Abstract: A filtration device including a contoured support having 1) an interior surface, 2) an outside peripheral surface spaced farther from a center of the contoured support than the interior surface, and 3) a rim enclosed and sealed to a perimeter of the contoured support. The filtration device includes macroscopic openings in the contoured support extending from the interior surface to the outside peripheral surface, and a plurality of nanofibers having diameters less than 1 micron. The nanofibers are disposed on the outside peripheral surface of the contoured support, and cover the macroscopic openings to form a filtration medium on the contoured support.

Abstract: The present invention provides passive safety equipment, comprising: a cooling part formed to cool a first fluid, which is emitted from a reactor coolant system or a steam generator, and a second fluid in a housing; and a circulation induction sprayer which is formed to spray the first fluid emitted from the reactor coolant system or the steam generator into the cooling part, has at least part thereof open to the inside of the housing such that the second fluid flows thereinto according to a drop in pressure caused by the spraying of the first fluid, and sprays the second fluid with the inflown first fluid.

Abstract: A BPF connected to a pulse wave generator has a bandwidth encompassing the fluctuation range of the resonance frequency of a helical antenna. As a result, even if the resonance frequency of the helical antenna fluctuates by a human body approaching the helical antenna, one or a number of a plurality of frequencies of signals passing through the BPF can pass through the bandwidth of the helical antenna.

Abstract: An optomechanical device with mechanical elements and optical filters for actuating and/or detecting movement of the elements, including a support, and on the support: an array of mechanical elements anchored to the support and configured to move with respect thereto, and an actuating and/or detection device actuating the elements and/or detecting movement of the elements or frequency variations of the movement. The actuating and/or detection device includes an array of optical filters. Each filter resonates at a particular wavelength and is coupled to one of the elements. The actuating and/or detecting device is positioned in vicinity of all or some of the elements, between the elements and the support. The optical filters are fixed with respect to the support and the mechanical elements and the optical filters are superimposed.

Abstract: A tumor antigen that comprises, as an active ingredient, a product of the Wilms' tumor suppressor gene WT1 or a peptide composed of 7-30 contiguous amino acids containing an anchor amino acid for binding to major histocompatibility complex (MHC) class I in said amino acid sequence, and a vaccine comprising said antigen.

Abstract: A system for machine training can comprise one or more data processors and a non-transitory computer-readable storage medium containing instructions which, when executed on the one or more data processors, cause the one or more data processors to perform operations including: accessing a dataset comprising data tracking a plurality of features; determining a series of values for a regularization parameter of a sparse support vector machine model, the series including an initial regularization value and a next regularization value; computing an initial solution to the sparse support vector machine model for the initial regularization value; identifying, using the initial solution, inactive features of the sparse support vector machine model for the next regularization value; and computing a next solution to the sparse support vector machine model for the next regularization value, wherein computing the next solution includes excluding the inactive features.

Abstract: Provided is a color changeable device which includes a first substrate and a second substrate that are spaced apart from each other, a first transparent electrode disposed on the first substrate, a second transparent electrode disposed on the second substrate, an electrochromic layer disposed between the first transparent electrode and the second transparent electrode, an organic layer disposed between the first transparent electrode and the electrochromic layer. The organic layer may include a hole injection layer or an electron injection layer. The organic layer may further include a hole transport layer or an electron transport layer.

Abstract: A module structure is provided, which includes a front sheet, a back sheet opposite the front sheet, and a solar cell disposed between the front sheet and the back sheet. A first encapsulate film is disposed between the solar cell and the front sheet, and a second encapsulate film disposed between the solar cell and the back sheet. One or both of the front sheet and the second sheet includes a support layer and a light conversion layer on the support layer, wherein the light conversion layer includes a fluorescent molecule and hydrogenated styrene elastomer resin. The light conversion layer is disposed between the support layer and the solar cell.

Abstract: HIV-1's ability to enter a transcriptionally dormant state and establish a reservoir of latently infected cells is considered the major barrier to eradicating the virus from infected patients. Stochastic noise (i.e. fluctuations) in an HIV-1 transcriptional positive-feedback loop is one mechanism that enables HIV-1 to establish latency. Here, Applicants demonstrate that small-molecule modulation of noise in HIV-1 gene expression radically perturbs HIV-1 latency.

Abstract: Population-Hastened Assembly Genetic Engineering is a method for continuous genome recoding using a mixed population of cells. Nucleic acid donors are distributed amongst a population of cells that continuously transfer nucleic acids to achieve asynchronous recoding of genetic information within a subpopulation of the cells. Recombination is achieved with biochemical systems compatible with virtually any organism. An engineered directed endonuclease comprises a nucleic acid recognition domain, a nucleic acid endonuclease domain, and a linker fusing or causing interaction between the nucleic acid recognition domain and the nucleic acid endonuclease domain. The method includes causing at least one engineered directed endonuclease to create a nick in a nucleic acid strand, the nick being offset from the recognition sequence of the nucleic acid recognition domain; causing homologous recombination of the strand with a donor nucleotide to create a modified genome; and replicating the modified genome.

