Patents Assigned to INSTITUTE
  • Patent number: 12016726
    Abstract: A flexible ultrasound transducer according to an embodiment of the present disclosure includes a substrate having a central part and a plurality of extended parts extending from the central part; an ultrasound probe disposed at the central part of the substrate to acquire an ultrasound image of a region of interest; and a focused ultrasound output unit disposed at the extended parts of the substrate to output a focused ultrasound to the region of interest, wherein the focused ultrasound output unit disposed at the extended parts of the substrate has a flexible property and is deformable. According to the structure of an embodiment, it is possible to simultaneously achieve ultrasound imaging and ultrasonic therapy such as lesion stimulation or removal through focused ultrasound, and adjust the focal position of focused ultrasound or improve the focal sensitivity through flexible movement.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: June 25, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Byung Chul Lee, Shinyong Shim, Dong-Hyun Kang, Hae Youn Kim, Hyung Min Kim, Ki Joo Pahk, Maesoon Im
  • Patent number: 12016936
    Abstract: The present invention relates to a neovascular-targeting contrast medium composition and a method for preparing same. The neovascular-targeting contrast medium composition according to the present invention exhibits high binding force to neovascularization-associated ?v?3 integrin, excellent tissue permeability and biostability, enables simple measurement in vitro, in vivo, or ex vivo, and thus is effective in the detection of neovascularization and in diagnosing diseases associated therewith, and therefore may be usefully employed in the relevant industries.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: June 25, 2024
    Assignee: KOREA BASIC SCIENCE INSTITUTE
    Inventors: Ki-Yuk Chang, Chan-Woo Kim, Kwan-Soo Hong, Hyun-Seung Lee, Hyun-Min Kim
  • Patent number: 12020427
    Abstract: Objective discrimination of a disease label of a depressive symptom with respect to an active state of a brain is achieved. One means for solving the problems of the present invention is to provide a discriminating device for assisting in determination of whether a subject has a depressive symptom. The discriminating device includes a storage device for storing information for identifying a classifier generated by classifier generation processing based on a signal obtained by using a brain activity detecting apparatus to measure, in advance and time-sequentially, a signal indicating a brain activity of a plurality of predetermined regions of each brain of a plurality of participants in a resting state, the plurality of participants including healthy individuals and patients with depression.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: June 25, 2024
    Assignees: ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL, HIROSHIMA UNIVERSITY
    Inventors: Giuseppe Lisi, Jun Morimoto, Mitsuo Kawato, Takashi Yamada, Naho Ichikawa, Yasumasa Okamoto
  • Patent number: 12019997
    Abstract: Provided is a method of training a real-time simultaneous interpretation model based on external alignment information, the method including: receiving a bilingual corpus having a source language sentence as an input text and a target language sentence as an output text; generating alignment information corresponding to words or tokens (hereinafter, words) in the bilingual corpus; determining a second action following a first action in the simultaneous interpretation model on the basis of the alignment information to generate action sequence information; and training the simultaneous interpretation model on the basis of the bilingual corpus and the action sequence information, wherein the first action and the second action represent a read action of reading the word in the input text or a write action of outputting an intermediate interpretation result corresponding to the read action performed up to a present.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: June 25, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Young Ae Seo
  • Patent number: 12020196
    Abstract: Embodiments generate an optimized demand model for a retail item. Embodiments train a tree ensemble machine learning model comprising a plurality of trees, the training comprising storing upper bounds for each of the trees, the trees comprising levels and branches that correspond to the demand features that influence demand for the item. Embodiments generate an objective function for the demand model. At a top split of each tree, embodiments determine optimal child nodes using the stored upper bounds and calculate a new feasible region for each tree. Using bounds on the new feasible region, embodiments move down each tree to a next level of splits and generate the optimized demand model when a leaf node of every tree has been reached.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: June 25, 2024
    Assignees: Oracle International Corporation, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Leann Thayaparan, Kiran V. Panchamgam, Setareh Borjian, Georgia Perakis
  • Patent number: 12017116
