Abstract: Meta-lens based ocular imaging, near-eye display, and eye-tracking systems are described. The systems can include a single focusing optic and an integrated circuit that provides illumination light and includes an imaging array. The focusing optic includes meta-atoms formed on a substrate. The systems may have no moving parts and achieve imaging or image-projection fields-of-view approaching or exceeding 180 degrees. Because of their low part count, the systems can be robust and have a very small form factor.

Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

Abstract: The present invention, which is used for continuous variable quantum key distribution (CVQKD) with asynchronous local oscillators, relates to a system for performing a phase compensation of a scheme of using LO phase estimation and feedback at a receiver (Bob) using a pilot signal from a transmitter (Alice) and a scheme of measuring quantum state data using an LO having a predetermined phase at the receiver (Bob) and estimating and feeding back an LO phase through multi-dimensional reconciliation (MDR).

Abstract: A microfluidic pumping system configured to prevent backflow from an outlet of the system toward an inlet of the system. The microfluidic pumping system comprising a gear housing that has an inlet and an outlet and that houses a drive gear, an idler gear and a drive shaft. The system further includes a front end plate that is coupled to a first surface of the gear housing and a rear end plate that is coupled to a second, different surface of the gear housing. Also coupled to the gear housing is a first and second Halbach magnet arrays that is disposed between the front end plate and the rear end plate. The first and second Halbach magnet arrays include one or more solenoids and the first Halbach magnet array is disposed proximate to the drive gear and the second Halbach magnet array is disposed proximate to the idler gear.

Abstract: A 3D printed core-shell filament comprises an elongated core radially surrounded by an outer shell with a barrier layer in between, where the elongated core comprises a ductile polymer and the outer shell comprises a stiff polymer having a Young's modulus higher than that of the ductile polymer. A lightweight lattice structure may comprise a plurality of the 3D printed core-shell filaments deposited in layers.

Abstract: System, methods, and other embodiments described herein relate to self-supervised training for monocular depth estimation. In one embodiment, a method includes filtering disfavored images from first training data to produce second training data that is a subsampled version of the first training data. The disfavored images correspond with anomaly maps within a set of depth maps. The first depth model is trained according to the first training data and generates the depth maps from the first training data after initially being trained with the first training data. The method includes training a second depth model according to a self-supervised training process using the second training data. The method includes providing the second depth model to infer distances from monocular images.

Abstract: The present disclosure provides a synthetic nanoparticle comprising a peptide nucleic acid (PNA) oligomer conjugated to a lipid, wherein the PNA oligomer noncovalently complexes with an immunomodulatory compound, thereby forming a nanoparticle. The nanoparticles are useful to elicit immune responses and can be used to treat a broad range of cancers and infectious diseases.

Abstract: A thin-film solar module with a substrate and a layer structure applied thereon. The layer structure has a rear electrode layer, a front electrode layer, and an absorber layer arranged between the rear electrode layer and the front electrode layer. The absorber layer has doping of a first conductor type, while the front electrode layer has doping of a second conductor type. Serially connected solar cells are formed in the layer structure by patterning zones having a first patterning trench subdividing the rear electrode layer, a second patterning trench subdividing the absorber layer, and a third patterning trench subdividing the front electrode layer.

Abstract: The present invention is based, in part, on the identification of methods of modulating PD-1 expression and/or activity in regulatory T cells (Tregs) to thereby regulate effector immune responses in effector T cells (Teffs).

Abstract: The present invention improves the surface modification of NiTi alloys used for instance in medical devices through treatment with hydrogen particles in a suitable gaseous discharge and with oxygen atoms. The technique according to the present invention provides the formation of biocompatible solely titanium oxide layer thus preventing nickel to be present in the top surface layer. Furthermore this enables nanostructuring of the surface which depends on the treatment conditions. Devices made from NiTi alloys treated with the method according to the present invention have improved biocompatibility; platelets do not readily attach and activate on such surfaces and the thrombus formation rate is reduced in comparison with extensively used untreated NiTi alloys.

Abstract: A control method, system and device for a flexible carbon cantilever beam actuated by a smart material is provided. The new control method, system and device aims to solve the problems of control overflow and instability that are likely to occur in the distributed parameter system constructed in the prior art. The method includes: acquiring an elastic displacement of the flexible carbon cantilever beam in real time as input data; and obtaining, based on the input data, a control torque through a distributed parameter model constructed in advance, and performing vibration control on the flexible carbon cantilever beam. The new control method, system and device improves the control accuracy and stability of the distributed parameter system.

Abstract: The present disclosure relates, in some aspects, to bile acid sensors.

Abstract: A miniature quantitative optical coherence elastography system with an integrated Fabry-Perot force sensor for in situ elasticity measurement of biological tissue is provided. The technique has great potential for biomechanics modeling and clinical diagnosis. The qOCE system contains a fiber-optic probe that exerts a compressive force to deform tissue at the tip of the probe. Using the space-division multiplexed optical coherence tomography signal detected by a spectral domain optical coherence tomography engine, probe deformation in proportion to the force applied is quantified, as well as the tissue deformation corresponding to the external stimulus. Simultaneous measurement of force and displacement allows for calculation of Young's modulus from the biological tissue.

Abstract: A method of processing plaques in magnetic resonance imaging of vessel wall include: step S101, training a generative adversarial network and a capsule neural network to obtain a trained generator network and a trained capsule neural network; and step S102, cascade-connecting the trained generator network with the capsule neural network into a system to recognize and classify plaques in magnetic resonance imaging of vessel wall. In one aspect, the capsule neural network has more abundant vascular plaques characteristic information represented by vector; in another aspect, when the trained generator network and the capsule neural network are cascaded into the system to recognize and classify the plaques in magnetic resonance imaging of vessel wall, an accuracy of recognition and classification may be greatly improved. A device for processing the method as well as a computer for implementing are also disclosed.

Abstract: The present disclosure relates to a method for manufacturing a coin-type secondary battery. The method includes at least: bonding one or more solid electrolytes to an anode upper case; forming an anode active material layer on an anode current collector; sequentially stacking the anode current collector on which the anode active material layer is formed and the anode upper case to which the one or more solid electrolytes are bonded on an anode bottom case to obtain an anode part; sequentially stacking the anode part, a separator, a cathode current collector, and a second case including one or more openings on a first case; bonding the first case to the second case; and introducing an ion-containing solution containing sodium, lithium, magnesium, and a combination thereof from the outside of the second case into an interior thereof.

Abstract: A data optimization method and an integral prestack depth migration method are provided, including acquiring a target matrix to be optimized; generating a first sequence according to the target matrix; rarefying the first sequence according to a preset grid density to obtain a value position of each element of a second sequence, and working out a value of each element of the second sequence on the basis of the principle of least squares; performing interpolation on the second sequence to obtain a third sequence; calculating a target matrix corresponding to the third sequence; calculating an error between the target matrix to be optimized and the target matrix corresponding to the third sequence; recording, when the error is less than the first error threshold, the target matrix corresponding to the above second sequence as an optimized target matrix of the target matrix to be optimized.

Abstract: Methods, systems, and apparatuses are disclosed for a tamper-resistant collection and retention a chemical sample. In one embodiment, the tamper-resistant system comprises a container operable to collect and retain a chemical sample, a tamper-resistant mechanism operable to disengage at a first chemical sample to allow for a collection of a chemical sample, wherein the tamper-resistant mechanism is operable to record one or more of: a date, a time, and a location, of the chemical sample during the collection of the chemical sample, and wherein the tamper-resistant mechanism is further operable to re-engage and lock after the collection of the chemical sample to resist subsequent chemical samples after the first chemical sampling.

Abstract: A needle steering system and apparatus provides active, semi-autonomous control of needle insertion paths while still enabling a clinician ultimate control over needle insertion. A method and system controls the needle path as the needle is inserted by precisely controlling the rotation of the needle as it continuously rotates during insertion. This enables underactuated 2 degree-of-freedom (DOF) control of the direction and the curvature of the needle from a single rotary actuator. Control of the rotary motion is therefore decoupled from the needle insertion. The rotary motion controls steering effort and direction, while the insertion controls needle depth or insertion speed. In one implementation, the proposed method does not require constant velocity insertion, interleaved insertion and rotation, or known insertion position or speed. The insertion may be provided by a robot or other automated method, may be a manual insertion, or may be a teleoperated insertion.

Abstract: An image sensor includes a substrate, thin lenses disposed on a first surface of the substrate and configured to concentrate lights incident on the first surface, and light-sensing cells disposed on a second surface of the substrate, the second surface facing the first surface, and the light-sensing cells being configured to sense lights passing through the thin lenses, and generate electrical signals based on the sensed lights. A first thin lens and second thin lens of the thin lenses are configured to concentrate a first light and a second light, respectively, of the incident lights onto the light-sensing cells, the first light having a different wavelength than the second light.