Abstract: The present application relates broadly neutralizing monoclonal antibodies directed against HIV-1. In particular, monoclonal antibodies VRC-PG04 and VRC-PG05 are disclosed.
Type:
Grant
Filed:
March 10, 2013
Date of Patent:
July 5, 2016
Assignees:
INTERNATIONAL AIDS VACCINE INITIATIVE, THE SCRIPPS RESEARCH INSTITUTE, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Inventors:
John Mascola, Dennis R. Burton, Wayne Koff, Peter Kwong, Gary Nabel, Sanjay K. Phogat, Pascal Raymond Georges Poignard, Melissa Danielle De Jean St. Marcel Simek-Lemos, Xueling Wu, Tongqing Zhou, Zhi-Yong Yang
Abstract: This invention relates to a beam steering mechanism with ultrahigh frequency response and high sensitivity, which is based on the translation of two mirrors. Beam steering is achieved by the translations of two mirrors in the X axial mirror group and Y axial mirror group. The two translation mirrors are located at the output ends of two PZT actuators, and are directly actuated by the two PZT actuators. The dynamic characteristics of the two translation mirrors are always exactly the same as the output characteristics of the PZT actuators. There is no mechanical translation loss in this beam steering mechanism, and so, the beam steering mechanism has an ultrahigh frequency response and high angular deflection sensitivity.
Abstract: A combined-type intelligent terminal wiring device and a plug device are provided. The wiring device includes a top wiring terminal board, a bottom wiring terminal board and a combined-type socket. An interior of each terminal of the combined-type socket has a spring-leaf structure, and each spring leaf includes an upper spring leaf and a lower spring leaf which are conductively connected via a contact surface. The top wiring terminal board has one end configured to connect the upper spring leaf, and the bottom wiring terminal board has one end configured to connect the lower spring leaf. The plug device includes a plug and a wiring terminal, the plug is located at a front end of the plug device and is a conductive metallic sheet, and the wiring terminal is located at a rear end of the plug device and has one end connected to the conductive metallic sheet.
Type:
Grant
Filed:
September 10, 2013
Date of Patent:
July 5, 2016
Assignees:
STATE GRID CORPORATION OF CHINA (SGCC), STATE GRID CHONGQING ELECTRIC POWER CO. ELECTRIC POWER RESEARCH INSTITUTE
Inventors:
Guojun He, Xingzhe Hou, Yingying Cheng, Huaxiao Yang, Ji Xiao, Jianming Hu, Ke Zheng, Xiaorui Hu, Xiyang Ou, Jing Liu
Abstract: A Unified Speech and Audio Codec (USAC) that may process a window sequence based on mode switching is provided. The USAC may perform encoding or decoding by overlapping between frames based on a folding point when mode switching occurs. The USAC may process different window sequences for each situation to perform encoding or decoding, and thereby may improve a coding efficiency.
Type:
Grant
Filed:
January 2, 2015
Date of Patent:
July 5, 2016
Assignees:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, KWANGWOON UNIVERSITY INDUSTRY-ACADEMIC COLLOBARATION FOUNDATION
Inventors:
Seungkwon Beack, Tae Jin Lee, Min Je Kim, Kyeongok Kang, Dae Young Jang, Jeongil Seo, Jin Woo Hong, Chieteuk Ahn, Ho Chong Park, Young-cheol Park
Abstract: Provided is a composition for treating diabetes, including a hypoglycemic agent and a Yukmijihwang-tang extract. More particularly, the hypoglycemic agent is administered into an individual, and the Yukmijihwang-tang extract is administered into the individual, thereby considerably increasing a hypoglycemic effect of the hypoglycemic agent, and preventing and reducing various diabetic complications such as diabetes and diabetic liver damage, renal damage, hyperlipidemia immunosuppression and ocular damage.
Type:
Application
Filed:
May 2, 2014
Publication date:
June 30, 2016
Applicant:
COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
Inventors:
Seok Bong KANG, Ho Sang SOHN, Joon Seok BYUN, Ki Cheul SOHN, Sae Kwang KU
Abstract: Provided is a data transmission method using physical network coding in a relay station. The method may include an operation of receiving a first signal and a second signal from first and the second nodes, respectively, an operation of generating a third signal to which a physical network coding is applied based on the first signal and the second signal, an operation of forming a beam which maximizes a lower effective power between effective power of the first channel between the relay station and the first node and effective power of the second channel between the relay station and the second node, and an operation of transmitting the third signal to the first node and the second node based on the beam.
