Abstract: An method for selective breeding of a fast-growing strain of lined seahorse, including: (1) selecting high-quality lined seahorse parents as a base population for selective breeding; (2) performing prenatal intensified breeding; (3) performing pairing and mating, and rearing the juveniles thereof; (4) performing selective breeding in three junctures with different selection proportions; (5) pairing the saved adult lined seahorses, wherein those with low vitality, having injuries on the body surface, or having a dysplastic brood pouch or gonad are culled, and a selection proportion of 10% for every generation is maintained thereafter; (6) repeating steps (2) through (5) for at least four times to obtain a high-quality strain of lined seahorse with improved weight and body length and stable growth. The method can be used for selective breeding of a new strain with high quality and high yield.
Type:
Application
Filed:
June 15, 2015
Publication date:
April 20, 2017
Applicant:
SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE A CADEMY OF SCIENCES
Abstract: Strategies to control the level of dissolved carbon dioxide (CO2) concentrations and/or pH in small volume reactor chambers, and associated articles, systems, and methods, are generally provided. In certain embodiments, the reactor chambers can be configured to contain at least one biological cell.
Type:
Application
Filed:
May 20, 2016
Publication date:
April 20, 2017
Applicants:
Massachusetts Institute of Technology, Sanofi
Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
Type:
Application
Filed:
December 21, 2016
Publication date:
April 20, 2017
Applicants:
The Board of Trustees of the University of Arkansas, The Kitasato Institute, Montefiore Medical Center
Inventors:
Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure
Abstract: The present disclosure provides a hydrogel composition including: a hydrogel having a structure represented by Formula (I) or Formula (II) shown as follows: A-B-BOX-B-A, Formula (I); B-A-B-(BOX-BAB)n-BOX-B-A-B, Formula (II), wherein, A is a hydrophilic polyethylene glycol polymer, B is a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2,2?-Bis(2-oxazoline) for coupling di-block of A-B or tri-block of B-A-B, and n is an integer greater than or equal to 0; and an anti-adhesion additive, wherein the anti-adhesion additive comprises a carbohydrate, a nitrogen-containing cyclic compound, a polymer or a combination thereof.
Type:
Application
Filed:
October 14, 2016
Publication date:
April 20, 2017
Applicant:
Industrial Technology Research Institute
Abstract: The present invention relates to a flaky graphite-based polymer nanocomplex for preparation of a polymer complex, and more specifically, to a complex to which a polymer is stably bonded by surface-modifying, with a catecholamine, flaky graphite having a structure with nanoparticles crystallized at a high density on the surface. If the complex is dispersed in a target polymeric resin, preferably, in a homogeneous polymeric resin which is bonded to the complex, the complex is dispersed in the polymeric resin homogeneously and evenly, thereby being capable of obtaining a composite having excellent function in conductivity, thermal conductivity, etc.
Type:
Application
Filed:
March 23, 2015
Publication date:
April 20, 2017
Applicant:
Cheorwon Plasma Research Institute
Inventors:
Seong-In Kim, Won Seok Choi, Won Young Lee, Young Ju Jung
Abstract: The invention is directed to a bispecific chimeric antigen receptor, comprising: (a) at least two antigen-specific targeting regions; (b) an extracellular spacer domain; (c) a transmembrane domain; (d) at least one co-stimulatory domain; and (e) an intracellular signaling domain, wherein each antigen-specific targeting region comprises an antigen-specific single chain Fv (scFv) fragment, and binds a different antigen, and wherein the bispecific chimeric antigen receptor is co-expressed with a therapeutic control. The invention also provides methods and uses of the bispecific chimeric antigen receptors.
