Patents Assigned to Incept
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Patent number: 11224434Abstract: Disclosed are coating compositions, processes, and designs for endowing vascular devices with thromboresistant and endothelializing properties. Also disclosed are designs of vascular devices used as aneurysm treating devices for assisting in the delivery, packing, and maintenance of embolization coils within an aneurysm, particularly a neurovascular aneurysm.Type: GrantFiled: April 30, 2020Date of Patent: January 18, 2022Assignee: Incept, LLCInventors: Yi Yang, Tiffany C. Suekama, Syed Hossainy, Viet Ton, Farhad Khosravi, Alex Jared Rowson, Benjamin Robert Palone, Henry Lao
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Patent number: 11160883Abstract: Implantable materials visible under ultrasound may be delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.Type: GrantFiled: March 12, 2020Date of Patent: November 2, 2021Assignee: Incept, LLCInventors: Patrick Campbell, Amarpreet S. Sawhney
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Patent number: 11154624Abstract: Implantable materials visible under ultrasound may be delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.Type: GrantFiled: March 12, 2020Date of Patent: October 26, 2021Assignee: Incept, LLCInventors: Patrick Campbell, Amarpreet S. Sawhney
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Patent number: 11147949Abstract: A method of making a high flexibility distal zone on a neurovascular catheter is provided. The method includes the steps of dip coating a removable mandrel to form a tubular inner layer on the mandrel, coating the tubular inner layer with a tie layer, applying a helical coil to the outside of the tie layer, positioning a plurality of tubular segments, heating the tubular segments to form the high flexibility distal zone on the neurovascular catheter; and removing the mandrel.Type: GrantFiled: August 16, 2019Date of Patent: October 19, 2021Assignee: INCEPT, LLCInventors: Yi Yang, Farhad Khosravi, Lisa M. Young
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Patent number: 11123090Abstract: A neurovascular catheter having an angled distal tip has an elongate flexible tubular body with a proximal end, a distal end and a side wall defining a central lumen. The side wall has a helical coil. A tubular jacket surrounds the helical coil, and extending distally beyond the helical coil distal end to terminate in a catheter distal face. A tubular radiopaque marker is embedded in the tubular jacket in between the distal end of the coil and the distal face. The distal face resides on a plane which crosses a longitudinal axis of the tubular body at an angle within the range of from about 35 degrees to about 55 degrees. The marker has a proximal face that is approximately perpendicular to the longitudinal axis and a distal face that resides on a plane which crosses the longitudinal axis at an angle within the range of from about 35 degrees to about 55 degrees.Type: GrantFiled: May 1, 2019Date of Patent: September 21, 2021Assignee: Incept, LLCInventors: Yi Yang, Ashoor Shahbazi Yourgenlow, Lisa M. Young, Brandon Yee
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Patent number: 11083802Abstract: Implantable materials visible under ultrasound may delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.Type: GrantFiled: March 12, 2020Date of Patent: August 10, 2021Assignee: Incept, LLCInventors: Patrick Campbell, Amarpreet S. Sawhney
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Patent number: 10973666Abstract: Flared stents are disclosed, and apparatus and methods for delivering such stents into a bifurcation between a main vessel and a branch vessel. The stent includes a first tubular portion a second flaring portion that may be flared radially outwardly to contact the ostium. The stent may include variable mechanical properties along its length. The stent may be delivered using a catheter including proximal and distal ends, the stent overlying first and second balloons on the distal end. During use, the catheter is advanced through an ostium into the branch to place the stent within the branch. The first balloon is expanded to flare the stent to contact a wall of the ostium, thereby causing the stent to migrate partially into the ostium. The second balloon is expanded to fully expand the stent within the ostium and branch.Type: GrantFiled: October 8, 2018Date of Patent: April 13, 2021Assignee: INCEPT, LLCInventor: Jeffrey A. Krolik
