Patents Assigned to Imperial Innovations Limited
  • Vehicle comprising at least one apparatus for reducing drag on the vehicle
    Patent number: 9487250
    Abstract: A vehicle comprising at least one pressure-drag-reducing apparatus (1) for reducing the pressure drag on the vehicle. The apparatus comprises: a housing (31) at least partly defining a cavity (34) and an aperture (35) in the housing (31), the cavity (34) in fluid communication via the aperture (35) with the environment surrounding the vehicle; and oscillating means (32, 36) for creating an oscillation in pressure across the aperture between the cavity and the environment. The cavity volume, the frequency of oscillation, the aperture size and the amplitude of oscillation are arranged to cause fluid to be alternately drawn into, and ejected from, the cavity through the aperture. The apparatus is positioned relative to the remainder of the vehicle such that the ejected fluid entrains fluid from the environment to reduce pressure drag on the vehicle.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: November 8, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Jonathan Finlay Morrison, Anthony Oxlade, Ala Makram Qubain, Juan Marcos Garcia de la Cruz Lopez
  • Glycodendrimers of polypropyletherimine
    Patent number: 9453040
    Abstract: A glycodendrimer comprising: a) a non-toxic dendrimer polypropyletherimine core supporting on average in the range of 9 to 64 terminal carboxylic acid groups, and b) conjugated to said core in the range of 2 to 8 amino sugars or a sulphate amino sugar selected from the group consisting of glucosamine, N-acetyl glucosamine, mannosamine, N-acetylmannosamine, galactosamine, a sulphate of any one of the same and a combination thereof, wherein each sugar is linked directly through a zero length amide bond with a residue of a terminal carboxylic acid group. The invention also extends to defined populations comprising said glycodendrimer molecules, pharmaceutical compositions comprising said molecules or populations, process for preparing the molecules and formulations, and therapeutic uses of the molecules, populations and compositions.
    Type: Grant
    Filed: August 22, 2011
    Date of Patent: September 27, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Sunil Shaunak, Ian Alfred Teo
  • Bimetallic catalytic complexes for the copolymerization of carbon dioxide and an epoxide
    Patent number: 9453104
    Abstract: The present invention provides a novel catalyst of formula (I): wherein M is selected from Zn(H), Co(II), Mn(II), Mg(II), Fe(II), Cr(III)-X or Fe(III)-X, and the use thereof in polymerizing carbon dioxide and an epoxide.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: September 27, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Charlotte K. Williams, Michael Kember, Paul Knight
  • Ceramic material
    Patent number: 9434650
    Abstract: The present invention relates to method for forming a porous ceramic material, the method comprising the steps of: providing a suspension of polymer-coated ceramic particles in a first solvent; contacting the suspension with a second solvent, whereby a ceramic material precursor is formed from the polymer and ceramic particles, heating the ceramic material precursor to at least partially decompose the polymer within the precursor into solid deposits, and then sintering the ceramic material precursor to form a porous ceramic material.
    Type: Grant
    Filed: October 9, 2013
    Date of Patent: September 6, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Benjamin Francis Knatchbull Kingsbury, Zhentao Wu, Kang Li
  • METHOD AND APPARATUS FOR TRANSMITTING SIGNALS VIA MISO BROADCAST CHANNEL WITH IMPERFECT CSIT
    Publication number: 20160249369
    Abstract: A system and method for transmitting signals via multi-input single-output (MISO) broadcast channel with imperfect channel state information at the transmitter (CSIT). The transmitter receives each CSI of from the plural receivers, determines a transmit power and a transmission rate based on the CSI qualities of the plural receivers calculated from the each CSI, and transmits the signal using the transmit power and the transmission rate. The signal comprises a user specific message, a first common message and a second common message to compensate imperfect CSIT.
    Type: Application
    Filed: October 7, 2014
    Publication date: August 25, 2016
    Applicants: SAMSUNG ELECTRONICS CO., LTD., IMPERIAL INNOVATIONS LIMITED
    Inventors: Seunghoon Choi, Chenxi Hao, Bruno Clerckx
  • Apparatus and method for programming a pacemaker
    Patent number: 9399138
    Abstract: A pacemaker programming apparatus for programming a pacemaker in an individual. The apparatus comprises means for determining the sensed-paced difference of the pacemaker in the individual: first testing means for determining the optimum AV delay while the pacemaker is atrially pacing at a raised at a heart rate; and calculation means for calculating the optimum AV delay determined by the first testing means minus the sensed-paced difference.
