Patents Assigned to Imperial Innovations Limited
  • Patent number: 9934569
    Abstract: A computer implemented method for tracking a site in a series of images, the method comprising identifying a site to be tracked; selecting at least three non-collinear locations distributed around the sire in the reference image; selecting, from the reference image, a region of image data around each of the at least three non collinear locations; comparing each selected region with a second image and, based on these comparisons, identifying for each selected region a corresponding location in the second image, determining a single common affine transformation to map the at least three locations from the reference image onto the corresponding locations in the second image.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: April 3, 2018
    Assignee: Imperial Innovations Limited
    Inventors: Menglong Ye, Stamatia Giannarou, Guang-Zhong Yang
  • Patent number: 9902903
    Abstract: The present invention relates to compositions capable of emitting circularly polarized electroluminescence comprising an electroluminescent polymer and a chiral dopant, processes for the synthesis of such compositions and light emitting devices incorporating such compositions.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: February 27, 2018
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Matthew Fuchter, Alasdair Campbell, Ying Yang
  • Patent number: 9893653
    Abstract: A device able to generate electrical power through relative rotational motion of first (370, 380) and second (200, 230) principal components around an axis of rotation (220); wherein: the first and second principal components comprise an arrangement of piezoelectric elements (380) and permanent magnets (230, 370) such that the interaction between these magnets and piezoelectric elements, in use, makes it possible to generate electricity; and wherein: the second principal component (200, 230) comprises a center of mass offset from the axis of relative rotation (220) such that the response of the second principal component (200, 230) to either gravitational or inertial forces is a relative rotation of the second principal component (200, 230) in relation to the first principal component (370, 380); the first principal component (370, 380) being fixedly attached to the moving host structure (100).
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: February 13, 2018
    Assignee: Imperial Innovations Limited
    Inventors: Eric Morgan Yeatman, Andrew Sean Holmes, Pit Pillatsch
  • Publication number: 20180015211
    Abstract: A blood filter device having an iron-chelating molecule, a haem-binding molecule and a haemoglobin-binding molecule bound to a support. Use of the device in a vessel containing blood, for example a blood bag or a flow line, removes haemolysis-derived components from the blood.
    Type: Application
    Filed: December 2, 2015
    Publication date: January 18, 2018
    Applicants: IMPERIAL INNOVATIONS LIMITED, UCL BUSINESS PLC
    Inventors: Alan Christopher Spivey, Gregory John Quinlan, Nathan Davies
  • Patent number: 9845770
    Abstract: An asymmetric double-entry turbine is provided with a turbine housing that includes a first volute, a second volute and a turbine receiving bore. The first volute has a first exhaust gas inlet and a first exhaust gas outlet. The second volute has a second exhaust gas inlet and a second exhaust gas outlet. The turbine receiving bore is in fluid communication with the first exhaust gas outlet and the second exhaust gas outlet for conducting a flow of exhaust gas from the first exhaust gas outlet and the second exhaust gas outlet out in an axial direction. The first exhaust gas outlet has an angular opening amount of more than 180 degrees around the turbine receiving bore. The second exhaust gas outlet has an angular opening amount of less than 180 degrees around the turbine receiving bore.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 19, 2017
    Assignee: Imperial Innovations Limited
    Inventors: Ricardo Martinez-Botas, Masakazu Sakai
  • Patent number: 9843064
    Abstract: The present invention provides a regenerative fuel cell comprising an anionic membrane capable of selectively passing anions, wherein the pH of the anolyte and/or catholyte is at least 10. The present invention also relates to a method of operating a regenerative fuel cell comprising an anionic membrane capable of selectively passing anions, wherein the pH of the anolyte and/or catholyte is at least 10.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: December 12, 2017
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Nigel Brandon, Anthony Kucernak, Vladimir Yufit
  • Publication number: 20170348440
    Abstract: The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium (III) 2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N?-amido-methyl]-1,4,7,10-tetra-azacyclododec-1-yl}-acetic acid), characterised in that said liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phospocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.
    Type: Application
    Filed: March 20, 2017
    Publication date: December 7, 2017
    Applicants: Medical Research Council, Imperial Innovations Limited
    Inventors: Nazila KAMALY, Tammy Louise KALBER, Gavin David KENNY, Maya THANOU, Andrew David MILLER, Jimmy BELL
  • Publication number: 20170340684
    Abstract: The invention provides a recombinant targeted bacteriophage for expressing a transgene in a target cell transduced with the bacteriophage. The bacteriophage comprises a first nucleic acid sequence encoding a pill capsid minor coat protein that is configured to display a cell-targeting ligand for enabling delivery of the bacteriophage to a target cell, a second nucleic acid sequence encoding at least one pVIII capsid major coat protein that is configured to display a foreign peptide thereon, and a transgene which encodes a protein which exerts a biological effect on the target cell.
    Type: Application
    Filed: May 12, 2014
    Publication date: November 30, 2017
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Amin Hajitou, Teerapong Yata
  • Publication number: 20170329065
    Abstract: There is provided a light source arranged to output light at a first wavelength. The light source comprises a luminescent concentrator having a slab-shaped geometry. The luminescent concentrator comprises: an input port arranged to receive light and define a first area; an output port arranged to transmit light and define a second area which is smaller than the first area; and surfaces arranged to direct light inside the luminescent concentrator to the output port. The luminescent concentrator further comprises lumophores arranged to receive light at a second wavelength and emit light at the first wavelength; and a pump light supply coupled to the input port and arranged to illuminate the input port with light at the second wavelength.
    Type: Application
    Filed: October 21, 2015
    Publication date: November 16, 2017
    Applicant: Imperial Innovations Limited
    Inventors: Juna Sathian, Mark Oxborrow
  • Publication number: 20170260325
    Abstract: The invention relates to novel conjugated polymers containing one or more units based on dithieno[3,2-c;2?,3?-e]azepine-4,6-dione that is fused to further aromatic rings, to methods for their preparation and educts or intermediates used therein, to polymer blends, mixtures and formulations containing them, to the use of the polymers, polymer blends, mixtures and formulations as organic semiconductors in, or for the preparation of, organic electronic (OE) devices, especially organic photovoltaic (OPV) devices and organic photodetectors (OPD), and to OE, OPV and OPD devices comprising, or being prepared from, these polymers, polymer blends, mixtures or formulations.
    Type: Application
    Filed: August 12, 2015
    Publication date: September 14, 2017
    Applicants: Merck Patent GmbH, IMPERIAL INNOVATIONS LIMITED
    Inventors: Nicolas BLOUIN, William MITCHELL, Martin HEENEY, Jessica SHAW
  • Publication number: 20170247508
    Abstract: The present invention provides a novel catalyst of formula (I): wherein M is selected from Zn(H), Co(II), Mn(II), Mg(II), Fe(II), Cr(III)—X or Fe(III)—X, and the use thereof in polymerising carbon dioxide and an epoxide.
    Type: Application
    Filed: April 7, 2017
    Publication date: August 31, 2017
    Applicant: Imperial Innovations Limited
    Inventors: Charlotte Katherine Williams, Michael Kember, Paul Knight
  • Patent number: 9732141
    Abstract: A T cell receptor molecule (TCR) containing an alpha chain portion and a beta chain portion wherein the alpha chain portion contains three complementarity determining regions (CDRs): CDR1?: SSYSPS CDR2?: YTSAATL CDR3?: VVSPFSGGGADGLT or comprising or consisting of SPPSGGGADGLT and the beta chain portion contains three complementarity determining regions (CDRs): CDR1?: DFQATT CDR2?: SNEGSKA CDR3?: comprising SARDGGEG or comprising or consisting of RDGGEGSETQY, or wherein up to three amino acid residues in one or more CDRs are replaced by another amino acid residue. The invention also includes polynucleotides encoding the TCR molecules, and host cells containing the said polynucleotides. Patient derived T cells may have the polynucleotides encoding the TCR molecules introduced therein, and the engineered T cells may be introduced into the patient in order to combat a WT1-expressing malignancy.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: August 15, 2017
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Hans Josef Stauss, Liquan Gao, Shao-An Xue
  • Patent number: 9709598
    Abstract: A method for interrogating a surface using scanning ion conductance microscopy (SICM), comprising the steps of: a) repeatedly bringing a SICM probe into proximity with the surface at discrete, spaced locations in a region of the surface and measuring surface height at each location; b) estimating surface roughness or other characteristic for the region based upon the surface height measurements; and c) repeatedly bringing the probe into proximity with the surface at discrete, spaced locations in the region, the number and location of which is based upon the estimated surface roughness or other characteristic in the region, and obtaining an image of the region with a resolution adapted to the surface roughness or other characteristic.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: July 18, 2017
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Pavel Novak, Chao Li, Andrew Shevchuk, Victor Petrovich Ostanin, David Klenerman, Yuri Evgenievich Korchev, Gregory Frolenkov, Richard Clarke
  • Patent number: 9708913
    Abstract: A turbine wheel for low-pressure ratio applications is disclosed. The ratio of the outlet area of the wheel (A2) to the inlet area of the wheel (A1) is less than approximately 0.4. In an embodiment, the wheel is a radial or mixed-flow wheel.
