Abstract: In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.
Type:
Grant
Filed:
November 17, 2017
Date of Patent:
August 31, 2021
Assignees:
Japan, as represented by the Director-General of National Institute of Infectious Disease, ID Pharma Co., Ltd.
Inventors:
Tetsuro Matano, Makoto Inoue, Hiroto Hara, Tsugumine Shu
Abstract: Techniques to manage virtual classes for statistical tests are described. An apparatus may comprise a simulated data component to generate simulated data for a statistical test, statistics of the statistical test based on parameter vectors to follow a probability distribution, a statistic simulator component to simulate statistics for the parameter vectors from the simulated data with a distributed computing system comprising multiple nodes each having one or more processors capable of executing multiple threads, the simulation to occur by distribution of portions of the simulated data across the multiple nodes of the distributed computing system, and a distributed control engine to control task execution on the distributed portions of the simulated data on each node of the distributed computing system with a virtual software class arranged to coordinate task and sub-task operations across the nodes of the distributed computing system. Other embodiments are described and claimed.
Abstract: The present invention relates to a method for generating a filter for an audio signal and a parameterization device for the same, and more particularly, to a method for generating a filter for an audio signal, to implement filtering of an input audio signal with a low computational complexity, and a parameterization device therefor.
Type:
Grant
Filed:
April 30, 2020
Date of Patent:
August 31, 2021
Assignees:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC., GCOA CO., LTD.
Abstract: Methods described herein provide a way to reduce or eliminate drag and adhesion of a substance flowing over a surface by creating a vapor cushion via evaporation of a phase-changing material of or on the surface or encapsulated within textures of the surface. The vapor cushion causes the flowing substance to be suspended over the surface, greatly reducing friction, drag, and adhesion between the flowing substance and the surface. The temperature of the flowing substance is above the sublimation point and/or melting point of the phase-changing material. The phase-changing material undergoes a phase change (evaporation or sublimation) upon contact with the flowing substance due to local heat transfer from the flowing substance to the material, generating a vapor cushion between the solid or liquid material and the flowing substance.
Abstract: Message routing techniques include use of at least one controller module configured to maintain a graph. The graph defines communication relations between a plurality of message communication modules. Each communication relation defines a particular message type for a particular pair of modules. The plurality of message communication modules includes a first module configured to receive a message wherein the received message has a message type and is associated with least one pre-condition. Upon verification of an acceptance condition of the at least one pre-condition the received message is accepted if the acceptance condition is fulfilled. Upon verification of a generating condition of the at least one pre-condition, the first module generates a generated message directed to at least a second module or an external data consumer in accordance with the graph if the generating condition is fulfilled.
Abstract: An oxide sintered body having metal elements composed of In, Ga, Zn and Sn and containing a hexagonal layered compound represented by InGaO3(ZnO)m (m is an integer of 1 to 6). When ratios (atomic %) of contents of In, Zn and Sn to all metal elements excluding oxygen contained in the oxide sintered body are taken as [In], [Zn] and [Sn], respectively, the relations [Zn]?40 atomic %, [In]?15 atomic %, [Sn]?4 atomic % are satisfied.
Abstract: Disclosed are a learning data generation method and apparatus needed to learn animation characters on the basis of deep learning. The learning data generation method needed to learn animation characters on the basis of deep learning may include collecting various images from an external source using wired/wireless communication, acquiring character images from the collected images using a character detection module, clustering the acquired character images, selecting learning data from among the clustered images, and inputting the selected learning data to an artificial neural network for character recognition.
Type:
Grant
Filed:
November 26, 2019
Date of Patent:
August 31, 2021
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Dong Hyuck Im, Jung Hyun Kim, Hye Mi Kim, Jee Hyun Park, Yong Seok Seo, Won Young Yoo
Abstract: A solid electrolyte material is of the formula A7±2xP3X((11±x)?y)Oy wherein wherein A is Li or Na, wherein X is S, Se, or a combination thereof, provided that when M is Li, X is Se, and wherein 0?x?0.25 and 0?y?2.5. Also, an electrochemical cell including the solid electrolyte material, and methods for the manufacture of the solid electrolyte material and the electrochemical cell.
Type:
Grant
Filed:
April 30, 2018
Date of Patent:
August 31, 2021
Assignees:
SAMSUNG ELECTRONICS CO., LTD, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Inventors:
Yan Wang, Lincoln Miara, Gerbrand Ceder, William D. Richards
Abstract: Embodiments relate to a dual Brillouin distributed optical fiber sensing system and a sensing method using Brillouin scattering that detects an event area in which an event occurred quickly by simultaneously measuring multiple correlation points located in an optical fiber under test by using a pump signal modulated with a pulsed gating signal and a continuous wave probe signal, and then precisely measures the corresponding event area by using the probe signal modulated with the pulsed gating signal and the pump signal.
Type:
Grant
Filed:
November 19, 2019
Date of Patent:
August 31, 2021
Assignee:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Kwan Il Lee, Gukbeen Ryu, Sang Bae Lee, In Soo Kim, Wonsuk Lee
Abstract: Stimulated Brillouin scattering (SBS) limits the maximum power in fiber lasers with narrow linewidths. SBS occurs when the power exceeds a threshold proportional to the beam area divided by the effective fiber length. The fiber lasers disclosed here operate with higher SBS power thresholds (and hence higher maximum powers at kilohertz-class linewidths) than other fiber lasers thanks to several techniques. These techniques include using high-absorption gain fibers, operating the laser with low pump absorption (e.g., ?80%), reducing the length of un-pumped gain fiber at the fiber output, foregoing a delivery fiber at the output, foregoing a cladding light stripper at the output, using free-space dichroic mirrors to separate signal light from unabsorbed pump light, and using cascaded gain fibers with non-overlapping Stokes shifts. The upstream gain fiber has high absorption and a larger diameter for high gain, and subsequent gain fiber has a smaller diameter to improve beam quality.
Type:
Grant
Filed:
May 1, 2020
Date of Patent:
August 31, 2021
Assignee:
Massachusetts Institute of Technology
Inventors:
Steven J. Augst, Kelsey Yee, Franklin Jose
Abstract: According to an embodiment of the present invention, there is provided an image decoding method including: obtaining an arithmetic-coded symbol stream from an image stream; identifying a symbol segment from the symbol stream according to symbol segment information signaled from an encoding apparatus; selecting an arithmetic decoding process corresponding to the symbol segment; and collectively processing one or more symbols among multiple symbols included in the symbol segment, in association with the selected arithmetic decoding process.
Type:
Grant
Filed:
February 27, 2018
Date of Patent:
August 31, 2021
Assignees:
Electronics and Telecommunications Research Institute, CHIPS & MEDIA, INC.
Inventors:
Dae Yeon Kim, Sung Chang Lim, Jung Won Kang, Ha Hyun Lee, Jin Ho Lee, Hui Yong Kim
Abstract: Methods are described for predicting ancestral sequences for viruses or portions thereof. Also described are predicted ancestral sequences for adeno-associated virus (AAV) capsid polypeptides. The disclosure also provides methods of gene transfer and methods of vaccinating subjects by administering a target antigen operably linked to the AAV capsid polypeptides.
Type:
Grant
Filed:
December 17, 2019
Date of Patent:
August 31, 2021
Assignees:
The Schepens Eye Research Institute, Inc., Massachusetts Eye and Ear Infirmary
Abstract: In one embodiment, a method for collecting lane data is disclosed. The method includes collecting lane data, for a lane of a plurality of lanes of a road, from one or more sensors of a vehicle traveling in the lane. The method includes receiving an identifier of a lane of the plurality of lanes. The identified lane is a lane-of-interest and is different from the lane that the vehicle is traveling in. The method includes determining that the vehicle is not occupied. The method includes causing, in response to determining that the vehicle is not occupied, the vehicle to travel in the lane-of-interest. The method includes collecting lane data, for the lane-of-interest from the one or more sensors.
Abstract: Provided is a radar device including a clock generator, a transmitter, and a receiver. The clock generator may output a transmission clock, and output a reception clock after a delay from a time at which the transmission clock is output. The transmitter may include a transmission trigger signal generator to generate a transmission trigger signal based on the transmission clock and an oscillator configured to generate a first signal on the basis of the transmission trigger signal. The first signal and the transmission trigger signal may include a pulse, and a width and a magnitude of the pulse included in the first signal correspond to a width and a magnitude of the pulse included in the transmission trigger signal, respectively. The receiver may be configured to receive an echo signal corresponding to the first signal to generate a second signal based on the reception clock.
Type:
Grant
Filed:
November 19, 2018
Date of Patent:
August 31, 2021
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Disclosed is an asymmetrical half-bridge converter having high efficiency in a wide input voltage range. The converter may include a primary-side circuit including a first switch, a second switch, a primary-side capacitor, an additional inductor, and a primary-side magnetization inductor, and a secondary-side circuit including first and second diodes connected in series, first and second capacitors connected in series, a secondary-side rectification inductor having one end connected to the anode of the first diode and cathode of the second diode, and having the other end connected between the first and second capacitors connected in series, a first coupling inductor having one end connected to the cathode of the first diode and having the other end connected to the first capacitor, and a second coupling inductor having one end connected to the anode of the second diode and having the other end connected to the second capacitor.
Type:
Grant
Filed:
January 2, 2020
Date of Patent:
August 31, 2021
Assignee:
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Gun-Woo Moon, Jung-Kyu Han, Seung-Hyun Choi, Jong-Woo Kim, Keon-Woo Kim, Cheon-Yong Lim
Abstract: In some embodiments, a mass spectrometry tag may comprise a linker region, a mass balance region, and a reporter region. The mass spectrometry tag may be configured to fragment in a mass spectrometer via an energy dependent process to produce multiple reporter molecules. For example, the reporter region of the tag may be configured to produce at least two reporter molecules via fragmentation. In some embodiments, one or more regions of the tag may comprise at least one heavy isotope. In some such embodiments, the ability to fragment into multiple reporter molecules as well as the placement and/or number of heavy isotope(s) allows the mass spectrometry tag to be distinguished from other similar mass spectrometry tags. In some such embodiments, the ability to distinguish between tags having the same or substantially similar total mass to charge ratio and reporter region mass may allow the system to have a greater multiplexing capacity than conventional systems.
Type:
Grant
Filed:
November 22, 2019
Date of Patent:
August 31, 2021
Assignees:
President and Fellows of Harvard College, Dana-Farber Cancer Institute, Inc.
Inventors:
Craig Braun, Wilhelm Haas, Steven P. Gygi, Gregory H. Bird, Loren D. Walensky, Martin Helmut Wuhr, Brian K. Erickson
Abstract: A bit interleaver, a bit-interleaved coded modulation (BICM) device and a bit interleaving method are disclosed herein. The bit interleaver includes a first memory, a processor, and a second memory. The first memory stores a low-density parity check (LDPC) codeword having a length of 16200 and a code rate of 4/15. The processor generates an interleaved codeword by interleaving the LDPC codeword on a bit group basis. The size of the bit group corresponds to a parallel factor of the LDPC codeword. The second memory provides the interleaved codeword to a modulator for 64-symbol mapping.
Type:
Grant
Filed:
July 19, 2019
Date of Patent:
August 31, 2021
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung-Ik Park, Sun-Hyoung Kwon, Bo-Mi Lim, Jae-Young Lee, Heung-Mook Kim, Nam-Ho Hur
Abstract: A neural network-based error compensation method for 3D printing includes: compensating an input model by a deformation network/inverse deformation network constructed and trained according to a 3D printing deformation function/inverse deformation function, and performing the 3D printing based on the compensated model. Training samples of the deformation network/inverse deformation network include to-be-printed model samples and printed model samples. The deformation network constructed according to the 3D printing deformation function is marked as a first network. During training of the first network, the to-be-printed model samples are used as real input models, and the printed model samples are used as real output models. The inverse deformation network constructed according to the 3D printing inverse deformation function is marked as a second network.
Type:
Grant
Filed:
September 16, 2019
Date of Patent:
August 31, 2021
Assignees:
INSTITUTE OF AUTOMATION, CHINESE ACADEMY OF SCIENCES, BEIJING TEN DIMENSIONS TECHNOLOGY CO., LTD.
Inventors:
Zhen Shen, Gang Xiong, Yuqing Li, Hang Gao, Yi Xie, Meihua Zhao, Chao Guo, Xiuqin Shang, Xisong Dong, Zhengpeng Wu, Li Wan, Feiyue Wang
Abstract: Cancer is a complex group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Described herein are compositions and methods for the treatment of cancer.
Type:
Grant
Filed:
December 19, 2018
Date of Patent:
August 31, 2021
Assignee:
THE PACIFIC HEART, LUNG, & BLOOD INSTITUTE
Abstract: System, methods, and other embodiments described herein relate to generating depth estimates from a monocular image. In one embodiment, a method includes, in response to receiving the monocular image, flipping, by a disparity model, the monocular image to generate a flipped image. The disparity model is a machine learning algorithm. The method includes analyzing, using the disparity model, the monocular image and the flipped image to generate disparity maps including a monocular disparity map corresponding to the monocular image and a flipped disparity map corresponding with the flipped image. The method includes generating, in the disparity model, a fused disparity map from the monocular disparity map and the flipped disparity map. The method includes providing the fused disparity map as the depth estimates of objects represented in the monocular image.
Type:
Grant
Filed:
February 15, 2019
Date of Patent:
August 31, 2021
Assignee:
Toyota Research Institute, Inc.
Inventors:
Sudeep Pillai, Rares A. Ambrus, Adrien David Gaidon