Patents Assigned to INSTITUTE
  • Patent number: 9530205
    Abstract: A polyp detection apparatus and a method of operating the same are provided. The method of operating a polyp detection apparatus includes: generating an image of an object; detecting a polyp candidate region based on the generated image; detecting a reflected light region within the detected polyp candidate region; and displaying a final polyp region by excluding the detected reflected light region from the polyp candidate region.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: December 27, 2016
    Assignees: SAMSUNG ELECTRONICS CO., LTD., GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sung-hyun Kim, Kuk-jin Yoon, Seung-hwan Bae, Yeong-jun Jo, Tae-kyung Kim, Ji-woon Jung
  • Patent number: 9526800
    Abstract: Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with various aspects of cancer. Panels or signature sets of proteins useful in the detection, diagnosis and treatment of cancers as well as monitoring therapeutic progress in a cancer patient are provided herein along with methods for their detection and for their use in targeting imaging and/or therapeutic agents to the tumors via binding to the specified proteins. The proteins were identified using proteomics analyzes of tissue samples taken from cancer patients. In certain aspects the proteins are particularly useful in colon cancer patients.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 27, 2016
    Assignees: Massachusetts Institute of Technology, The General Hospital Corporation, The Broad Institute, Inc.
    Inventors: Richard O. Hynes, Alexandra Naba, Karl Clauser, Steven A. Carr, Kenneth Tanabe
  • Patent number: 9527750
    Abstract: Hollow nanoparticles having an average particle size of 30 to 300 nm and each including a shell mainly including calcium silicate.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: December 27, 2016
    Assignee: NAGOYA INSTITUTE OF TECHNOLOGY
    Inventors: Masayoshi Fuji, Takashi Shirai, Raymond V. Rivera Virtudazo, Chika Takai
  • Patent number: 9532304
    Abstract: A method for post-authenticating user equipment (UE), a controller and a network system are disclosed. The method includes: determining whether an external channel quality of at least one gateway is higher than a threshold when UE connects to an access point (AP) routed by the gateway; when the external channel quality is not higher than the threshold, authenticating the UE incompletely and controlling the AP to limit a network capability providing to the UE; estimating a future channel capacity of the gateway; calculating a priority weight of each UE; selecting candidate UE from the UEs according to the future channel capacity and the priority weight of each UE; arranging an authenticating mechanism for completely authenticating the candidate UE at a timing point corresponding to the future channel capacity.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: December 27, 2016
    Assignees: Industrial Technology Research Institute, National Chiao Tung University
    Inventors: Jyh-Cheng Chen, Jen-Shun Yang, Yi-Hao Lin, Shang-Chun Ou
  • Patent number: 9528145
    Abstract: Hydrogel microparticles spatially and spectrally encoded using upconverting phosphor nanoparticles are described for use in biochemical testing. In each microparticle, upconversion nanocrystals having spectrally distinguishable emission spectra are disposed in different pardons of an encoding region of the microparticle.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 27, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Paul Bisso, Albert Swiston, Jiseok Lee, Patrick S. Doyle
  • Patent number: 9528982
    Abstract: Despite initial sensitivity BAD-protein phosphorylation were evaluated in patient samples and cell lines as determinants of chemo-sensitivity and/or clinical outcome, and as therapeutic targets. Induced in-vitro OVCA cisplatin-resistance was associated with BAD-pathway expression. Expression of the pathway was also associated with resistance of 7 different cancers cell-types to 8 chemotherapeutic agents. Phosphorylation of the BAD-protein was associated with platinum-resistance in OVCA cells and primary OVCA specimens, and also overall patient survival. Targeted modulation of BAD-phosphorylation levels influenced cisplatin-sensitivity. A 47-gene BAD-pathway signature was associated in-vitro phospho-BAD levels and with survival of 838 patients with ovarian, breast, colon, and brain cancer. The survival advantage associated with both BAD-phosphorylation and also the BAD-pathway signature was independent of surgical cytoreductive status.
    Type: Grant
    Filed: August 26, 2013
    Date of Patent: December 27, 2016
    Assignee: H. Lee Moffitt Cancer Center and Research Institute, Inc.
    Inventors: Johnathan Lancaster, Douglas Marchion, Dung-Tsa Chen
  • Patent number: 9529012
    Abstract: A micro-electro mechanical apparatus with interdigitated spring including a substrate, at least one first mass, a movable electrode, a stationary electrode, an anchor and an interdigitated spring is provided. The movable electrode is disposed on the mass along an axial direction. The stationary electrode is disposed on the substrate along the axial direction, and the movable electrode and the stationary electrode have a critical gap there between. The interdigitated springs connects the mass and the anchor along the axial direction. The interdigitated spring includes first folded portions, first connecting portions, second folded portions, and second connecting portions. Each first folded portion includes two first spans and a first head portion. Each second folded portion includes two second spans and a second head portion. A width of the first span and a width of the second span are greater than the critical gap respectively.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: December 27, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Shih-Chieh Lin, Chao-Ta Huang, Chung-Yuan Su, Yu-Wen Hsu
  • Patent number: 9530403
    Abstract: Provided are a terminal and server of a speaker-adaptation speech-recognition system and a method for operating the system.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: December 27, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventor: Dong Hyun Kim
  • Patent number: 9527823
    Abstract: The invention provides hydroxybupropion analogs capable of inhibiting the reuptake of one or more monoamines and/or acting as antagonists at nicotinic acetylcholine receptors. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine, and serotonin and/or may selectively bind to one or more nicotinic acetylcholine receptor subtypes. Such compounds may be used to treat conditions that are responsive to modification of monoamine levels and/or antagonism of nicotinic acetylcholine receptors, including drug dependency, depression, and obesity.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: December 27, 2016
    Assignees: Research Triangle Institute, Dignity Health, Virginia Commonwealth University
    Inventors: Frank Ivy Carroll, Bruce E. Blough, Hernan A. Navarro, S. Wayne Mascarella, Ana Zamfira Muresan, M. Imad Damaj, Ronald J. Lukas
  • Patent number: 9532306
    Abstract: A method for Internet Protocol (IP)-based sleep mode control is disclosed. The method includes, when a request for a sleep mode is made from any one of internal hosts, transmitting a sleep mode request message to an internal router, updating the state of the corresponding host to a sleep mode, transmitting a sleep mode ACK message to the internal host requiring a sleep mode, switching to a sleep mode, and transmitting information about the internal hosts in a sleep mode to the external hosts of a history information list because the internal router stores the history information of the external hosts that communicated with the internal hosts in a sleep mode in the form of a list.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: December 27, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Yonggeun Hong, Myungki Shin, Hyoungjun Kim
  • Patent number: 9532441
    Abstract: A board assembly for transmitting a high-speed signal and a method of manufacturing the same. The board assembly may include a submount board, a base board, and a contact member for a signal line. The submount board may include at least one first high-speed signal line formed on the surface thereof. The base board may include the submount board on one part of the upper surface thereof, and at least second high-speed signal line on the other part of the upper surface thereof, wherein the second high-speed signal lines corresponds to the first high-speed signal lines, respectively. The contact member for the signal line may be installed on the side of the submount board, and have an upper portion contacting the first high-speed signal line and a lower portion contacting the second high-speed signal line such that the first high-speed signal line contacts the second high-speed signal line.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: December 27, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Jyung Chan Lee, Eun Gu Lee, Sil Gu Mun, Sang Soo Lee
  • Patent number: 9528817
    Abstract: Preferred embodiments of the present invention are directed to systems for phase measurement of biological materials which can be applied to the fields of, for example, cellular physiology and neuroscience. These preferred embodiments are based on principles of phase measurements and imaging technologies. The scientific motivation for using phase measurements and imaging technologies is derived from, for example, cellular biology at the sub-micron level which can include, without limitation, imaging origins of dysplasia, cellular communication, neuronal transmission and implementation of the genetic code. The structure and dynamics of sub-cellular constituents cannot be currently studied in their native state using the existing methods and technologies including, for example, x-ray and neutron scattering.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: December 27, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Christopher Fang-Yen, Gabriel Popescu, Changhuei Yang, Adam Wax, Ramachandra Dasari, Michael Feld
  • Patent number: 9526580
    Abstract: A sterile surgical tray includes structure for receiving a plurality of surgical instruments. The sterile surgical tray also may include electrical input and output connectors attached to tray.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: December 27, 2016
    Assignee: Doheny Eye Institute
    Inventors: Mark Humayun, Charles DeBoer, Matthew McCormick, Prashant Bhadri, Joel Cicchella, Ralph Kerns
  • Patent number: 9530861
