Abstract: Compositions and methods for the detection and treatment of cancer are provided. It has been discovered that uterine cancer cells selectively induce the survivin promoter to express a gene product. One embodiment provides a method for detecting uterine malignancy by systemic administration of a cancer-specific vector that utilizes a Survivin promoter to drive expression of a reporter gene. The expression of the reporter gene is detectable exclusively in malignant cells, for example using conventional imagining techniques.

Abstract: A method for simultaneously transmitting packets having different lengths to two or more users in a wireless communication system includes: generating the packets to transmit to the respective users, the packets containing information on the maximum transmission length of the packets having different lengths; and simultaneously transmitting the generated packets to the respective users. The maximum transmission length is represented by the number of symbols, and each of the packets sequentially contains control information required for transmitting the packet, data, a tail field, and a PHY pad field, and is generated by inserting a MAC pad between the control information and the data such that the tail field and the PHY pad field are positioned at the last byte of the last symbol of the maximum transmission length.

Abstract: A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event.

Abstract: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein X1, X2, X3, X4, X5, W1, W2, W3, and W4 are as described. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them. In one aspect, the invention relates to selective HDAC3 inhibitors useful for protecting ?-cells and improving insulin resistance. The selective HDAC3 inhibitors are also useful for promoting cognitive function and enhancing learning and memory formation.

Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems comprising a novel DNA or RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.

Abstract: Disclosed is a filter including a second layer disposed between a first layer and a third layer. The first layer is composed of iron. The second layer is composed of 1 part by volume of lithium fluoride, 20 to 50 parts by volume of aluminum, and 50 to 80 parts by volume of aluminum fluoride. The third layer is composed of 1 part by weight of lithium fluoride and 99 to 100 parts by weight of magnesium fluoride.

Abstract: The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or more protrusions extending into the channel from the substrate or the flexible membrane. The one or more protrusions define a plurality of recesses extending beyond the intersection between the channel and the flexible membrane; A microfluidic circuit including one or more sieve valves. In particular embodiments, the circuit comprises one or more input/output valves. The one or one or more input/output valves can include one or more input valves and one or more output valves. The microfluidic circuit can further include a mixing circuit. At least one of the sieve valves can be positioned between the one or more input/output valves and the mixing circuit. The invention further provides methods of using the device for the analysis of samples comprising cells.

Abstract: Systems and methods in accordance with embodiments of the invention implement bulk metallic glass-based strain wave gears and strain wave gear components. In one embodiment, a method of fabricating a strain wave gear includes: shaping a BMG-based material using a mold in conjunction with one of a thermoplastic forming technique and a casting technique; where the BMG-based material is shaped into one of: a wave generator plug, an inner race, an outer race, a rolling element, a flexspline, a flexspline without a set of gear teeth, a circular spline, a circular spline without a set of gear teeth, a set of gear teeth to be incorporated within a flexspline, and a set of gear teeth to be incorporated within a circular spline.

Abstract: A feed liquid flows into a second-stage humidifier chamber to form a second-stage humidifier bath. A first remnant of the feed liquid from the second-stage humidifier chamber then flows into a first-stage humidifier chamber to form a first-stage humidifier bath having a temperature lower than that of the second-stage bath. A second remnant of the feed liquid is then removed from the first-stage humidifier. Meanwhile, a carrier gas is injected into and bubbled through the first-stage humidifier bath, collecting a vaporizable component in vapor form from the first remnant of the feed liquid to partially humidify the carrier gas. The partially humidified carrier gas is then bubbled through the second-stage humidifier bath, where the carrier gas collects more of the vaporizable component in vapor form from the feed liquid to further humidify the carrier gas before the humidified carrier gas is removed from the second-stage humidifier chamber.

Abstract: Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities.

Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.

Abstract: A bit interleaver, a bit-interleaved coded modulation (BICM) device and a bit interleaving method are disclosed herein. The bit interleaver includes a first memory, a processor, and a second memory. The first memory stores a low-density parity check (LDPC) codeword having a length of 16200 and a code rate of 2/15. The processor generates an interleaved codeword by interleaving the LDPC codeword on a bit group basis. The size of the bit group corresponds to a parallel factor of the LDPC codeword. The second memory provides the interleaved codeword to a modulator for 64-symbol mapping.

Abstract: A package structure of an electronic device includes a first substrate, a second substrate, an electronic device and a first barrier structure. The first substrate includes a first light-transmitting portion and a periphery portion. The second substrate includes a second light-transmitting portion and two covering portions located on two sides of the second light-transmitting portion. The first light-transmitting portion is disposed corresponding to the second light-transmitting portion, and a device disposition region exists therebetween. The covering portions cover the periphery portion of the first substrate and two opposite side surfaces of the first substrate. The electronic device is disposed on the first or second substrate, and is located in the device disposition region. The first barrier structure disposed on the first substrate or the second substrate is disposed corresponding to the periphery portion and disposed on at least one side of the device disposition region.

Abstract: Provided are an encoding device using predictive coding in a screen and a method thereof, and a decoding device and a method thereof. The encoding device is capable of generating a prediction block of a current block according to one of methods for generating a plurality of predetermined prediction blocks, and outputting at least one of encoding information and differential blocks as bitstream by entropy encoding according to whether differential blocks are encoded or not.

Abstract: A central control device and a load balancing method thereof are provided. The central control device includes a network interface, a storage and a processor. The network interface is connected to a plurality of base stations and receives a load parameter from each base station. The storage stores the load parameters. The processor is electrically connected to the storage and the network interface. For each base station, the processor calculates a load indication according to the load parameter thereof to determine whether the base station is an overloaded base station based on the load indication, and calculates an offload priority indication according to the load indication, a quantity of off-loadable resources of at least one neighboring base station, a first weighting factor and a second weighting factor. The processor determines an offload order of the overloaded base stations according to the offload priority indications.

Abstract: The present invention relates to a monolith catalyst for a carbon dioxide reforming reaction and to a preparation method for same, and more specifically the invention provides a preparation method for a monolith catalyst for a methane reforming reaction using carbon dioxide, the method comprising a step of mixing and impregnating a support in a metal precursor solution, coating a monolith substrate with the solution resulting from the mixing and impregnating, drying same and then calcining the monolith substrate coated with the solution resulting from the mixing and impregnating.

Abstract: The present invention relates to a nanometal-flake graphite composite and a method of manufacturing the same, and more particularly, to a nanometal-flake graphite composite, in which nanometal-flake graphite, in which crystallized nanometal particles are highly densely bonded to the surface of flake graphite, is coated with polydopamine to form a polydopamine coating layer which significantly improves properties such as bonding properties between flake graphite basal planes, adhesiveness with other media, and dispersibility, and a method of manufacturing the nanometal-flake graphite composite.

Abstract: Provided is a display device in a mechanical method using wind, vibration. The mechanoluminescent display device includes a substrate having a predetermined shape, and projections formed with a predetermined pattern on the substrate. The projections are formed of a mixture of a stress luminescent material emitting light by mechanical energy which is applied and a stress transmission material transmitting the mechanical energy applied from the outside to the stress luminescent material.

Abstract: Provided in one embodiment is a method of identifying a stable phase of an ordering binary alloy system comprising a solute element and a solvent element, the method comprising: determining at least three thermodynamic parameters associated with grain boundary segregation, phase separation, and intermetallic compound formation of the ordering binary alloy system; and identifying the stable phase of the ordering binary alloy system based on the first thermodynamic parameter, the second thermodynamic parameter and the third thermodynamic parameter by comparing the first thermodynamic parameter, the second thermodynamic parameter and the third thermodynamic parameter with a predetermined set of respective thermodynamic parameters to identify the stable phase; wherein the stable phase is one of a stable nanocrystalline phase, a metastable nanocrystalline phase, and a non-nanocrystalline phase.

Abstract: A method and apparatus for generating frames to apply error correction to data including a plurality of consecutive data groups are provided. Upon receiving input of an n-th data group consisting of a plurality of priority groups with different priority levels, the number of first code rate frames, which is the number of frames in the n-th data group for which a first code rate is used, is calculated based on the number of first code rate bits calculated based on the ratio of the length of data in an (n?1)-th data group for which the first code rate is used. The number of second code rate frames, which is the number of frames in the n-th data group for which the second code rate is used, is calculated based on the number of second code rate bits calculated based on the number of first code rate bits. Frames for error correction are generated based on the number of first code rate frames and the number of second code rate frames.