    Type: Grant
    Filed: February 2, 2012
    Date of Patent: July 18, 2017
    Assignee: Imperial Innovations Limited
    Inventors: Ricardo Fernando Martinez-Botas Mateo, Alessandro Romagnoli, Aman Mohd Ihsan Bin Mamat
  • Patent number: 9677856
    Abstract: A method of constructing a concealing volume comprises constructing a plurality of concealing volume elements around a concealable volume. Each concealing volume element has a material parameter arranged to direct a propagating wave around the concealable volume. The material parameter can be refractive index, electrical permittivity and magnetic permittivity. The concealing volume can be a metamaterial. The concealing volume diverts incoming propagating waves such that outgoing propagating waves appear to be unperturbed to an observer.
    Type: Grant
    Filed: July 25, 2006
    Date of Patent: June 13, 2017
    Assignees: Imperial Innovations Limited, Duke University
    Inventors: John Pendry, David Smith, David Schurig
  • Publication number: 20170144938
    Abstract: The present invention relates to a method of making a monolith having a plurality of channels extending therethrough, the method comprising, providing a suspension of polymer-coated particles in a first solvent; extruding the suspension from a primary orifice, while passing one or more second solvents from a plurality of secondary orifices arranged within the first orifice, into a third solvent, whereby a monolith precursor is formed from the polymer and particles, and sintering the monolith precursor to form a monolith.
    Type: Application
    Filed: May 14, 2015
    Publication date: May 25, 2017
    Applicant: Imperial Innovations Limited
    Inventors: Kang Li, Zhentao Wu
  • Patent number: 9656020
    Abstract: According to a first aspect of the present invention there is provided a controller for controlling a glucagon pump. The controller comprises an input 8 for receiving an input signal indicative of a measured blood glucose concentration, an output 9 for providing a pulsed glucagon pump drive signal, each pulse being arranged to cause a glucagon pump to deliver a volume of glucagon, and a processing unit 10 for setting the pulse frequency of the pump drive signal in dependence upon the input signal, such that when the input signal indicates that the measured blood glucose concentration is above a threshold concentration the pulse frequency is zero and when the input signal indicates that the measured blood glucose concentration is below the threshold concentration the pulse frequency is increased as the measured blood glucose concentration decreases.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: May 23, 2017
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Pantelis Georgiou, Kok Thay Lim, Christofer Toumazou
  • Patent number: 9642875
    Abstract: The invention provides a propionate inulin ester for the reduction of appetite, food intake and/or calorie intake and/or to improve insulin sensitivity in a subject, and for the treatment or prevention of obesity or diabetes. The invention also provides compositions comprising a propionate inulin ester, methods using propionate inulin esters, functional food containing propionate inulin ester and methods of making propionate inulin esters.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: May 9, 2017
    Assignees: The University Court of the University of Glasgow, Imperial Innovations Limited
    Inventors: Gary Frost, Douglas Morrison, Thomas Preston
  • Publication number: 20170121129
    Abstract: A robotic control device for receiving manipulation instructions for an end effector of a surgical instrument has a platform for supporting a haptic manipulator device, the platform being movably coupled to a surface for supporting the platform and having a movement facilitating member operable to change the amount of force required to move the platform relative to the surface.
    Type: Application
    Filed: December 13, 2011
    Publication date: May 4, 2017
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: George MYLONAS, Guang-Zhong YANG
  • Patent number: D812750
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: March 13, 2018
    Assignee: Imperial Innovations Limited
    Inventors: Guang-Zhong Yang, Stephen Matthews