Abstract: A Ti—Ni-based alloy, which has a torsion angle for Interface I that is a junction plane between habit plane variants of a martensitic phase, of less than 1.00°; a wire, an electrically conductive actuator, and a temperature sensor, each of which uses that alloy; and a method of producing the Ti—Ni-based alloy.
Type:
Grant
Filed:
December 31, 2019
Date of Patent:
April 26, 2022
Assignees:
FURUKAWA TECHNO MATERIAL CO., LTD., TOKYO INSTITUTE OF TECHNOLOGY, FURUKAWA ELECTRIC CO., LTD.
Abstract: Components with relatively high loading of active pharmaceutical ingredients are generally provided. In some embodiments, the component (e.g., a tissue interfacing component) comprises a solid therapeutic agent and a supporting material such that the solid therapeutic agent is present in the component in an amount of greater than or equal to 10 wt % versus the total weight of the tissue interfacing component. Such tissue-interfacing components may be useful for delivery of API doses e.g., to a subject. Advantageously, in some embodiments, the reduction of volume required to deliver the required API dose as compared to a liquid formulation permits the creation of solid needle delivery systems for a wide variety of drugs in a variety of places/tissues (e.g., tongue, GI mucosal tissue, skin) and/or reduces and/or eliminates the application of an external force in order to inject a drug solution through the small opening in the needle.
Type:
Grant
Filed:
May 17, 2018
Date of Patent:
April 26, 2022
Assignees:
Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
Inventors:
Carlo Giovanni Traverso, Alex G. Abramson, Ester Caffarel Salvador, Niclas Roxhed, Minsoo Khang, Taylor Bensel, Robert S. Langer
Abstract: Disclosed in the present invention is a fishway effect evaluation method based on stable isotope method, belonging to the technical field of fishway effect evaluation. The fishway effect evaluation method according to the present invention comprises stable isotope ratio determination, trophic niche estimation and effectiveness evaluation on fishway construction. The evaluation method according to the present invention is used for researching one or more migratory fishes in the upstream and downstream of the water conservancy projects, determining and quantitatively explaining whether the influence of the water conservancy projects on one or more migratory fishes is eliminated or not from the perspective of the ecosystem through comparison and analysis of stable isotopes, and has the characteristics of high detection speed, stable result and the like.
Type:
Grant
Filed:
January 25, 2021
Date of Patent:
April 26, 2022
Assignee:
TIANJIN RESEARCH INSTITUTE FOR WATER TRANSPORT ENGINEERING, M.O.T.
Abstract: Disclosed herein is an image encoding/decoding method. The method of decoding the image includes structuring a motion information candidate list of a current block, selecting a first motion information candidate used for prediction of a first subblock in the current block from the motion information candidate list, selecting a second motion information candidate used for prediction of a second subblock in the current block from the motion information candidate list, generating a prediction sample of the first subblock by performing inter prediction with respect to the first subblock based on the first motion information candidate, and generating a prediction sample of the second subblock by performing inter prediction with the second subblock based on the second motion information candidate.
Type:
Application
Filed:
February 21, 2020
Publication date:
April 21, 2022
Applicants:
Electronics and Telecommunications Research Institute, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
Inventors:
Jung Won KANG, Ha Hyun LEE, Sung Chang LIM, Jin Ho LEE, Hui Yong KIM, Gwang Hoon PARK, Tae Hyun KIM, Dae Young LEE
Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
Type:
Application
Filed:
September 27, 2021
Publication date:
April 21, 2022
Applicants:
The United States of America as represented by the Department of Veterans Affairs, Schepens Eye Research Institute, Children's Medical Center Corporation
Inventors:
Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
Abstract: Provided are an igniter-integrated thrust chamber for a rocket engine using a cryogenic fuel and liquid oxygen and a rocket including the thrust chamber. The thrust chamber includes a combustion chamber and a mixing head assembly, which is disposed at one side of the combustion chamber and is integrated with the combustion chamber.
Abstract: The present invention discloses a same-cavity integrated vertical high-speed multistage superfine pulverizing device and method for walnut shells. The same-cavity integrated vertical high-speed multistage superfine pulverizing device for walnut shells includes a double-channel sliding type feeding device and a same-cavity integrated vertical pulverizing device. The same-cavity integrated vertical pulverizing device includes a material lifting disc and a same-cavity integrated vertical pulverizing barrel. A first-stage coarse crushing region, a second-stage fine crushing region, a third-stage pneumatic impact micro pulverizing region and a fourth-stage airflow mill superfine pulverizing region are disposed in the same-cavity integrated vertical pulverizing barrel.
