Abstract: An optical neural network is constructed based on photonic integrated circuits to perform neuromorphic computing. In the optical neural network, matrix multiplication is implemented using one or more optical interference units, which can apply an arbitrary weighting matrix multiplication to an array of input optical signals. Nonlinear activation is realized by an optical nonlinearity unit, which can be based on nonlinear optical effects, such as saturable absorption. These calculations are implemented optically, thereby resulting in high calculation speeds and low power consumption in the optical neural network.
Type:
Grant
Filed:
May 4, 2022
Date of Patent:
February 27, 2024
Assignee:
Massachusetts Institute of Technology
Inventors:
Jacques Johannes Carolan, Mihika Prabhu, Scott A. Skirlo, Yichen Shen, Marin Soljacic, Dirk Englund, Nicholas C. Harris
Abstract: Systems and methods for performing high-speed geofencing in accordance with various embodiments of the invention are disclosed. One embodiment includes a robotics platform including a set of one or more motors, at least one sensor, a controller comprising a set of one or more processors, and a memory containing a controller application and a backup controller application, wherein the controller application configures the set of processors to control the robotics platform by performing the steps of receiving user commands, generating commands controlling the set of one or more motors based on the received commands.
Abstract: A device including a programmable photonic processor configured to operate on optical pulses to perform computational sequences of linear operations and nonlinear operations each based on a parametric nonlinear optical process; a memory coupled to the processor and programmable to store or accumulate the analog optical pulse amplitudes of the optical pulses; a control circuit controlling the transfer of the analog optical pulse amplitudes between the processor and the memory according to a computation schedule; and wherein information is multiplexed in time by encoding the information onto the analog optical pulse amplitudes of the optical pulses occupying time bins at a fixed repetition rate such that the optical pulses, occupying different ones of the time bins, can be made to interact using appropriate temporal delays.
Type:
Application
Filed:
August 11, 2023
Publication date:
February 22, 2024
Applicant:
California Institute of Technology
Inventors:
Gordon H.Y. Li, Midya Parto, Ryoto Sekine, James Williams, Christian Leefmans, Alireza Marandi
Abstract: A retrographic sensor includes a transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. One or more excitation light sources emit light toward a side surface of the transparent structure. The side surface may include a fluorescent layer, where the light from the one or more excitation light sources excites fluorescent emissions from the fluorescent layer. The fluorescent emissions may illuminate the at least partially reflective layer.
Abstract: Disclosed herein is a wearable article, comprising a fabric. In some embodiments, the fabric comprises an inner material layer which forms an inner surface of the wearable article, an outer material layer which forms an outer surface of the wearable article; and one or more intermediate material layers disposed between the inner and outer material layers. In some embodiments, the inner, outer, and one or more intermediate material layers are knitted together to provide a combination of two or more of: two or more compression zones; two or more mobility zones; two or more materials; or one or more electronic components.
Type:
Application
Filed:
August 21, 2023
Publication date:
February 22, 2024
Applicant:
Massachusetts Institute of Technology
Inventors:
Dava J. NEWMAN, Skylar TIBBITS, Hugh M. HERR, Svetlana BORISKINA, Lavender TESSMER, Volodymyr KOROLOVYCH, Atharva SAHASRABUDHE, Ganit GOLDSTEIN, Jesus Guillermo HERRERA ARCOS, Rachel BELLISLE, Cody PAIGE, Christopher SHALLAL
Abstract: A device, comprising a base, and a plurality of microneedles attached to the base, wherein the microneedles comprise dehydrated honey having water content of less than 5% by weight. The dehydrated honey can be a Manuka dehydrated honey. Also disclosed are methods of fabricating and using the disclosed device.
Type:
Grant
Filed:
June 5, 2020
Date of Patent:
February 20, 2024
Assignee:
Massachusetts Institute of Technology
Inventors:
Galit Frydman, David Olaleye, Illina Yang, Damodaran Annamalai
Abstract: The present invention generally relates to a controlled fluidic device to develop spatially complex environments to enhance the rate of evolution in cell populations. The method further provides an enhanced understanding in the emergence, for example, drug resistance during cancer chemotherapy.