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Patent number: 10940231Abstract: Methods are provided for making freeze dried hydrogel and structures therefrom that may be introduced into a patient's body for medical applications. Precursor components are combined to initiate crosslinking. The combined precursor components are placed in a chilled tray, and allowed to crosslink to a desired level of complete crosslinking before and/or after being placed onto the tray. The partially crosslinked hydrogel is frozen and freeze dried. After freeze drying, the hydrogel is conditioned to substantially complete crosslinking, and formed into one or more structures, e.g., plugs, hemostatic, or other medical devices. For example, the hydrogel may be cut, machined, rolled, folded, compressed, and/or cored into that may be loaded into delivery devices that may be introduced into a body to implant or otherwise deliver the structures into the body, e.g., to seal a puncture or other passage through tissue.Type: GrantFiled: July 9, 2014Date of Patent: March 9, 2021Assignee: Incept, LLCInventors: Amarpreet S. Sawhney, Steven L. Bennett, Suresh S. Pai, Scott R. Sershen, Fred H. Co
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Patent number: 10905765Abstract: Serial-solvent biomaterials are described. Embodiments include materials made in an organic solvent that are stripped of the solvent and used in a patient, where they imbibe water and form a hydrogel. These materials are useful for, among other things, delivering therapeutic agents, tissue augmentation, and radiological marking.Type: GrantFiled: October 29, 2015Date of Patent: February 2, 2021Assignee: Incept, LLCInventors: Peter Jarrett, Rami El-Hayek, Amarpreet S. Sawhney
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Patent number: 10849647Abstract: An apparatus and method are provided for accessing and/or removing material from a body lumen. The apparatus includes a tubular sheath including a shaft having a proximal end and an expandable distal end that is expandable between a collapsed configuration and an expanded, tapered configuration. A treatment member can be introduced into the body lumen through the tubular sheath. The treatment member includes one or more expandable members to interact with the material to be removed from the body lumen.Type: GrantFiled: September 26, 2018Date of Patent: December 1, 2020Assignee: Incept, Inc.Inventors: Jeffrey A. Krolik, James H. Dreher, Gwendolyn A. Watanabe
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Patent number: 10835711Abstract: A telescoping catheter is provided such as for distal neurovascular aspiration or access. The catheter includes an elongate, flexible tubular body, having a proximal section with at least one lumen and a distal section which is axially movably positioned within the lumen. A control is provided for advancing the distal section from a first, proximally retracted position within the proximal section to a second extended position, extending distally beyond the proximal section. The distal end of at least one of the proximal and distal sections may be provided with at least one active feature, such as at least one movable jaw or rotatable agitator, to assist in the capture of vascular obstruction. The jaw may be operable in response to application of pulsatile negative pressure through the catheter.Type: GrantFiled: February 27, 2017Date of Patent: November 17, 2020Assignee: Incept, LLCInventors: Yi Yang, Farhad Khosravi, Joseph Rimsa
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Patent number: 10835272Abstract: A system for removing embolic material from an intravascular site is disclosed. The system includes an elongate, flexible tubular body, having a proximal end, a distal end, and a tubular side wall defining at least one lumen extending axially there through; an axial restraint carried by the side wall and exposed to the lumen; a rotatable core wire extendable through the lumen, the core wire having a distal end; a limit carried by the core wire, the limit having a bearing surface for rotatably engaging the restraint; and an agitator tip on the distal end of the core wire. The limit and the restraint are engageable to permit rotation of the core wire but limit distal advance of the tip relative to the tubular body.Type: GrantFiled: April 30, 2019Date of Patent: November 17, 2020Assignee: Incept, LLCInventors: Yi Yang, Farhad Khosravi, Lex Philip Jansen, Ryan Taylor Krone, Miranda Ray, Carolyn Stone, Tiffany Tran Ngo