Type:
Application
Filed:
December 29, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Provided is an antenna structure including a substrate and a driven element, a reflector, and a director, which are disposed on the substrate, and respectively configured to transmit/receive, reflect, and direct an electric wave having a first wavelength. The driven element includes a first area having a first length in a first direction parallel to a top surface of the substrate, and a second area having the first length in the first direction and spaced apart from the first area in the first direction. Each of the first area and the second area is a PIN diode that is formed by doping an upper portion of the substrate.
Type:
Application
Filed:
December 29, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECELECTROOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
CHEOL HO KIM, KWANGCHUN LEE, DONGSEUNG KWON, BONG HYUK PARK
Abstract: Disclosed is a method for assigning a radio resource. The method includes: measuring an interference or a noise level for a signal outputted from neighboring base stations and generating interference information corresponding to the measured value; receiving a frequency assignment list which is available for access for each interference state of a terminal from a serving base station via a control channel; selecting specific frequency assignment information from among the frequency assignment list based on the interference information; transmitting the selected frequency assignment information to the base station; and being assigned the radio resource by the base station based on the selected frequency assignment information.
Type:
Application
Filed:
November 30, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: A resin composition formed by reacting a polyester-polyacid oligomer with a poly-epoxy oligomer is provided. The functionality of the resin composition is between 4 and 10. The weight average molecular weight of the resin composition is between 3,000 and 20,000 g/mol.
Type:
Application
Filed:
July 23, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The present invention provides a method of treating cancer in a subject wherein the method comprising administering to the subject an IAP antagonist and a p38 and/or a MK2 inhibitor.
Type:
Application
Filed:
October 5, 2015
Publication date:
June 30, 2016
Applicant:
THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH
Inventors:
Najoua LALAOUI, John Henry SILKE, David Laurence VAUX
Abstract: Various exemplary embodiments of the present invention relate to a base station apparatus including: an information receiving module which receives information used for scheduling from a plurality of terminals corresponding to the base station apparatus; and a scheduler which generates resource allocation information for one shared FA among a plurality of FAs which is available in the base station apparatus based on the received information and applies the generated resource allocation information to at least one other shared FA.
Type:
Application
Filed:
December 29, 2015
Publication date:
June 30, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Disclosed is a polysiloxane being crosslinked from 0.05 to 20 parts by weight of a second silane and an oligomer of 1 part by weight of a first silane. The first silane is Si(R1)2(OR2)2, each R1 is independently acrylic group, epoxy group, vinyl group, amino group, aromatic group, or aliphatic group, and each R2 is independently aliphatic group. The second silane is Si(R3)(OR4)3, R3 is acrylic group, epoxy group, vinyl group, amino group, aromatic group, or aliphatic group, and each R4 is independently aliphatic group.
Type:
Application
Filed:
December 24, 2014
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: A modified cellulose is provided. The modified cellulose is represented by the chemical formula (1): wherein n is between 60 and 2500, at least one R is selected from one of the group consisting of R1 is C11 to C32 alkyl group or C11 to C32 alkenyl group, R2 is hydrogen, C3 to C29 alkyl group or C3 to C29 alkenyl group, R3 is C3 to C29 alkyl group or C3 to C29 alkenyl group, R4 is C4 to C8 cycloalkyl group or C4 to C8 cycloalkenyl group, n2 is between 15 and 33, n4 is between 20 and 40.
Type:
Application
Filed:
December 10, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: Provided is an autonomous vehicle assistance device and method that may precisely determine a position of a vehicle based on input position error information. The autonomous vehicle assistance device includes a communicator configured to receive satellite navigation information, correction information transmitted from a base station, and position error information transmitted from a fixed body, and a vehicle position determiner configured to calculate first position information corresponding to the received satellite navigation information and correction information and to calculate a current position of a vehicle by correcting the first position information based on the position error information.
Abstract: Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang. More particularly, provided is a composition for treating a neoplastic disease by administering an anticancer agent into an individual, and administering an oriental medicine into the individual within 30 minutes. The composition remarkably reduces side effects occurring when the anticancer agent is administered alone by co-administration of the oriental medicine, reduces cytotoxicity, and has higher anticancer activity than that when the anticancer agent is administered alone.
