Abstract: The present disclosure provides a rotary motor, which includes: a clamping member having a gripping unit installed at an inner circumference of a rotor to grip the rotor during a predetermined time; and a driving member installed at the inner circumference of the rotor and having a rotation unit configured to make an elastic deformation to rotate by a predetermined angle and then return to an original state so that the rotor is rotated.

Abstract: EGCG-Zn2+ molecular complexes exhibit a significantly higher affinity than the EGCG molecule alone or Zn2+ molecule alone for binding to different SARS-CoV-2 molecular targets and show virtually complete antiviral suppressive activity (>99%) against this virus in experimental models of infection. EGCG-Zn2+ complexes have a lower toxicity than EGCG alone in transfected human cells. The combination of EGCG and Zn2+, significantly improved some key pharmacokinetic parameters of EGCG in humans. Thus, these complexes are usable as a new broad-spectrum method for chemoprophylaxis or treatment of viral diseases by using formulations containing a composition of EGCG and Zn2+ or EGCG-Zn2+ complexes in sufficient amount to reach a blood concentration with antiviral effect, minimizing human safety issues.

Abstract: Provided is a bio-signal detection and stimulation device. The bio-signal detection and stimulation device includes a flexible substrate, a stimulation part on the flexible substrate, and a detection electrode part on the flexible substrate. The stimulation part and the detection electrode part vertically overlap each other, the stimulation part includes an organic light emitting diode (OLED), the stimulation part emits an optical signal, and the detection electrode part detects a bio-signal.

Abstract: The embodiments disclosed herein utilize RNA targeting effectors to provide a robust CRISPR-based diagnostic for hemorrhagic fever virus applications. Embodiments disclosed herein can differentiate between hemorrhagic fever viruses that present with similar symptoms, as well as between strains of a hemorrhagic fever virus.

Abstract: The present invention provides a fluorescent diamond containing an MV center emitting fluorescence at a concentration of 1×1014/cm3 or higher, where M represents a metal or metalloid, and V represents a vacancy.

Abstract: Disclosed are a pulverized coal preprocessing method and a pulverized coal gasifying method. The pulverized coal preprocessing method comprises the following steps: (1) performing pore broadening on pulverized coal to obtain preprocessed pulverized coal; (2) loading alkali metal ions into the preprocessed pulverized coal under an ion exchange condition to obtain alkali metal loaded pulverized coal. The method further comprises loading a chrome complex into the alkali metal loaded pulverized coal obtained in described step (2). In gasification, the pulverized coal loaded with alkali metal potassium and chrome catalysts obtained by the method has the advantages of high sulphur removal rate, high carbon conversion rate, short gasifying reaction time and high methane production.

Abstract: The present invention provides compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are binders of bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits using the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain-containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception.

Abstract: Disclosed herein are an apparatus and method for evaluating a human motion using a mobile robot. The method may include identifying the exercise motion of a user by analyzing an image of the entire body of the user captured using a camera installed in the mobile robot, evaluating the pose of the user by comparing the standard pose of the identified exercise motion with images of the entire body of the user captured by the camera of the mobile robot from two or more target locations, and comprehensively evaluating the exercise motion of the user based on the pose evaluation information of the user from each of the two or more target locations.

Abstract: The present invention relates to a method for preparing a humic acid-containing synergistic carrier for accelerating urea conversion. The preparation method includes steps of, for example, preparing an extractant for humic acid, preparing a humic acid extract and preparing a humic acid-containing synergistic carrier. Combination of the humic acid-containing synergistic carrier with urea can accelerate urea conversion, and the residual urea rate will be reduced by 22.7%-29.1% than a commercially available urea. The present invention provides a new idea for improving the utilization rate of nitrogen fertilizer in soil with low urease activity. Compared with a commercially available urea, the urea containing the humic acid-containing synergistic carrier of the present invention can increase the rice yield and the utilization rate of nitrogen fertilizer by 9.7% and 8.3%, respectively.

Abstract: The present disclosure, at least in part, relates to an engineered RNA (e.g., microRNA and sgRNA), in the absence of an input signal, that is engineered to have a large enough energy gap between the formations of a first secondary structure, which is unrecognizable by an actuator, and a second secondary structure, which is recognizable by an actuator (e.g., Drosha and Cas protein).

Abstract: In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than ?10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.

Abstract: Provided herein are immunogenic polypeptides, compositions, and methods related to the development of CMV-specific prophylactic and/or therapeutic immunotherapy based on T cell epitopes (e.g., CMV epitopes) that are recognized by cytotoxic T cells (CTLs) and can be employed in the prevention and/or treatment of CMV infection, reactivation, and/or disease (e.g., CMV-associated end organ disease), especially in solid organ transplant recipients.