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Publication number: 20200323535Abstract: Disclosed are coating compositions, processes, and designs for endowing vascular devices with thromboresistant and endothelializing properties. Also disclosed are designs of vascular devices used as aneurysm treating devices for assisting in the delivery, packing, and maintenance of embolization coils within an aneurysm, particularly a neurovascular aneurysm.Type: ApplicationFiled: April 30, 2020Publication date: October 15, 2020Applicant: Incept, LLCInventors: Yi Yang, Tiffany C. Suekama, Syed Hossainy, Viet Ton, Farhad Khosravi, Alex Jared Rowson, Benjamin Robert Palone, Henry Lao
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Patent number: 10786462Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.Type: GrantFiled: August 6, 2019Date of Patent: September 29, 2020Assignee: Incept, LLCInventors: Peter Jarrett, Michael J. McGrath, Timothy S. Jarrett, Rami El-Hayek, Andrew C. Vanslette, Courtney A. Rosales, Charles D. Blizzard, Amarpreet S. Sawhney
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Patent number: 10786581Abstract: Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.Type: GrantFiled: March 8, 2019Date of Patent: September 29, 2020Assignee: Incept, LLCInventors: Patrick Campbell, Amarpreet S. Sawhney
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Patent number: 10779947Abstract: Methods and devices are disclosed for treating neurovascular venous outflow obstructions, with or without implantation of a prosthetic valve. The valve may be carried by a support, such as a stent, which may be self-expandable or balloon expandable. Both transvascular and direct surgical access is contemplated.Type: GrantFiled: May 8, 2017Date of Patent: September 22, 2020Assignee: Incept, LLCInventors: Fred Khosravi, Gerard von Hoffmann
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Patent number: 10661053Abstract: A method of aspirating a vascular occlusion from a remote site is provided. The method includes the steps of advancing a first elongate tubular body through a vascular access site and into a body vessel, advancing a second tubular body distally to extend beyond the first elongate tubular body to reach the remote site, and aspirating thrombus from the site into the lumen by applying pulsatile vacuum to the first elongate tubular body. The second tubular body has a lumen and a length that is shorter than the first elongate tubular body. The pulsatile application of vacuum may cause the distal tip of the second tubular body to open and close like a jaw, which facilitates reshaping the thrombus or biting or nibbling the thrombus material into strands or pieces to facilitate proximal withdrawal under negative pressure through the lumen of the second tubular body.Type: GrantFiled: February 27, 2017Date of Patent: May 26, 2020Assignee: Incept, LLCInventors: Yi Yang, Farhad Khosravi, Joseph Rimsa
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Patent number: 10653426Abstract: Disclosed are coating compositions, processes, and designs for endowing vascular devices with thromboresistant and endothelializing properties. Also disclosed are designs of vascular devices used as aneurysm treating devices for assisting in the delivery, packing, and maintenance of embolization coils within an aneurysm, particularly a neurovascular aneurysm.Type: GrantFiled: January 4, 2018Date of Patent: May 19, 2020Assignee: Incept, LLCInventors: Yi Yang, Tiffany C. Suekama, Syed Hossainy, Viet Ton, Farhad Khosravi, Alex Jared Rowson, Benjamin Robert Palone, Henry Lao
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Patent number: 10617563Abstract: A prosthesis comprising a water-dissolvable coating. A prosthesis for a lacrimal canaliculus comprising a swellable punctal plug with a proximal end and a distal end, with the plug comprising a water-dissolvable biocompatible coating on the distal and/or the proximal end. Materials and methods for making and using the same. A prosthesis for placement in or across natural or prosthetic lumens, ostia, ducts, sinus, or sphincters, the prosthesis comprising a coating. The prosthesis can further provide a depot for sustained drug delivery to tissue.Type: GrantFiled: July 22, 2016Date of Patent: April 14, 2020Assignee: Incept, LLCInventors: Peter Jarrett, Amarpreet S. Sawhney, Michael J. McGrath, Arthur Driscoll, Ankita D. Desai, Michael Bassett
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Patent number: 10550187Abstract: Methods and devices for treating a luminal pathology affecting an anatomical lumen of a patient comprising forming, in situ, a continuous cohesive layer of covalently-crosslinked hydrogel in a luminal wall of the anatomical lumen.Type: GrantFiled: October 23, 2015Date of Patent: February 4, 2020Assignee: Incept, LLCInventors: Amarpreet S. Sawhney, Farhad Khosravi, Patrick Campbell