Patents Assigned to INSTITUTE
  • Patent number: 9447054
    Abstract: Disclosed is an anticancer supplement agent including a benzo[d]oxazole derivative as an effective ingredient. The benzo[d]oxazole derivative, which is a nuclear factor E2-related factor 2 (Nrf2) inhibitor, is capable of inhibiting activity of Nrf2 that induces an antioxidant enzyme to remove reactive oxygen species (ROS) that kills a cancer cell, thereby increasing production of ROS. Therefore, the benzo[d]oxazole derivative can be used as an anticancer supplement agent that shows therapeutic effects in anticancer agent therapy or radiation therapy, and in this regard, the benzo[d]oxazole derivative can overcome tolerance of the cancer cell to anticancer agent therapy or radiation therapy and enhance apoptotic effects on the cancer cell.
    Type: Grant
    Filed: January 7, 2015
    Date of Patent: September 20, 2016
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jie Young Song, Ji Yeon Ahn, In Sung Jung, Saelooom Lee, Arang Son, Ky Youb Nam, Hyun Kyung Choi, Seung Yong Seo, Yuan Yue
  • Patent number: 9446370
    Abstract: The invention relates to a reactor system, comprising a heat-exchange unit and a reaction unit that are assembled together into a structure. The heat-exchange unit has a plurality of plate or corrugated-plate heat exchangers, and is formed so as to attachable/detachable to/from the reaction unit and insertable into the latter. Accordingly, a catalyst may be attached to a heat-transfer surface of a heat exchanger by a washcoat method or the like, thus maximizing heat-transfer efficiency and enabling the easy removal or reattachment of the catalyst when the enabling the easy removal or reattachment of the catalyst at the end of the lifespan of the catalyst.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: September 20, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Kyoung Su Ha, Geun Jae Kwak, Jae-Hoon Jung, Joo Young Cheon, Ki Won Jun
  • Patent number: 9446273
    Abstract: Disclosed is a method of detoxifying asbestos of waste slate. The method includes concentrating the asbestos by introducing hydrochloric acid aqueous solution into waste slate powder to dissolve and remove a limestone component contained in the waste slate; and mixing the concentrated asbestos with oxalic acid and performing a low-temperature heat treatment. The waste slate is crushed and pulverized and powder of the crushed and pulverized waste slate is formed in a size in a range of 100 meshes to 300 meshes. The detoxified asbestos includes re-crystallized magnesium oxalate having a rhombohedral or amorphous shape.
    Type: Grant
    Filed: June 19, 2014
    Date of Patent: September 20, 2016
    Assignee: KOREA INSTITUTE OF GEOSCIENCE AND MINERAL RESOURCE
    Inventors: Young-Nam Jang, Kyungsun Song, Myung Gyu Lee, Soo-Chun Chae, Hwanju Jo, Jun-Hwan Bang, Kyoung Won Ryu
  • Patent number: 9450368
    Abstract: The present invention relates to a pulse laser device, and more particularly, to a pulse laser device which can be operated in a burst mode, in which the output of a low-output laser generator is adjusted so as to enable the uniform control of the profile of the peak output of a final output optical pulse train, and in a variable burst mode, in which the profile of the final output optical pulse train can be controlled into an arbitrary waveform.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: September 20, 2016
    Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Young-Chul Noh, Woojin Shin, Bong-Ahn Yu, Yeung Lak Lee, Changsoo Jung
  • Patent number: 9449597
    Abstract: An ultrasound receiving method is provided. N return-wave signals corresponding to N channels are respectively stored in N set of shift register arrays. Each set includes a delay filter unit and M shift registers. A delay controller is utilized to assign a set of coefficients to the delay filter unit to perform an interpolation operation on data of the M shift registers to obtain an output value. The delay controller is utilized to decide delay time of each channel according to a delay table, and accordingly to control a time multiplexer to switch and output the N output values in order. A multiplier is utilized to multiply the output value received from the time multiplexer by a weighted value corresponding to the channel to obtain a corrected value. An accumulator is utilized to accumulate the N corrected values to obtain an image value.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: September 20, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventor: Chien-Ju Li
  • Patent number: 9447062
    Abstract: A manumycin-type metabolite called Colabomycin E which inhibits caspase 1 and creation of interleukins, strain produces the Colabomycin E and a method of a production of the Colabomycin E. Colabomycin E is a new member of the manumycin-type metabolites produced by the strain Streptomyces aureus SOK1/5-04 deposited in The Czech collection of microorganisms under number CCM8556. The structure of 5 is similar to that of the already known metabolite colabomycin A (3) isolated from Streptomyces griseoflavus. However, the upper polyene chain of 5 is two carbons longer. Therefore, it was named Colabomycin E. Biological activity assays indicated that colabomycin E significantly inhibited IL-1? release from THP-1 cells and might thus potentially act as an anti-inflammatory agent.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: September 20, 2016
    Assignees: BIOLOGY CENTRE AS CR, V.V.I., INSTITUTE OF MICROBIOLOGYH AS CR, V.V.I., INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE
    Inventors: Miroslav Petricek, Katerina Petrickova, Stanislav Pospisil, Marek Kuzma, Alica Chronakova, Vaclav Kristufek, Ilja Striz
  • Patent number: 9447063
    Abstract: The present invention relates to a novel disubstituted adamantyl derivative or the pharmaceutically acceptable salts thereof, a method for preparing the same, and a pharmaceutical anticancer or antimetastasis composition comprising the same as an active ingredient. The disubstituted adamantyl derivative of the present invention suppressed accumulation of HIF-1?, inhibiting the expression of the metastasis related protein Twist dose-dependently. Thus, the disubstituted adamantyl derivative of the invention is effective in inhibiting the expressions of the metastasis related proteins, ?-catenin and RohA, and the EMT related genes such as MMP2 and MMP9, without cytotoxicity. Therefore, the disubstituted adamantyl derivative or the pharmaceutically acceptable salts thereof of the invention can be efficiently used as a pharmaceutical anticancer or antimetastasis composition.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: September 20, 2016
    Assignees: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Mi Sun Won, Kyeong Lee, Bo Kyung Kim, Hyun Seung Ban, Seohyun Son, Kyung-Sook Chung
  • Patent number: 9450611
    Abstract: A low density parity check (LDPC) encoder, an LDPC decoder, and an LDPC encoding method are disclosed. The LDPC encoder includes first memory, second memory, and a processor. The first memory stores an LDPC codeword having a length of 64800 and a code rate of 7/15. The second memory is initialized to 0. The processor generates the LDPC codeword corresponding to information bits by performing accumulation with respect to the second memory using a sequence corresponding to a parity check matrix (PCM).
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: September 20, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sung-Ik Park, Heung-Mook Kim, Sun-Hyoung Kwon, Nam-Ho Hur
  • Patent number: 9447945
    Abstract: A light-emitting apparatus includes a substrate, a light source configured to emit light and arranged on the substrate, a phosphor layer being apart from the light source and configured to convert the light into forward transmitted light and backward transmitted light, and an optic device, being narrower than the substrate and having a transparent side wall, configured to direct at least a portion of the backward transmitted light through the transparent side wall and toward the substrate. In another aspect, a light-emitting apparatus includes a transparent base, a light source on the transparent base, a transparent material covering the light source, a phosphor layer on the transparent material, and a transparent wall on the phosphor layer.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: September 20, 2016
    Assignee: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: Nadarajah Narendran, Yimin Gu
  • Patent number: 9448874
    Abstract: An apparatus and method that prevent a bit error in a static random access memory (SRAM)-based Physically Unclonable function (PUF). The method for preventing an error in a PUF includes selecting any value, from a physically unclonable function based on a volatile memory device, as an input value, and checking a response corresponding to the selected input value, classifying cells having a plurality of bits corresponding to the response depending on frequency of error occurrence, calculating a number of white cells, in which an error does not occur, from classified results, and determining whether the number of white cells is greater than a preset threshold number of white cells, and selecting an input value of the physically unclonable function based on results of determination.
    Type: Grant
    Filed: May 17, 2015
    Date of Patent: September 20, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Moon-Seok Kim, Sang-Kyung Yoo, Seok Ryu, Bong Soo Lee, Rae Lee, Junki Kang, Sanghan Lee
  • Patent number: 9446381
    Abstract: This disclosures provides an adsorbent which, on the basis of the total weight of the adsorbent, comprises: 1) a Si—Al molecular sieve having an A-FAU structure, wherein A represents a monovalent cation, in an amount of 1-20 wt %, 2) at least one binder selected from the group consisting of titanium dioxide, stannic oxide, zirconium oxide and alumina, in an amount of 3-35 wt %, 3) a silica source, in an amount of 5-40 wt %, 4) zinc oxide, in an amount of 10-80 wt %, and 5) at least one promoter metal selected from the group consisting of cobalt, nickel, iron and manganese, based on the metal, in an amount of 5-30 wt %, wherein at least 10 wt % of the promoter metal is present in a reduced valence state. This adsorbent exhibits improved activity and stability, and at the same time, is capable of significantly improving the octane number of the product gasoline.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: September 20, 2016
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC
    Inventors: Wei Lin, Huiping Tian, Zhenbo Wang
  • Patent number: 9451685
    Abstract: The purpose of the present invention is to solve the problems of conventional high frequency plasma torches and develop a plasma torch which enables quick quenching of high frequency plasma and which overcomes instability resulting from the quick quenching. To accomplish the abovementioned objective, according to one embodiment of the present invention, disclosed is an electromagnetic wave high frequency hybrid plasma torch.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: September 20, 2016
    Assignee: KOREA BASIC SCIENCE INSTITUTE
    Inventors: Yong-Cheol Hong, Jung-Sik Yoon, Ji-Hun Kim
  • Patent number: 9447050
    Abstract: The present invention provides forms of curcumin and the pharmaceutical compositions thereof. The forms of curcumin disclosed herein are curcumin polymorph Form III, curcumin-2-aminobenzimidazole co-crystal, and curcumin-L-lysine co-crystal. Further, the invention provides methods inhibiting cancer cells and HSV-1 using these curcumin novel solid forms.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: September 20, 2016
    Assignees: THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, VAN ANDEL RESEARCH INSTITUTE
    Inventors: Stephen T. Gately, Steven J. Triezenberg, Tong Wang
  • Patent number: 9447553
    Abstract: A shear connector for corrugated sheet steel and concrete, comprises a flange plate welded at an upper end portion of the corrugated sheet steel, with more than one U-shaped steel channel welded in the longitudinal direction at an upper edge of the flange plate, the channel walls of each U-shaped steel channel being provided with two longitudinal sides, the left and right sides of the front and rear channel walls being respectively provided with corresponding holes or grooves, the left and right sides of the front and rear channel walls being respectively provided with corresponding holes or grooves, which penetrates and connects each of the steel channels; in the holes or grooves on the left and right sides of each U-shaped steel channel respectively, a vertically bent steel bar is provided, a bottom steel bar of each of the vertically bent steel bars penetrating the holes or grooves on the left or the right side in a longitudinal direction, both ends of the bottom steel bar being respectively bent upwards a
    Type: Grant
    Filed: July 26, 2012
    Date of Patent: September 20, 2016
    Assignee: JIANGSU TRANSPORTATION RESEARCH INSTITUTE CO., LTD.