Type:
Application
Filed:
August 10, 2016
Publication date:
April 20, 2017
Applicant:
Seattle Children's Hospital d/b/a Seattle Children's Research Institute
Abstract: Provided is an antifouling sheet having an interlayer (X) containing a (poly)silazane compound and having an antifouling layer (Y) layered on the surface of the interlayer (X), wherein the layer (Y) is formed of an antifouling layer-forming composition containing a specific tetrafunctional silane compound (A) and a specific trifunctional silane compound (B), the content of the component (B) in the antifouling layer-forming composition is 8 to 90 mol % relative to 100 mol % of the component (A). The antifouling sheet is provided with an antifouling layer having good surface state and curability, has a large slip acceleration for water droplets, thereby having excellent water repellency that makes water droplets slip off instantly, and has excellent interlayer adhesiveness.
Type:
Application
Filed:
March 26, 2015
Publication date:
April 20, 2017
Applicants:
LINTEC CORPORATION, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: This technique provides a protein film production method which can form a protein film, with denaturation of protein being prevented. The protein film production method includes mixing a protein with an aqueous solvent, to thereby form an aqueous protein solution PAS1, and treating the aqueous protein solution PAS1 with plasma generated by a plasma generator 100. The plasma generated by the plasma generator 100 has a plasma density of 1×1013 cm?3 to 1×1015 cm?3.
Type:
Application
Filed:
November 15, 2016
Publication date:
April 20, 2017
Applicants:
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KYORIN UNIVERSITY
Abstract: A method of evaluating a semiconductor device having an insulated gate formed of a metal-oxide film semiconductor. The semiconductor device has a high potential side and a low potential side, and a threshold voltage that is a minimum voltage for forming a conducting path between the high and low potential sides. The method includes determining a variation of the threshold voltage at turn-on of the semiconductor device by continuously applying an alternating current (AC) voltage to the gate of the semiconductor device, a maximum voltage of the AC voltage being equal to or higher than the threshold voltage of the semiconductor device.
Type:
Application
Filed:
August 25, 2016
Publication date:
April 20, 2017
Applicants:
FUJI ELECTRIC CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY
Abstract: The present invention provides a method for manufacturing a dopant composition-nanomaterial composite, which method makes it possible to simply and efficiently change a Seebeck coefficient value of a nanomaterial. This manufacture method of the present invention includes the steps of: (a) putting a dopant composition in contact with a nanomaterial in a solvent; (b) drying a mixture obtained in the step (a) so as to remove the solvent, the dopant composition containing a given anion and an onium ion.
Type:
Application
Filed:
February 10, 2015
Publication date:
April 20, 2017
Applicants:
NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEKISUI CHEMICAL CO., LTD.
Abstract: A gateway, system and method for multiple radio access technology service are provided. The gateway is between base stations and a core network, including a receiving module, determining module and processing module. The receiving module receives a packet from the base stations or the core network through a tunnel between the base stations and the core network. The determining module determines whether the packet has a virtual IP header. If the packet has a virtual IP header, the processing module deletes the virtual IP header and replaces it with a tunnel header to transmit the packet to the core network through the tunnel by the tunnel header. If the packet has no virtual IP header, the processing module forwards the packet to the core network through the tunnel. The disclosure enhances transmitting and processing performance of the packet when the packet is transmitted through only a single tunnel.
Type:
Application
Filed:
December 22, 2015
Publication date:
April 20, 2017
Applicant:
Industrial Technology Research Institute
Inventors:
Kuo-Wei WEN, Chien-Ming LAI, Chai-Hien GAN
Abstract: Disclosed decoding method of the intra prediction mode comprises the steps of: determining whether an intra prediction mode of a present prediction unit is the same as a first candidate intra prediction mode or as a second candidate intra prediction mode on the basis of 1-bit information; and determining, among said first candidate intra prediction mode and said second candidate intra prediction mode, which candidate intra prediction mode is the same as the intra prediction mode of said present prediction unit on the basis of additional 1-bit information, if the intra prediction mode of the present prediction unit is the same as at least either the first candidate intra prediction mode or the second candidate intra prediction mode, and decoding the intra prediction mode of the present prediction unit.
