Patents Assigned to INSTITUTE
  • Patent number: 11266313
    Abstract: A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.
    Type: Grant
    Filed: February 6, 2015
    Date of Patent: March 8, 2022
    Assignees: Massachusetts Institute of Technology, Duke University
    Inventors: Moungi G. Bawendi, Jorge M. Ferrer, W. David Lee, Lisa F. Marshall, David G. Kirsch
  • Patent number: 11269203
    Abstract: Polarization-independent focusing is advantageously achieved by a multifocal system having a polarization beam splitter (PBS) to split an unpolarized light beam into two orthogonally linearly-polarized (LP) light beams. The two LP light beams are reflected by mirrors to travel in opposite directions and enter into a variable-focusing module at two ends thereof, respectively. The module includes waveplates to convert the LP light beams into two circularly-polarized (CP) light beams at both ends of an optical assembly. The optical assembly is formed with a stack of birefringent optical elements including at least one geometric phase lens and one polarization selector that may be electrically modulated to select the optical power in focusing the two CP light beams. Followed by the waveplates converting two focused CP light beams to two focused LP light beams and upon mirror reflection, the beams are finally recombined by the PBS to form one focused light beam.
    Type: Grant
    Filed: January 23, 2020
    Date of Patent: March 8, 2022
    Assignee: Hong Kong Applied Science and Technology Institute Company Limited
    Inventors: Ming Wai Alwin Tam, Xiaohan Wang, Zhuanyun Zhang, Xiuling Zhu, Kin Lung Kenny Chan
  • Patent number: 11267742
    Abstract: A built-in micro-interface papermaking wastewater treatment system and a treatment method are provided in the present invention. The treatment system includes a papermaking wastewater tank, a grid cleaner, an adjustment tank, a centrifugal filter and a sedimentation tank which are connected in sequence, and further includes a heat exchanger, a preheater, a wet oxidation reactor, a gas-liquid separator and a biodegradation tank. A micro-interface unit for dispersing and crushing gas into gas bubbles is disposed inside the wet oxidation reactor. The micro-interface unit includes a pneumatic micro-interface generator, a gas inlet is disposed at a side wall of the wet oxidation reactor, and the gas inlet extends to an interior of the pneumatic micro-interface generator through a pipeline. By arranging the micro-interface unit inside the wet oxidation reactor of the treatment system, the consumption of air or oxygen can be reduced, which realizes low energy consumption and high treatment efficiency.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: March 8, 2022
    Assignee: NANJING YANCHANG REACTION TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Zhibing Zhang, Zheng Zhou, Feng Zhang, Lei Li, Weimin Meng, Baorong Wang, Gaodong Yang, Huaxun Luo, Guoqiang Yang, Hongzhou Tian, Yu Cao
  • Patent number: 11267789
    Abstract: This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: March 8, 2022
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: Scott P. Runyon, Rangan Maitra, Sanju Narayanan, James Barnwell Thomas
  • Patent number: 11272537
    Abstract: The present invention relates to a wireless communication method and a wireless communication terminal using a determination of basic service set identification information of a received frame, and more particularly, to a wireless communication method and a wireless communication terminal for performing an operation according to a determination result whether the received frame is an intra-BSS frame or an inter-BSS frame.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: March 8, 2022
    Assignees: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., SK TELECOM CO., LTD.
    Inventors: Geonjung Ko, Juhyung Son, Jinsam Kwak, Woojin Ahn
  • Patent number: 11272541
    Abstract: Provided is a method for transmitting, by a transmitter, a first data having periodicity through a channel of an unlicensed band: The transmitter adjusts at least one of transmission timing of the first data and clear channel assessment (CCA) timing for the channel to occupy the channel. The transmitter determines whether the channel may be occupied by performing a CCA on the channel at the CCA timing. The transmitter transmits the first data through the channel at the transmission timing of the first data, when it is determined that the channel may be occupied.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: March 8, 2022
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Eunkyung Kim, Jae Sun Cha, Chanho Yoon, Seung-Kwon Baek, Jae Joon Park, Kwang Jae Lim, Sung Cheol Chang
  • Patent number: 11266695
    Abstract: Methods for the in vitro production of enucleated red blood cells and the enucleated red blood cells thus prepared are provided. Such enucleated red blood cells may express a sortaggable surface protein, which allows for surface modification in the presence of a sortase. Also described herein are surface modified enucleated red blood cells, e.g., conjugated with an agent of interest such as a peptide, a detectable label, or a chemotherapeutic agent, and uses thereof in delivering the agent to a subject.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: March 8, 2022
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Harvey Lodish, Hidde L. Ploegh, Hsiang-Ying Sherry Lee, Jiahai Shi, Lenka Hoffman, Novalia Pishesha
  • Patent number: 11268107
    Abstract: Described herein are vectors, such as adeno-associated virus (AAV) vectors, and recombinant AAV expressing Smad7. The disclosed AAV vectors and rAAV can be used for therapeutic applications in the treatment and amelioration of muscle wasting, cardiac and/or skeletal muscle wasting associated with cancer cachexia.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: March 8, 2022
    Assignees: Washington State University, Baker Heart and Diabetes Institute
    Inventors: Buel Dantese Rodgers, Paul Gregorevic
  • Patent number: 11271157
    Abstract: Provided are a perovskite film and a manufacturing method thereof. The method includes the following steps. A perovskite precursor material is coated in a linear direction on a substrate with a temperature between 100° C. and 200° C., wherein a concentration of the perovskite precursor material is between 0.05 M and 1.5 M. An infrared light irradiation is performed on the perovskite precursor material to cure the perovskite precursor material to form a thin film including a compound represented by formula (1). The perovskite film has a single 2D phase structure or has a structure in which a 3D phase structure is mixed with a single 2D phase structure. (RNH3)2MA(n?1)M1nX(3n+1)??formula (1), wherein the definitions of R, MA, M1, X, and n are as defined above.