Abstract: LED therapy masks, and associated systems and methods, are generally described. In one example, a wearable system for skin treatment of a user includes a substrate and a plurality of pixels disposed on the substrate. In this example, each pixel in the plurality of pixels includes a stack of light emitting diodes (LEDs) including a first LED configured to emit first light at a first wavelength and a second LED configured to emit light at a second wavelength. In this example, each pixel also includes a first microneedle in optical communication with the first LED and configured to guide the first light into the skin of the user during use and a second microneedle in optical communication with the second LED and configured to guide the second light into the skin of the user during use.

Abstract: An eddy-current correction method and apparatus, a mobile terminal and a readable storage medium are provided. The method includes: step S1: reading gradient-recalled echo sequence by means of bipolarity, so as to acquire a multi-echo image; step S2: estimating a first-order term coefficient of an extra phase term introduced by an eddy-current in the acquired multi-echo image; step S3: removing the estimated first-order term coefficient, and estimating a zero-order term coefficient of the extra phase term introduced by the eddy-current in the collected multi-echo image; step S4: removing, according to the estimated first-order term coefficient and the zero-order term coefficient, an error of the extra phase term introduced by the eddy-current. The eddy-current correction method removes the phase error caused by the eddy-current in the acquired image, thereby ensuring the correctness of the subsequent water-fat separation algorithm result.

Abstract: There is disclosed patient derived xenograft (PDXs) cells/systems/models and/or derivatives, parental (unlabelled) and/or labelled, expressing a fluorescent protein or a luciferase, or a combination thereof; for evaluating therapies comprising nasopharyngeal carcinoma (EBV positive and/or EBV negative). In another embodiment, there is disclosed a method of evaluating the efficacy of an agent used to treat nasopharyngeal carcinoma (NPC) comprising: preparing a non-human model; whereby the non-human model carries cells from NPC xenograft; labelling the cells from the NPC xenograft with gfp-luc2 marker using a lentiviral vector system; and growing the cells in short term in vitro culture; including adaptation of said culture into multi-well plates for use in further screening and/or evaluation assays; wherein the NPC xenograft is PDX.

Abstract: Artificial expression constructs for selectively modulating gene expression in selected central nervous system cell types are described. The artificial expression constructs can be used to selectively express synthetic genes or modify gene expression in excitatory cortical neurons, such as primarily within cortical layers 2/3, 4, 5, and 6 and including those with extratelencephalic (ET) projections, intratelencephalic (IT) projections, and pyramidal tract (PT) projections, among others.

Abstract: The current disclosure provides a method to improve the performance of evaporators and condensers by maintaining the vapor velocities on the heat exchange surfaces within a desired range. This is accomplished by providing a constant or tapered narrow gap for vapor flow in the heat exchangers. The shear induced by the vapor over the heat exchanger improves the evaporator performance by disturbing the liquid film flowing over the heat transfer surface. In the condenser, the vapor shear helps to remove the condensate in the form of film and droplets, and also removes the non-condensable gases from the heat transfer surfaces as the vapor condenses out and increases the concentration of the non-condensable gases over the heat transfer surfaces. Parameters identified include minimum gap and the taper angle between the cover plate and heat transfer surface.

Abstract: The present disclosure relates to a rosmarinic acid derivative, rosmarinic acid-derived particles, and a composition containing same for treating an inflammatory disease. The use of the rosmarinic acid derivative and rosmarinic acid-derived particles of the present disclosure enables the utilization of rosmarinic acid, which has been restricted in the utilization thereof due to low water solubility and low bioavailability, for a medicinal purpose.

Abstract: Systems and methods for scenario marker infrastructure are disclosed. In one embodiment, a method comprises receiving driving scenario data, extracting simulated sensor data from the driving scenario data, extracting scenario markers from the driving scenario data, inputting the simulated sensor data into autonomous driving software, receiving driving instructions output by the driving software, updating a driving status of the autonomous vehicle based on the driving instructions output by the autonomous driving software, creating a simulation log comprising the simulated sensor data and the driving instructions, and inserting the scenario markers into the simulation log.

Abstract: A method for scene reconstruction includes generating a depth estimate and a first pose estimate from a current image. The method also includes generating a second pose estimate based on the current image and one or more previous images in a sequence of images. The method further includes generating a warped image by warping each pixel in the current image based on the depth estimate, the first pose estimate, and the second pose estimate. The method still further includes controlling an action of an agent based on the second warped image.