    Abstract: Disclosed herein are an apparatus and method for evaluating a human motion using a mobile robot. The method may include identifying the exercise motion of a user by analyzing an image of the entire body of the user captured using a camera installed in the mobile robot, evaluating the pose of the user by comparing the standard pose of the identified exercise motion with images of the entire body of the user captured by the camera of the mobile robot from two or more target locations, and comprehensively evaluating the exercise motion of the user based on the pose evaluation information of the user from each of the two or more target locations.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: June 25, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Do-Hyung Kim, Jae-Hong Kim, Young-Woo Yoon, Jae-Yeon Lee, Min-Su Jang, Jeong-Dan Choi
  • Patent number: 12016890
    Abstract: The present invention relates to: a novel Lactobacillus intestinalis YT2 strain (deposition number: KCCM11812P); and a composition for preventing, alleviating, or treating menopause, comprising, as an active ingredient, Lactobacillus intestinalis comprising the novel strain. The present inventors have established an animal model for menopause through ovariectomy, confirmed changes of the distribution of intestinal microorganisms by the model, identified and isolated a novel Lactobacillus intestinalis strain among lactic acid bacteria of which the distribution is significantly reduced in the menopausal model, and confirmed effects, by means of the novel strain and previously reported Lactobacillus intestinalis strains, of alleviating menopausal symptoms, such as the inhibition of an increase in body fat, the inhibition of a decrease in bone mineral density, the inhibition of an increase in the pain sensitivity, and the alleviation of depression.
    Type: Grant
    Filed: April 6, 2022
    Date of Patent: June 25, 2024
    Assignee: KOREA FOOD RESEARCH INSTITUTE
    Inventors: Young-Do Nam, Yun-Tai Kim, Hee Soon Shin, So-Young Lee, Jae-Goo Kim, Eun-Yeong Lim, Eun-Ji Song
  • Patent number: 12021760
    Abstract: A routing establishing method for constructing a routing of a chain network including communication routers, each including a wired communication module, a wireless communication module, and a device configuration file. In a wired exploration procedure, exploration is performed by the source communication router through the wired communication module to obtain a wired communication status between the source and the destination communication routers. In a wireless exploration procedure, exploration is performed by the source communication router through the wireless communication module to obtain a wireless communication status between the source and the destination communication routers. In a routing decision procedure, next hop of the source communication router and whether the transmission routing is through the wired or the wireless communication module are determined and set according to the wired and the wireless communication status.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: June 25, 2024
    Assignees: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, CSBC CORPORATION, TAIWAN
    Inventor: Yu-Wen Huang
  • Patent number: 12020827
    Abstract: A nuclear reactor includes a reactor container, a reactor core, a control drum assembly, a hot channel, a heat exchanger and a main pump. The reactor container contains a coolant; the reactor core is arranged at a lower middle part of the reactor container; the control drum assembly is arranged on an outer periphery of the reactor core, and includes control drums arranged at intervals along a peripheral direction of the reactor core; the hot channel is arranged in the reactor container and located above the reactor core. The hot channel has a bottom hermetically connected to the control drum assembly and a top hermetically connected to an inner top surface of the reactor container. The hot channel has a hot pool passage for the coolant to pass through. The heat exchanger is arranged in the reactor container and located on an outer periphery of the hot channel.
    Type: Grant
    Filed: December 31, 2021
    Date of Patent: June 25, 2024
    Assignee: STATE POWER INVESTMENT CORPORATION RESEARCH INSTITUTE
    Inventors: Linsen Li, Gang Zheng, Chunyuan Liu, Mian Xing, Peidong Sun, Yeoh Eing Yee, Zhaocan Meng, Xiaosong Chen, Zhen Luo, Yilin Zhang, Shuming Zhang, Xiaosheng Li, Zhihui Li, Xiaotao Liao, Canhui Sun, Yaodong Chen, Yuquan Li
  • Patent number: 12017188
    Abstract: Described herein are mixed matrix filtration membranes and related, dendrimers, dendrimer particles, compositions, methods and systems and in particular mixed matrix filtration membranes with an embedded dendrimer particles and related compositions, methods, and systems wherein each dendrimer particle comprises at least two dendrimers each having at least two core chemical moieties having a core multiplicity Nc; branch cell units attached to the core chemical moiety or one to another, with the branch cell units attached one to another having a branch cells multiplicity Nb; and a number of surface functional groups Z presented on terminal branch cell units, wherein Z=NcNbG with G?3.
    Type: Grant
    Filed: November 11, 2021
    Date of Patent: June 25, 2024
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Mamadou S. Diallo, Madhusudhana Rao Kotte, Alex Kuvarega
  • Patent number: 12021745
    Abstract: An operation method of a boundary IAB node between a first topology and a second topology in a communication system may include: receiving, from a first IAB donor node included in the first topology, a first address of a first node included in the second topology; receiving, from a node connected to the boundary IAB node, data including a relay request using a second address as a destination address; rewriting the destination address of the data with the first address indicated by the second address in a mapping table; and routing the data towards the first node.
    Type: Grant
    Filed: August 19, 2022
    Date of Patent: June 25, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Seung Kwon Baek, Jun Hwan Lee
  • Patent number: 12017296
    Abstract: A multi-source self-adaptive low-stress additive manufacturing apparatus including a multi-axis manipulator additive manufacturing system, a high-energy sound beam regulation system, a substrate and a self-adaptive additive manufacturing workbench. The multi-axis manipulator additive manufacturing system includes multi-axis manipulator(s), welding torch(es), manipulator controller(s) and a guide rail, where base(s) of the multi-axis manipulator(s) is connected with the guide rail, the welding torch(es) is held by distal end(s) of the multi-axis manipulator(s), the multi-axis manipulator(s) is controlled by the manipulator controller(s) to move the welding torch(es) to conduct low-stress additive manufacturing on the workpiece to be additive manufactured.
    Type: Grant
    Filed: July 17, 2023
    Date of Patent: June 25, 2024
    Assignee: BEIJING INSTITUTE OF TECHNOLOGY
    Inventors: Chunguang Xu, Wenjun Zhang, Bo Yang, Wenkai Li
  • Patent number: 12018275
    Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues of organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provide dare methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: June 25, 2024
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Feng Zhang, Le Cong, Fei Ran
  • Patent number: 12022522
    Abstract: An operation method of a terminal that receives a DRS in a mobile communication system operating in an unlicensed spectrum includes: receiving an SS/PBCH block included in the DRS; checking at least one monitoring occasion for a PDCCH for receiving RMSI on the basis of a PBCH included in the SS/PBCH; monitoring the at least one monitoring occasion and detecting the PDCCH for receiving the RMSI; and receiving a PDSCH including the RMSI on the basis of the detected PDCCH, wherein the at least one monitoring occasion is set to at least one symbol among symbols in front of the PDSCH and symbols behind the PDSCH. Accordingly, the DRS and data may be reliably transmitted and received in the mobile communication system operating in the unlicensed spectrum.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: June 25, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jung Hoon Lee, Jae Heung Kim, Cheul Soon Kim, Tae Joong Kim, Sung Hyun Moon
  • Patent number: 12021563
    Abstract: A highly integrated multi-channel optical module is provided. The optical module includes an optical source device mounted on a substrate by an optical source mount unit, a waveguide mounted on the substrate by a waveguide mount unit, a lens mount unit disposed between the optical source device and the waveguide and mounted on the substrate, and a lens unit fixed to the lens mount unit by an adhesive cured by ultraviolet (UV) parallel light, wherein a light path of the UV parallel light is formed in the lens mount unit by a reflector attached on a side surface of the lens mount unit, and the UV parallel light moves along the light path and cures the adhesive coated on an upper portion of the lens mount unit facing a lower end portion of the lens unit.
    Type: Grant
    Filed: June 28, 2022
    Date of Patent: June 25, 2024
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Hae Chung Kang, Eun Kyu Kang, Jong Jin Lee, Sang Jin Kwon, Won Bae Kwon, Dae Seon Kim, Dae Woong Moon, Soo Yong Jung, Gye Sul Cho
  • Patent number: 12016385
    Abstract: The present invention relates to a loosening mechanism and an aerial fog generating device, wherein the loosening mechanism comprises a rotating portion; the rotating portion comprises an outer housing and an inner housing, the outer housing is sleeved onto the inner housing, and the inner housing is used for placing an aerial fog forming substrate; a pressing mechanism is provided on the inner housing, the outer housing is capable of moving along a circumferential direction, and the circumferential movement is converted into axial movement to drive the pressing mechanism to apply a radial pressing force to the aerial fog forming substrate; the inner housing is capable of being rotatably connected to the aerial fog generating device between a first position and a second position, and the aerial fog forming substrate and a heating element are capable of generating relative movement in the circumferential direction in the process from the first position to the second position; and the aerial fog forming substra
    Type: Grant
    Filed: November 26, 2018
    Date of Patent: June 25, 2024
    Assignees: SHANGHAI NEW TOBACCO PRODUCT RESEARCH INSTITUTE CO., LTD., SHANGHAI TOBACCO GROUP CO., LTD
    Inventors: Xianglin Li, Liuming Huang, Jiajun Wang, Jianghong Qu
  • Patent number: 12016959
    Abstract: A sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet including a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: June 25, 2024
    Assignees: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroyuki Tanaka, Kiyoshi Okada, Hideki Yoshikawa, Koji Suzuki, Mitsuhiro Ebara
  • Patent number: 12018239
    Abstract: A laser processing machine for killing specific cells from a group of cells on a surface of a layer containing an ingredient capable of absorbing laser light, the laser processing machine being configured to: control a laser light source to output laser light at 5W or less and at a wavelength of 380 nm or greater such that the laser light source is applied to a second area on a second surface of the layer opposed to the first surface; and control an actuator to provide a relative movement between the second area where the laser light is applied and the layer at a rate of 2000 mm/sec or less such that the irradiated second area absorbs energy to generate heat that kills unwanted cells on a first area of the first surface and the laser light does not instantly kill the specific cells on the first area upon irradiation.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: June 25, 2024
    Assignees: KATAOKA CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Masami Suzuki, Norio Nishi, Junichi Matsumoto, Kimio Sumaru, Toshiyuki Kanamori
  • Patent number: 12021151
    Abstract: A vertical channel thin film transistor includes substrate, lower source/drain electrode, spacer layer, upper source/drain electrode covering portion of upper surface of the spacer layer, interlayer insulating pattern covering portion of upper surface of the upper source/drain electrode and upper surface of the spacer layer exposed by the upper source/drain electrode, contact hole disposed on the lower source/drain electrode and passing through the interlayer insulating pattern, the upper source/drain electrode, and the spacer layer, active pattern covering inner wall and bottom surface of the contact hole and extending over upper surface of the upper source/drain electrode and upper surface of the interlayer insulating pattern, gate insulating pattern filling portion of the contact hole and extending along upper surface of the active pattern, and gate electrode filling portion of the contact hole and extending along upper surface of the gate insulating pattern.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: June 25, 2024
    Assignees: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Chi-Sun Hwang, SangHee Park, KwangHeum Lee, Jae-Eun Pi, SeungHee Lee, Jong-Heon Yang, Ji Hun Choi
  • Patent number: 12022748
    Abstract: A superconducting composition of matter including overlapping first and second regions. The regions comprise unit cells of a solid, the first region comprises an electrical insulator or semiconductor, and the second region comprises a metallic electrical conductor. The second region extends through the solid and a subset of said second region comprise surface metal unit cells that are adjacent to at least one unit cell from the first region. The ratio of the number of said surface metal unit cells to the total number of unit cells in the second region being at least 20 percent.
    Type: Grant
    Filed: February 1, 2023
    Date of Patent: June 25, 2024
    Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventor: Jamil Tahir-Kheli