Type:
Grant
Filed:
October 28, 2016
Date of Patent:
February 20, 2024
Assignees:
The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard
College, Dana-Farber Cancer Institute, Inc.
Inventors:
Anindita Basu, Christopher B. Ford, Aviv Regev, David A. Weitz, Asaf Rotem, Kevin Struhl
Abstract: A protective layer can be deposited on a surface of an porous polymer separator placing on a Li-metal electrode to protect against adverse electrochemical activity in a battery. The protective layer can be a multilayered structure including graphene oxide.
Abstract: Systems and methods for developing tough hypoeutectic amorphous metal-based materials for additive manufacturing, and methods of additive manufacturing using such materials are provided. The methods use 3D printing of discrete thin layers during the assembly of bulk parts from metallic glass alloys with compositions selected to improve toughness at the expense of glass forming ability. The metallic glass alloy used in manufacturing of a bulk part is selected to have minimal glass forming ability for the per layer cooling rate afforded by the manufacturing process, and may be specially composed for high toughness.
Type:
Grant
Filed:
November 29, 2021
Date of Patent:
February 20, 2024
Assignee:
California Institute of Technology
Inventors:
Douglas C. Hofmann, Andre M. Pate, Scott N. Roberts
Abstract: Active cantilever probes having a thin coating incorporated into their design are disclosed. The probes can be operated in opaque and/or chemically harsh environments without the need of a light source or optical system and without being significantly negatively impacted by corrosion. The probes include a substrate that has a cantilever, a thermomechanical actuator associated with the cantilever, a piezoresistive stress sensor disposed on the cantilever, and a thin coating disposed on the cantilever and the piezoresistive stress sensor. The coating is bonded to the substrate, is thermally conductive, and has a low thermal resistance. Further, the thin coating is configured to have little to no impact on one or more of a mass of the active probe, a residual stress of the cantilever, or a stiffness of the active probe. Techniques for performing topography and making other measurements in an opaque and/or chemically harsh environment are also provided.
Type:
Grant
Filed:
July 6, 2020
Date of Patent:
February 20, 2024
Assignees:
Massachusetts Institute of Technology, Nano Analytik GMBH, Synsfuels Americas Corporation
Inventors:
Fangzhou Xia, Chen Yang, Yi Wang, Kamal Youcef-Toumi, Christoph Reuter, Tzvetan Ivanov, Mathias Holz, Ivo Rangelow
Abstract: The invention, in part, includes methods of single molecule protein sequencing that include using weak binding spectra in the amino acid identification.
Type:
Grant
Filed:
May 25, 2022
Date of Patent:
February 20, 2024
Assignee:
Massachusetts Institute of Technology
Inventors:
Edward Boyden, Adam Henry Marblestone, Samuel Gordon Rodriques
Abstract: Autonomous systems for control of heavy object tumbling and related methods are generally described. In some embodiments, the autonomous system may include one or more tethers connected to a heavy object, each tether position and location controlled by one or more actuators. The control system may include one or more processors in communication with the actuators to maintain constant quasi-static control of the heavy object during a tumbling process, in which the object is manipulated (e.g., rotated about an axis relative to a supporting surface) to provide access to alternate faces of the object. In some embodiments, the control system may reduce the risk of uncontrollable tumbling by alternating between position and tension control of the tethers depending on the orientation of the object and/or progression of the tumbling process.
Abstract: Disclosed is a method of reducing surface unevenness of a semiconductor wafer (100). In a preferred embodiment, the method comprises: removing a portion of a deposited layer and a protective layer thereon using a first slurry to provide an intermediate surface (1123). In the described embodiment, the deposited layer includes an epitaxial layer (112) and the protective layer includes a first dielectric layer (113). The first slurry includes particles with a hardness level the same as or exceeding that of the epitaxial layer (112). A slurry for use in wafer fabrication for reducing surface unevenness of a semiconductor wafer is also disclosed.
