Abstract: This invention relates to methods for selecting a treatment, treating, and predicting survival time in subjects with cancer, such as colorectal cancer, based on tumor expression levels of chemokines, cytotoxic genes, and/or dendritic cell genes.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
August 2, 2016
Assignee:
H. Lee Moffitt Cancer Center and Research Institute, Inc.
Abstract: A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase I, carnitine palmitoyltransferase II, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial ?-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof.
Abstract: The present disclosure provides, in part, compositions comprising an antibody or antibody fragment that immunospecifically binds to MCH class I polypeptide-related sequence A (MICA), or an epitope thereof.
Type:
Grant
Filed:
September 12, 2013
Date of Patent:
August 2, 2016
Assignee:
Dana-Farber Cancer Institute, Inc.
Inventors:
Kai W. Wucherpfennig, Bettina Franz, Kenneth F. May, Jr., Glenn Dranoff, F. Stephen Hodi, Christopher Harvey
Abstract: A live biological specimen is imaged by generating a plurality of light sheets; directing the plurality of light sheets along an illumination axis through the biological specimen such that the light sheets spatially and temporally overlap within the biological specimen along an image plane, and optically interact with the biological specimen within the image plane; and recording, at each of a plurality of views, images of the fluorescence emitted along a detection axis from the biological specimen due to the optical interaction between the light sheets and the biological specimen. The temporal overlap is within a time shift that is less than a resolution time that corresponds to a spatial resolution limit of the microscope.
Abstract: An error calibrating apparatus of an array antenna system according to an exemplary embodiment of the present invention is an error calibrating apparatus of an array transmitting antenna system having a plurality of array antennas and includes a calibrating signal generator which generates an error calibrating signal as a single frequency signal, in an area which does not interfere with a passband of a transmitted signal; an array RF transmitter which upwardly converts the transmitted signal into an RF band to transmit the signal to the plurality of array antennas; an error calibration estimator which correlates the error calibrating signal and the receiving single frequency signal received by passing through the array RF transmitter to estimate a transfer function of the array RF transmitter and extract a filter coefficient using the estimated transfer function; and a complex filter which calibrates an error of the transmitted signal by applying the filter coefficient to output the corrected transmitted sign
Type:
Application
Filed:
January 12, 2016
Publication date:
July 28, 2016
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Jae Ho JUNG, Heon Kook KWON, Bong Hyuk PARK
Abstract: Provided is a hologram projection apparatus using an aspheric mirror, the apparatus including a spatial light modulator (SLM), a first mirror, a motor, and a second mirror, wherein the first mirror is configured to reflect modulated light output by the SLM, the motor is configured to rotate the first mirror, the second mirror is configured to reflect the modulated light reflected from the rotated first mirror, and the modulated light reflected from the second mirror, based on a degree of rotation of the first mirror, forms a consecutive viewing window in a horizontal direction.
Type:
Application
Filed:
January 21, 2016
Publication date:
July 28, 2016
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Hyun Eui KIM, Min Sik PARK, Jae Han KIM, Jin Woong KIM, Kyung Ae MOON
Abstract: Provided are a method and an apparatus for processing a transmission signal, which reduce a peak value to an appropriate magnitude by appropriately distorting a final transmission signal through implementation into simple hardware having a small memory and a small operation amount to effectively reduce a peak-to-average power ratio (PAPR) by effectively processing a signal for wireless communication in real time.
Type:
Application
Filed:
January 27, 2016
Publication date:
July 28, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: A copper catalyzed click chemistry ligation process is employed to bind azides and terminal acetylenes to provide 1,4-disubstituted 1,2,3-triazole triazoles. The process comprises contacting a solution of an organic azide and a terminal alkyne with a source of catalytic Ru ion to form a 1,4-disubstituted 1,2,3-triazole.
Type:
Application
Filed:
March 30, 2016
Publication date:
July 28, 2016
Applicant:
The Scripps Research Institute
Inventors:
K. Barry SHARPLESS, Valery FOKIN, Vsevold A. ROSTOVTSEV, Luke GREEN, Fahmi HIMO
Abstract: This invention relates to methods and compositions for preparing linear and cyclic polyolefins. More particularly, the invention relates to methods and compositions for preparing functionalized linear and cyclic polyolefins via olefin metathesis reactions. Polymer products produced via the olefin metathesis reactions of the invention may be utilized for a wide range of materials applications. The invention has utility in the fields of polymer and materials chemistry and manufacture.
Abstract: A bipolar plate and a fuel cell module using the same are provided. The bipolar plate includes a plate body and a temperature management component. The plate body has a plurality of reactive gas channels located on two opposite surfaces of the plate body, and the material of the plate body has a first thermal conductivity. The temperature management component is embedded within the plate body, and the material of the temperature management component has a second thermal conductivity. The first thermal conductivity is smaller than the second thermal conductivity. The temperature management component includes a plurality of tubes and a plurality of connecting elements, and the tubes communicate with each other through the connecting elements.
Type:
Application
Filed:
November 12, 2015
Publication date:
July 28, 2016
Applicant:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Inventors:
Cheng-Hong LIU, Cheng-Hao YANG, Ching-Ying HUANG, Wen-Lin WANG
Abstract: An apparatus for measuring rheological properties of a multi-phase fluid is provided. The apparatus includes a static chamber configured to contain a multi-phase fluid having at least a first phase and a second phase. The apparatus also includes a rotor member submersed in the multi-phase fluid in the static chamber. The rotor member is rotatable about a horizontal rotational axis within the static chamber and the static chamber and the rotor member are oriented in a substantially horizontal direction.
