Patents Assigned to Institute of Technology
  • Decoupling of parallel transmission arrays in magnetic resonance imaging
    Patent number: 10295624
    Abstract: A method of determining a decoupling matrix of a decoupling system for an array of coils of a parallel transmission magnetic resonance imaging (MRI) system includes obtaining impedance matrix data for the array of coils without the decoupling system, determining, based on the impedance matrix data for the array of coils, an objective function representative of deviation from a decoupled operating condition for the array of coils in which the array of coils are decoupled via the decoupling system, and defining, with a processor, a decoupling matrix representative of a set of impedances of the decoupling system with an iterative procedure that optimizes elements of the decoupling matrix to minimize the objective function and reach the decoupled operating condition.
    Type: Grant
    Filed: June 14, 2013
    Date of Patent: May 21, 2019
    Assignees: Massachusetts Institute of Technology, Massachusetts General Hospital, Siemens Healthcare GmbH
    Inventors: Elfar Adalsteinsson, Luca Daniel, Bastien Guerin, Zohaib Mahmood, Markus Vester, Lawrence Wald
  • Zinc ferrite film and method for manufacturing zinc ferrite film
    Patent number: 10294119
    Abstract: A method for manufacturing a zinc ferrite film includes forming a zinc ferrite film on a base material by having a reaction liquid, which contains metal ions including only bivalent iron ions and bivalent zinc ions, contact an oxidation liquid, which contains an oxidant that oxidizes the metal ions, in the presence of a pH adjuster. The pH adjuster includes a carbonate of ammonium and an alkali metal salt of mono-carboxylic acid.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: May 21, 2019
    Assignees: Shinko Electric Industries Co., LTD., Tokyo Institute of Technology
    Inventors: Nobuhiro Matsushita, Yuji Tanaka, Tomoki Kobayashi
  • Modified alginates for cell encapsulation and cell therapy
    Patent number: 10292936
    Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for the encapsulation and transplantation of cells. Also disclosed are high throughput methods for the characterizing the biocompatibility and physiochemical properties of modified alginate polymers.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: May 21, 2019
    Assignees: Massachusetts Institute of Technology, The Children's Medical Center Corporation
    Inventors: Arturo J. Vegas, Minglin Ma, Kaitlin M Bratlie, Daniel G. Anderson, Robert S. Langer
  • Data editing device and data editing method
    Patent number: 10296496
    Abstract: A data storage unit of a data editing apparatus stores both a base indicating a data attribute and a data value in association with each other as data to be edited. A code acquisition unit acquires a user code, which is a code described in a first program language for describing data editing details by intensive notation and which describes editing details for the data to be edited that are based on the base. A code generation unit generates, in accordance with a predetermined correspondence relationship between a second program language for describing data editing details by extensive notation and the first program language, an execution code described in the second program language based on the user code. An editing processing unit edits the data to be edited in accordance with the execution code.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: May 21, 2019
    Assignees: TOKYO INSTITUTE OF TECHNOLOGY, JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventor: Hiroshi Deguchi
  • Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same
    Patent number: 10293330
    Abstract: The present disclosure is directed to novel crystalline germanosilicate compositions and methods of producing the same. In particular, the crystalline germanosilicate compositions are extra-large-pore compositions, designated CIT-13 possessing 10- and 14-membered rings. The disclosure describes methods of preparing these compositions using substituted benzyl-imidazolium organic structure-directing agents (OSDAs). Also disclosed are methods of using these crystalline compositions.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 21, 2019
    Assignee: California Institute of Technology
    Inventors: Joel E. Schmidt, Mark E. Davis, Ben W. Boal, Jong Hun Kang
  • Microbial production of renewable glycolate
    Patent number: 10294481
    Abstract: Some aspects provide engineered microbes for glycolate production. Methods for microbe engineering and culturing are also provided herein. Such engineered microbes exhibit greatly enhanced capabilities for glycolate production.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: May 21, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Gregory Stephanopoulos, Zheng-Jun Li, Brian Pereira
  • Acoustic-assisted iterative wave form optimization for deep tissue focusing
    Patent number: 10292589
    Abstract: A method, apparatus, and article of manufacture for irradiating one or more targets within a sample with electromagnetic (EM) radiation. One or more targets within the sample are controllably defined with an acoustic field. The sample is irradiated with input EM radiation having an input wavefront. An amount of frequency shifted EM radiation is detected, wherein at least some of the input EM radiation that passes through the acoustic field at the targets is shifted in frequency to form the frequency shifted EM radiation. The input wavefront is modified, using feedback comprising the amount of the frequency shifted EM radiation that is detected, into a modified wavefront. The sample is irradiated using the input EM radiation comprising the modified wavefront, and the process is repeated as desired.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: May 21, 2019