    Inventors: Jiandong Zhang, Xinzheng Liang, Xin Wang, Duo Liu, Huaiyu Hu, Jingkun Ji
  • Patent number: 9450800
    Abstract: In order to suppress out-of-band radiation within a range of a spectrum mask regulation without reducing transmission signal power or the like even when a wireless communication is performed in a white space by using OFDM or the like, the present invention is characterized by including an RF circuit characteristic analysis unit, a multipath delay detection unit, a digital filter setting unit, and a transmission power setting unit and further including: a windowing function/windowing duration selection unit configured to select a windowing function and a windowing duration based on the analysis result by the RF circuit characteristic analysis unit, the detection result by the multipath delay detection unit, and the setting by the digital filter setting unit and the transmission power setting unit; a guard interval duration selection unit configured to select a guard interval duration; and a transmission power selection unit configured to select transmission power.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: September 20, 2016
    Assignee: NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY
    Inventors: Ryuhei Funada, Keiichi Mizutani, Hiroshi Harada
  • Publication number: 20160264551
    Abstract: The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., cyclin-dependent kinase 7 (CDK7)), and therefore, in duce cellular apoptosis and/or inhibit transcription in the subject.
    Type: Application
    Filed: October 17, 2014
    Publication date: September 15, 2016
    Applicants: SYROS PHARMACEUTICALS, INC., DANA-FARBER CANCER INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Stephane Ciblat, Patrick Deroy, Nathanael Gray, Melissa Leblanc, Jason J. Marineau, Joel Moore, Kevin Sprott, Tinghu Zhang, M. Arshad Siddiqui, Anzhelika Kabro, Serge Leger, Tom Miller, Stephanie Roy, Darby Schmidt, Dana K. Winter, Michael Bradley
  • Publication number: 20160265007
    Abstract: The invention provides a process for producing 3-hydroxybutyric acid or a salt thereof, the process comprising culturing one or more halophilic bacteria belonging to the genus Halomonas under specific conditions.
    Type: Application
    Filed: November 11, 2014
    Publication date: September 15, 2016
    Applicants: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, OSAKA GAS CO., LTD.
    Inventors: Yoshikazu KAWATA, Jun TSUBOTA, Isao MATSUSHITA
  • Publication number: 20160264631
    Abstract: The present invention provides proteins that are suitable to be used as the active ingredient in subunit vaccine against Mycoplasma spp. The present invention also provides a subunit vaccine made therefrom. Said proteins have been experimentally proved to have the capability of inducing sufficient immune response to avoid pigs from Mycoplasma spp. infection. Said vaccine may have one of said proteins as active ingredient; or may have two or more of said proteins and is formulated as a cocktail vaccine. The present vaccine not only is safer than the conventional vaccines but also has equal or even better immune efficiency than the conventional ones. Furthermore, fusion partners suitable for producing said proteins of high solubility are also proved, which can significantly reduce production cost.
    Type: Application
    Filed: November 21, 2013
    Publication date: September 15, 2016
    Applicant: AGRICULTURAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: JIUNN-HORNG LIN, JYH-PERNG WANG, ZENG-WENG CHEN, CHIEN-YU FANG, MING-WEI HSIEH, PING-CHENG YANG
  • Publication number: 20160266670
    Abstract: A touch device is provided. The touch device includes a first insulating layer, a first sensing electrode layer, a second insulating layer, and a second sensing electrode layer. The first sensing electrode layer is located on the first insulating layer. The second insulating layer is located on the first sensing electrode layer. The second sensing electrode layer is located on the second insulating layer.
    Type: Application
    Filed: July 20, 2015
    Publication date: September 15, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Sin-An CHEN, Chih-Chia CHANG
  • Publication number: 20160265349
    Abstract: Methods and apparatus for transmitting power and data along a metal pipe using wideband acoustic waves. Arrangements use shear-horizontal waves, transmitting narrowband signals for power applications and wideband signals for communications having a bandwidth greater than the coherence bandwidth of the acoustic-electric channel. Chirp wave signals, direct sequence spread signals, and on-off keying are used. Acoustic-electric channels include wedges fixed to a pipe or other substrate, transducers fixed to the wedges, and electronics linked to each transducer for sending and receiving power and signals. Matching networks, rectification circuits, and non-coherent signal reception methods may be used.
    Type: Application
    Filed: March 24, 2015
    Publication date: September 15, 2016
    Applicant: RENSSELAER POLYTECHNIC INSTITUTE
    Inventors: GARY J. SAULNIER, Kyle R. Wilt, R. Benjamin Litman, Henry A. Scarton, Soumya Chakraborty