    Type: Grant
    Filed: April 20, 2007
    Date of Patent: July 26, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Zachary Whinnett, Darrel Francis
  • Steerable probes
    Patent number: 9398841
    Abstract: A steerable probe comprises a body and drive means arranged to drive the probe through a sample. The body comprises at least three body sections extending parallel to each other along the probe and each movable relative to the others along the probe. The drive means is arranged to move each of the body sections in turn relative to the others thereby to drive the probe through the sample.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: July 26, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Ferdinando Marie Rodriguez Y Baena, Luca Frasson
  • Medical master/slave type device for minimally invasive surgery
    Patent number: 9387043
    Abstract: Apparatus for Minimal Invasive Surgery (MIS) comprising a master device, a slave device, a detector for detecting a parameter of, or associated with the slave device, and a shape locking system for locking the shape of the master device in response to a parameter detected by the detector.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: July 12, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Guang-Zhong Yang, George Mylonas, Christopher Payne
  • Regenerative fuel cells
    Patent number: 9391339
    Abstract: The present invention provides a regenerative fuel cell comprising a reversible hydrogen gas anode, in an anode compartment and a reversible cathode in a cathode compartment, wherein the redox reaction at the cathode is selected from formula (i), formula (ii) and formula (iii).
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: July 12, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Nigel Brandon, Vladimir Yufit
  • Passively controlled turbocharger
    Patent number: 9388707
    Abstract: A flow control device for a turbocharger, the flow control device comprising a variably restricting flow restrictor for restricting flow in a turbocharger inlet by a variable amount, the flow control device being arranged such that the flow restrictor position varies flow restriction in response to force acting on a surface of the flow restrictor caused by a pressure pulse in a flow direction, the flow restrictor being biased in a direction opposed to the flow direction.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: July 12, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Ricardo Martinez-Botas, Srithar Rajoo, Apostolos Pesiridis, Harminder Flora
  • Anticoagulant fusion protein anchored to cell membrane
    Patent number: 9376684
    Abstract: The invention relates to the inhibition of blood coagulation, especially during organ rejection, and in particular the inhibition of delayed vascular rejection. The invention provides anticoagulant proteins which are anchored to cell membranes. The anticoagulant function is preferably provided by heparin, antithrombin, hirudin, TFPI, tick anticoagulant peptide, or a snake venom factor. These anticoagulant proteins are preferably prevented from being constitutively expressed at the cell surface. In particular, expression at the cell surface is regulated according to cell activation, for instance by targeting the protein to a suitable secretory granule. Expression of these proteins renders cells, tissues and organs less vulnerable to rejection after transplantation (e.g. after xenotransplantation).
    Type: Grant
    Filed: March 17, 2011
    Date of Patent: June 28, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Kristian Riesbeck, Anthony Dorling, Andrew John Timothy George, Robert Ian Lechler
  • Scanning ion conductance microscopy using piezo actuators of different response times
    Patent number: 9354249
    Abstract: A method for interrogating a surface using scanning ion conductance microscopy (SICM), comprising the steps of: a) repeatedly bringing a SICM probe into proximity with the surface at discrete, spaced locations in a region of the surface and measuring surface height at each location; b) estimating surface roughness or other characteristic for the region based upon the surface height measurements; and c) repeatedly bringing the probe into proximity with the surface at discrete, spaced locations in the region, the number and location of which is based upon the estimated surface roughness or other characteristic in the region, and obtaining an image of the region with a resolution adapted to the surface roughness or other characteristic.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: May 31, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Pavel Novak, Chao Li, Andrew Shevchuk, Victor Petrovich Ostanin, David Klenerman, Yuri Evgenievich Korchev, Gregory Frolenkov, Richard Clarke
  • Peptide secreted by with immunomodulating function
    Patent number: 9340588
    Abstract: Among the fewer than 10 proteins primarily secreted by the species Lactobacillus plantarum, there is one of 30 kDa that contains an internal fragment without cleavage sites for the most important intestinal proteases and characterized by having a serine and threonine content of at least 50%. The genetic information encoded in this fragment, designated ST peptide, has been used for producing and purifying the peptide, thus making it possible to conduct various tests in vitro. To summarize, the ST peptide is considered to promote the process of immunologic ignorance of our gastrointestinal immune system toward the commensal bacteria of our gastrointestinal tract, thus favoring the mechanisms of oral tolerance. Therefore the ST peptide could be used in immunotherapy, especially in the context of certain autoimmune diseases and certain inflammatory diseases.
    Type: Grant
    Filed: September 7, 2012
    Date of Patent: May 17, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Borja Sanchez Garcia, Abelardo Margolles Barros, David Bernardo Ordiz, Stella C. Knight, Hafid Omar
  • Methods for diagnosing rheumatoid arthritis
    Patent number: 9334487
    Abstract: The present invention relates to methods of diagnosing, prognosing, preventing or delaying onset of or treating rheumatoid arthritis, methods of distinguishing between different types or stages of rheumatoid arthritis, of identifying an individual at risk of developing rheumatoid arthritis, and of monitoring efficacy of a treatment regime in an individual being treated for rheumatoid arthritis, using a citrullinated enolase peptide to detect or capture antibodies associated with rheumatoid arthritis.
    Type: Grant
    Filed: October 22, 2012
    Date of Patent: May 10, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Karin Lundberg, Patrick Venables, Andrew Kinloch
  • BACTERIOPHAGE-POLYMER HYBRID
    Publication number: 20160114032
    Abstract: The invention provides a targeted bacteriophage-polymer complex comprising a recombinant targeted-bacteriophage and a cationic polymer. The complex has a net positive charge. The invention provides methods of preparing bacteriophages and complexes thereof, and to their uses for the delivery of transgenes in a variety of gene therapy applications.
    Type: Application
    Filed: May 12, 2014
    Publication date: April 28, 2016
    Applicant: Imperial Innovations Limited
    Inventors: Amin Hajitou, Teerapong Yata
  • METHOD AND CATALYST SYSTEM FOR PREPARING POLYMERS AND BLOCK COPOLYMERS
    Publication number: 20160108181
    Abstract: The present invention provides methods for producing block copolymers, either by the sequential addition of monomers, or using a “one-pot” method. The invention also relates to novel methods for producing polyesters by ring opening lactides and/or lactones and by copolymerising anhydrides and epoxides.
    Type: Application
    Filed: May 16, 2014
    Publication date: April 21, 2016
    Applicant: Imperial Innovations Limited
    Inventors: Charlotte Katherine Williams, Charles Romain, Michael Kember
  • Method for treatment of post operative cognitive dysfunction
    Patent number: 9308254
    Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: April 12, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Mervyn Maze, Marc Feldman, Niccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman
  • INDUCTION OF CROSS-REACTIVE CELLULAR RESPONSE AGAINST RHINOVIRUS ANTIGENS
    Publication number: 20160095916
    Abstract: The present invention concerns: a) an isolated peptide comprising an amino acid sequence which is at least 90% identical to the VP4 amino acid sequence of a rhinovirus, or an isolated polynucleotide comprising a nucleic acid sequence encoding said peptide, placed under the control of the elements necessary for its expression in a mammalian cell; and/or b) an isolated peptide comprising an amino acid sequence of at least 100 amino acids which is at least 90% identical to an amino acid sequence located in the last 363 C-terminal amino acids of the RNA polymerase of a rhinovirus, or an isolated polynucleotide comprising a nucleic acid sequence encoding said peptide, placed under the control of the elements necessary for its expression in a mammalian cell; and c) a Th1 adjuvant when said immunogenic composition comprises one or more of said isolated peptides.
    Type: Application
    Filed: February 6, 2014
    Publication date: April 7, 2016
    Applicants: SANOFI PASTEUR, IMPERIAL INNOVATIONS LIMITED
    Inventors: Gary McLean, Walton Ross, Sebastian Johnson, Nathan Bartlett, Bruno Guy, Yves Girerd-Chambaz, Valerie Lecouturier, Jeffrey Almond, Nicholas Glanville, Nicolas Burdin
  • Device and method for generating stimulated emission of microwave or radio frequency radiation
    Patent number: 9293890
    Abstract: A device for, and a method of, generating stimulated emission of microwave or radio frequency electromagnetic radiation, utilize a resonator structure, an input source of microwave or radio frequency electromagnetic radiation to be amplified, and an input of energy arranged to pump the resonator structure and thereby cause amplification of the electromagnetic radiation. The configuration of the resonator structure and/or the materials used in its construction give rise to an increase in the magnetic Purcell factor of the resonator structure.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: March 22, 2016
    Assignee: Imperial Innovations Limited
    Inventors: Jonathan David Baxendale Breeze, Neil McNeill Alford
  • IMAGE DISPLAY INTERFACES
    Publication number: 20160073913
    Abstract: Apparatus for monitoring activation in a heart comprises a probe (100), a plurality of electrodes (101, 102) supported on the probe and each arranged to detect electrical potential at a respective position in the heart during a series of activations, and processing means (104) arranged to analyse the detected electrical potentials to identify a propagation direction of the activation, and to generate an output indicative of that direction.
    Type: Application
    Filed: April 22, 2014
    Publication date: March 17, 2016
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Darrel Francis, Prapa Kanagaratnam