    Abstract: The present invention discloses a method for manufacturing a semiconductor device, comprising the steps of: forming a dummy gate stack structure on a substrate, wherein the dummy gate stack structure contains carbon-based materials; forming source/drain region in the substrate on both sides of the dummy gate stack structure; performing etching to remove the dummy gate stack structure until the substrate is exposed, resulting in a gate trench; and forming a gate stack structure in the gate trench. In accordance with the method for manufacturing a semiconductor device of the present invention, the dummy gate made of carbon-based materials is used to substitute the dummy gate made of silicon-based materials, then no oxide liner and/or etch blocking layer needs be added while the dummy gate is removed by etching in the gate last process, thus the reliability of device is ensured while the process is simplified and the cost is reduced.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: December 27, 2016
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Haizhou Yin, Keke Zhang
  • Patent number: 9527862
    Abstract: Disclosed are aromatic spiroketal diphosphine ligands, preparation methods and uses thereof. The ligands have the structure of formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, X and n are defined as such described in the specification. The aromatic spiroketal diphosphine ligands are prepared from aromatic spiroketal compounds. Also disclosed are the preparation methods of aromatic spiroketal compounds. The preparation methods are simple and can produce racemic or chiral aromatic spiroketal diphosphine ligands.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: December 27, 2016
    Assignee: SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Kuiling Ding, Xiaoming Wang, Zhaobin Han, Xubin Wang, Zheng Wang
  • Patent number: 9527955
    Abstract: This invention provides a novel method for producing a lactide-lactone copolymer. The method is characterized by copolymerizing a lactide and a lactone using a molybdenum compound as a catalyst.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: December 27, 2016
    Assignee: NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY
    Inventors: Atsushi Abiko, Yasumi Maruta
  • Patent number: 9526582
    Abstract: An endoscope robot inserted into a duct to perform a predetermined work includes a flexible first tube body, a joint structure coupled to an end of the first tube body, and an end-effector connected to the joint structure so that location and direction of the end-effector are adjusted by the joint structure. The joint structure includes a fixed arm coupled to an end of the first tube body, and a plurality of pivotal arms arranged in order in a row from the fixed arm and pivotally connected to each other. The first tube body curves and linearly moves in the duct to move the end-effector to a working position. The plurality of pivotal arms is pivoted at the working position to adjust location and direction of the end-effector.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: December 27, 2016
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Keri Kim, Sung Chul Kang, Woosub Lee, Sangmyung Kim, Soojun Lee
  • Patent number: 9529837
    Abstract: This disclosure describes methods, systems, computer-readable media, and apparatuses for calculating a summary statistic. Calculating the summary statistic can be performed by identifying multiple subsets of a set of variable observations and assigning the subsets to grid-computing devices such that no two of the subsets are assigned to a same one of the grid-computing devices. A parallel processing operation that involves multiple processing phases at each of the grid-computing devices is then coordinated. The parallel processing operation includes each of the grid-computing devices inventorying the respectively assigned subset and generating inventory information representative of the respectively assigned subset. Subsequently, the inventory information generated by the grid-computing devices is received, and a summary statistic is determined by synthesizing the received inventory information.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: December 27, 2016
    Assignee: SAS Institute Inc.
    Inventor: Gang Meng
  • Patent number: 9526720
    Abstract: The present invention relates to compounds that are useful for modulating hepatic cholesterol metabolism in an animal. The invention includes methods of making and using the compounds of the invention. The invention further provides methods of treating, preventing and/or alleviating a cholesterol related disorder, a cardiovascular disease and/or liver disease in an animal, such as a human, comprising administering compounds of the invention, or pharmaceutically acceptable salts or solvates thereof, to the animal.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: December 27, 2016
    Assignee: The Broad Institute, Inc.
    Inventors: Marek Maria Nagiec, Jose R. Perez, Michelle Palmer, Adam Skepner, Eamon Comer
  • Patent number: 9527275
    Abstract: Large area inkjet printing includes the precise deposition of a number of graphic swathes on complex surface to form a continuous graphic image. Each of the graphic swathes should be aligned such that no spaces, gaps, or discontinuities exist within the final graphic image. A large area inkjet printing system provides the requisite accuracy for each graphic swathe forming the final graphic image through the use of an encoder pattern. An encoder pattern is deposited on the surface in a known location with respect to the most recently deposited graphic swathe. The high-accuracy inkjet printing system locates the print head with respect to the encoder pattern thereby permitting the precise positioning of the current graphic swathe.
    Type: Grant
    Filed: February 16, 2016
    Date of Patent: December 27, 2016
    Assignee: SOUTHWEST RESEARCH INSTITUTE
    Inventors: William C. Flannigan, Glynn R. Bartlett, Cody E. Bressler