Abstract: Methods and kits are provided for determining of immunoglobulin isotypes and subclasses in a subject. In general the subject is a human who is a transplant candidate recipient or recipient, has allergies, or has an autoimmune disease. The method involves analyzing a sample of a body fluid of a transplant candidate or recipient, allergy patient or autoimmune disease sufferer and correlating the relative amounts of each immunoglobulin isotype and subtype, such that the distribution of isotypes and subtypes is an indication of success of the transplant in the candidate and recipient or the prognosis of the autoimmune disease.
Type:
Grant
Filed:
April 7, 2010
Date of Patent:
December 27, 2016
Assignee:
NATIONAL INSTITUTE OF TRANSPLANTATION FOUNDATION
Inventors:
James C. Cicciarelli, Noriyuki Kasahara
Abstract: A segmented inverting cover plate apparatus for an underfloor vehicle lifting jack comprises a cover plate comprising a first movable cover plate (4) and a second movable cover plate (6), wherein the first movable cover plate (4) and the second movable cover plate (6) are pivotly connected via a pin shaft (15). An anti-inversion block (5) is provided directly below the pin shaft (15). A guide wheel (7) is provided below the end of the second movable cover plate (6) away from the first movable cover plate (4). An inverting arm (3) is provided below the first movable cover plate (4), with one end of the inverting arm (3) connected to the anti-inversion block (5) via a bearing (13), the other end of the inverting arm connected to a powered push rod (1) via a pin shaft (17) and an oil-containing bearing (18), and the powered push rod (1) is installed on a powered push rod mounting seat (2).
Type:
Grant
Filed:
August 28, 2015
Date of Patent:
December 27, 2016
Assignee:
CRRC QINGDAO SIFANG ROLLING STOCK RESEARCH INSTITUTE CO., LTD.
Inventors:
Hui Ding, Xiaodong Xing, Lipeng Shao, Minghai Wang
Abstract: The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.
Type:
Grant
Filed:
March 22, 2012
Date of Patent:
December 27, 2016
Assignees:
LES LABORATOIRES SERVIER, SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
Abstract: Provided is a method of manufacturing an organic light-emitting device including a graphene layer. The method of manufacturing an organic light-emitting device according to the present invention may include providing a graphene donor unit including a patterned graphene layer, providing a device unit, and attaching the graphene layer of the graphene donor unit to an organic part. The device unit may include a substrate, a lower electrode, and the organic part which are sequentially stacked, and the organic part may include a dopant. The graphene donor unit may include the graphene layer, a release layer, and an elastic stamp layer which are sequentially stacked.
Type:
Grant
Filed:
August 1, 2014
Date of Patent:
December 27, 2016
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Jong Tae Lim, Jeong Ik Lee, Hye Yong Chu, Joon Tae Ahn, Jonghee Lee, Jun-Han Han, Ji-Young Oh, Byoung Gon Yu, Jaehyun Moon, Nam Sung Cho
Abstract: Three-dimensional patterning methods of a three-dimensional microstructure, such as a semiconductor wire array, are described, in conjunction with etching and/or deposition steps to pattern the three-dimensional microstructure.
Type:
Grant
Filed:
November 30, 2010
Date of Patent:
December 27, 2016
Assignee:
The California Institute of Technology
Inventors:
Morgan C. Putnam, Michael D. Kelzenberg, Harry A. Atwater, Shannon W. Boettcher, Nathan S. Lewis, Joshua M. Spurgeon, Daniel B. Turner-Evans, Emily L. Warren
Abstract: A flow energy harvesting device having a harvester pipe includes a flow inlet that receives flow from a primary pipe, a flow outlet that returns the flow into the primary pipe, and a flow diverter within the harvester pipe having an inlet section coupled to the flow inlet, a flow constriction section coupled to the inlet section and positioned at a midpoint of the harvester pipe and having a spline shape with a substantially reduced flow opening size at a constriction point along the spline shape, and an outlet section coupled to the constriction section. The harvester pipe may further include a piezoelectric structure extending from the inlet section through the constriction section and point such that the fluid flow past the constriction point results in oscillatory pressure amplitude inducing vibrations in the piezoelectric structure sufficient to cause a direct piezoelectric effect and to generate electrical power for harvesting.
Type:
Grant
Filed:
April 24, 2014
Date of Patent:
December 27, 2016
Assignees:
CALIFORNIA INSTITUTE OF TECHNOLOGY, CHEVRON U.S.A. INC.
Inventors:
Stewart Sherrit, Phillip E. Walkemeyer, Jeffrey L. Hall, Hyeong Jae Lee, Tim Colonius, Phillipe Tosi, Namhyo Kim, Kai Sun, Thomas Gary Corbett, Alvaro Jose Arrazola
Abstract: A computer-based real-time streaming system under packet erasures wherein created messages can be decoded within a fixed delay form their creation is presented. Various code construction methods and corresponding hardware implementation for different cases of erasure link models are also presented.
Type:
Grant
Filed:
November 14, 2013
Date of Patent:
December 27, 2016
Assignee:
CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventors:
Derek Leong, Asma Qureshi, Yunkai Wei, Tracey C Ho
Abstract: A software defined network (SDN) and a corresponding mobility management method and a corresponding controller are provided. The SDN includes a controller, a plurality of switches and a plurality of edge devices. The controller manages a topology and routing actions of the SDN. When a user equipment (UE) attaches to a target edge device in the edge devices, the target edge device transmits a notification message to the controller. The controller updates flow entries in the switches and the edge devices according to the notification message.
Type:
Grant
Filed:
November 28, 2014
Date of Patent:
December 27, 2016
Assignee:
Industrial Technology Research Institute
Inventors:
Kuei-Li Huang, Chai-Hien Gan, Chia-Lung Liu
Abstract: Provided is a hidden node detection method and apparatus in a wireless communication system, the apparatus including a sensing unit to sense a first communication device transmitting a data signal from among a plurality of communication devices sharing a wireless channel, a transmitter to generate a reception notification signal in response to the sensing, and transmit the reception notification signal to the a plurality of communication devices through a band identical to a transmission band of the data signal, and a controller to prevent a collision with the data signal transmitted from the first communication device through the wireless channel by delaying processing of a data transmission request when the data transmission request is input from a second communication device among the plurality of communication devices while maintaining the transmitting of the reception notification signal.
Type:
Grant
Filed:
August 15, 2014
Date of Patent:
December 27, 2016
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Sung Jin Yoo, Jin Suk Pak, Byung Jang Jeong, Sung Hyun Hwang
Abstract: Disclosed are a graphene-ceramic hybrid coating layer formed from a graphene-ceramic hybrid sol solution including graphene (RGO: reduced graphene oxide) and a ceramic sol, wherein the graphene content in the graphene-ceramic hybrid coating layer is about 0.001 wt % to about 1.8 wt % based on the total weight of the graphene-ceramic hybrid coating layer, and a method for preparing the same.
Type:
Grant
Filed:
December 30, 2013
Date of Patent:
December 27, 2016
Assignees:
Hyundai Motor Company, Korea Institute of Ceramic Engineering and Technology
Inventors:
Kwang Il Chang, Chul Kyu Song, Dha Hae Kim, Seung Hun Hur
Abstract: The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or a combination of two or more, hCMV gene UL products. The invention also relates to immortalized B cells that produce, and to epitopes that bind to, such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies, antibody fragments, and epitopes in screening methods as well as in the diagnosis, prevention, and therapy of disease.
Abstract: A catalyst for methanation of carbon dioxide, a method of preparing the catalyst, and a method of hydrogenating carbon dioxide in the presence of the catalyst in a fixed bed reactor are disclosed. The catalyst is formed by mixing ash from a biomass power plant with a nickel compound and calcining the resulting mixture. The catalyst formed by calcination includes between 2 and 20 wt. % of nickel supported on ash from combusting biomass.
Type:
Grant
Filed:
June 30, 2016
Date of Patent:
December 27, 2016
Assignee:
WUHAN KAIDI ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
Abstract: Electrodes for use in neural stimulation applications, shaped to have fractal or pseudo-fractal geometries, with a generally planar core portion of the electrode using a base fractal geometry. A series of successively smaller holes is provided in the core portion, where each hole in the generally planar core portion can have a perimeter shape that is self-similar to a perimeter shape of the generally planar core portion. The selected electrode geometry affects the spatial distribution of the electric field in neuron-bearing tissue. This spatial distribution is related to the irregularity—or non-uniformity—of current density on the electrode surface. Optimized electrode geometries increase the efficiency of neural stimulation by maximizing the spatial variation of current density on the electrode surface.
Abstract: Stimulation of the central nervous system can be useful for treating neurological disorders. Wireless neurostimulating devices have the benefit that they can float in tissue and do not experience the sheering caused by tethering tension that connecting wires impose on the stimulators. An optically powered, logic controlled, CMOS microdevice that can decode telemetry data from an optical packet is a way of implementing wireless, addressable, microstimulators. Through the use of an optical packet, different devices can be addressed for stimulation, allowing spatially selective activation of neural tissue. The present invention, involves such a neural stimulation device, specifically an optically powered CMOS circuit that decodes telemetry data and determines whether it has been addressed.
