Abstract: Compounds are provided having agonistic activity against G protein-coupled receptor 35 (GPR35). The compounds are useful for providing antinociception, providing neuroprotection in case of stroke or ischemia, or treating gastric inflammation.

Abstract: A mixed power supply device includes a power supply component for providing a DC voltage; a DC-DC conversion module coupled to the power supply component to receive the DC voltage and output a stable DC voltage; a current transformation module coupled between the DC-DC conversion module and a load to receive the stable DC voltage and convert the stable DC voltage into an AC voltage; and a merging network switching switch coupled to the current transformation module to connect the current transformation module and a utility power network in parallel or disconnect the current transformation module from the utility power network, allowing a load to receive merging network mode-based power supply or standalone mode-based power supply, wherein, in the merging network mode, the current transformation module performs unbalanced current compensation on load unbalance of the load.

Abstract: A device for color imaging including an optical sensor having light sensitive pixels with a metal film disposed over the light sensitive pixels. The metal film has a group of nano-holes arranged over the pixels according to a periodic lattice formation and is configured to pass light of a preselected first range of wavelengths. The group of nano-holes arranged over an adjoining group of pixels is configured to pass light having ranges of wavelengths different from the first range of wavelengths.

Abstract: A three-dimensional (3D) emitting apparatus includes a table on which an object is to be disposed, a robot arm to perform a task on the object, an emitting member provided at an end portion of the robot arm, and a controller to control an operation of the robot arm or a position of the emitting member, wherein the table and the robot arm may move relatively in a vertical or horizontal direction, the emitting member may move along a trajectory of rotation of the robot arm, and the trajectory of rotation may be provided in a form of a concentric sphere having a center at which a target point is disposed.

Abstract: This disclosure provides replication-incompetent adenoviral vectors useful in vaccine development and gene therapy. The disclosed vectors comprise a selective deletion of E3 and are particularly useful for preparation of vaccines development and for gene therapy using toxic transgene products that result in vector instability that occurs when the entire E3 domain is deleted.

Abstract: An apparatus for mixing a solution includes first and second tanks, a sampling element, a flow control element, a mixing assembly, first and second air-intake systems, and first and second air-exhaust systems. The first tank has a first chamber. The second tank has a second chamber. The sampling element has an extraction port located in the first chamber. The flow control element connects and communicates with the first chamber. Two opposite ends of the mixing assembly connect and communicate with the first chamber and the second chamber, respectively. The first air-intake system and the first air-exhaust system connect and communicate with the first chamber. The second air-intake system and the second air-exhaust system connect and communicate with the second chamber.

Abstract: Described herein are conduits for conveying fluids and/or solids, the conduits having an interior surface that provide a high-slip boundary condition, thereby facilitating the flow of material therethrough. In some embodiments, the conduit has an interior surface with an impregnating liquid and a plurality of micro-scale and/or nano-scale solid features spaced sufficiently close to stably contain the impregnating liquid therebetween. The impregnating liquid fills spaces between the solid features, the interior surface stably contains the impregnating liquid between the solid features, and the impregnating liquid is substantially held in place between the plurality of solid features regardless of orientation of the interior surface and regardless of flow, passage, or removal of fluids and/or solids through, into, or out of the conduit.

Abstract: A composition that includes a high-valent compound of copper, silver or indium; a linear, branched or cyclic C1-18 alcohol; and a Group VIII metal catalyst forms a metal film of copper, silver or indium on a substrate when the composition is coated on the substrate and heated to reduce the high-valent compound. The composition may alternatively include metal particles of silver, copper or indium in which the surface layer of the particle includes a high-valent compound of copper, silver or indium. A metal film of copper, silver or indium may also be formed on a substrate by coating a substrate with the composition including the metal particles, and heating to reduce the high-valent compound in the same manner as above.

Abstract: A pegylated artesunate derivative, a pharmaceutical composition and uses thereof, the pegylated artesunate derivative is represented by the general formula (I): The pegylated artesunate derivative has activity comparable to that of artesunate, increased water solubility and stability, and an extended half-life in vivo.

Abstract: This invention specifies mechanisms for detection of failure of links directly attached to communication devices (hosts and gateways) or lying in the path between these devices. The invention also specifies mechanisms for recovering communication sessions when the failure occurs. The failure in a link connected to the host or to the gateway is detected by using a link layer trigger by the respective node while the gateway failure or failure in a remote link is detected by a signaling mechanism initiated by the host on the basis of two control timers, probe timer and keepalive timer. The edge router and gateway also assist the host to detect the failure and quickly start the recovery process. They perform packet redirection through a lively link to the host, thus reducing or completely avoiding packet losses while the host performs the recovery mechanism to transfer the session from the failed link to the lively link.

