Patents Assigned to INSTITUTE
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Patent number: 11169155Abstract: In some embodiments, a mass spectrometry tag may comprise a linker region, a mass balance region, and a reporter region. The mass spectrometry tag may be configured to fragment in a mass spectrometer via an energy dependent process to produce multiple reporter molecules. For example, the reporter region of the tag may be configured to produce at least two reporter molecules via fragmentation. In some embodiments, one or more regions of the tag may comprise at least one heavy isotope. In some such embodiments, the ability to fragment into multiple reporter molecules as well as the placement and/or number of heavy isotope(s) allows the mass spectrometry tag to be distinguished from other similar mass spectrometry tags. In some such embodiments, the ability to distinguish between tags having the same or substantially similar total mass to charge ratio and reporter region mass may allow the system to have a greater multiplexing capacity than conventional systems.Type: GrantFiled: June 3, 2016Date of Patent: November 9, 2021Assignees: President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.Inventors: Craig Braun, Wilhelm Haas, Steven P. Gygi, Gregory H. Bird, Loren D. Walensky, Martin Helmut Wuhr, Brian K. Erickson
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Patent number: 11168990Abstract: A map object management system including object information for objects in the environment around a location. The objects generally relating to the roadway on which a user is travelling. The map object management system provides a user with queries regarding detected objects that fail to meet confidence thresholds regarding the identification of the object. The map object management system receives answers to the queries to crowdsource uncertain or inaccurate object identifications for use in a map service to provide accurate map information to users.Type: GrantFiled: March 11, 2019Date of Patent: November 9, 2021Assignee: Toyota Research Institute, Inc.Inventors: Paul J. Ozog, Ryan W. Wolcott
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Patent number: 11171736Abstract: A radio frequency (RF) jamming device includes a differential segmented aperture (DSA), a jammer source outputting a jamming signal at one or more frequencies or frequency bands to be jammed, and RF electronics that amplify and feed the jamming signal to the DSA so as to emit a jamming beam. The DSA includes an array of electrically conductive tapered projections, and the RF electronics comprise power splitters configured to split the jamming signal to aperture pixels of the DSA. The aperture pixels comprise pairs of electrically conductive tapered projections of the array of electrically conductive tapered projections. The RF electronics further comprise pixel power amplifiers, each connected to amplify the jamming signal fed to a single corresponding aperture pixel of the DSA. The RF jamming device may include a rifle-shaped housing, with the DSA mounted at a distal end of the barrel of the rifle-shaped housing.Type: GrantFiled: May 22, 2020Date of Patent: November 9, 2021Assignee: BATTELLE MEMORIAL INSTITUTEInventor: Raphael Joseph Welsh
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Patent number: 11168276Abstract: Compositions and processes are disclosed for forming hydrophobic coatings and lubricant-infused surface coatings. Coatings may be applied to various substrates without prior chemical or temperature treatment of the substrates and over large and irregular surfaces. Coatings are self-healing, antifouling, and have enhanced lifetimes.Type: GrantFiled: December 1, 2017Date of Patent: November 9, 2021Assignee: Battelle Memorial InstituteInventors: Curtis J. Larimer, Raymond S. Addleman
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Patent number: 11172448Abstract: An operation method of a communication node for supporting a low power mode in a wireless LAN is disclosed. A method for operating an access point comprises: a step of transmitting a CTS frame to protect transmission of a wake-up packet, a step of transmitting the wake-up packet to wake up a station including PCR and WURx; and a step of transmitting a data frame to the station. Therefore, the performance of the communication system can be improved.Type: GrantFiled: May 8, 2018Date of Patent: November 9, 2021Assignee: Electronics and Telecommunications Research InstituteInventors: Sung Hyun Hwang, Seung Keun Park, Yong Ho Kim
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Patent number: 11168449Abstract: A method of batch-casting high-fluidity high performance concrete and low-fluidity high performance concrete, wherein the method is capable of batch-casting high-fluidity high performance concrete for forming a girder portion of a bridge and low-fluidity high performance concrete for forming a deck plate portion of the bridge by using a concrete casting apparatus. Accordingly, the construction cost can be reduced and the construction period can be shortened. In addition, because a cold joint does not occur, durability can be improved, and thus the life of the bridge can be increased.Type: GrantFiled: December 11, 2017Date of Patent: November 9, 2021Assignee: KOREA INSTITUTE OF CIVIL ENGINEERING AND BUILDING TECHNOLOGYInventors: Kyung Taek Koh, Gum Sung Ryu, Gi Hong An, Byung Suk Kim, Sung Yong Park
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Patent number: 11169104Abstract: A system for simulating the effects of use and aging on immersive coolants. Two conductive coils are immersed in a tank containing a sample of the coolant. The coils are spaced such that electrical activation of the first coil induces current in the second coil. A DC power source is provided to an inverter, which provides AC current for activating the first coil. The induced AC current in the second coil is delivered to a rectifier which converts the induced AC current to DC current. The DC current is then returned to the power source. The electromagnetic field between the coils simulates motor operation, so that the coolant's physical and chemical characteristics can be tested for the effects of use and aging.Type: GrantFiled: January 17, 2020Date of Patent: November 9, 2021Assignee: Southwest Research InstituteInventor: Bapiraju Surampudi
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Patent number: 11167275Abstract: The present disclosure is directed to producing zeolite structures with GME topologies using organic structure directing agents (OSDAs) comprising a piperidinium cation, and the compositions and structures resulting from these methods. In some embodiments, the crystalline products have a molar ratio of a molar ratio of Si:Al that is greater than 3.5.Type: GrantFiled: January 8, 2018Date of Patent: November 9, 2021Assignee: California Institute of TechnologyInventors: Michiel J. Dusselier, Mark E. Davis
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Patent number: 11168006Abstract: The present invention is directed to a ligated metal-organic framework (MOF) for use in removing both anionic and cationic species from a liquid or liquid stream. The present invention also provides methods for placing the MOF on a substrate to form a MOF-containing product that can be used in the removal of certain species from a given fluid. The MOF may be a Zr-based MOF, such as NU-1000, for removal of certain anions, such as oxy-anions, or having an attached thiosulfonyl-thiol (—SO2—S—R2—SH, where R2 is an alkyl group) ligand for complexation with certain cationic species in addition to the anions. The substrate may be any substrate to which a given MOF may be attached, including inert polypropylene polymer resin beads, a macroscopic fabric such as a mesh material or mesh filter, and a molecular fabric.Type: GrantFiled: August 25, 2019Date of Patent: November 9, 2021Assignee: Electric Power Research Institute, Inc.Inventors: Paul L. Frattini, Keith Paul Fruzzetti
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Patent number: 11168295Abstract: Disclosed herein is a bioprinter that enables the in situ formation of architected planar biomaterials and tissues by translating a printer head along a deposition surface, such as skin wounds. In handheld configurations of of the instrument, cell-laden biopolymer solutions are perfused through a moving microfabricated printhead and deposited onto a stationary planar surface or a wound. The printer head may be translated via a drive mechanism. Different embodiments of the instrument are disclosed form vivo application in small animals, as well as for large animal and clinical application. A stationary embodiment of the instrument is well suited for the continuous formation and roll-to-roll processing of planar biomaterials and tissues.Type: GrantFiled: October 10, 2017Date of Patent: November 9, 2021Assignees: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO, SUNNYBROOK RESEARCH INSTITUTEInventors: Navid Hakimi, Richard Yihsiu Cheng, Mohammad Hadi Sotoudehfar, Qing Ba, Saeid Amini-Nik, Marc G. Jeschke, Axel Guenther
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Patent number: 11167015Abstract: The present invention provides novel uses and methods for T cell based immunotherapies. Specifically, the invention relates to novel ligands, targets and nucleic acids and vectors encoding said targets that are useful for modulating T cell responses.Type: GrantFiled: October 12, 2017Date of Patent: November 9, 2021Assignee: INSTITUTE FOR RESEARCH IN BIOMEDICINEInventors: Roger Geiger, Antonio Lanzavecchia, Federica Sallusto
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Publication number: 20210338680Abstract: The present invention provides methods for modulating opioid receptor mediated analgesic effect, e.g., promoting or enhancing analgesia in subjects in need of pain relief. Also provided in the invention are methods for ameliorating or suppressing withdrawal symptoms in subjects with chronic opioid use. These methods of the invention entail administering to the subjects in need of treatment a therapeutically effective amount of a GPR139 antagonist compound. The invention further provides methods for identifying novel compounds that can be useful for modulating opioid receptor mediated analgesic effect.Type: ApplicationFiled: October 15, 2019Publication date: November 4, 2021Applicant: The Scripps Research InstituteInventors: Kirill Martemyanov, Brock Grill
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Publication number: 20210344006Abstract: A lithium metal negative electrode and a lithium metal battery including the lithium metal negative electrode. The lithium metal negative electrode includes a protective layer present on at least one surface of the negative electrode for stabilizing between the lithium metal and the electrolyte. The protective layer includes a polymer of alpha lipoic acid (ALA) and sulfur molecule (S8), a depolymerized product of the polymer, an inorganic sulfide-based compound, and at least one of an inorganic nitride-based compound, or an inorganic nitrate-based compound.Type: ApplicationFiled: July 16, 2019Publication date: November 4, 2021Applicants: LG CHEM, LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Jong Keon YOON, Yunjung KIM, Hyunwoong YUN, Sunwoo HWANG, Hoejin HAH, Hee-Tak KIM, Youngil ROH
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Publication number: 20210341405Abstract: A sensor can include one or more of a semiconducting material, an oxidation catalyst, and an oxidation enhancer, the sensor being configured to detect an analyte, such as methane, a thiol, or both.Type: ApplicationFiled: April 29, 2021Publication date: November 4, 2021Applicant: Massachusetts Institute of TechnologyInventors: Timothy SWAGER, Mate BEZDEK, Richard LIU
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Publication number: 20210341453Abstract: Methods and systems for estimating a groundwater recharge based on a pixel scale are disclosed. In some embodiments, a method includes the following steps: (1) obtaining an original remote sensing dataset of a climate element in a study area and a pixel area of the study area; (2) calculating a total water resource yield in the study area by a water balance equation according to the original remote sensing dataset of the climate element and the pixel area of the study area; and (3) estimating the groundwater recharge in the study area according to the total water resource yield and the monthly runoff in the study area. The original remote sensing dataset of the climate element includes monthly precipitation per unit pixel area, monthly actual evapotranspiration per unit pixel area, monthly snowmelt per unit pixel area, monthly soil moisture change per unit pixel area, and monthly runoff.Type: ApplicationFiled: April 30, 2020Publication date: November 4, 2021Applicant: Institute of Geochemistry, Chinese Academy of SciencesInventors: Xiaoyong BAI, Shijie WANG, Luhua WU, Fei CHEN, Miao ZHOU, Yichao TIAN, Guangjie LUO, Qin LI, Jinfeng WANG, Yuanhuan XIE, Yujie Yang, Chaojun LI, Yuanhong DENG, Zeyin HU, Shiqi TIAN, Qian LU, Chen RAN, Min LIU
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Publication number: 20210342031Abstract: A device and a method for generating floating images are provided. An optical imaging module generates a first floating image. A sensing module sends a detection signal to sense first position information of a tested object at a first time point, and generates a feedback signal according to the first position information when the first position information is within a contour range of the first floating image. A signal processing module is electrically connected to the optical imaging module and the sensing module to receive the feedback signal and generate at least one control command and/or at least one feedback command corresponding to the feedback signal. The at least one control command is transmitted to a controller to perform corresponding control on the controller, and the at least one feedback command is transmitted to the optical imaging module, so that the optical imaging module generates a second floating image different from the first floating image.Type: ApplicationFiled: April 21, 2021Publication date: November 4, 2021Applicant: Industrial Technology Research InstituteInventors: Yi-Hsiang Huang, Ping-Chang Jui, Hung Tsou, Szu-Wei Wu, Han-Sung Chan
