and to prevent twisting of the hold-down clamp. Supports with clamps may be fastened to tools or supports. In one embodiment, the support has a grid of holes for securing a plurality of materials with hold-down clamps. In another embodiment, the hold-down clamp comprises a top lip and a guide beam slotted in a support and secured.

Abstract: Methods and apparatus are provided for licensing service providers to process video, audio and/or multimedia content using a video processing device. A license key indicative of a license for an amount of bandwidth is generated. The license key is used at the video processing device to enforce the license based on whether there is sufficient licensed bandwidth available to accommodate a newly created output transport stream. If there is sufficient licensed bandwidth available, processing of the newly created output transport stream is allowed. If there is insufficient licensed bandwidth available, processing of the newly created output transport stream is denied. The service providers are charged a license fee to use the video processing equipment based on the licensed bandwidth.

Abstract: Multiple staged filters are provided herein. A filter may include a plurality of panels that each include a filtering front surface and a flat back surface, the filtering front surface having a first row of vertically extending protrusions spaced apart from one another to form vertical channels, a second row of vertically extending protrusions spaced apart from one another to form vertical channels, and one or more rows of filtering protrusions, where the one or more rows are vertically spaced apart from one another and extending between the first and second rows of vertically extending protrusions. Further, each row of filtering protrusions may include filtering protrusions that are spaced from one another to form filter channels having a size that is configured to receive and retain objects of a given size.