Type:
Application
Filed:
May 9, 2020
Publication date:
April 21, 2022
Applicants:
QINGDAO UNIVERSITY OF TECHNOLOGY, RESEARCH INSTITUTE OF AGRICULTURAL MECHANIZATION, XINJIANG ACADEMY OF AGRICULTURAL SCIENCES, XINJIANG JIANG NING LIGHT INDUSTRIAL MACHINERY ENGINEERING TECHNOLOGY CO., LTD.
Abstract: The poly(pro-drug) material includes one or more alternating therapeutic compounds and biodegradable hydrocarbyl groups. The therapeutic compounds and biodegradable hydrocarbyl groups are separated by cleavable linker compounds. The therapeutic compounds, such as estrogen, curcumin, and fingolimod, include a plurality of substitutable functional groups that provide reaction sites for complexing with the cleavable linkers and in turn one or more polymers, such that the poly(pro-drug) material ends up composed of the therapeutic compound itself. In aqueous media and at physiological temperature and pH, the poly(pro-drug) materials degrade to release the therapeutic compounds from the material with a zero-order release profile, Advantageously, the poly(pro-drug) materials release the therapeutic compounds on time scales of years. The poly(pro-drug) materials also exhibit reduced to allow for prolonged implantation within a patient.
Type:
Application
Filed:
November 1, 2021
Publication date:
April 21, 2022
Applicant:
RENSSELAER POLYTECHNIC INSTITUTE
Inventors:
Edmund Francis PALERMO, Anthony Richard D'AMATO, Ryan J. GILBERT, Samuel Ellman
Abstract: A method for slice-based access barring and a user equipment are provided. The method includes: acquiring, by the non-access stratum, a unicasted non-access stratum signalling, wherein the unicasted non-access stratum signalling comprises an access category definition corresponding to a network slice; acquiring, by the access stratum, broadcasted system information, wherein the broadcasted system information comprises a local access category definition corresponding to the network slice; delivering, by the access stratum, the local access category definition to the non-access stratum; initiating, by the non-access stratum, an access attempt; determining, by the non-access stratum, an access category of the access attempt according to the access category definition and the local access category definition; and performing, by the access stratum, an access barring check for the access attempt according to the access category.
Type:
Application
Filed:
September 12, 2021
Publication date:
April 21, 2022
Applicant:
Industrial Technology Research Institute
Abstract: The present disclosure relates to a composition for preventing, alleviating or treating depression or anxiety disorder, which contains Lactobacillus sakei as an active ingredient. The Lactobacillus sakei strain according to the present disclosure can be used to prevent, alleviate or treat a mental disorder such as depression or anxiety disorder.
Type:
Application
Filed:
February 20, 2020
Publication date:
April 21, 2022
Applicant:
KOREA FOOD RESEARCH INSTITUTE
Inventors:
Hak Jong CHOI, Nam Hee KIM, Hyo Kyeong PARK, Ji Eun LEE
Abstract: A chip-scale mode-locked laser including a cavity including a gain medium for amplifying signal electromagnetic radiation (signal) through stimulated emission, the signal comprising a signal wavelength; and a passive or active mode-locking device to enforce pulse formation in the laser. The mode-locking device includes a thin-film waveguide having a thickness on the order of the signal wavelength so as to confine and guide the signal along the thin-film waveguide, and a material comprising a second-order nonlinear susceptibility to enable active or passive mode-locking of the signal. The mode-locking device leads to generation of pulses of the signal outputted from the mode-locked laser.
Abstract: An image decoding method, according to the present invention, includes the steps of: deriving an MPM candidate mode from neighboring blocks adjacent to a target block to be decoded; generating an MPM list using the MPM candidate mode derived from the neighboring blocks; and deriving an intra prediction mode for the target block to be decoded using the generated MPM list. According to the present invention, image compression efficiency can be improved.
Type:
Application
Filed:
January 3, 2022
Publication date:
April 21, 2022
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jin Ho LEE, Hui Yong KIM, Sung Chang LIM, Jin Soo CHOI, Jin Woong KIM
Abstract: The present invention relates to an Aspergillus niger F22 strain having a nematicidal activity against plant-parasitic nematodes; a nematicidal microorganism agent against plant-parasitic nematodes, containing, as an active ingredient, the strain, a spore, a fungal hyphal mass, or a culture liquid thereof; a method for controlling plant-parasitic nematodes, having a step of administering the microorganism agent to a crop, a crop seed, or a field; and a method for preparation of a nematicidal microorganism agent against plant-parasitic nematodes, having a step of culturing the strain.
