Abstract: An optical tracking device is used to track a target object. An outer surface of the target object is divided into a first region and a second region adjacent to each other, and a marker is disposed on the first region. The optical tracking device includes an optical sensor and an operation processor. The optical sensor has auto exposure function and is adapted to acquire a detection image containing at least one of the first region and the second region. The operation processor is electrically connected to the optical sensor and adapted to analyze variation of an exposure parameter of the auto exposure function for determining whether the first region is appeared in the detection image, so as to acquire an operation datum of the target object.

Abstract: Near infrared imaging is highly complementary to color imaging having a wide range of applications. For example, in health applications, the near infrared can provide biomolecular information on tissue that is not apparent under visual examination nor from the inspection of color images of tissue. Thus, there is utility in viewing both visible color and near infrared images in combination. Described herein are methods to perform visible and near infrared imaging as well as hybrid visible color and near infrared imaging with a single conventional color filter array RGB sensor. The methods automatically provide spatially co-registered color and near infrared images and the methods can be used as the basis for a multispectral or hyperspectral imaging system.

Abstract: A movement detection method, applied to a navigation input device with a navigation pattern comprising a center pattern and a radial pattern. The movement detection method comprises: (a) capturing a sensing image comprising a center pattern image and at least portion of a radial pattern image by an image sensor, wherein the center pattern image corresponds to the center pattern and the radial pattern image corresponding to the radial pattern; (b) computing a translation of the navigation input device according to shift of the center pattern image; and (c) computing a rotation angle of the navigation input device according to a first pattern relation between the center pattern image and a first portion of the radial pattern image. The translation and the rotation angle can be precisely and sensitively detected even if the joystick device is miniaturized, since the translation and the rotation angle are computed according to the navigation pattern.

Abstract: In one embodiment, the disclosure relates to a probe that a cylindrical marker band defining an inner surface, an outer surface, a first end and a second end and having a band length, the inner surface defining a marker band bore, the cylindrical marker band includes a radiopaque material; a molded unitary lens defining an elongate optical fiber receiving section having a fiber section length and a beam directing surface, wherein the fiber section length and the band length overlap along an overlap distance; and an optical fiber, wherein a first section of the optical fiber is disposed in the optical fiber receiving section, wherein a portion of the first section of the optical fiber is disposed within the marker band bore.

Abstract: The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

Abstract: The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.

Abstract: The present invention generally relates to novel synthetic methods, systems, kits, salts, and precursors useful in medical imaging. In some embodiments, the present invention provides compositions comprising an imaging agent precursor, which may be formed using the synthetic methods described herein. An imaging agent may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18F. In some cases, an imaging agent including salt forms (e.g., ascorbate salt) may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.

Abstract: An optical sensor, comprising: a sensor array, comprising a bright region with at least one bright pixel and comprising a dark region with at least one dark pixel, wherein the dark pixel generates a sensing signal that is non-relevant to light emitted to the sensor array; a power noise detection circuit, configured to compute a power noise level of the sensing signal from the dark pixel; and a power noise compensation circuit, configured to control the optical sensor to perform a power noise compensation operation according to the power noise level. A related power noise reduction method is also disclosed. Based on the present invention, the power noise of the optical sensor can be reduced without increasing the power consumption, and the power noise for a low switch frequency can also be improved.

Abstract: Provided herein are improved methods for preparing phospholipid formulations including phospholipid UCA formulations.

Abstract: Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit increased stability, decreased NE release (thereby reducing side effects), improved quantitative data, and/or high affinity for VMAT over prior radiotracers. Methods of using the compounds to image cardiac innervation are also provided. In some instances the compounds are developed by derivatizing certain compounds with 18F in a variety of positions: aryl, alkyl, a keto, benzylic, beta-alkylethers, gamma-propylalkylethers and beta-proplylalkylethers. Alternatively or additionally, a methyl group a is added to the amine, and/or the catechol functionality is either eliminated or masked as a way of making these compounds more stable.