Type:
Grant
Filed:
February 19, 2019
Date of Patent:
February 13, 2024
Assignees:
Massachusetts Institute of Technology, Nanyang Technological University, National University of Singapore
Inventors:
Li Zhang, Kwang Hong Lee, Keith Cheng Yeow Ng, Kenneth Eng Kian Lee, Eugene A. Fitzgerald, Soo Jin Chua, Chuan Seng Tan
Abstract: The present invention provides point-of-care blood typing devices. The devices require only a small sample of blood and are able to provide results within minutes. The devices are capable of identifying A, B, AB, and O type blood. The devices are also capable of identifying blood that is positive (+) or negative (?) for the D antigen.
Type:
Grant
Filed:
October 7, 2020
Date of Patent:
February 13, 2024
Assignee:
University of Rochester, Rochester Institute of Technology
Abstract: By irradiating target liquid L containing fine bubbles with ultrasonic waves from an ultrasonic irradiation device 102, the fine bubbles in the target liquid L is reduced. By irradiating the target liquid L with ultrasonic waves, fine bubbles in the target liquid L can be reduced effectively. By using ultrasonic waves, bubbles with small diameters, particularly fine bubbles, can be effectively reduced, so that fine bubbles in the target liquid L can be efficiently reduced.
Type:
Grant
Filed:
November 29, 2018
Date of Patent:
February 13, 2024
Assignees:
Shimadzu Corporation, National Institute of Technology and Evaluation, Fine Bubble Industries Association
Abstract: Techniques are disclosed for an adaptive and causal random linear network coding (AC-RLNC) with forward error correction (FEC) for a communication channel with delayed feedback. An example methodology implementing the techniques includes transmitting one or more coded packets in a communication channel, determining a channel behavior of the channel, and adaptively adjusting a transmission of a subsequent coded packet in the first channel based on the determined channel behavior. The communication channel may be a point-to-point communication channel between a sender and a receiver. The channel behavior may be determined based on feedback acknowledgements provided by the receiver. The subsequent coded packet may be a random linear combination of one or more information packets.
Abstract: Vehicles having the versatility to be used as farm vehicles while also being able to be used as a transportation method, such as a motorcycle, are provided. The vehicles can generally include a three-wheel configuration in which first and second drive wheels are substantially vertically aligned, and the third wheel is offset from the vertically aligned drive wheels. The third wheel can be aligned with the second wheel, or it can be disposed at a location that is between the first and second wheels while still being offset from the vertical alignment. A tool for performing farming actions is also provided. In some instances the tool can be laterally offset from the vertically aligned wheels, located between the drive wheels, while in other instances the tool can be disposed distal of the rear wheel. Many vehicle and tool configurations are disclosed, as are methods for operating the same.
Type:
Grant
Filed:
April 27, 2020
Date of Patent:
February 13, 2024
Assignee:
Massachusetts Institute of Technology
Inventors:
Guillermo Fabian Diaz Lankenau, Amos Greene Winter, V
Abstract: Provided are engineered phages populations, which are homogeneous in length, as well as methods of making and methods of using such phages. Also provided are engineered chlorotoxin-phages as well as their methods of making and using. The disclosed homogeneous phage populations and chlorotoxin-phages may be used, for example, for treating and/or imaging tumors, such as central nervous system tumors.
Type:
Grant
Filed:
March 22, 2021
Date of Patent:
February 13, 2024
Assignee:
Massachusetts Institute of Technology
Inventors:
Angela M. Belcher, Uyanga Tsedev, Fred Lam
Abstract: Provided is a method and a composition for improving behavioral performance in an individual comprising identifying an individual in need of treatment, and providing such an individual a composition comprising bacteria within the genus Bacteroides.
Type:
Grant
Filed:
July 22, 2020
Date of Patent:
February 13, 2024
Assignee:
California Institute of Technology
Inventors:
Sarkis K Mazmanian, Paul H Patterson, Janet Chow, Elaine Hsiao, Sara W McBride