Type:
Application
Filed:
January 4, 2022
Publication date:
April 21, 2022
Applicants:
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Inventors:
Jin Cheol KIM, Hun KIM, Kee-Sun SHIN, Ja Yeong JANG, Gyung Ja CHOI, Yong Ho CHOI, Kyoung Soo JANG, Mi Bang KIM
Abstract: This disclosure relates to an apparatus and methods for applying X-ray reflectometry (XRR) in characterizing three dimensional nanostructures supported on a flat substrate with a miniscule sampling area and a thickness in nanometers. In particular, this disclosure is targeted for addressing the difficulties encountered when XRR is applied to samples with intricate nanostructures along all three directions, e.g. arrays of nanostructured poles or shafts. Convergent X-ray with long wavelength, greater than that from a copper anode of 0.154 nm and less than twice of the characteristic dimensions along the film thickness direction, is preferably used with appropriate collimations on both incident and detection arms to enable the XRR for measurements of samples with limited sample area and scattering volumes. In one embodiment, the incident angle of the long-wavelength focused X-ray is ?24°, and the sample area is ?25 ?m×25 ?m.
Type:
Application
Filed:
November 22, 2021
Publication date:
April 21, 2022
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The present invention, which is a food composition for alleviating diabetes that contains Schisandra chinensis fruit water and bean juice as active ingredients, has a high inhibitory activity against ?-glucosidase and prevents a rise of the blood sugar after meals, thereby alleviating diabetes. The food composition for alleviating diabetes can be prepared in different forms, such as soy milk, powdered soy milk, other forms of soy milk, or processed bean curd, and used in the preparation of health functional foods for blood sugar control or foods for diabetics according to the Special Purpose Foods of the general foods. In addition, the food composition for alleviating diabetes according to the present invention, when further containing a saccharified material of grain, maintains viscosity similar to that of regular soy milk by preventing agglomeration of the liquid soy milk and improves sensory properties, so it can be suitable for use in beverages such as soy milk or other forms of soy milk.
Type:
Application
Filed:
November 13, 2019
Publication date:
April 21, 2022
Applicant:
KOREA FOOD RESEARCH INSTITUTE
Inventors:
Dai Ja JANG, Hye Jeong YANG, Min Jung KIM, Yu Jin KIM
Abstract: The present disclosure relates to the technical field of rails welding, and particularly to a method for optimizing microstructure of a rail welded joint, the method comprises the following steps: step 1): subjecting a rail web area of a to-be-cooled welded joint which is obtained by flash butt welding to an accelerated cooling by means of an accelerated cooling device and by using compressed air as a cooling medium, measuring and monitoring temperature of a central position of the rail web of the welded joint while cooling; step 2): stopping the accelerated cooling when the temperature of the central position of the rail web drops to a preset temperature, then placing the welded joint in air and naturally cooling to room temperature, wherein the rail is a pearlite rail having a carbon content of 0.6-0.9 wt %.
Type:
Application
Filed:
September 16, 2021
Publication date:
April 21, 2022
Applicant:
PanGang Group Panzhihua Iron & Steel Research Institute Co., Ltd.
Abstract: Disclosed is a method for selecting a potential subject with benefiting from a pharmaceutical composition for treating or preventing cancer, comprising: determining the presence or absence of a mutation in tumor protein p53 (TP53) gene and/or BCL6 co-repressor (BCOR) gene by using a sample collected from the subject; and providing an indication that the subject is a potential subject with benefiting from the pharmaceutical composition in the case of TP53 wild type and/or BCOR wild type.
Type:
Application
Filed:
February 27, 2020
Publication date:
April 21, 2022
Applicants:
Sumitomo Dainippon Pharma Co., Ltd., International Institute of Cancer Immunology, Inc.
Abstract: Logical rules can be automatically generated for use with event detection systems according to some aspects of the present disclosure. For example, a computing device can extract a group of logical rules from trained decision trees and apply a test data set to the group of logical rules to determine count values corresponding to the logical rules. The computing device can then determine performance metric values based on the count values, select a subset of logical rules from among the group of logical rules based on the performance metric values, and provide at least one logical rule in the subset for use with an event detection system. The event detection system can be configured to detect an event in relation to a target data set that was not used to train the decision trees.
Type:
Application
Filed:
April 8, 2021
Publication date:
April 21, 2022
Applicant:
SAS Institute Inc.
Inventors:
Hamoon Azizsoltani, Prathaban Mookiah, Weichen Wang, Thomas J. O'Connell