Patents Assigned to Imperial Innovations Limited
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Patent number: 9995774Abstract: Determining a property of an electrical signal at a node instant at the current instant (INSTC); determining a previous function indicative of a property of the signal at the node at a previous instant; determining an error function in a previous frequency estimation at the node at a previous instant; determining a first current function indicative of the property of the signal at the node at INSTC in accordance with the determined property, the previous function, and the error function; receiving, from another node, a second current function indicative of a property of an electrical signal at the at least one other node at INSTC; combining the first current function and the second current function to produce a current combined function (CCF) indicative of a property of the signal at the node at INSTC; and estimating a current frequency of the signal at the node in accordance with the CCF.Type: GrantFiled: October 3, 2013Date of Patent: June 12, 2018Assignee: IMPERIAL INNOVATIONS LIMITEDInventors: Danilo Mandic, Yili Xia, Dahir Dini
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Patent number: 9994675Abstract: The present invention provides a novel catalyst of formula (I): wherein M is selected from Zn(H), Co(II), Mn(II), Mg(II), Fe(II), Cr(III)-X or Fe(III)-X, and the use thereof in polymerizing carbon dioxide and an epoxide.Type: GrantFiled: October 28, 2014Date of Patent: June 12, 2018Assignee: Imperial Innovations LimitedInventors: Charlotte K. Williams, Michael Kember, Paul Knight
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Publication number: 20180143145Abstract: A sensor comprises a first resonator operable at microwave and/or millimetre wave frequencies and having a first value of quality factor which is equal to or greater than moo at a frequency in a range 1 to 100 GHz and a second resonator having a second value of quality factor which is less than the first value of quality factor and which is positioned and orientated with respect to the first resonator so as to be inductively coupled to the first resonator, the second resonator comprising first and second electrically-conductive regions separated by a gap which provides a sensing region.Type: ApplicationFiled: November 23, 2016Publication date: May 24, 2018Applicant: Imperial Innovations LimitedInventors: Norbert Klein, Clare Watts, Stephen Hanham
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Patent number: 9950355Abstract: Method of forming a component of complex shape from an Al-alloy sheet or a Mg-alloy sheet. The method includes the steps of: a) heating the sheet to a temperature below the solution heat treatment (SHT) temperature for the alloy; b) forming the heated sheet between heated dies into or towards the complex shape; c) heating the sheet to at least its SHT temperature and substantially maintaining that temperature until SHT has been completed; and d) quenching the solution heat treated sheet between cold dies and at the same time completing the forming into the complex shape or maintaining that shape.Type: GrantFiled: November 15, 2010Date of Patent: April 24, 2018Assignee: Imperial Innovations LimitedInventors: Jianguo Lin, Daniel Balint, Lilang Wang, Trevor Anthony Dean, Alistair David Foster
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Patent number: 9954243Abstract: A fuel cell comprising at least two stacked fuel cell boards (22) which each comprise a membrane of substantially gas impervious electrolyte material and at least two electrode pairs wherein the anode and cathode of each said electrode pair are arranged on respective faces of said membrane. An electrode of each pair of electrodes is connected to an electrode of an adjacent pair of electrodes by a through-membrane connection (13) or by an external connection on a Printed Circuit Board, comprising an electrically conductive region of said electrolyte material. A method for forming the through-membrane electrical connections in the electrolyte membrane is also disclosed.Type: GrantFiled: February 29, 2012Date of Patent: April 24, 2018Assignees: Imperial Innovations Limited, UCL Business PLCInventors: Daniel John Leslie Brett, Anthony Robert John Kucernak
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Patent number: 9943840Abstract: This invention relates to a process for the preparation of surface-functionalised metal oxide, metal sulphide, metal selenide or metal telluride nanoparticles, a process for the preparation of a composite material comprising such nanoparticles, nanoparticles and a composite material produced thereby, the use of such nanoparticles in catalysis and a catalyst comprising such nanoparticles.Type: GrantFiled: May 3, 2013Date of Patent: April 17, 2018Assignee: IMPERIAL INNOVATIONS LIMITEDInventors: Milo Shaffer, Charlotte Williams, Katherine Orchard, Neil John Brown, Jonathan Weiner
