Patents Assigned to INSTITUTE
  • Patent number: 10933085
    Abstract: The present invention provides compositions comprising hyaluronan with high elasticity, as well as methods for improving joint function, reducing pain associated with joint function and treating osteoarthritis by introducing into a joint a therapeutically effective amount of a composition comprising hyaluronan with high elasticity.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: March 2, 2021
    Assignee: Matrix Biology Institute
    Inventors: Endre A. Balazs, Carlos Belmonte
  • Patent number: 10933240
    Abstract: Methods for electrical modulation of inflammation or serum TNF levels in a subject.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: March 2, 2021
    Assignee: The Feinstein Institutes for Medical Research
    Inventors: Adam M. Kressel, Valentin A. Pavlov, Sangeeta S. Chavan, Kevin J. Tracey
  • Patent number: 10935424
    Abstract: A spectral measurement device capable of achieving a high level of diffraction efficiency by reducing the polarization sensitivity of the device. Many such embodiments are capable of achieving high diffraction efficiency by fixing the polarization of the incoming light to a fixed polarized state internal to the device, thereby allowing for the full spectrum of light to be captured and measured by the device.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: March 2, 2021
    Assignee: California Institute of Technology
    Inventor: James K. Wallace
  • Patent number: 10934593
    Abstract: The present invention relates to compositions and methods for detecting CDK4/6 response and resistance.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: March 2, 2021
    Assignee: DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Liam Cornell, Geoffrey I. Shapiro
  • Patent number: 10933232
    Abstract: An anchor device is described that is adapted to support one or more conductors extending out of an opening in an outer surface of an eye, from a device implanted in the eye to a communications interface. The anchor device comprises a conductor receiving portion including a channel, the conductors being positionable through the channel; and a fixation portion connected to the conductor receiving portion, the fixation portion being adapted to be secured to the outer surface of the eye. The conductor receiving portion is configured to allow movement of the channel and/or conductors relative to the fixation portion. A visual prosthesis comprising the anchor device is also described, along with apparatus and methods for positioning the visual prosthesis or other types of implantable electrical apparatus.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: March 2, 2021
    Assignee: The Bionics Institute of Australia
    Inventors: Christopher Edward Williams, Joel Villalobos Villa, Owen Burns
  • Patent number: 10934373
    Abstract: Provided are use of organosilane, and polyolefin resin and preparation method thereof. The method of preparing the polyolefin resin comprises: conducting olefin polymerization of olefin monomers in the presence of a catalyst, and adding organosilane to a polymerization system before the olefin polymerization and/or during the olefin polymerization, wherein the organosilane is represented by a general formula of R1mSiXn(OR2)k, wherein R1 is a C2-C20 alkyl, and a terminal of R1 has an ?-olefin double bond, a norbornene group, a cycloalkene group, or a dicyclopentadiene group; X is a halogen element; R2 is a C1-C20 straight chain, a C1-C20 branched chain, or an isomerized alkyl group; m is an integer from 1-3; n is an integer from 1-3; k is an integer from 0-2; and m, n, and k satisfy the following condition: m+n+k=4. The polyolefin resin obtained by the above method has higher melt strength and mechanical strength.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: March 2, 2021
    Assignees: INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES, UNIVERSITY OF CHINESE ACADEMY OF SCIENCES
    Inventors: Jinyong Dong, Yawei Qin
  • Patent number: 10933139
    Abstract: The present invention provides inventive conjugated polyethyleneimine (PEI) polymers and conjugated aza-macrocycles (collectively referred to herein as “conjugated lipomers” or “lipomers”) containing one or more groups of the formula (iii): wherein R3 and R4 are as defined herein. Also provided are compositions comprising the inventive conjugated lipomers, and methods of preparation and use.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: March 2, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: James E. Dahlman, Avraham D. Schroeder, Daniel Griffith Anderson, Robert S. Langer, Christopher G. Levins
  • Patent number: 10934283
    Abstract: Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: March 2, 2021
    Assignee: LIEBER INSTITUTE, INC.
    Inventors: James Barrow, Glen Ernst, Dominique Swinnen, Florian Montel, Sabine Defays, Yifang Huang, Pablo de León, Michael Steven Poslusney
  • Patent number: 10935741
    Abstract: Provided is an optical module including an optical waveguide device through which multiple channel lightwaves are input and output, an optical transmission/reception unit disposed on one side of the optical waveguide device, an electronic IC disposed on one side of the optical transmission/reception unit and configured to drive the optical transmission/reception unit, a flexible printed circuit board (PCB) disposed on the optical transmission/reception unit and the electronic IC, a first solder ball between the optical transmission/reception unit and the flexible PCB and a second solder ball between the electronic IC and the flexible PCB.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: March 2, 2021
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Young-Tak Han, Seok-Tae Kim, Jong-Hoi Kim, Sang-Ho Park, Yongsoon Baek, Jang-Uk Shin, Seo-Young Lee
  • Patent number: 10938310
    Abstract: A DC-DC power converter has an auxiliary tank cascaded to share an efficiency tank's inductor, capacitor, and transformer. Switching transistors pump the auxiliary tank at startup to provide a boost current. The switching frequency is reduced in steps and the voltage gain and power of the converter sensed until the voltage gain matches a voltage gain calculated for the efficiency tank. Then tank switchover occurs and transistors to the efficiency tank are pumped with the last switching frequency used by the auxiliary tank, and the auxiliary tank is not pumped. Since the voltage gains before and after tank switchover are equal, no output voltage deviation or current spike occurs. A voltage sag or failure switches back to the auxiliary tank at a switching frequency determined by a dynamic contour line where the voltage gains of the two tanks are equal for the current power state.
    Type: Grant
    Filed: January 2, 2020
    Date of Patent: March 2, 2021
    Assignee: Hong Kong Applied Science and Technology Research Institute Company, Limited
    Inventors: Chi Man Cheng, Shek Mong Wong, Tak Lok Shum
  • Patent number: 10935655
    Abstract: A system may include a surface penetrating radar system. The system may further include a battery system of a vehicle. At least a portion of the battery system of the vehicle may also be at least a portion of the surface penetrating radar system.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: March 2, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventor: Byron McCall Stanley
  • Patent number: 10936664
    Abstract: A dialogue system includes: a question generating unit receiving an input sentence from a user and generating a question using an expression included in the input sentence, by using a dependency relation; an answer obtaining unit inputting the question generated by the question generating unit to a question-answering system and obtaining an answer to the question from question-answering system; and an utterance generating unit for generating an output sentence to the input sentence, based on the answer obtained by the answer obtaining unit.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: March 2, 2021
    Assignee: National Institute of Information and Communications Technology
    Inventors: Noriyuki Abe, Kanako Onishi, Kentaro Torisawa, Canasai Kruengkrai, Jonghoon Oh, Ryu Iida, Yutaka Kidawara
  • Patent number: 10937175
    Abstract: The method for assisting a person in operating in a dynamic environment may form part of a mobility assistance system. The method comprises a step of acquiring sensor data comprising a time sequence of at least two consecutive images of the dynamic environment from at least one sensor, for example a camera. Optical flows are calculated based on the at least two consecutive images. Feature scores associated to spatial positions for selected regions in an image space are determined in order to generate a feature score field. An output signal including directional stimulus information is generated based on the generated feature score field, wherein the directional stimulus information comprises information on relative spatial relations between the selected regions. The generated output signal is provided to at least one actuator, which signals the directional stimulus information to the person.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: March 2, 2021
    Assignee: HONDA RESEARCH INSTITUTE EUROPE GMBH
    Inventors: Matti Kruger, Heiko Wersing, Julian Eggert
  • Patent number: 10934408
    Abstract: The present invention relates to a surface modification method for a polyether-ether-ketone material. The method combines physical and chemical methods, and comprises the steps of performing plasma immersion ion implantation on the surface of the polyether-ether-ketone material with argon as an ion source, and then, soaking the polyether-ether-ketone material treated by plasma immersion ion implantation in a hydrogen peroxide aqueous solution, hydrofluoric acid aqueous solution, or ammonia water to make the surface of the modified polyether-ether-ketone material have nanoparticles, shallow nanoporous structures, and/or ravined nanostructures.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: March 2, 2021
    Assignee: SHANGHAI INSTITUTE OF CERAMICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Xuanyong Liu, Tao Lu, Heying Wang, Fanhao Meng
  • Patent number: 10934018
    Abstract: System for reducing likelihood of an aircraft-induced lightning strike on an aircraft. The system includes a plurality of electric field sensors distributed on surfaces of the aircraft to monitor continuously the electrical environment to which the aircraft is subjected. A plurality of ion emission sources are distributed on selected aircraft surfaces, the ion emission sources adapted to emit either positive or negative ions. A computer runs an algorithm to control net charge level of the aircraft by commanding the emission of positive or negative ions from selected surfaces to retard inception of corresponding leader discharges.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: March 2, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Manuel Martinez-Sanchez, Carmen Guerra-Garcia, Ngoc Cuong Nguyen, Jaime Peraire, Theodore Mouratidis
  • Patent number: 10933401
    Abstract: The present invention relates to a magnetic cesium adsorbent, a preparation method therefor, and a cesium removal method using the same, the preparation method comprising the steps of: (a) preparing a metal hexacyanoferrate; and (b) hydrothermally reacting the metal hexacyanoferrate so as to prepare a metal hexacyanoferrate having a rhombohedral crystal structure.
    Type: Grant
    Filed: July 4, 2017
    Date of Patent: March 2, 2021
    Assignee: KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Tae Hong Park, Young Jin Cho, Sang Eun Bae, Sang Ho Lim, Jai Il Park, Young Sang Youn, Jei Won Yeon
  • Patent number: 10933146
    Abstract: The disclosure relates in some aspects to imaging agents, and in particular, imaging agents for sensing of calcium signaling. According to some embodiments of the disclosure, contrast agents for magnetic resonance imaging and related technologies are provided, and methods of making and using the contrast agents.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: March 2, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Alan Pradip Jasanoff, Ali Barandov, Benjamin B. Bartelle
  • Patent number: 10935470
    Abstract: Provided is an ultra microtome device including: a specimen restraint part having a sample holder formed on one side in a length direction, wherein a specimen is mounted on the sample holder; a power part for providing power for implementing a motion of the specimen restraint part; an up and down motion implementing part including a first cam rotated by a force transmitted from the power part and a first shaft for implementing an up and down motion of the specimen restraint part in response to the rotation of the first cam; and a forward and backward motion implementing part including a second cam rotated by the force transmitted from the power part and a second shaft for implementing a forward and backward motion of the specimen restraint part in response to the rotation of the second cam, thereby implementing a more precise motion.
    Type: Grant
    Filed: October 31, 2019
    Date of Patent: March 2, 2021
    Assignee: KOREA BASIC SCIENCE INSTITUTE
    Inventors: Hwan Hur, Hee-Seok Kweon, Kye-Sung Lee
  • Patent number: 10933033
    Abstract: A composition for preventing or reducing nephrotoxicity, and use thereof are provided, the composition including a Hypoxylon truncatum extract or an active component thereof.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: March 2, 2021
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jungyeob Ham, Young Tae Park, Taejung Kim, Young seok Kim, Pilju Choi, Kyusun Kim, SeonJun Choi, BongGeun Song, Kisung Kang, Buyng Su Hwang, Dahae Lee, Jihoon Song
  • Patent number: 10936885
    Abstract: Systems, methods, and other embodiments described herein relate to processing an image having a distortion and an object. The method according to some embodiments includes acquiring an image having a distortion and performing a first object detection analysis on a first portion of the image. Next, the method includes performing an undistortion process on the image, and after, performing a second object detection analysis on a second portion of the image. The second portion of the image is different than the first portion of the image. The method can then combine a first result of the first object detection analysis with a second result of the second object detection analysis.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: March 2, 2021
    Assignee: Toyota Research Institute, Inc.
    Inventor: Junya Ueno