Abstract: Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to imidazole, thiazole, and furan derivatives and their use as therapeutic agents.

Abstract: Provided is a stretchable supercapacitor and a method of manufacturing the same. The stretchable supercapacitor includes a separator between first and second current collectors. The first and second current collectors each including an active material. The second current collector is on the first current collector. The separator includes an electrolyte. Each of the separator, the first current collector and the second current collector includes an elastic polymer layer. The first and second current collectors may each have a 3-dimensional nano-pore structure. The stretchable supercapacitor may further include a first electrode in contact with the first current collector and a second electrode in contact with the second current collector. The elastic polymer layers may include at least one of styrene-b-butadiene-b-styrene (SBS), polyurethane, polyurethane acrylate, acrylate polymer, acrylate terpolymer, and silicone-based polymer.

Abstract: Provided is switch circuit including first and second transistors, a source pad connected to a second node of the second transistor through a first signal path and connected to a gate node of the first transistor through a second signal path, a gate pad connected to a gate node of the second transistor through a third signal path; and a drain pad connected to a first node of the first transistor through a fourth signal path, wherein a second node of the first transistor and a first node of the second transistor are connected to each other through a fifth signal path, and the gate node of the first transistor and the second node of the second transistor are connected to each other through a sixth signal path separated from the first and second signal paths.

Abstract: A vertical-cavity surface-emitting laser diode includes: a first resonator that has a plurality of semiconductor layers comprising a first current narrowing structure having a first conductive region and a first non-conductor region; a first electrode that supplies electric power to drive the first resonator; a second resonator that has a plurality of semiconductor layers comprising a second current narrowing structure having a second conductive region and a second non-conductive region and that is formed side by side with the first resonator, the second current narrowing structure being formed in same current narrowing layer as the layer where the first current narrowing structure is formed; and a coupling portion as defined herein; and an equivalent refractive index of the coupling portion is smaller than an equivalent refractive index of each of the first resonator and the second resonator.

Abstract: Provided are an apparatus and method for inputting a character based on a hand gesture. The apparatus includes a gesture recognition unit configured to recognize hand gestures of a user corresponding to horizontal directions, vertical directions, and diagonal directions, a control unit configured to control character input according to the directions of the recognized hand gestures, and a display unit configured to display a character pad for the character input and display characters input according to the directions of the hand gestures recognized on the character pad.

Abstract: The invention relates to methods of treating stress-sensitive psychiatric diseases arising from trauma in a subject by enhancing ghrelin signaling in the BLA of the subject. The invention also relates to methods of reversing ghrelin resistance.

Abstract: A frequency increasing processing method of a digital signal includes the following steps: S101, inputting a real signal trace collected in a certain period of time; S102, performing Hilbert transform on the real signal trace so as to obtain an instantaneous amplitude trace of the real signal trace; S103, based on the instantaneous amplitude trace, performing frequency increasing and polarity transform processing on the real signal trace so as to obtain a frequency increasing signal trace. Thus, a weak signal source can be identified without a large number of strong events. This shows advantages of environmental protection and cost reduction in the field of shale gas hydraulic fracturing micro-seismic monitoring. In addition, the zero polarity transform and frequency increasing processing in the present invention are simple in steps and are highly universal.

Abstract: A new acoustic tag and process are disclosed for identifying and tracking underwater hosts in up to three dimensions. The acoustic tag has an operation lifetime up to a year or longer at a pulse rate interval of about 15 seconds. The acoustic tag has a signal detection range up to at least about 500 meters that enhances detection probability.

Abstract: In accordance with the teachings described herein, systems and methods are provided for estimating quantiles for data stored in a distributed system. In one embodiment, an instruction is received to estimate a specified quantile for a variate in a set of data stored at a plurality of nodes in the distributed system. A plurality of data bins for the variate are defined that are each associated with a different range of data values in the set of data. Lower and upper quantile bounds for each of the plurality of data bins are determined based on the total number of data values that fall within each of the plurality of data bins. The specified quantile is estimated based on an identified one of the plurality of data bins that includes the specified quantile based on the lower and upper quantile bounds.

Abstract: A method for optical detection of residual soil on articles (such as medical instruments and equipment), after completion of a washing or a rinsing operation by a washer. A soil detection system provides an indication of soil on the articles by detecting luminescent radiation emanating from the soil in the presence of ambient light.