Abstract: An angle offset judging device (1) includes: an azimuth histogram generating section (126) for obtaining an appearance frequency of estimated azimuths; and an evaluating section (127) for making an evaluation of whether or not the appearance frequency thus obtained shows a tendency which is observed in a case where an azimuth is properly estimated under a binding condition concerning an advancing direction of a movement of a moving body.
Type:
Application
Filed:
May 14, 2014
Publication date:
July 28, 2016
Applicant:
National Institute of Advanced Industrial Science and Technology
Inventors:
Masakatsu KOUROGI, Takeshi KURATA, Tomoya ISHIKAWA, Takashi OKUMA
Abstract: Provided is a backflow cascade novel process for producing a lithium-7 isotope. The process comprises an upper backflow section, an extraction section, an enrichment section, a lower backflow section, and a product acquiring section. Upper backflow phase-conversion liquid and lower backflow phase-conversion liquid are respectively added to the upper backflow section and the lower backflow section, and upper backflow phase-conversion liquid and lower backflow phase-conversion liquid of the lithium material are controlled; the product is precisely acquired in the product acquiring section; an organic phase is added to the upper backflow section, and is recycled in the lower backflow section. By means of cascade connection with a high-performance liquid separator, environmental protection, high efficiency, and multi-level enrichment of the lithium-7 isotope are achieved, and a high-abundance lithium-7 isotope product is obtained.
Type:
Application
Filed:
March 28, 2014
Publication date:
July 28, 2016
Applicant:
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
Abstract: The present invention relates to a method and an apparatus for processing a signal, which are used for effectively reproducing a multimedia signal, and more particularly, to a method and an apparatus for processing a signal, which are used for implementing filtering for multimedia signal having a plurality of subbands with a low calculation amount.
Type:
Application
Filed:
September 17, 2014
Publication date:
July 28, 2016
Applicant:
WILUS INSTITUTE OF STANDARDS AND TECHNOLOGY INC.
Abstract: Provided is an apparatus for adjusting an envelope signal delay in an envelope-tracking power amplifier. The apparatus includes: an envelope signal providing unit configured to provide an envelope signal; a variable negative group delay unit configured to adjust a group delay of the envelope signal received from the envelope signal providing unit and output the adjusted envelope signal; an envelope modulator configured to modulate the envelope signal outputted from the variable negative group delay unit; a group delay difference detecting unit configured to detect a group delay difference between the envelope signal which is outputted from the envelope signal providing unit and the envelope signal which is outputted from the envelope modulator; and a control signal generating unit configured to generate a control signal to control a group delay value of the variable negative group delay unit according to the group delay difference.
Type:
Application
Filed:
January 15, 2016
Publication date:
July 28, 2016
Applicant:
Electronics and Telecommunications Research Institute
Inventors:
Seung Hyun JANG, Bong Hyuk PARK, Nam Sik RYU, Dong Seung KWON
Abstract: Provided herein are an optical zoom lens capable of actively zooming in and/or out and an apparatus using the same. The optical zoom lens may include an electro-active polymer layer configured to be deformable in response to an electric signal; a lens structure formed over the electro-active polymer layer; a first electrode formed on an upper surface of the electro-active polymer layer; a second electrode formed on a lower surface of the electro-active polymer layer; and a control circuit unit configured to apply a voltage to the first electrode and the second electrode. The optical zoom lens, having a structure of a combination of the polymer lens structure and the electro-active polymer actuator, is able to embody active variation in position of the polymer lens structure body and control therefor using deformation of the electro-active polymer layer by an electric signal.
Type:
Application
Filed:
January 26, 2016
Publication date:
July 28, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Sung Ryul YUN, Ki Uk KYUNG, Sun Tak PARK, Sae Kwang NAM, Bong Je PARK
Abstract: Provided are a method of manufacturing an electrode and a method of manufacturing a capacitor using the electrode. According to an embodiment of the inventive concept, provided is a method of manufacturing an electrode including forming stacked graphene films on a first substrate, separating the graphene films from the first substrate, cutting the graphene films to form graphene electrode parts, and transferring the graphene electrode parts to a second substrate, in which the graphene electrode parts cross a top surface of the second substrate.
Type:
Application
Filed:
January 27, 2016
Publication date:
July 28, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: Control of volume in bioreactors and associated systems is generally described. Feeding and/or sampling strategies can be employed, in some embodiments, such that the working volume within the bioreactor remains substantially constant.
Type:
Application
Filed:
August 22, 2014
Publication date:
July 28, 2016
Applicants:
Massachusetts Institute of Technology, Sanofi
Abstract: A smart antenna system according to an exemplary embodiment of the present invention including a beam forming antenna which includes an active antenna and a plurality of parasitic antennas, the system including: a reactance load which is connected to the parasitic antenna; a transceiver which transmits and receives a signal to the beam forming antenna; and an antenna adjusting block which tracks a signal source in real time using a plurality of beam patterns having the largest signal size and forms a beam in a direction having the largest signal size.
Type:
Application
Filed:
January 26, 2016
Publication date:
July 28, 2016
Applicant:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Inventors:
Young Kyun CHO, Bong Hyuk PARK, Jung Hoon OH, Jung Nam LEE, Gweon Do JO