Type:
Application
Filed:
May 15, 2014
Publication date:
June 30, 2016
Applicant:
COMPREHENSIVE AND INTEGRATIVE MEDICINE INSTITUTE
Inventors:
Joon Seok BYUN, Sae Kwang KU, Ki Cheul SOHN, Seung Mo KIM, Chang Hyeong LEE, Dae Sung HYUN, Jong Dae Kim, Sung Hwan PARK, Min A. KWAK
Abstract: According to one embodiment of the present invention, the light emitting device includes an LED element, a side wall which surrounds the LED element, a phosphor layer which is fixed to the side wall with an adhesive layer therebetween, and is positioned above the LED element, and a metal pad as a heat dissipating member. The side wall includes an insulating base which surrounds the LED element and a metal layer which is formed on a side surface at the LED element side of the base, and is in contact with the metal pad and the adhesive layer. The adhesive layer includes a resin layer that includes a resin containing particles which have higher thermal conductivity than the resin or a layer that includes solder.
Type:
Application
Filed:
August 8, 2014
Publication date:
June 30, 2016
Applicants:
KOHA CO., LTD., TAMURA CORPORATION, NATIONAL INSTITUTE FOR MATERIALS SCIENCE
Abstract: The present invention relates to a method of treating a warm-blooded animal, especially a human, having Mixed Lineage Leukemia (MLL rearranged ALL) comprising administering to said animal a therapeutically effective amount of a staurosporine derivative, especially PKC412 or a pharmaceutically acceptable salt thereof, alone or in combination with further therapeutic measures, for example, those defined herein; to the use of a staurosporine derivative for the preparation of a medicament for the treatment of MLL rearranged ALL; and to a commercial package comprising a staurosporine derivative together with instructions for its use in the treatment of MLL rearranged ALL.
Type:
Application
Filed:
October 30, 2015
Publication date:
June 30, 2016
Applicants:
DANA-FARBER CANCER INSTITUTE INC., NOVARTIS AG
Abstract: An RSSI positioning method based on frequency-hopping spread spectrum technology, comprising: calibration stage: measuring the RSSI values of a plurality of channels at fixed points, and recording and calculating the ranging parameters in an RSSI ranging model; system preparation: deploying a positioning anchor node, and realizing synchronization between a target node and the anchor node; conducting communication on the target node by respectively utilizing a plurality of channels to obtain the RSSI values; signal processing stage: processing the RSSI into signal strength amplitude and performing optimization; and positioning stage: calculating a distance and the target node position on a positioning server according to each of the signal strength.
Type:
Application
Filed:
August 27, 2014
Publication date:
June 30, 2016
Applicant:
SHENYANG INSTITUTE OF AUTOMATION OF THE CHINESE ACADEMY OF SCIENCES
Inventors:
Peng ZENG, Jinchao XIAO, Jie HE, Haibin YU
Abstract: In one aspect, the present disclosure provides new analogs of uncialamycin of formulae (I) and (II). The present disclosure also provides novel synthetic pathways to obtaining uncialamycin and analogs thereof. Additionally, the present disclosure also describes methods of use of uncialamycin and analogs thereof. In another aspect, the present disclosure provides antibody-drug conjugates comprising the compounds of formulae (I) and (II).
Type:
Application
Filed:
August 14, 2014
Publication date:
June 30, 2016
Applicants:
WILLIAM MARSH RICE UNIVERSITY, BRISTOL-MYERS SQUIBB COMPANY, THE SCRIPPS RESEARCH INSTITUTE
Inventors:
Kyriacos C. NICOLAOU, Min LU, Debashis MANDAL, Sanjeev GANGWAR, Naidu S. CHOWDARI, Yam B. POUDEL
Abstract: A compound, and a polymer prepared therefrom, are provided. The compound has a structure represented by Formula (I) or Formula (II): wherein A is R1 is C1-10 alkyl, C5-12 cycloalkyl, C6-14 aryl, C3-12 heteroaryl, C1-10 alkoxy, C6-12 aryloxy, C1-10 silyl, amino, thiol, or phosphonate group; R2 is H, or C1-10 alkyl; and, R3 is C1-10 alkoxy, C1-10 alkanol, amine, or hydroxy.
Type:
Application
Filed:
September 10, 2015
Publication date:
June 30, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE