Abstract: Described herein are methods of physicochemical-guided peptide design that utilize specific functional determinants to a protein's property of interest. Also described herein are novel synthetic peptide antibiotics that have increased potency and/or decreased toxicity relative to the template peptide from which they were derived, and methods of use thereof in treating microbial infections.

Abstract: A technology called RINSE (Removal of Incubated Nanotubes through Selective Exfoliation) is demonstrated. RINSE removes carbon nanotube (CNT) aggregates in CNFETs without compromising CNFET performance. In RINSE, CNTs are deposited on a substrate, coated with a thin adhesive layer, and sonicated. The adhesive layer is strong enough to keep the individual CNTs on the substrate, but not the larger CNT aggregates. When combined with a CNFET CMOS process as disclosed here, record CNFET CMOS yield and uniformity can be realized.

Abstract: Provided is a button device including a humidity sensor. The button device includes a substrate having a plurality of sensing regions, a housing on the substrate, the housing separating a first sensing region of the plurality of sensing regions from other sensing regions, a porous structure within the housing, the porous structure having through-holes, a first electrode on the porous structure, a second electrode on the porous structure, the second electrode being electrically connected to the first electrode through the porous structure, and a temperature sensor disposed adjacent to the first sensing region to sense a temperature of the first sensing region, The porous structure includes a body having an outer surface defining the through-holes, the body having an air gap therein.

Abstract: There is provided a method and apparatus of encoding/decoding an intra prediction mode. The method comprises deriving an intra prediction mode with respect to a current block, constructing a reference sample for the current block on the basis of the derived intra prediction mode, and performing the intra prediction with respect to the current block using the derived intra prediction mode and the constructed reference sample, wherein the intra prediction mode is derived on the basis of a most probable mode (MPM).

Abstract: Apparatus, systems, and methods for forming semiconductor materials (e.g., using nanofabrication) are generally described. In one example, a method comprises formation of a carbon buffer layer on a first substrate and a graphene layer on the carbon buffer layer by silicon sublimation, followed by removing the graphene layer so as to expose the carbon buffer layer and form a fabrication platform.

Abstract: Disclosed is a speech processing apparatus and method using a densely connected hybrid neural network. The speech processing method includes inputting a time domain sample of N*1 dimension for an input speech into a densely connected hybrid network; passing the time domain sample through a plurality of dense blocks in a densely connected hybrid network; reshaping the time domain samples into M subframes by passing the time domain samples through the plurality of dense blocks, inputting the M subframes into gated recurrent unit (GRU) components of N/M-dimension; outputting clean speech from which noise is removed from the input speech by passing the M subframes through GRU components.

Abstract: Systems and methods to improve machine learning by explicitly over-fitting environmental data obtained by an imaging system, such as a monocular camera are disclosed. The system includes training self-supervised depth and pose networks in monocular visual data collected from a certain area over multiple passes. Pose and depth networks may be trained by extracting data from multiple images of a single environment or trajectory, allowing the system to overfit the image data.

Abstract: Methods and pharmaceutical compositions comprising one or more mTOR inhibitors such as sirolimus and one or more receptor tyrosine kinase inhibitors such as nintedanib are disclosed for treating vascular lesions and hereditary hemorrhagic telangiectasia.

Abstract: An image decoding method is disclosed in the present specification. An image decoding method according to the present invention may comprise deriving a candidate list for inter-prediction of a current block, deriving motion information of the current block by using the candidate list, deriving a cumulative coding information candidate by using the motion information of the current block, inserting the derived cumulative coding information candidate into a cumulative coding information candidate list and updating the candidate list by using the cumulative coding information candidate list, wherein the updated candidate list is used for inter-prediction of a block to be decoded after the current block.

Abstract: A method of forming a copolymer includes reacting with to form a salt. x parts by mole of the salt with y parts by mole of are reacted to form the copolymer having a chemical structure as wherein m=4-10, n=4-6, and x:y=1:9 to 4:6. The copolymer may have a relative viscosity of 1.5 to 4.0.

Abstract: The present disclosure relates to a prelithiation solution and a method for preparing a prelithiated anode using the same. The prelithiation solution and the method for preparing a prelithiated anode using the same according to the present disclosure allow uniform intercalation of lithium ions throughout the anode chemically in a solution via a simple process of immersing the anode in a prelithiation solution having a sufficiently low redox potential as compared to an anode active material. A prelithiated anode prepared by this method has an ideal initial coulombic efficiency and a lithium secondary battery with a high energy density can be prepared based thereon. In addition, the prepared anode is advantageously applicable to large-scale production due to superior stability even in dry air.

Abstract: An image decoding method is disclosed in the present specification. An image decoding method according to the present invention may comprise determining a prediction mode of a current block and performing prediction with respect to the current block on the basis of the determined prediction mode.

Abstract: A method for removing ash from a solid carbon material: Reaction conditions are mild, and ash may be removed more effectively. The ash removing method comprises: S1) mixing an alkaline sub-molten salt medium and a solid carbonaceous material to be treated, heating so that alkali and ash in the solid carbonaceous material to be treated react in the alkaline sub-molten salt medium, and performing solid-liquid separation on a mixed slurry resulting from the reaction to obtain a first solid product and an alkali treatment solution, wherein in the alkaline sub-molten salt medium, the mass fraction of the alkali is greater than or equal to 50%; S2) using an acid solution to perform acid cleaning treatment on the first solid product, and performing solid-liquid separation again to obtain a second solid product and an acid cleaning solution.

Abstract: Disclosed is a method for defining the stages of development of a cyanobacterial bloom, wherein the development of a cyanobacterial bloom is divided into five stages: a cyanobacteria wintering period, a resuscitation period, a rapid growth period, an outbreak period and a cyanobacteria decline period; the wintering period is defined based on the concentration/content ratio of algocyan/chlorophyll a; the resuscitation period is defined based on the relative expression levels of the phycocyanin synthesis gene PC-IGS, the algal toxin synthesis gene mcyA and the gas vesicle synthesis gene gvpC in the surface sediment; the cyanobacteria rapid growth period is defined based on the relative expression level of the ftsZ gene; the cyanobacteria outbreak period is defined based on the wind speed; and the cyanobacteria decline period is defined based on the relative expression level of the nblA gene and the ratio of glucose to neutral polysaccharides in dissolved organic matter.

Abstract: Methods include directing a group of ions through a separation region of an ion manipulation apparatus, separating the group of ions in the separation region based on ion mobility, selecting a subset of the group of ions based on a dependence between ion mobility and ion arrival time of the separated ions at a deposition switch of the ion manipulation apparatus, and depositing the selected subset of ions on a substrate. Related systems and ion manipulation apparatus are disclosed. Also disclosed are methods and system that provide concurrent ion accumulation and ion separation in coupled and switchable electrode regions using traveling wave electric fields.

Abstract: A hydrogen fueling control device and method comprising step S100, obtaining initial parameters of a vehicle-mounted hydrogen reservoir, wherein the initial parameters comprise volume, initial hydrogen pressure, and initial ambient temperature of the vehicle-mounted hydrogen reservoir; step S200, computing a fueling rate and a target pressure for hydrogen fueling according to the initial parameters, wherein the computed fueling rate and target pressure cause the temperature of hydrogen during a hydrogen fueling process to be within a preset safe range; and step S300, controlling a hydrogen fueling station to fuel hydrogen to the vehicle-mounted hydrogen reservoir at the computed fueling rate to the computed target pressure.

Abstract: A method is presented. The method includes estimating an ego-motion of an agent based on a current image from a sequence of images and at least one previous image from the sequence of images. Each image in the sequence of images may be a two-dimensional (2D) image. The method also includes estimating a depth of the current image based the at least one previous image. The estimated depth accounts for a depth uncertainty measurement in the current image and the at least one previous image. The method further includes generating a three-dimensional (3D) reconstruction of the current image based on the estimated ego-motion and the estimated depth. The method still further includes controlling an action of the agent based on the three-dimensional reconstruction.

Abstract: Disclosed embodiments relate to a convolutional neural network computing method and system based on weight kneading, comprising: arranging original weights in a computation sequence and aligning by bit to obtain a weight matrix, removing slack bits in the weight matrix, allowing essential bits in each column of the weight matrix to fill the vacancies according to the computation sequence to obtain an intermediate matrix, removing null rows in the intermediate matrix, obtain a kneading matrix, wherein each row of the kneading matrix serves as a kneading weight; obtaining positional information of the activation corresponding to each bit of the kneading weight; divides the kneading weight by bit into multiple weight segments, processing summation of the weight segments and the corresponding activations according to the positional information, and sending a processing result to an adder tree to obtain an output feature map by means of executing shift-and-add on the processing result.

Abstract: Provided herein are compositions, methods of making, and methods of use relating to reversibly compressible tissue-hydrogel hybrids.

Abstract: Disclosed is a kinase inhibitor, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, ester, acid, metabolite, or prodrug thereof. Also disclosed are a pharmaceutical composition comprising the kinase inhibitor and uses and methods for inhibiting the activity of one or more tyrosine kinases selected from MST1 and a mutant thereof in a cell or subject and for preventing or treating a disease related to MST1 or a mutant thereof in a subject by using the compound or composition.