Abstract: An endoscopic illumination sleeve includes a housing holding a plurality of LED light sources (LEDs) for providing light to respective light fibers, the housing forming a chamber sized for encircling an endoscope shaft. A flexible sleeve is coupled to the housing and including the light fibers, the flexible sleeve adapted to be placed around the endoscope shaft such that a distal end of the sleeve is positioned toward the distal end of the endoscope shaft and the light fibers extend from the housing to the distal end to illuminate a scene. The flexible sleeve and housing are adapted to be secured around the endoscope in a working position for a medical procedure, and to be removable therefrom. A kit may include multiple sleeves providing different lighting capabilities.

Abstract: A system and method for generating a training data set for training a machine learning model to detect defects in specimens is described herein. A computing system cause presentation of an image on a device of a user. The image includes at least one defect on an example specimen. The computing system receives an annotated image from the user. The user annotated the image using an input via the device. The input includes a first indication of a location of the defect and a second indication of a class corresponding to the defect. The computing system adjusts the annotated image to standardize the input based on an error profile of the user and the class corresponding to the defect. The computing system uploads the annotated image for training the machine learning model.

Abstract: A computer apparatus and method for identifying and visualizing tumors in a histological image and measuring a tumor margin are provided. A CNN is used to classify pixels in the image according to whether they are determined to relate to nontumorous tissue, or one or more classes for tumorous tissue. Segmentation is carried out based on the CNN results to generate a mask that marks areas occupied by individual tumors. Summary statistics for each tumor are computed and supplied to a filter which edits the segmentation mask by filtering out tumors deemed to be insignificant. Optionally, the tumors that pass the filter may be ranked according to the summary statistics, for example in order of clinical relevance or by a sensible order of review for a pathologist. A visualization application can then display the histological image having regard to the segmentation mask, summary statistics and/or ranking. Tumor masses extracted by resection are painted with an ink to highlight its surface region.

Abstract: An optical sensing system comprising a first optical sensor. The first optical sensor comprises: a first pixel array; and a first light gating layer, configured to receive first input light and to provide first receiving light to the first pixel array, to make the first optical sensor has at least two different light sensitivities.

Abstract: An electronic device comprising: a clock pin; at least one data pin; a storage device, configured to store at least one program; a processing circuit, coupled to the data pin. A device ID setting method is performed when the processing circuit executes the program stored in the storage device. The device ID setting method comprises; (a) recording connections between pins of a first electronic device and pins of the electronic device by the electronic device, wherein the first electronic device comprises at least one data pin; and (b) applying the connections between the pins of the first electronic device and the pins of the electronic device as a device ID of the first electronic device by the electronic device.

Abstract: A pointing method, applied to a pointing device comprising a processing circuit, comprising: (a) receiving input delta by the processing circuit, wherein the input delta indicates supposed movement of the pointing device; (b) adjusting the input delta to generate output delta by the processing circuit, wherein the input delta has a first magnitude and the output delta has a second magnitude, wherein the second magnitude is smaller than or equal to the first magnitude; and (c) output the output delta by the processing circuit.

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

Abstract: A method of identifying a false alarm of an optical motion sensor including a plurality of pixel units, includes: receiving pixel values of a testing set of pixel units selected from the plurality of pixel units, and a number of pixels of the testing set is smaller than a number of the plurality of pixel units; and performing a background adjustment operation according to the pixel values of the testing set of pixel units.

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.

Abstract: An object position determining system comprising: at least one light source, configured to emit light; at least one optical sensor, configured to sense optical data generated based on reflected light of the light; and a processing circuit, configured to compute distance information between the optical sensor and an object which generates the reflected light. The processing circuit further determines a position of the object according to the distance information.

