Abstract: The present disclosure is directed to methods of screening a compound for modulating activity at a TNF-like weak inducer of apoptosis (TWEAK) binding site on a cysteine-rich domain (CRD) of fibroblast growth factor-inducible 14 (Fn14). The present disclosure also provides heterocyclic compounds and pharmaceutically acceptable salts thereof and methods for the prevention, treatment, and amelioration of cell proliferative disorders with these compounds.

Abstract: [Problem] The purpose of the present invention is to stably supply high-quality and highly uniform Wisteria floribunda agglutinin (WFA) that recognizes biologically important sugar-chain markers, to elucidate the sugar-chain recognition activity in detail, and to furthermore increase the specificity of the sugar-chain recognition activity. [Solution] The present invention involves the development of a technique for cloning genes for coding Wisteria floribunda agglutinin (WFA) and producing recombinant WFA having the same sugar-chain recognition activity as natural WFA from transformed bacteria. Natural WFA is reduced to thereby manufacture a reduced WFA monomer for specifically recognizing terminal GalNAc residue. A recombinant monomer WFA for recognizing LDN (GalNAc?1, 4GlcNAc) sugar chain, which is important as a diagnostic marker among sugar chains having a terminal GalNAc residue, is manufactured by introducing cysteine mutation to recombinant WFA or by C-terminal-side amino acid deletion.

Abstract: A system configured to provide cathodic protection to buried and/or submerged metal components and/or structures, such as pipes is disclosed. The system includes a cathodic protection apparatus having at least one upright support and a plurality of sacrificial anodes secured to the at least one upright support in a vertical orientation to provide variable cathodic protection to the metallic structures.

Abstract: Provided is a hybrid diode device. The hybrid diode device includes a first lower nitride layer disposed on a substrate and including a first 2-dimensional electron gas (2DEG) layer, a second lower nitride layer extending from the first lower nitride layer to the outside of the substrate and including a second 2DEG layer, a first upper nitride layer disposed on the first lower nitride layer, a second upper nitride layer disposed on the second lower nitride layer, a first cap layer disposed on the first upper nitride layer, a second cap layer disposed on the second upper nitride layer, a first electrode structure connected to the first lower nitride layer and the first cap layer; and a second electrode structure connected to the second lower nitride layer and the first electrode structure. The second lower nitride layer generates electric energy through dynamic movement.

Abstract: Provided is a catalyst layer for gas diffusion electrode that can be used without using carbon supports, a method for manufacturing the same, a membrane electrode assembly, and a fuel cell. The catalyst layer for gas diffusion electrode according to the present invention includes a network-like metallic catalyst formed of a sintered body, the network-like metallic catalyst including nanoparticles linked with each other to have electron conductivity; and an ion conductor, at least a part of the ion conductor contacting the network-like metallic catalyst. Further, the membrane electrode assembly according to the present invention includes a polymer electrolyte membrane provided between an anode catalyst layer and a cathode catalyst layer, and the catalyst layer for gas diffusion electrode stated above is used in at least one of the anode catalyst layer and the cathode catalyst layer.

Abstract: A data processing system having multiple executable threads is configured to generate a cross-product matrix in a single pass through data. An example system comprises memory for receiving the data, a processor having a plurality of executable threads, and software code for generating a cross-product matrix in a single pass through the data. The software code includes threaded variable levelization code for generating thread specific binary trees for classification variables, variable tree merge code for combining the thread-specific trees into overall trees for the classification variables, effect levelization code for generating sub-matrices of the cross-product matrix using the overall trees for the classification variables, and cross-product matrix generation code for generating the cross-product matrix by storing and ordering the elements of the sub-matrices in contiguous memory space.

Abstract: A method and device for increasing a resolution for each viewpoint in a glassless three-dimensional (3D) display. A method of controlling a three-dimensional (3D) display device including a display panel and a lens includes performing time-division on a plurality of viewpoint images such that each of the viewpoint images is divided into n division images, transferring the division images to the display panel by increasing n times a frame rate of the division images, and controlling the lens such that the division images transferred to the display panel pass through a lens cell.

Abstract: Isolated monoclonal antibodies which bind to Ebola virus glycoprotein and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

Abstract: A spin control electronic device operable at room temperature according to an embodiment of the present invention includes a transfer channel that includes a low-dimensional nanostructure, the nanostructure being located on a substrate, having an elongate shape in a first direction and having a cross section, cut along a second direction that is perpendicular to the first direction, in the shape of a triangle; a source electrode located on the substrate and intersecting the transfer channel, the source electrode covering part of the transfer channel; and a drain electrode spaced apart from the source electrode on the substrate, the drain electrode intersecting the transfer channel and covering part of the transfer channel.

Abstract: Disclosed is a random access method for a machine type communication (MTC) terminal. The random access method performed by a terminal includes performing a cell search, determining a radio environment based on time taken to perform the cell search, and performing different random access procedures depending on the determined radio environment. Accordingly, coverage of the MTC terminal that is in a poor radio environment may be enhanced, thereby performing normal communication with a base station.

Abstract: Standalone LTE based communication networks. Embodiments herein disclose methods and systems for providing LTE based communication to at least one User Equipment (UE) over a small region using a rapidly deployable standalone network wherein at least one LTE UE would be able to connect to an Application Server (AS).

Abstract: The present invention relates to a method for treating breast cancer in a subject having a breast cancer of the estrogen receptor (ER?) negative type, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of the Large Tumor Suppressor Kinase (LATS). Also provided are a siRNA decreasing or silencing the expression of the Large Tumor Suppressor Kinase (LATS), and an antibody specifically binding to the Large Tumor Suppressor Kinase (LATS), for use to treat breast cancer of the estrogen receptor (ER?) negative type.

Abstract: The present invention provides soluble single wall nanotube (SWNT) constructs functionalized with a plurality of a targeting moiety and a plurality of one or more payload molecules attached thereto. The targeting moiety and the payload molecules may be attached to the soluble SWNT via a DNA or other oligomer platform attached to the SWNT. These soluble SWNT constructs may comprise a radionuclide or contrast agent and as such are effective as diagnostic and therapeutic agents. Methods provided herein are to diagnosing or locating a cancer, treating a cancer, eliciting an immune response against a cancer or delivering an anticancer drug in situ via an enzymatic nanofactory using the soluble SWNT constructs.

Abstract: A system and method for detecting laser pulses is disclosed. According to one embodiment, the present system detects an extrasolar laser pulse, ideally repeated pulses, by observing the pulse, characterizing the pulse, and confirming the data related to the pulse.

Abstract: A system and method for decoding an intended transmission includes a user device that receives a downlink transmission containing a user signal intended for the user device and one or more interfering user signals directed to one or more other user devices. The user device obtains power stacking information that includes a power level for each of the user signals contained in the received downlink transmission. A channel is estimated using pilot signals in the downlink transmission. Each interfering user signal contained in the downlink transmission is demodulated and decoded using the power stacking information. The user device removes all interfering user signals from the received downlink transmission to obtain the user signal intended for the user device.

Abstract: The present invention relates to a one-way wave equation prestack depth migration method using an elastic generalized-screen (EGS) wave propagator capable of efficiently expressing the movement of an elastic wave passing through a mutual mode conversion between a P-wave and an S-wave while propagating boundary surfaces of an underground medium, by expanding, to an elastic wave equation, a conventional scalar generalized-screen (SGS) technique capable of quickly calculating the propagation of a wave in a medium in which there is a horizontal speed change, and according to the present invention, provided is a prestack EGS migration method for seismic wave multi-component data, which: can calculate a wave field with higher accuracy in a medium having a complex structure by expanding up to a second term of a Taylor series expansion of a vertical slowness term of a propagator; includes a mode separation operator in the propagator so as to directly use a shot gather as a migration input, without the need to separat

Abstract: A method of reconstructing a magnetic resonance image includes receiving echo planar imaging (EPI) data, acquiring an even scan line image and an odd scan line image from k-space data of the EPI data, and reconstructing missing portions of the even scan line image and the odd scan line image.

Abstract: The present invention provides a semiconductor device manufacturing method for lowering the technical difficulties of a process forming a horizontal single crystal nanowire and a manufacturing cost, the semiconductor device manufacturing method comprising the steps of: preparing a substrate including a first area and a second area; determining a position at which a nanowire is to be formed on the substrate of the first area and arranging an empty space in which the nanowire is to be filled; exposing a substrate surface of a part adjacent to the first area; causing selective single crystal growth from the exposed substrate surface; and forming a nanowire by a self-aligned method through an etching process within the first area, and removing, from outside the first area, a single crystal growth layer of the remaining areas excluding a part necessary for the wiring of the second area.

Abstract: According to the present invention, a deuterium-substituted marker for fuel is synthesized through substitution with deuterium so as to have structurally and chemically similar properties to those of a molecule configuring fuel oil. A molecule of the deuterium-substituted marker is significantly similar to the conventional molecule configuring the fuel oil, which may prevent illegal removal of the marker by the fake oil manufacturers. According to the present invention, it is able to pursue public safety and environmental protection from fake oil products, and to prevent national tax evasion, by preventing the illegal mixing of fuel oil to secure a legal distribution of the oil market according to the present invention.

Abstract: Systems and methods described herein incorporate autonomous navigation using a vision-based guidance system. The vision-based guidance system enables autonomous trajectory planning and motion execution by the described systems and methods without feedback or communication with external operators. The systems and methods described herein can autonomously track an object of interest while seeking to obtain a diversity of views of the object of interest to aid in object identification. The systems and methods described include a robust reacquisition methodology. By handling navigation and tracking autonomously, systems described herein can react more quickly to non-cooperative moving objects of interest and can operate in situations where communications with external operators is compromised or absent.