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Publication number: 20210344916Abstract: Disclosed according to one exemplary embodiment includes not limited to: a filtering unit configured to generate filtering information by filtering a residual image corresponding to a difference between an original image and a prediction image; an inverse filtering unit configured to generate inverse filtering information by inversely filtering the filtering information; an estimator configured to generate the prediction image based on the original image and reconstruction information; a CNN-based in-loop filter configured to receive the inverse filtering information and the prediction image and to output the reconstruction information; and an encoder configured to perform encoding based on the filtering information and information of the prediction image, and wherein the CNN-based in-loop filter is trained for each of the plurality of artefact sections according to an artefact value or for each of the plurality of quantization parameter sections according to a quantization parameter.Type: ApplicationFiled: July 15, 2021Publication date: November 4, 2021Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGYInventor: Mun Churl KIM
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Publication number: 20210341283Abstract: The present disclosure relates to an apparatus and method for measuring the thickness and refractive index of a multilayer thin film by measuring angle-resolved spectral reflectance according to light polarization. According to an exemplary embodiment of the present disclosure, the apparatus and method for measuring the thickness and refractive index of a multilayer structure using angle-resolved spectroscopic reflectometry is capable of measuring and analyzing thickness and refractive index of each layer of a structure having a multilayer thin film through an s-polarized imaging and a p-polarized imaging of the reflective light located in a back focal plane of an objective lens which are acquired through an angle-resolved spectral imaging acquisition part.Type: ApplicationFiled: January 26, 2018Publication date: November 4, 2021Applicant: Korea Research Institute of Standards and ScienceInventors: Young-sik Ghim, Hyug-gyo Rhee
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Publication number: 20210340629Abstract: This invention relates generally to biomarkers that are useful for determining whether a subject with cancer is likely to respond to cancer therapy. The invention therefore relates to methods, kits and compositions for determining whether a subject is likely to respond to cancer therapy, and to methods of treatment based on a determination that a subject with cancer is likely to respond to cancer therapy. The invention also relates to methods for sensitizing a subject with cancer to cancer therapy.Type: ApplicationFiled: September 6, 2019Publication date: November 4, 2021Applicant: The Council of the Queensland Institute of Medical ResearchInventors: Jason Lee, Fares Al-Ejeh
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Publication number: 20210344115Abstract: The present invention relates to an integration module system of millimeter-wave and non-millimeter-wave antennas and an electronic apparatus, the system comprising a millimeter-wave antenna module and a non-millimeter-wave environment, the millimeter-wave antenna module forming a communication connection with the non-millimeter-wave environment for realizing reusing of the millimeter-wave antenna module to achieve a function of non-millimeter-wave antenna(s). The present invention proposes directly reusing a millimeter-wave antenna module, which is designed so that this module also has an antenna function of a non-millimeter-wave module, while an individual module's own volume does not need to be increased, and the module itself does not need to have additionally-added antenna traces, that is, with the same volume, a function of non-millimeter-wave antenna(s) may be further added.Type: ApplicationFiled: June 30, 2020Publication date: November 4, 2021Applicants: ETHETA COMMUNICATION TECHNOLOGY (SHENZHEN) CO.,LTD, EAST CHINA RESEARCH INSTITUTE OF MICROELECTRONICSInventors: Huan-Chu HUANG, Jiaguo LU, Hong LIN, Junyong LIU, Zhixing QI, Minhui ZENG, Yanchao ZHOU, Jingwei LI, Tao MA