Abstract: The present disclosure provides systems and methods for dynamically visualizing the delivery of a device within a vessel by correlating at least one first extraluminal image with second extraluminal images. The extraluminal images may be correlated based on motion features, without the use of other sensors or timestamps. The first extraluminal image may be a high dose contrast x-ray angiogram (“XA”) and the second extraluminal images may be low dose contrast XAs. The high dose contrast XA may be used to generate a vessel map. The low dose contrast XAs may be taken during the delivery of a device, such as a balloon, stent, probe, or the like. Correlating the high dose XA and low dose XA based on motion features allows for the vessel map to be overlaid on the low dose XA to provide the physician visualization of where the device is within the vessel tree in real time.

Abstract: A stacked structure formed of two active element layers includes: a first substrate; a first conductive surface including a first active region; a second substrate; a second conductive surface including a second active region; a compression space between the first active region of the first conductive surface and the second substrate; an elastic layer formed on the first active region of the first conductive surface or on an exposed surface of the second substrate, and including a plurality of elastic nodules compressed by relative movement of the first conductive surface and the second conductive surface toward each other in response to a voltage difference, or in response to an external force; and a first solid binding edge formed at one side of the first active region of the first conductive surface and the second conductive surface, and coupled to the first active region and the second substrate.

Abstract: A clock generation circuit, comprising a first RC circuit, a first switch, a second RC circuit, a second switch, a comparator and a logic circuit. The first RC circuit comprises a first capacitor, coupled to a first predetermined voltage level and a second predetermined voltage level. The second RC circuit comprises a second capacitor, coupled to the first switch. The comparator comprises: a first input terminal, coupled to the second RC circuit and the second switch; a second input terminal, configured to receive a reference voltage level; and an output terminal, coupled to a control terminal of the first switch and a control terminal of the second switch. The logic circuit is coupled to the output terminal of the comparator, configured to generate a clock signal. In one embodiment, the clock generation circuit is applied to an image sensor.

Abstract: Methods and systems are provided for extracting cardiac frequency angiographic phenomena for an unconstrained vascular object from an angiographic study. In one example, a computer may obtain a series of angiographic image frames obtained at a rate faster than cardiac frequency. Each image frame may comprise a plurality of pixels, and each pixel may have a corresponding intensity. The computer may apply an optical flow technique to the angiographic image frames to generate a plurality of paths corresponding to a displacement of respective pixels from image frame to image frame. The computer may further generate a spatiotemporal reconstruction of cardiac frequency angiographic phenomena based on the plurality of paths and the corresponding intensities associated with respective pixels of the paths, and output for display the spatiotemporal reconstruction of cardiac frequency angiographic phenomena in one or more images.

Abstract: An optical sensor device includes a pixel array and a control circuit. The pixel array has pixel units arranged in N rows and M columns, and a pixel unit comprises: a photo transistor, configured to capture and generate a first image signal during a first shutter exposure time interval of a first time and to capture and generate a second image signal during a second shutter exposure time interval of a second time, the first time and the second time being consecutive; a first integration capacitor, coupled to the photo transistor, for storing the first image signal; and a second integration capacitor, coupled to the photo transistor, for storing the second image signal. The control circuit performs a motion detection to determine whether a motion occurs according to a difference between the two image signals.

Abstract: Described are acoustic absorber materials with high acoustic attenuation and high thermal conductivity comprising an inorganic, porous foam and an absorbing material within at least a portion of the pores of the foam, ultrasound transducers and devices including the same, as well as methods of making the materials.

Abstract: An electronic device, comprising: a first light source, configured to emit first light; a second light source, configured to emit second light; a first optical sensor, configured to sense first optical data generated based on reflected light of the first light; a light guiding device, configured to receive the second light; and a second optical sensor, configured to sense second optical data generated based on the second light emitted by the light guiding device. The first optical sensor and the second optical sensor can be integrated to a single optical sensor.

Abstract: An air ejection device, configured to eject air; a distance detecting circuit, configured to detect distances between an electronic device comprising the object determining system and at least one location of an object when the air ejection device ejects air to the object; and a determining circuit, configured to determine whether the object is a rigidity type object or a soft type object according to the variations.