    Type: Grant
    Filed: September 29, 2020
    Date of Patent: March 8, 2022
    Assignee: Industrial Technology Research Institute
    Inventors: Kuo-Wei Huang, Yung-Liang Tung, Shih-Hsiung Wu, Jen-An Chen, Pei-Ting Chiu, Yu-Hung Chen
  • Patent number: 11266606
    Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: March 8, 2022
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Arturo J. Vegas, Joshua C. Doloff, Omid Veiseh, Minglin Ma, Robert S. Langer, Daniel G. Anderson
  • Patent number: 11270150
    Abstract: A computing device divides a training image into a plurality of training blocks, and the training image includes a training object. The computing device calculates, for each of the training blocks, a correct confidence score of the training object covering the training block according to an image-marking data and a confidence-score-translating function, and the image-marking data includes a piece of location information of the training object in the training image. Then, the computing device trains a deep-learning model with the training image, the correct confidence scores and the image-marking data to generate the object-detecting model.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: March 8, 2022
    Assignee: INSTITUTE FOR INFORMATION INDUSTRY
    Inventors: Yen-Lin Chen, Hsiu-Chih Chen, Chieh-Min Chang, Chao-Wei Yu, Meng-Tsan Li
  • Patent number: 11267723
    Abstract: A method of purifying a plurality of metal oxide particles produced from a synthesis process comprising the step of washing a plurality of metal oxide particles in a first solvent composition comprising of at least one aliphatic ether, and at least one flocculant. In one embodiment, the plurality of metal oxide particles are iron oxide particles produced from a thermal decomposition synthesis process between an iron-oleate complex and oleic acid in 1-octadecene, wherein the first solvent composition comprises a 1:1 (vol/vol) ratio of an aliphatic ether in the form of diethyl ether and a flocculant in the form of methanol. The washed iron oxide particles are further washed in a second solvent composition comprising a 1:1 (vol/vol) ratio of hexane and ethanol, and then finally dispersed in hexane. The resulting iron oxide particles find use as a contrast agent for magnetic resonance imaging (MRI) or as magnetic particles in magnetic separation, magnetism-directed targeting or magnetism-induced heating.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: March 8, 2022
    Assignee: Royal Melbourne Institute of Technology
    Inventors: Amanda Anderson, Vipul Bansal, Jos Laurie Campbell, Rajesh Ramanathan, Jyoti Arora, Ravi Shukla
  • Patent number: 11268870
    Abstract: A haptic signalizing device comprises a number of piezoelectric elements arranged below a device surface such that mechanical deformations caused by the converse piezoelectric effect in the at least one piezoelectric element make the device surface to move such that the device surface follows the piezoelectric element and a driving circuit configured to cause the converse piezoelectric effect on the at least one piezoelectric element by generating an alternating electric field over the piezoelectric element in a bipolar fashion, that is, consecutively in both the same and the opposite direction with respect to the polarization of the piezoelectric element, to make the piezoelectric element to move beyond its initial position consecutively in both directions.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: March 8, 2022
    Assignee: INSTITUTE OF ENGINEERING THERMOPHYSIC, CHINESE ACADEMY OF SCIENCES
    Inventors: Fan Li, Juan Du, Sichen Wang, Hongwu Zhang, Chaoqun Nie
  • Patent number: 11266338
    Abstract: An automatic depression detection method includes the following steps of: inputting audio and video files, wherein the audio and video files contain original data in both audio and video modes; conducting segmentation and feature extraction on the audio and video files to obtain a plurality of audio segment horizontal features and video segment horizontal features; combining segment horizontal features into an audio horizontal feature and a video horizontal feature respectively by utilizing a feature evolution pooling objective function; and conducting attentional computation on the segment horizontal features to obtain a video attention audio feature and an audio attention video feature, splicing the audio horizontal feature, the video horizontal feature, the video attention audio feature and the audio attention video feature to form a multimodal spatio-temporal representation, and inputting the multimodal spatio-temporal representation into support vector regression to predict the depression level of indivi
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: March 8, 2022
