Patents Assigned to INSTITUTE
  • Patent number: 11162886
    Abstract: Systems and methods for flowing particles, such as biological entities, in a fluidic channel(s) are generally provided. In some cases, the systems described herein are designed such that a single particle may be isolated from a plurality of particles and flowed into a fluidic channel (e.g., a microfluidic channel) and/or collected e.g., on fluidically isolated surfaces. For example, the single particle may be present in a plurality of particles of relatively high density and the single particle is flowed into a fluidic channel, such that it is separated from the plurality of particles. The particles may be spaced within a fluidic channel so that individual particles may be measured/observed over time. In certain embodiments, the particle may be a biological entity. Such article and methods may be useful, for example, for isolating single cells into individual wells of multi-well cell culture dishes (e.g., for single-cell analysis).
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: November 2, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert J. Kimmerling, Nicholas L. Calistri, Scott R. Manalis, Selim Olcum, Mark M. Stevens
  • Patent number: 11166040
    Abstract: An apparatus for decoding a video signal, the apparatus comprising a processor, wherein the processor is configured to: configure a Motion Vector Prediction (MVP) candidate list for motion compensation of a current block through one of a first method and a second method, acquire a motion vector predictor of the current block, based on the configured MVP candidate list, acquire a motion vector differential value indicating a difference between a motion vector of the current block and the motion vector predictor, modify the motion vector differential value, based on a resolution of the motion vector differential value of the current block, acquire the motion vector of the current block, based on the motion vector predictor and the modified motion vector differential value, and reconstruct the current block, based on the acquired motion vector.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: November 2, 2021
    Assignees: WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., HUMAX CO., LTD.
    Inventors: Geonjung Ko, Dongcheol Kim, Juhyung Son, Jaehong Jung, Jinsam Kwak
  • Patent number: 11164094
    Abstract: A device, method, and non-transitory computer readable storage medium for labelling motion data are provided. The device receives several motion signals, wherein each motion signal includes a motion time message and a motion data group. A motion script includes a plurality of preset motion messages, wherein each preset motion message includes a preset time message and a preset motion. The device performs the following steps for each preset time message: determining a first subset of the motion signals by comparing the motion time messages with the preset time message, calculating a similarity between the motion data group of each motion signal in the first subset and a reference model, determining a second subset of the first subset based on the first similarities, and labelling the motion data group of each motion signal included in the second subset as corresponding to the preset motion corresponding to the preset time message.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: November 2, 2021
    Assignee: INSTITUTE FOR INFORMATION INDUSTRY
    Inventors: Wei-Ming Chiang, Hsien-Cheng Liao
  • Patent number: 11161105
    Abstract: The present application relates to a hydrogenation catalyst, a process for producing the same and application thereof in the hydrotreatment of feedstock oil. The process comprises at least the following steps: (1) contacting a first active metal component and a first organic complexing agent with a carrier to obtain a composite carrier; (2) calcining the composite carrier to obtain a calcined composite carrier having a total carbon content of 1% by weight or less; and (3) contacting a second organic complexing agent with the calcined composite carrier to obtain the hydrogenation catalyst. The hydrogenation catalyst has both excellent hydrodesulfurization activity and hydrodenitrogenation activity, and exhibits a significantly prolonged service life.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: November 2, 2021
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC
    Inventors: Le Zhang, Mingfeng Li, Huifeng Li, Hong Nie, Shi Ding, Xuefen Liu, Zhihai Hu
  • Patent number: 11161859