Abstract: The present invention provides a capacitive acceleration sensor with a bending elastic beam and a preparation method. The sensor at least includes a first electrode structural layer, a middle structural layer and a second electrode structural layer; wherein the first electrode structural layer and the second electrode structural layer are provided with an electrode lead via-hole, respectively; the middle structural layer includes: a frame formed on a SOI silicon substrate with a double device layers, a seismic mass whose double sides are symmetrical and a bending elastic beam with one end connected to the frame and the other end connected to the seismic mass, wherein anti-overloading bumps and damping grooves are symmetrically provided on two sides of the seismic mass, and the bending elastic beams at different planes are staggered distributed and are not overlapped with each other in space.

Abstract: The determination of user perceived delay in audio and video conferencing systems/services is described. Example embodiments consistent with the present invention measure delays in audio and/or video conferencing systems and services, by treating such systems and services as black boxes, thereby providing end-to-end delays as they would be perceived by users. For example, the user perceived round-trip delay in a video conference system/service may include time delays from each of video capture, video encoding, video transmission, video decoding and video rendering.

Abstract: Methods for detection and diagnosis of Sjögren's Syndrome in a subject, determining the stage or progression of Sjögren's Syndrome in a subject, determining the effectiveness of a treatment for Sjögren's Syndrome, and selecting a subject for treatment for Sjögren's Syndrome are disclosed. The methods typically include measuring the level of one or more Sjögren's Syndrome biomarkers in a biological sample obtained from a subject. Biomarkers for Sjögren's Syndrome include, but are not limited to, GADD153 and Del-1.

Abstract: A position detection device obtains image coordinate groups representing a coordinate of a target object in each acquired image having first and second acquired image groups. The first acquired image group has acquired images obtained at an image acquiring timing in a reference period. The second acquired image group has acquired images obtained at an image acquiring timing in the reference period, which is delayed from the image acquiring timing of the first acquired image group by an asynchronous time. The device performs a Fourier transformation of each of a first locus and a second locus, and calculates a first frequency waveform based on the first locus and a second frequency waveform based on the second locus. The device calculates a position of the target object based on a relationship in which the frequency waveforms are delayed relative to each other by a phase corresponding to the asynchronous time.

Abstract: A neural probe includes at least one shaft, at least one first electrode disposed on a first side of the at least one shaft, and at least one second electrode disposed on a second side of the at least one shaft. The at least one second electrode is separately addressable from the at least first electrode.

Abstract: A geothermal power generation system using heat exchange between working gas and molten salt includes a heat collector. A plurality of molten salt containers is disposed in a heat transferor at predetermined intervals from each other. A heat exchanger transfers a heat source of the heat collector to the molten salt in the plurality of molten salt containers. The heat transferor is disposed in the ground. Working gas which receives the heat source of the molten salt via heat exchange enters and exits the heat transferor. A turbine unit is connected to the heat transferor, and generates mechanical energy using energy of the working gas. A power generating unit is connected to the turbine unit, and generates electrical energy using the mechanical energy.

Abstract: Hardware and software methodology are described for a non-invasive approach to blood pressure measurement in pulmonary artery and systemic arteries by using wall displacement and blood velocity that are measured using ultrasound, microwave techniques and/or other radiofrequency (RF) techniques.

Abstract: An unmanned vehicle system, having at least one autonomous ground vehicle (A-GV) and at least one remote controlled aerial vehicle (RC-AV). The A-GV autonomously navigates across the ground, and on-board perception sensors, whose field of view that contains at least a portion of the ground ahead of the direction of travel of the ground vehicle as well as the RC-GV. The RC-AV flies in response to commands received from the control system of the A-GV. The RC-AV has on-board in-sky perception sensors having a field of view that contains at least a portion of the ground path to be followed by the ground vehicle. The control system of the A-GV locate the aerial vehicle, receives perception data from the on-ground perception sensors and the in-sky perception sensors, and uses combined perception data to determine a ground path for itself and for the RC-AV.

Abstract: Methods and systems for operating a sensor network comprising a plurality of nodes and at least one resource, where a resource can be a sensing device (e.g., a camera or microphone) or other peripheral devices (e.g., a storage or recording system). In at least one embodiment of the present invention, at least one node in a network determines at least one resource available to it and the type of the resource or its capabilities. Based on the type or capabilities of the resource, the node associates with one or more logical node names and acquires instructions for performing at least one function.

Abstract: A method of receiving content in a client is provided. The method may include receiving, from a server, a spatial set identifier (ID) corresponding to a tile group including at least one tile, sending, to the server, a request for first content corresponding to metadata, and receiving, from the server, the first content corresponding to the request.