    Assignee: INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES
    Inventors: Jianhua Tao, Mingyue Niu, Bin Liu, Qifei Li
  • Patent number: 11270882
    Abstract: A film formation apparatus is configured to supply mist of a solution to a surface of a substrate so as to epitaxially grow a film on the surface of the substrate. The film formation apparatus may be provided with: a furnace configured to house and heat the substrate; a reservoir configured to store the solution; a heater configured to heat the solution in the reservoir; an ultrasonic transducer configured to apply ultrasound to the solution in the reservoir so as to generate the mist of the solution in the reservoir; and a mist supply path configured to carry the mist from the reservoir to the furnace.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: March 8, 2022
    Assignees: DENSO CORPORATION, NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY
    Inventors: Tatsuji Nagaoka, Hiroyuki Nishinaka, Daisuke Tahara, Masahiro Yoshimoto
  • Patent number: 11270804
    Abstract: In a pressurized water reactor operation method, a fuel assembly including first fuel rods that operates for a preset first operation time and second fuel rods that operates for a second operation time longer than the first operation time is prepared. An operation schedule of a pressurized water reactor is created by mixing the first operation time of the first fuel rods and the second operation time of the second fuel rods. The pressurized water reactor operates by repeating the operation schedule.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: March 8, 2022
    Assignee: ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Deokjung Lee, Eun Jeong, Jiwon Choe, Soo Young Choi, Jinsu Park, Jaerim Jang, Peng Zhang
  • Patent number: 11271426
    Abstract: According to one embodiment of the present disclosure, there is provided a capacitive coupler structure, including: power transmitters, each including a first metal plate and a second metal plate, and power receivers, each including a third metal plate and a fourth metal plate, where the first metal plate and the third metal plate form a first capacitor, the second metal plate and the fourth metal plate form a second capacitor, and each center of gravity of the first metal plate through the fourth metal plate is aligned on a single vertical line, and the first metal plate through the fourth metal plate form capacitive couplings.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: March 8, 2022
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seungyoung Ahn, Chan Jun Park, Jaehyoung Park, Yujun Shin, Sungryul Huh, Bomson Lee
  • Patent number: 11271653
    Abstract: [Problem] To provide a novel optical network which can be used as an in-vehicle optical backbone network and exhibits high capacity, low delay, low power consumption, low noise and low cost.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: March 8, 2022
    Assignee: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
    Inventors: Ryo Takahashi, Tetsuya Kawanishi, Naokatsu Yamamoto
  • Patent number: 11270447
    Abstract: In a convolutional neural network (CNN) using an encoder-decoder structure for image segmentation, a multi-scale context aggregation module receives an encoded final-stage feature map from the encoder, and sequentially aggregates multi-scale contexts of this feature map from a global scale to a local scale to strengthen semantic relationships of contexts of different scales to improve segmentation accuracy. The multi-scale contexts are obtained by computing atrous convolution on the feature map for different dilation rates. To reduce computation, a channel-wise feature selection (CFS) module is used in the decoder to merge two input feature maps. Each feature map is processed by a global pooling layer followed by a fully connected layer or a 1×1 convolutional layer to select channels of high activation. By subsequent channel-wise multiplication and elementwise summation, only channels with high activation in both feature maps are preserved and enhanced in the merged feature map.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: March 8, 2022
    Assignee: Hong Kong Applied Science and Technology Institute Company Limited
    Inventors: Shangping Liu, Lu Wang, Pingping Zhang, Huchuan Lu
  • Patent number: 11267889
    Abstract: The instant disclosure provides antibodies that specifically bind to human CTLA-4 and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: March 8, 2022
    Assignees: Agenus Inc., Ludwig Institute for Cancer Research Ltd., Memorial Sloan-Kettering Cancer Center
    Inventors: Marc Van Dijk, Cornelia Anne Mundt, Gerd Ritter, David Schaer, Jedd David Wolchok, Taha Merghoub, David Adam Savitsky, Nicholas Stuart Wilson