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Ying Min Wang, Changhuei Yang
  • Flexible and implantable glucose fuel cell
    Patent number: 10297835
    Abstract: A glucose fuel cell for reception into a given constrained volume of implantation in a vertebrate in which the glucose fuel cell has access to fluid containing glucose. The fuel cell includes an anode adapted to oxidize the glucose, a cathode adapted to reduce an oxidant, and a membrane disposed between the anode and the cathode and separating the anode from the cathode. At least one of the anode or cathode define a flexible sheet that is geometrically deformed to be receivable into the given constrained volume of implantation and increase volumetric power density. Related methods of making a glucose fuel cell of this type and implantable assemblies including the glucose fuel cell are also disclosed.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: May 21, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Rahul Sarpeshkar, Jeremy Bert Muldavin, Todd Addison Thorsen, Jakub Kedzierski, Benjamin Isaac Rapoport, Michale Sean Fee
  • Event monitoring dosimetry apparatuses and methods thereof
    Patent number: 10292445
    Abstract: A dosimetry apparatus includes at least one sensor in a housing, a cover configured to permit compression waves to pass through, the cover is seated over the at least one sensor, and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the at least one sensor; storing the readings with a time and date stamp when obtained; conducting an analysis based on the obtained readings; and outputting at least one of the stored readings or the conducted analysis.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: May 21, 2019
    Assignee: ROCHESTER INSTITUTE OF TECHNOLOGY
    Inventors: David A. Borkholder, Werner Fassler, Andrew Blair, Kim Sherman, Derek DeBusschere
  • Method and system for contactless detection of cardiac activity
    Patent number: 10292594
    Abstract: A system and method include contactless detecting and tracking cardiac activity by making use of a feedback control system, such as a Phase Locked Loop (PLL), in real-time or from a prerecorded signal stream.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: May 21, 2019
    Assignee: ROCHESTER INSTITUTE OF TECHNOLOGY
    Inventors: Gill R. Tsouri, Sohail Dianat
  • Articles and methods for reducing hydrate adhesion
    Patent number: 10294756
    Abstract: This invention relates generally to articles, devices, and methods for gas hydrate mitigation in deep-sea drilling applications. In certain embodiments, hydrate-phobic surfaces are provided that ensure passive enhancement of flow assurance and prevention of catastrophic failures in deep-sea oil and gas operations.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: May 21, 2019
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: J. David Smith, Kripa K. Varanasi, Gareth H. McKinley, Robert E. Cohen, Adam J. Meuler, Harrison L. Bralower
  • Dielectric structures for nitride semiconductor devices
    Patent number: 10297456
    Abstract: A dielectric structure for a nitride semiconductor device and a method of forming the same. A semiconductor device includes at least one semiconductor layer. The at least one semiconductor layer includes a gallium nitride semiconductor material. The semiconductor device also includes an oxidized layer disposed over the at least one semiconductor layer. The oxidized layer includes an oxidized form of the gallium nitride semiconductor of the at least one semiconductor layer. A silicon oxide layer is disposed over the oxidized layer. A gate is disposed over the silicon oxide layer.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: May 21, 2019
    Assignee: Massachusetts Institute of Technology
    Inventors: Bernard A. Alamariu, Omair I. Saadat, Tomas Apostol Palacios
  • Emitter for dissociating gas molecules using non-linear quantum dissonance
    Patent number: 10299364
    Abstract: This disclosure relates generally to an emitter for dissociating exhaust gases on a molecular level into their respective elemental constituents. The emitter includes a palladium plated anode and a cathode, at least a portion of which is palladium plated. When properly powered, the emitters create a non-linear quantum dissonance field to dissociate molecules in exhaust.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: May 21, 2019
    Assignee: Nova Institute of Technology, Inc.
    Inventors: David Yurth, Kevin Collier, Michael Kralik, Colin Wonfor
  • Cognitive radio method and apparatus for achieving ad hoc interference multiple access wireless communication
    Patent number: 10299281
    Abstract: In a radio network having a plurality of first users on channel (FUOCs) and one or more second users on channel (SUOCs), a method and apparatus for a SUOC to select a channel to co-occupy based upon a “selfish” goal of achieving a desired SUOC rate and an “altruistic” goal of causing low-impact on the FUOC. A SUOC collects signal parameters for a plurality of FUOCs, orders the FUOCs based upon different criteria, and attempts to co-exist with FUOCs until a suitable FUOC channel is found.
    Type: Grant
    Filed: June 16, 2015
    Date of Patent: May 21, 2019
    Assignee: Massachusetts Institute of Technology
    Inventor: Rachel E. Learned
  • Apparatus, system and method for medical analyses of seated individual
    Patent number: 10292658
    Abstract: Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: May 21, 2019
    Assignee: Rochester Institute of Technology
    Inventors: David A. Borkholder, Nicholas J. Conn, Masoumeh Haghpanahi
  • DEVICES AND TECHNIQUES FOR INTEGRATED OPTICAL DATA COMMUNICATION
    Publication number: 20190149240
    Abstract: Devices and techniques for integrated optical data communication. A method of encoding symbols in an optical signal may include encoding a first symbol by injecting charge carriers, at a first rate, into a semiconductor device, such as a PIN diode. The method may also include encoding a second symbol by injecting charge carriers, at a second rate, into the semiconductor device. The first rate may exceed the second rate. A modulator driver circuit may include a resistive circuit coupled between supply terminal and drive terminals. The modulator driver circuit may also include a control circuit coupled between a data terminal and the resistive circuit. The control circuit may modulate a resistance of the resistive circuit by selectively coupling one or more of a plurality of portions of the resistive circuit to the drive terminal based on data to be optically encoded.
    Type: Application
    Filed: October 3, 2018
    Publication date: May 16, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Benjamin Roy Moss, Jason Scott Orcutt, Vladimir Marko Stojanovic
  • MAX BINDERS AS MYC MODULATORS AND USES THEREOF
    Publication number: 20190144466
    Abstract: The present disclosure provides compounds of Formula (I?), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxi1 (e.g., inhibitors of Myc, Mad, or Mxi1), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits.
    Type: Application
    Filed: October 22, 2018
    Publication date: May 16, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Angela N. Koehler, Eric Stefan, Francisco Caballero, Dylan Vijith Neel, Nicholas B. Struntz, Helen L. Evans, Andrew Chen
  • SYSTEMS AND METHODS FOR GAZE TRACKING FROM ARBITRARY VIEWPOINTS
    Publication number: 20190147607
    Abstract: A system for determining the gaze direction of a subject includes a camera, a computing device and a machine-readable instruction set. The camera is positioned in an environment to capture image data of head of a subject. The computing device is communicatively coupled to the camera and the computing device includes a processor and a non-transitory computer-readable memory. The machine-readable instruction set is stored in the non-transitory computer-readable memory and causes the computing device to: receive image data from the camera, analyze the image data using a convolutional neural network trained on an image dataset comprising images of a head of a subject captured from viewpoints distributed around up to 360-degrees of head yaw, and predict a gaze direction vector of the subject based upon a combination of head appearance and eye appearance image data from the image dataset.
    Type: Application
    Filed: October 12, 2018
    Publication date: May 16, 2019
    Applicants: Toyota Research Institute, Inc., Massachusetts Institute of Technology
    Inventors: Simon Stent, Adria Recasens, Antonio Torralba, Petr Kellnhofer, Wojciech Matuski
  • METHODS FOR PRODUCING ALLOY DEPOSITS AND CONTROLLING THE NANOSTRUCTURE THEREOF USING NEGATIVE CURRENT PULSING ELECTRO-DEPOSITION, AND ARTICLES INCORPORATING SUCH DEPOSITS
    Publication number: 20190145016
    Abstract: Bipolar wave current, with both positive and negative current portions, is used to electrodeposit a nanocrystalline grain size deposit. Polarity Ratio is the ratio of the absolute value of the time integrated amplitude of negative polarity current and positive polarity current. Grain size can be precisely controlled in alloys of two or more chemical components, at least one of which is a metal, and at least one of which is most electro-active. Typically, although not always, the amount of the more electro-active material is preferentially lessened in the deposit during times of negative current. The deposit also exhibits superior macroscopic quality, being relatively crack and void free.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Andrew J. Detor, Christopher A. Schuh
  • METHODS FOR IDENTIFYING AND MODULATING IMMUNE PHENOTYPES
    Publication number: 20190144942
    Abstract: The present invention provides tools and methods for the systematic analysis of genetic interactions in immune cells. The present invention provides tools and methods for modulating immune cell phenotypes and compositions, combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
    Type: Application
    Filed: February 22, 2017
    Publication date: May 16, 2019
    Applicants: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE GENERAL HOSPITAL CORPORATION
    Inventors: Alexander K. SHALEK, Kellie E. KOLB, Michael B. COLE, Nir YOSEF, Enrique Martin GAYO, Zhengyu OUYANG, Xu YU