Type:
Application
Filed:
November 29, 2016
Publication date:
April 20, 2017
Applicants:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Jong Ho KIM, Hui Yong KIM, Se Yoon JEONG, Sung Chang LIM, Ha Hyun LEE, Jin Ho LEE, Suk Hee CHO, Jin Soo CHOI, Jin Woong KIM, Chie Teuk AHN, Mun Churl KIM, Bum Shik LEE
Abstract: Techniques to perform data reduction for statistical tests are described. An apparatus may comprise an evaluation component to receive a computational representation arranged to generate an approximate probability distribution for statistics of a statistical test, the computational representation to include a simulated data structure with information for estimated cumulative distribution function (CDF) curves for one or more parameter vectors of the statistical test, each parameter vector represented with a single point in a grid of points, the evaluation component to evaluate the simulated data structure to determine whether any points in the grid of points are removable from the simulated data structure with a target level of precision, and a data reduction generator to reduce the simulated data structure in accordance with the evaluation to produce a reduced simulated data structure having a smaller data storage size relative to the simulated data structure. Other embodiments are described and claimed.
Abstract: Provided are an optical device and a manufacturing method thereof. The method of manufacturing an optical device may include providing a substrate structure, and depositing an array including curved structures on the substrate structure. The curved structures may include a crystalline organic compound.
Type:
Application
Filed:
October 14, 2016
Publication date:
April 20, 2017
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
YOUNG SAM PARK, Doo-Hee CHO, JEONG IK LEE, Jonghee LEE, Seongdeok AHN, Byoung Gon YU, Nam Sung CHO
Abstract: The present invention provides methods of treatment for hematological malignancies involving synergistic combination of a JAK2 inhibitor and a glucocorticoid or a JAK2 inhibitor, thalidomide or thalidomide derivative, and a glucocorticoid. The compositions and methods provide an unexpected efficacy in the treatment for hematological disorders. The hematological disorders treated by the current invention include multiple myeloma, and may also include hematological disorders that are refractory to prior cancer treatments, or a relapsed hematologic disorder.
Type:
Application
Filed:
May 28, 2015
Publication date:
April 20, 2017
Applicant:
Institute for Myeloma & Bone Cancer Research
Abstract: An anti-hepatitis C virus E2 protein antibody or antigen-binding antibody fragment thereof has infection inhibiting activity against hepatitis C virus (HCV). An anti-hepatitis C virus E2 protein antibody or antigen-binding antibody fragment thereof includes a certain variable region, which have infection inhibiting activity against hepatitis C virus (HCV) and exhibits an escape mutant emergence suppressive property.
Type:
Application
Filed:
March 20, 2015
Publication date:
April 20, 2017
Applicant:
Japan as Represented by Director-General of National Institute of Infectious Diseases
Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.
Type:
Application
Filed:
December 27, 2016
Publication date:
April 20, 2017
Applicants:
Pacific Edge Limited, Ludwig Institute for Cancer Research
Inventors:
Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
Abstract: A data device includes a memory having a plurality of memory cells configured to store data values in accordance with a predetermined rank modulation scheme that is optional and a memory controller that receives a current error count from an error decoder of the data device for one or more data operations of the flash memory device and selects an operating mode for data scrubbing in accordance with the received error count and a program cycles count.
Abstract: In a front surface of a semiconductor base body, a gate trench is disposed penetrating an n+-type source region and a p-type base region to a second n-type drift region. In the second n-type drift region, a p-type semiconductor region is selectively disposed. Between adjacent gate trenches, a contact trench is disposed penetrating the n+-type source region and the p-type base region, and going through the second n-type drift region to the p-type semiconductor region. A source electrode embedded in the contact trench contacts the p-type semiconductor region at a bottom portion and corner portion of the contact trench, and forms a Schottky junction with the second n-type drift region at a side wall of the contact trench.
Type:
Application
Filed:
August 31, 2016
Publication date:
April 20, 2017
Applicants:
FUJI ELECTRIC CO., LTD., NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY