Abstract: A method and apparatus for processing an audio signal are disclosed. According to an example embodiment, a method of processing an audio signal may include acquiring a final audio signal for an initial audio signal using a plurality of neural network models generating output audio signals by encoding and decoding input audio signals, calculating a difference between the initial audio signal and the final audio signal in a time domain, converting the initial audio signal and the final audio signal into Mel-spectra, calculating a difference between the Mel-spectra of the initial audio signal and the final audio signal in a frequency domain, training the plurality of neural network models based on results calculated in the time domain and the frequency domain, and generating a new final audio signal distinguished from the final audio signal from the initial audio signal using the trained neural network models.

Abstract: An analysis device includes a parameter sample data calculation unit that calculates a plurality of pieces of sample data for parameters for a simulator, based on a temporarily set distribution for the parameters, the simulator receiving inputs of data of a first type and outputting data of a second type; a second type sample data acquisition unit that inputs, to the simulator, target data of the first type indicating a target value for the data of the first type and sample data for the parameters and obtains sample data of the second type for each of the plurality of pieces of sample data for the parameters; and a parameter value calculation unit that calculates a weight for each of the plurality of pieces of sample data for the parameters based on the difference between target data of the second type indicating a target value for the data of the second type and the calculated sample data of the second type and based on the relationship between a first distribution followed by the target data of the first ty

Abstract: The present disclosure relates to compositions, methods, and kits for rapid phenotypic detection of antibiotic resistance/susceptibility.

Abstract: A multi-stage bubble-column vapor mixture condenser includes at least a first stage and a second stage. Each stage includes a condenser chamber including a carrier-gas inlet and a carrier-gas outlet and contains a condensing bath. Carrier gas bubbles from the carrier-gas inlet up through the condensing bath, overcoming a hydrostatic head of the condensing bath, to a volume of carrier gas above the condensing bath. The carrier-gas outlet is positioned with an opening for carrier-gas extraction, and the first-stage carrier-gas outlet is in fluid communication with the second-stage carrier-gas inlet to facilitate flow of the carrier gas through the condensing bath in the first-stage condenser chamber, into the volume of carrier gas above the first-stage condensing bath, and then through the condensing bath in the second-stage condenser chamber.

Abstract: The disclosure provides a non-therapeutic method for regulating DAT gene expression in a cell, which includes the step of increasing or decreasing an amount of a miR-132/212 in the cell; further provides a use of the above miRNA, an enhancer thereof or an attenuator thereof in preparing a drug for regulating uptake of dopamine by a cell; and an application of the above miRNA, the enhancer thereof or the attenuator thereof in preparing a drug for treating psychoactive substance addiction.

Abstract: A ruggedized adjustable mounting system is described for adjustably coupling and selectively locking a component supported in a fixture of the mount in a desired orientation. In some embodiments, the mounting system includes one or more kinematic couplings that support a fixture on a base and one or more adjustable couplings that are configured to adjust a separation distance between two opposing portions of the fixture and the base to selectively pivot the fixture about one or more axes of rotation.

Abstract: Provided are a display device and an augmented reality apparatus including the same. The display device includes a display panel including display blocks and an optics array including pin hole structures that one-to-one correspond to the display blocks. Here, each of the pin hole structures includes a pin hole and a shielding area surrounding the pin hole, and the display blocks are spaced apart from each other in a first direction parallel to a top surface of the display panel and a second direction crossing the first direction and parallel to the top surface of the display panel.

Abstract: Disclosed is an optical transmitter module including a directly modulated laser transmitter based on a directly modulated laser (DML) and an arrayed waveguide grating (AWG) chip that is vertically polished. The directly modulated laser transmitter includes a directly modulated laser chip array including one or more directly modulated laser chips, an impedance matching circuit that allows each of the one or more directly modulated laser chips to operate at a critical speed of 100 Gbps per channel or higher, and a radio frequency-flexible printed circuit board (RF-FPCB) that transmits a radio frequency (RF) modulating signal to the directly modulated laser chip array. The arrayed waveguide grating chip includes an optical waveguides that transfer multi-channel optical signals and a wavelength multiplexer that multiplexes the multi-channel optical signals. The directly modulated laser transmitter and the arrayed waveguide grating chip are spaced apart from each other and are optically coupled in chip-to-chip.

Abstract: Provided is a cold atomic beam generation technology that causes a cold atomic beam to travel in a direction different from the traveling direction of a pushing laser beam. The pushing laser beam is used to generate a cold atomic beam from atoms trapped in a space. Next, the cold atomic beam is deflected by using a zero magnetic field line of a quadrupole magnetic field in a two-dimensional magneto-optical trap mechanism or by using a drift direction of a standing light wave in a moving molasses mechanism.

Abstract: Lifting robot systems and methods for operating the same are disclosed. A lifting robot system includes a sensor device and a robot device. The robot device includes a body, a lifting component movably coupled to the body, and a collection tray coupled to the lifting component. Upon receiving a command to lift an object, the sensor device automatically detects the object, the robot device places the object on the collection tray, and the robot device causes the lifting component to lift the collection tray from a first height to a second height.

Abstract: Disclosed in one embodiment are a device for measuring water level by using a capacitive technique, and a method therefor. A device for measuring water level comprises: an electrode unit which includes a first electrode and a second electrode arranged in parallel in a lengthwise direction, and which allow voltages to be applied to the first electrode and the second electrode; and a control unit for measuring the applied voltages, calculating the amount of reference charging time it takes to reach a second voltage from a predetermined first voltage on the basis of the measured voltages, and determining water level on the basis of the calculated reference charging time.

Abstract: Provided herein are compounds, pharmaceutical compositions, methods, and kits for treating viral infections (e.g., Dengue viral infections). In certain embodiments, compounds useful in the methods described herein are of Formula (I) or (II).

Abstract: The present invention relates to a cell induction method, in particular to a method for inducing differentiation of fibroblasts into adipocytes, comprising the following steps: Cultivating the fibroblasts in a culture medium, adding a Myosin inhibitor and BMP4 to the culture medium, and continuously cultivating same until adipocytes are obtained. The present invention further relates to a method for inducing the conversion of fibroblasts into immortalized cells and use thereof. The method comprises the following steps: cultivating the fibroblasts in a culture medium, adding Myosin inhibitor to the culture medium, and continuously cultivating same until immortalized cells are obtained. The present invention further relates to a method for inducing in vitro amplification of hepatocytes.

Abstract: The present invention relates to methods for targeted editing in a plant, a plant cell or material, which is combined with the parallel introduction of a phenotypically selectable trait. Furthermore, methods are provided not comprising a step of introducing a transgenic selection marker sequence.

Abstract: The present disclosure provides a water-blocking device including a water-blocking plate installed on a floor of a passage, rails installed on both sidewalls of the floor, and a driving part configured to lift and lower the water-blocking plate, wherein, when the driving part is operated, the water-blocking plate is lifted and lowered along the rails.

Abstract: Systems and methods to remediate, degrade, and/or remove pollutants within various contaminated environmental solid media that includes contaminated soils and sediments, biosolids and slurries by subjecting a mixture of the contaminated solids and a liquid to acoustic cavitation generated by more than one type of ultrasonic device. One of the ultrasonic devices operates at a low frequency and the other ultrasonic device operates at a high frequency.

Abstract: A boltless fastener assembly for a heavy haul railway with an axle load of 35-40 tons includes a pre-embedded steel holder, an e-clip, an insulated gauge block and a rubber pad. A clamping leg-heel end of the e-clip is provided with an L-shaped retaining end. The pre-embedded steel holder is improved to adapt to the e-clip, and an opening is formed at a portion of the pre-embedded steel holder close to the clamping leg-heel end of the e-clip, so that the e-clip can be installed normally. During normal installation, the L-shaped retaining end of the e-clip does not contact the pre-embedded steel holder. When the rail undergoes large torsional deformation, the L-shaped retaining end on one side of a rail moves upward to contact an upper edge of the opening of the pre-embedded steel holder or engages with a second heel end.

Abstract: The present invention provides universal immunotherapy compositions useful for targeted treatment of cancers.

Abstract: An inspection apparatus for inspecting a light-emitting diode wafer is provided. The inspection apparatus includes a Z-axis translation stage, a sensing probe, a height measurement module, a carrier, an illumination light source, and a processing device. The sensing probe is integrated with the Z-axis translation stage. The Z-axis translation stage is adapted to drive the sensing probe to move in a Z axis. The sensing probe includes a photoelectric sensor, a beam splitter, and a photoelectric sensing structure. One of the photoelectric sensor of the sensing probe and the height measurement module is adapted to receive a light beam penetrating the beam splitter, and the other one of the photoelectric sensor of the sensing probe and the height measurement module is adapted to receive a light beam reflected by the beam splitter. The carrier is configured to carry the light-emitting diode wafer. The illumination light source is configured to emit an illumination beam to irradiate the light-emitting diode wafer.

Abstract: Disclosed herein are programmable, conditionally activated small interfering RNA constructs (Cond-siRNAs) and methods of making and using the same as therapeutic agents. The Cond-siRNA comprises a sensor strand, a core strand, and a guide strand, which crossover to form a sensor duplex and a RNAi duplex attached to each other to form a single structure. Upon binding an input strand to the sensor strand, the Cond-siRNA is activated and releases RNAi targeting a desired gene.