Type:
Grant
Filed:
April 26, 2013
Date of Patent:
December 27, 2016
Assignee:
New Jersey Institute of Technology
Inventors:
Mesut Sahin, Selim Unlu, David S Freedman, Ammar R Abdo
Abstract: An imaging system on an aerial vehicle, includes: a group of rotating camera including at least a first and a second rotating cameras on the aerial vehicle; and a control part which controls a first virtual rotation track of the first rotating camera and a second virtual rotation track of the second rotating camera and allows shots to be taken at multiple photograph-shooting points on the first virtual rotation track and the second virtual rotation track; wherein the control part controls a set of multiple photograph-shooting points on the first virtual rotation track and those on the second virtual rotation track to be substantially in a grid shape. Accordingly, a 3D image could be acquired by using the group of rotating cameras on the aerial vehicle during a relatively short endurance flight and more information on images created in such a method could be estimated.
Type:
Grant
Filed:
January 6, 2016
Date of Patent:
December 27, 2016
Assignee:
National Institute of Meteorological Research
Inventors:
Kyu Young Choi, Yong Hee Lee, Kwang Deuk Ahn, Hee Choon Lee
Abstract: An inter-prediction method according to the present invention comprises the steps of: deriving motion information of a current block; and generating a prediction block for the current block on the basis of the derived motion information. According to the present invention, computational complexity can be reduced and encoding efficiency can be improved.
Type:
Grant
Filed:
June 20, 2012
Date of Patent:
December 27, 2016
Assignees:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
Inventors:
Hui Yong Kim, Gwang Hoon Park, Kyung Yong Kim, Sung Chang Lim, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim
Abstract: A node processor and method for performing matrix operations includes storing, in memory, non-zero matrix elements of a first sparse matrix, non-zero matrix elements of a second sparse matrix, and matrix elements of a sparse results matrix mapped to the node processor. A matrix communications module exchanges with other node processors, non-zero matrix elements of one or more of the first sparse matrix, second sparse matrix, and sparse results matrix. An arithmetic logic unit generates partial results based on the non-zero matrix elements of the first sparse matrix and on the non-zero matrix elements of the second sparse matrix stored in memory. The arithmetic logic unit further generates a final value for each matrix element of the sparse results matrix mapped to the node processor based on the partial results generated by the arithmetic logic unit and on partial results received from the other node processors.
Abstract: One embodiment of the present invention relates to a method for manufacturing solar cells having a nano-micro composite structure on a silicon substrate and solar cells manufactured thereby. The technical problem to be solved is to provide a method for manufacturing solar cells and solar cells manufactured thereby, the method being capable of forming micro wires in various sizes according to the lithographic design of a photoresist and forming nano wires, which have various sizes and aspect ratios, by adjusting the concentration of a wet etching solution and immersion time.
Type:
Grant
Filed:
December 18, 2012
Date of Patent:
December 27, 2016
Assignee:
KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY
Inventors:
Chae Hwan Jeong, Jong Hwan Lee, Chang Heon Kim, Ho Sung Kim
Abstract: Methods of delivering therapeutic agents by administering compositions including a bacterial collagen-binding polypeptide segment linked to the therapeutic agent to subjects in need of treatment with the therapeutic agent are provided. Methods of treating hyperparathyroidism, and hair loss using compositions comprising a collagen binding polypeptide and a PTH/PTHrP receptor agonist are provided. In addition, methods of reducing hair regrowth by administering a composition including a collagen binding polypeptide and a PTH/PTHrP receptor antagonist are provided.
Type:
Grant
Filed:
February 11, 2013
Date of Patent:
December 27, 2016
Assignees:
The Kitasato Institute
Inventors:
Tulasi Ponnapakkam, Sagaya Theresa Leena Philominathan, Joshua Sakon, Ranjitha Katikaneni, Takaki Koide, Osamu Matsushita, Robert C. Gensure
Abstract: Various embodiments include a system having interfaces, storage devices, memory, and processing circuitry. The system may be coupled with one or more storage devices and may receive episode information for a patient from a storage device via one or more wired or wireless links, the episode information includes a plurality of episodes associated with the patient, each of the plurality of episodes is a specific instance of a medical condition. The system may generate a candidate episode pairs list comprising a plurality of candidate episode pairs. Embodiments may also include the system generating a transition list comprising episode pairs from the plurality of candidate episode pairs in the candidate episode pairs list and determining attribute relationships between the plurality of episodes for the patient based on episode pairs in the transition list, the attribute relationships used to attribute items between the plurality of episodes.