    Abstract: The invention is directed to methods of converting a carboxylic acid group in a compound, via a redox active ester, to a corresponding boronic ester by treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(ll) salt or a copper salt, and an Mg(ll) salt, in the presence of an alkyllithium or a lithium hydroxide or alkoxide salt. The product pinacolato boronate ester can be cleaved to provide a boronic acid. The invention is also directed to methods of preparing various compounds of medical value comprising boronic acid groups, and to novel boronic-acid containing compounds of medicinal value, including an atorvastatin boronic acid analog, a vancomycin aglycone boronic acid analog, and boronic acid containing elastase inhibitors mCBK319, mCBK320, mCBK323, and RPX-7009.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: November 2, 2021
    Assignee: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Phil Baran, Chao Li, Jie Wang, Arnab Kumar Chatterjee, Manoj Kumar, Shan Yu, Kristen Ann Johnson, Tian Qin, Ming Shang
  • Patent number: 11162121
    Abstract: The present invention relates to a method for producing a medium chain diamine and, more specifically, to a method for producing a medium chain diamine from an alcohol or alkane derived from a fatty acid, by culturing a recombinant microorganism from which a fatty aldehyde dehydrogenase gene in a ?-oxidative metabolic pathway and a ?-oxidative metabolic pathway related gene have been deleted, and also into which a ?-transaminase gene has been introduced. The recombinant microorganism disclosed in the present invention can prevent the additional oxidation and ?-oxidation metabolism of fatty aldehyde and can produce a medium chain diamine with a high yield by introducing an amine group to the terminus thereof.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: November 2, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jung Oh Ahn, Hong Weon Lee, Gyu Yeon Park, Hee Suk Lee, Min Jeong Jang, Woo Young Jeon
  • Patent number: 11164312
    Abstract: A system associated with quantifying a density level of tumor-infiltrating lymphocytes, based on prediction of reconstructed TIL information associated with tumoral tissue image data during pathology analysis of the tissue image data is disclosed. The system receives digitized diagnostic and stained whole-slide image data related to tissue of a particular type of tumoral data. Defined are regions of interest that represents a portion of, or a full image of the whole-slide image data. The image data is encoded into segmented data portions based on convolutional autoencoding of objects associated with the collection of image data. The density of tumor-infiltrating lymphocytes is determined of bounded segmented data portions for respective classification of the regions of interest. A classification label is assigned to the regions of interest. It is determined whether an assigned classification label is above a pre-determined threshold probability value of lymphocyte infiltrated.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: November 2, 2021
    Assignees: The Research Foundation tor the State University of New York, Board of Regents, The University of Texas System, Institute for Systems Biology
    Inventors: Joel Haskin Saltz, Tahsin Kurc, Rajarsi Gupta, Tianhao Zhao, Rebecca Batiste, Le Hou, Vu Nguyen, Dimitrios Samaras, Arvind Rao, John Van Arnam, Pankaj Singh, Alexander Lazar, Ashish Sharma, Ilya Shmulevich, Vesteinn Thorsson
  • Patent number: 11160668
    Abstract: An implant including a first body member and a second body member and a first bone contacting element extending from the first body member to the second body member. The first bone contacting element may have a spiral configuration forming a plurality of arched members including at least two arched members extending substantially parallel to and offset with respect to one another.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: November 2, 2021
    Assignee: Institute for Musculoskeletal Science and Education, Ltd.
    Inventors: Joseph M. Nyahay, Edward J. McShane, III, Sean S. Bishop, Christopher J. Ryan, Megan A. Stauffer
  • Patent number: 11161860
    Abstract: The disclosure relates to the field of medicinal chemistry, in particular, to a class of small molecule compounds for inhibiting phosphodiesterase 4 (I), a preparation method thereof and a pharmaceutical composition comprising the compound. The pharmacodynamic test proves that the compound of the disclosure has the inhibitory activity of PDE-4 enzyme and the efficacy of inflammation treatment.
    Type: Grant
    Filed: December 25, 2018
    Date of Patent: November 2, 2021
    Assignees: HEFEI INDUSTRIAL PHARMACEUTICAL INSTITUTE CO., LTD, HEFEI AMVITE PHARMACEUTICAL CO., LTD.
    Inventors: Guangwei He, Zhaoxing Chu, Qinlong Xu, Feng Li, Weizhong Liu, Jiajia Mo, Yan Zhao
  • Patent number: 11162165
    Abstract: Disclosed herein is a nickel-based heat-resistant material with improved cyclic oxidation properties. The nickel-based heat-resistant material containing gadolinium (Gd) according to the present invention is capable of suppressing the de-lamination of an oxide layer and increasing stability of the oxide layer, thereby forming an overall thin and uniform oxide layer, and has an advantage in that the formation of a nitride may be suppressed since nitrogen is prevented from penetrating through the oxide layer. In addition, due to the slow oxidation rate, there is an advantage in that an Al depletion layer (a ?? denuded zone) by the formation of an oxide layer may be formed to be very thin compared to that of a specimen having no gadolinium added.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 2, 2021
    Assignee: KOREA INSTITUTE OF MATERIALS SCIENCE
    Inventors: Seong-Moon Seo, Dae Won Yun, Hi Won Jeong, Young Soo Yoo
  • Patent number: 11165958
    Abstract: Disclosed are methods and apparatuses for image data encoding/decoding. A method for decoding a 360-degree image includes the steps of: receiving a bitstream obtained by encoding a 360-degree image; generating a prediction image by making reference to syntax information obtained from the received bitstream; adding the generated prediction image to a residual image obtained by dequantizing and inverse-transforming the bitstream, so as to obtain a decoded image; and reconstructing the decoded image into a 360-degree image according to a projection format. Therefore, the performance of image data compression can be improved.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: November 2, 2021
    Assignee: B1 INSTITUTE OF IMAGE TECHNOLOGY, INC.
    Inventor: Ki Baek Kim
  • Patent number: 11164002
    Abstract: Disclosed herein are a method for human-machine interaction and an apparatus for the same. The method includes receiving object identification input for identifying an object related to the task to be dictated to a machine through the I/O interface of a user device that displays a 3D space; displaying an object identification visual interface, corresponding to the object identified within the space recognized by the machine, on the user device in an augmented-reality manner; receiving position identification input for identifying a position in the 3D space related to the task; displaying a position identification visual interface, corresponding to the position identified within the space recognized by the machine, on the user device in an augmented-reality manner; and receiving information related to the result of the task performed through the machine.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: November 2, 2021
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Joo-Haeng Lee
  • Patent number: 11161216
    Abstract: This disclosure relates to a belt grinder includes frame and first grinding assembly. The first grinding assembly includes transmission roller set, grinding belt and adjusting assembly. The transmission roller set includes driving roller and driven roller. Both the driving roller and the driven roller are rotatably disposed on the frame. The grinding belt is installed over the driving roller and the driven roller. The adjusting assembly includes rotatable component and contact rollers. The rotatable component is rotatably disposed on the frame. Rotation axis of the rotatable component is parallel to rotation axis of the driving roller. The contact rollers are rotatably disposed on the rotatable component. Contact rollers are different in shape. The rotatable component is rotatable with respect to the frame so as to force one of the contact rollers to contact or to be separated from the grinding belt.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: November 2, 2021
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsiang-Nien Chung, Hung-Hsiu Yu, Kuo-Feng Hung
  • Patent number: 11166004
    Abstract: The present disclosure proposes a three-dimensional computational imaging method and apparatus based on a single-pixel sensor, and a storage medium. The method includes the following. A stripe coding is combined with a two-dimensional imaging coding through a preset optical coding to generate a new optical coding, and the new optical coding is loaded into an spatial light modulator (SLM); a two-dimensional spatial information and depth information of a scene are coupled into a one-dimensional measurement value by using a single-pixel detector and the SLM loaded with the new optical coding; and the two-dimensional spatial information and the depth information of the scene are reconstructed, from the one-dimensional measurement value through a decoupling algorithm, for three-dimensional imaging.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: November 2, 2021
    Assignee: BEIJING INSTITUTE OF TECHNOLOGY
    Inventors: Liheng Bian, Jun Zhang, Xianbin Cao, Huayi Wang
  • Patent number: 11165221
    Abstract: Provided is an optical device including a radio frequency (RF) signal source configured to electrically provide an RF signal, a first diode configured to operate as a laser diode (LD) or an electro-absorption modulator (EAM) in response to the RF signal, a second diode configured to share an N region of the first diode, be serially connected to the first diode, and have a P region connected to a ground to operate as a capacitor for series push-pull operation with the first diode, and a resistor connected between the N region and the ground.
    Type: Grant
    Filed: August 5, 2019
    Date of Patent: November 2, 2021
    Assignee: Electronics and Telecommunications Research Institute
    Inventor: Shinmo An
  • Patent number: 11160492
    Abstract: A finger insert for use with a nailfold imaging device includes a housing to receive the user's finger and an immersion substance (e.g., immersion oil), and a deformable pad that holds the user's finger in place during imaging, as well as prevent bubble formation in the substance. The housing includes a transparent wall to facilitate imaging of the finger. The transparent wall includes multiple angled portions that prevent or reduce contact between the nailfold and the wall, to ensure sufficient blood flow through the nailfold region for imaging.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: November 2, 2021
    Assignee: Massachusetts Institute of Technology
    Inventor: Ian Butterworth
  • Patent number: 11161817
    Abstract: A quinoline derivative compound shown in formula (II), a pharmaceutically acceptable salt thereof, and an application of the same in preparing a drug for treating a disease related to a tyrosine kinase inhibitor.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: November 2, 2021
    Assignees: CHONGQING PHARMACEUTICAL INDUSTRIAL RESEARCH INSTITUTE CO. LTD., YAOPHARMA CO., LTD.
    Inventors: Yang Zhang, Zhengxia Chen, Meibi Dai, Wenju Li, Jian Li, Shuhui Chen
  • Patent number: 11162891
    Abstract: A device for measuring a reflectivity of an object at the seabottom, includes a spectral probe, a first white board, a second white board, a distance meter, and a shaft; the first white board and the second white board respectively have a known reflectivity; the first white board and the second white board are connected to the shaft, wherein the first white board and the second white board are spaced along an axial direction of the shaft and staggered from each other along a radial direction of the shaft; the spectral probe is configured to collect spectral data of the first white board, the second white board and the object at the seabottom; the distance meter is configured to collect distance data between the spectral probe and the object at the seabottom.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: November 2, 2021
    Assignee: SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Zhantang Xu, Jun Zhao, Yuezhong Yang, Cai Li, Wen Zhou, Kai Zeng, Wenxi Cao
  • Patent number: 11160862
    Abstract: The invention provides a nanoemulsion adjuvant and a preparation method thereof, which are composed of the following components: a continuous aqueous phase containing H2O molecules, an oil phase material containing fats and oils, and an emulsion system for stabilizing the interface between the continuous aqueous phase and the oil phase, and the emulsion system is an emulsifier mixture. The adjuvant is characterized in that the emulsion system does not contain an ionic emulsifier and the particle size of the emulsion is between 20 and 200 nanometers. The use of the nanoemulsion adjuvant can prevent toxicity and possible harm of ionic emulsifiers to human cells, and provide a vaccine preparation capable of eliciting a high degree of immune response.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: November 2, 2021
    Assignee: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Ming-Hsi Huang, Chung-Hsiung Huang, Chiung-Yi Huang
  • Patent number: PP33586
    Abstract: A new and distinct dragon fruit plant is described. The variety resulted from selection among a population of seedlings derived from a controlled cross carried out in 2013 between RF (seed parent) (not patented) and ‘LD5’ (pollen parent) (not patented) located in Tien Giang, Viet Nam. The variety was selected due to its appearance, eating quality and canker tolerance.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: November 2, 2021
    Assignees: The New Zealand Institute for Plant and Food Research Limited, Southern Horticultural Research Institute
    Inventors: Tran Thi Oanh Yen, Nguyen Nhat Truong, Thi Nguyen Ngoc, Huynh Van Chanh, Satish Kumar