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Patent number: 9944687Abstract: Peptide containing sequence from both the GLP-1 peptide and glucagon peptide, compositions comprising said peptides and methods of using said peptides for the treatment and prevention of metabolic disorders, for example disorders of energy metabolism such as obesity or diabetes, are provided.Type: GrantFiled: July 4, 2011Date of Patent: April 17, 2018Assignee: Imperial Innovations LimitedInventor: Stephen Robert Bloom
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Patent number: 9932344Abstract: Certain pyrazolo[1,5-a]pyrimidine-5,7-diamine compounds that inhibit cycline dependent kinase (CDK) (e.g., CDK1, CDK2, CDK4, CDK5, CDK6, CDK7, CDK8, CDK9, CDK10, CDK11, CDK12, CDK13, etc.) are disclosed. Pharmaceutical compositions comprising these compounds, and the use of these compounds and compositions to inhibit CDK; to treat disorders associated with CDK such as those arising from an inappropriate activity, mutation, overexpression, or upstream pathway activation of CDK; or disorders that are ameliorated by the inhibition of CDK; proliferative disorders; cancer; viral infections; neurodegenerative disorders; ischaemia; renal diseases; and cardiovascular disorders are also disclosed. Optionally, the treatment further comprises simultaneous or sequential treatment with a further active agent, e.g., an aromatase inhibitor, an anti-estrogen, a Her2 blocker, a cytotoxic chemotherapeutic agent, etc.Type: GrantFiled: February 20, 2015Date of Patent: April 3, 2018Assignees: Cancer Research Technology Limited, Imperial Innovations Limited, Emory UniversityInventors: Alexander Bondke, Sebastian Kroll, Anthony Barrett, Matthew Fuchter, Brian Slafer, Simak Ali, Charles Coombes, James Patrick Snyder
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Patent number: 9934569Abstract: A computer implemented method for tracking a site in a series of images, the method comprising identifying a site to be tracked; selecting at least three non-collinear locations distributed around the sire in the reference image; selecting, from the reference image, a region of image data around each of the at least three non collinear locations; comparing each selected region with a second image and, based on these comparisons, identifying for each selected region a corresponding location in the second image, determining a single common affine transformation to map the at least three locations from the reference image onto the corresponding locations in the second image.Type: GrantFiled: September 4, 2014Date of Patent: April 3, 2018Assignee: Imperial Innovations LimitedInventors: Menglong Ye, Stamatia Giannarou, Guang-Zhong Yang
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Patent number: 9932317Abstract: This invention relates to quinazoline compounds of Formula (I) which are inhibitors of the histone lysine methyltransferase (HKMTase) EZH2, and to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of EZH2 provides a therapeutic or prophylactic effect.Type: GrantFiled: March 19, 2013Date of Patent: April 3, 2018Assignees: Imperial Innovations Limited, Emory UniversityInventors: Robert Brown, Matthew John Fuchter, Nadine Chapman-Rothe, Nitipol Srimongkolpithak, Joachim Caron, James Snyder, Thota Ganesh, Jin Liu, Aiming Sun
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Patent number: 9902903Abstract: The present invention relates to compositions capable of emitting circularly polarized electroluminescence comprising an electroluminescent polymer and a chiral dopant, processes for the synthesis of such compositions and light emitting devices incorporating such compositions.Type: GrantFiled: July 26, 2013Date of Patent: February 27, 2018Assignee: IMPERIAL INNOVATIONS LIMITEDInventors: Matthew Fuchter, Alasdair Campbell, Ying Yang
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Patent number: 9893653Abstract: A device able to generate electrical power through relative rotational motion of first (370, 380) and second (200, 230) principal components around an axis of rotation (220); wherein: the first and second principal components comprise an arrangement of piezoelectric elements (380) and permanent magnets (230, 370) such that the interaction between these magnets and piezoelectric elements, in use, makes it possible to generate electricity; and wherein: the second principal component (200, 230) comprises a center of mass offset from the axis of relative rotation (220) such that the response of the second principal component (200, 230) to either gravitational or inertial forces is a relative rotation of the second principal component (200, 230) in relation to the first principal component (370, 380); the first principal component (370, 380) being fixedly attached to the moving host structure (100).Type: GrantFiled: May 3, 2013Date of Patent: February 13, 2018Assignee: Imperial Innovations LimitedInventors: Eric Morgan Yeatman, Andrew Sean Holmes, Pit Pillatsch
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Publication number: 20180015211Abstract: A blood filter device having an iron-chelating molecule, a haem-binding molecule and a haemoglobin-binding molecule bound to a support. Use of the device in a vessel containing blood, for example a blood bag or a flow line, removes haemolysis-derived components from the blood.Type: ApplicationFiled: December 2, 2015Publication date: January 18, 2018Applicants: IMPERIAL INNOVATIONS LIMITED, UCL BUSINESS PLCInventors: Alan Christopher Spivey, Gregory John Quinlan, Nathan Davies
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Patent number: 9845770Abstract: An asymmetric double-entry turbine is provided with a turbine housing that includes a first volute, a second volute and a turbine receiving bore. The first volute has a first exhaust gas inlet and a first exhaust gas outlet. The second volute has a second exhaust gas inlet and a second exhaust gas outlet. The turbine receiving bore is in fluid communication with the first exhaust gas outlet and the second exhaust gas outlet for conducting a flow of exhaust gas from the first exhaust gas outlet and the second exhaust gas outlet out in an axial direction. The first exhaust gas outlet has an angular opening amount of more than 180 degrees around the turbine receiving bore. The second exhaust gas outlet has an angular opening amount of less than 180 degrees around the turbine receiving bore.Type: GrantFiled: March 14, 2014Date of Patent: December 19, 2017Assignee: Imperial Innovations LimitedInventors: Ricardo Martinez-Botas, Masakazu Sakai
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Patent number: 9843064Abstract: The present invention provides a regenerative fuel cell comprising an anionic membrane capable of selectively passing anions, wherein the pH of the anolyte and/or catholyte is at least 10. The present invention also relates to a method of operating a regenerative fuel cell comprising an anionic membrane capable of selectively passing anions, wherein the pH of the anolyte and/or catholyte is at least 10.Type: GrantFiled: September 19, 2011Date of Patent: December 12, 2017Assignee: IMPERIAL INNOVATIONS LIMITEDInventors: Nigel Brandon, Anthony Kucernak, Vladimir Yufit
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Publication number: 20170348440Abstract: The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium (III) 2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N?-amido-methyl]-1,4,7,10-tetra-azacyclododec-1-yl}-acetic acid), characterised in that said liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phospocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.Type: ApplicationFiled: March 20, 2017Publication date: December 7, 2017Applicants: Medical Research Council, Imperial Innovations LimitedInventors: Nazila KAMALY, Tammy Louise KALBER, Gavin David KENNY, Maya THANOU, Andrew David MILLER, Jimmy BELL
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Publication number: 20170340684Abstract: The invention provides a recombinant targeted bacteriophage for expressing a transgene in a target cell transduced with the bacteriophage. The bacteriophage comprises a first nucleic acid sequence encoding a pill capsid minor coat protein that is configured to display a cell-targeting ligand for enabling delivery of the bacteriophage to a target cell, a second nucleic acid sequence encoding at least one pVIII capsid major coat protein that is configured to display a foreign peptide thereon, and a transgene which encodes a protein which exerts a biological effect on the target cell.Type: ApplicationFiled: May 12, 2014Publication date: November 30, 2017Applicant: IMPERIAL INNOVATIONS LIMITEDInventors: Amin Hajitou, Teerapong Yata
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Publication number: 20170329065Abstract: There is provided a light source arranged to output light at a first wavelength. The light source comprises a luminescent concentrator having a slab-shaped geometry. The luminescent concentrator comprises: an input port arranged to receive light and define a first area; an output port arranged to transmit light and define a second area which is smaller than the first area; and surfaces arranged to direct light inside the luminescent concentrator to the output port. The luminescent concentrator further comprises lumophores arranged to receive light at a second wavelength and emit light at the first wavelength; and a pump light supply coupled to the input port and arranged to illuminate the input port with light at the second wavelength.Type: ApplicationFiled: October 21, 2015Publication date: November 16, 2017Applicant: Imperial Innovations LimitedInventors: Juna Sathian, Mark Oxborrow
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Publication number: 20170260325Abstract: The invention relates to novel conjugated polymers containing one or more units based on dithieno[3,2-c;2?,3?-e]azepine-4,6-dione that is fused to further aromatic rings, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in, or for the preparation of, organic electronic (OE) devices, especially organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising, or being prepared from, these polymers, polymer blends, mixtures or formulations.Type: ApplicationFiled: August 12, 2015Publication date: September 14, 2017Applicants: Merck Patent GmbH, IMPERIAL INNOVATIONS LIMITEDInventors: Nicolas BLOUIN, William MITCHELL, Martin HEENEY, Jessica SHAW
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Patent number: D812750Type: GrantFiled: October 15, 2014Date of Patent: March 13, 2018Assignee: Imperial Innovations LimitedInventors: Guang-Zhong Yang, Stephen Matthews