Abstract: A fluorescence microscopy inspection system includes light sources able to emit light that causes a specimen to fluoresce and light that does not cause a specimen to fluoresce. The emitted light is directed through one or more filters and objective channels towards a specimen. A ring of lights projects light at the specimen at an oblique angle through a darkfield channel. One of the filters may modify the light to match a predetermined bandgap energy associated with the specimen and another filter may filter wavelengths of light reflected from the specimen and to a camera. The camera may produce an image from the received light and specimen classification and feature analysis may be performed on the image.

Abstract: The invention provides, inter alia, improved lipid formulations used to generate lipid-encapsulated gas microspheres, and methods of their use.

Abstract: A computing system receives, from an image sensor, at least two images of a specimen positioned on a specimen stage of a microscope system. The computing system provides the at least two images to an autofocus model for detecting at least one distances to a focal plane of the specimen. The computing system identifies, via the autofocus model, the at least one distance to the focal plane of the specimen. Based on the identifying, the computing system automatically adjusts a position of the specimen stage with respect to an objective lens of the microscope system.

Abstract: Described are transducer assemblies and imaging devices comprising: a microelectromechanical systems (MEMS) die including a plurality of piezoelectric elements; a complementary metal-oxide-semiconductor (CMOS) die electrically coupled to the MEMS die by a first plurality of bumps and including at least one circuit for controlling the plurality of piezoelectric elements; and a package secured to the CMOS die by an adhesive layer and electrically connected to the CMOS die.

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

Abstract: A computing system identifies a trajectory example generated by a human operator. The trajectory example includes trajectory information of the human operator while performing a task to be learned by a control system of the computing system. Based on the trajectory example, the computing system trains the control system to perform the task exemplified in the trajectory example. Training the control system includes generating an output trajectory of a robot performing the task. The computing system identifies an updated trajectory example generated by the human operator based on the trajectory example and the output trajectory of the robot performing the task. Based on the updated trajectory example, the computing system continues to train the control system to perform the task exemplified in the updated trajectory example.

Abstract: Disclosed herein are systems and methods for visualizing a target anatomical site of a patient using one or more imagers. The method can include placing multiple imagers on multiple locations at an anatomical site. The method can further include generating separate image data sets from the multiple images and combining the image data sets to generate a volumetric imaging data of the anatomical site. The volumetric imaging data can include all anatomical features within the target anatomical site. A visualization system for medical imaging can include transducers on the imagers to visualize the target anatomical site. The system can further include a processor to combine the image data sets to generate the volumetric imaging data set. The system can further include a display device to display the volumetric imaging data set.

Abstract: A smart ring with a physiological feature detecting method is applied to a target object. The smart ring includes a pressure sensor and an operation processor. The pressure sensor is adapted to detect a pressure value of the target object applied for the smart ring. The operation processor is electrically connected with the pressure sensor, and adapted to compare the pressure value with a preset condition and determine a behavior of the target object according to a comparison result of the pressure value and the preset condition for generating a related operation command.

Abstract: A method and system detects cerebral amyloid angiopathy (CAA) condition of a subject by capturing multiple images of the subject's retina, processing the images to detect any retinal hemorrhage, retinal vessel tortuosity, and retinal edema, to predict the likelihood of CAA.

Abstract: An optical decoding device, comprising: an image sensor, configured to sense first sensing images and second sensing images; a processing circuit, configured to determine a relative movement between the optical decoding device and an object according to the first sensing images; and a decoding device, configured to decode the second sensing images in a first mode to generate a decoding result and does not decode the second sensing images in a second mode. The decoding device switches between the first mode and the second mode according to the relative movement, thus can save power. A barcode, a color code which can be provided on a curved surface and an invisible code are also disclosed. An electrical cigarette lighter using the optical decoding device to provide heat is also disclosed.